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The map label for this gene is corA [H]

Identifier: 119357708

GI number: 119357708

Start: 2219546

End: 2220670

Strand: Reverse

Name: corA [H]

Synonym: Cpha266_1912

Alternate gene names: 119357708

Gene position: 2220670-2219546 (Counterclockwise)

Preceding gene: 119357709

Following gene: 119357706

Centisome position: 70.86

GC content: 44.71

Gene sequence:

>1125_bases
ATGAAAAGAAAAAAGAAAACGGAAGCCGGTGCAGAGGGGAGCCTTAACAGGTTGCATGCGGCCAAAAAAGTACTCAGAAG
CAGGGAGAAAACGTTCGGTCAGCCTGCAGGATCCCTTACCTATATTGGCGATCAACGGGTTGACAAACACGTTATCACGA
TTATAGGGTATGATGAAGGGCAACAGATCACGAAAACCATCACGGATGTTCATGAGTGCATTGAGCTTAAAAAGCAGTTC
AAGGTACTCTGGATCAATATTGATGGCGCCTATGATCCCGGGATCATGGAACAGATCGGTGCGGTGTTCGGAATAAACGC
ACTGACTCTTGAAGATATTCTGCATACCGGTCAGCGCCCGAAAGTCGAGGATTTTGAAGAGTATCTCTACATGGTGCTTC
AAATGATCGAATTTAATCAGGAAAAAGGTGAAATCATTCAGGAGCAGTTGAGTCTTATTATCGGCGACAACTATGTCATT
ACCTTTCAGGAAAAACCGGGAGATATGTTCGATCCTGTCCGGCAGCGGATCAGAGCCGCCGGTACCAAGTTGCGAAAATA
TTCTGCAGATTATCTTGCGTATTCATTGATCGACGCCGTTGTTGACGATTATTTTTCAATTCTTGAAGATATTGAAAATA
CCATTGATCGTCTTGATGTCGAACTGATAGAGAGTTACAGTCAACAGGCCTTTCAATCGCTCTACGCGCTTAAAAGGGAG
CTTATTATTCTCAGAAAATCGATCTGGCCTCTGAGAGAAGAGATCGGGAGTATCACGCGAGATGATTTTGCCGTCATAGG
AGACGGCGTCGAACCCTATTTCAGGGATGTGTATGATCATATTATTCTTGTGATCGACACTATCGAGGTATTCCGGGACA
TTGTTACCGGCATGCATGAAACCTATCTTGCCGGAATCAACAACCGGATGAACGAGATCATGAAGGTGCTGACCATTATT
GCCACGGTCTTTATGCCGCTTTCGTTTATTACCGGGGTGTTTGGCATGAACTTTCGTGTCATTCCCGGACTCGAGTGGCA
GTGGGGATTTTACGTGACAATCGGAGTAATGGGGGTGATTTATGGCGGTATGATGTTCTATTTTCATACAAGAAAGTGGT
TTTAA

Upstream 100 bases:

>100_bases
CGTTCAGCAATGTCGGGATATCTTCAGGGAGAGCGGATGGGATTGCCTTGAAGGTCCTTCACGCTTCTATGGTCGGTCAA
CCTGAGAAAATGTTGTTTCG

Downstream 100 bases:

>100_bases
CCGCTACAACCGCTGGTTATCAGTGGTTTTCTTCATATTTTCCTTTTTTCTTCTGACCGGTAAAATAGGTTAGTCCGGCG
ACAACAAAACCGATGGCTCC

Product: magnesium and cobalt transport protein CorA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MKRKKKTEAGAEGSLNRLHAAKKVLRSREKTFGQPAGSLTYIGDQRVDKHVITIIGYDEGQQITKTITDVHECIELKKQF
KVLWINIDGAYDPGIMEQIGAVFGINALTLEDILHTGQRPKVEDFEEYLYMVLQMIEFNQEKGEIIQEQLSLIIGDNYVI
TFQEKPGDMFDPVRQRIRAAGTKLRKYSADYLAYSLIDAVVDDYFSILEDIENTIDRLDVELIESYSQQAFQSLYALKRE
LIILRKSIWPLREEIGSITRDDFAVIGDGVEPYFRDVYDHIILVIDTIEVFRDIVTGMHETYLAGINNRMNEIMKVLTII
ATVFMPLSFITGVFGMNFRVIPGLEWQWGFYVTIGVMGVIYGGMMFYFHTRKWF

Sequences:

>Translated_374_residues
MKRKKKTEAGAEGSLNRLHAAKKVLRSREKTFGQPAGSLTYIGDQRVDKHVITIIGYDEGQQITKTITDVHECIELKKQF
KVLWINIDGAYDPGIMEQIGAVFGINALTLEDILHTGQRPKVEDFEEYLYMVLQMIEFNQEKGEIIQEQLSLIIGDNYVI
TFQEKPGDMFDPVRQRIRAAGTKLRKYSADYLAYSLIDAVVDDYFSILEDIENTIDRLDVELIESYSQQAFQSLYALKRE
LIILRKSIWPLREEIGSITRDDFAVIGDGVEPYFRDVYDHIILVIDTIEVFRDIVTGMHETYLAGINNRMNEIMKVLTII
ATVFMPLSFITGVFGMNFRVIPGLEWQWGFYVTIGVMGVIYGGMMFYFHTRKWF
>Mature_374_residues
MKRKKKTEAGAEGSLNRLHAAKKVLRSREKTFGQPAGSLTYIGDQRVDKHVITIIGYDEGQQITKTITDVHECIELKKQF
KVLWINIDGAYDPGIMEQIGAVFGINALTLEDILHTGQRPKVEDFEEYLYMVLQMIEFNQEKGEIIQEQLSLIIGDNYVI
TFQEKPGDMFDPVRQRIRAAGTKLRKYSADYLAYSLIDAVVDDYFSILEDIENTIDRLDVELIESYSQQAFQSLYALKRE
LIILRKSIWPLREEIGSITRDDFAVIGDGVEPYFRDVYDHIILVIDTIEVFRDIVTGMHETYLAGINNRMNEIMKVLTII
ATVFMPLSFITGVFGMNFRVIPGLEWQWGFYVTIGVMGVIYGGMMFYFHTRKWF

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI1787604, Length=180, Percent_Identity=24.4444444444444, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 43127; Mature: 43127

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKKKTEAGAEGSLNRLHAAKKVLRSREKTFGQPAGSLTYIGDQRVDKHVITIIGYDEG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEECCCC
QQITKTITDVHECIELKKQFKVLWINIDGAYDPGIMEQIGAVFGINALTLEDILHTGQRP
HHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCC
KVEDFEEYLYMVLQMIEFNQEKGEIIQEQLSLIIGDNYVITFQEKPGDMFDPVRQRIRAA
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHH
GTKLRKYSADYLAYSLIDAVVDDYFSILEDIENTIDRLDVELIESYSQQAFQSLYALKRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIILRKSIWPLREEIGSITRDDFAVIGDGVEPYFRDVYDHIILVIDTIEVFRDIVTGMHE
HHHHHHHHHHHHHHHCCCCCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYLAGINNRMNEIMKVLTIIATVFMPLSFITGVFGMNFRVIPGLEWQWGFYVTIGVMGVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHH
YGGMMFYFHTRKWF
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKRKKKTEAGAEGSLNRLHAAKKVLRSREKTFGQPAGSLTYIGDQRVDKHVITIIGYDEG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEECCCC
QQITKTITDVHECIELKKQFKVLWINIDGAYDPGIMEQIGAVFGINALTLEDILHTGQRP
HHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCC
KVEDFEEYLYMVLQMIEFNQEKGEIIQEQLSLIIGDNYVITFQEKPGDMFDPVRQRIRAA
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHH
GTKLRKYSADYLAYSLIDAVVDDYFSILEDIENTIDRLDVELIESYSQQAFQSLYALKRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIILRKSIWPLREEIGSITRDDFAVIGDGVEPYFRDVYDHIILVIDTIEVFRDIVTGMHE
HHHHHHHHHHHHHHHCCCCCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYLAGINNRMNEIMKVLTIIATVFMPLSFITGVFGMNFRVIPGLEWQWGFYVTIGVMGVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHH
YGGMMFYFHTRKWF
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]