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The map label for this gene is ahpC [C]

Identifier: 119357674

GI number: 119357674

Start: 2176001

End: 2176591

Strand: Reverse

Name: ahpC [C]

Synonym: Cpha266_1878

Alternate gene names: 119357674

Gene position: 2176591-2176001 (Counterclockwise)

Preceding gene: 119357676

Following gene: 119357671

Centisome position: 69.45

GC content: 48.56

Gene sequence:

>591_bases
ATGGGCGTACTGGTTGGTCGCAAGGCACCGGAATTTTGTGTGGAGGCGGTAACGGGCGGGTCCCGGTTTGTTGATGCATG
CCGTCTTTCGGATTATGCGGGAAAGTATGTGGTGTTGTTTTTCTACCCGCTTGATTTTACGTTTGTTTGTCCTACCGAGC
TTCATGCATTTCAGGACAAGCTTGATGAGTTCACAAAGAGAAACGTTGAGGTTATCGGTTGTTCGGTTGATTCGAAGTTT
TCTCACTTTGCATGGCTGCAGACCCCGAGAAACCGGGGAGGAATTGAAGGGGTGACCTATACGCTCCTTTCGGATATCAA
TAAAACCGTTTCATCCGATTACGATGTTCTGGTCGATGGAGCAGGCATATCGCTTCGAGGCTTGTTTCTTATTGATCGCG
AGGGTGTTGTGCGCCATCAGGTTGTCAATGATCTCGGGCTCGGCAGAAATGTTGATGAGGTACTCAGAATGATTGATGCC
TTGCAGTTTACCGAGGAGTTTGGTGAGGTTTGTCCTGCAAACTGGAACAAGGGCGATAAAACCATGAAGCCTGATGATGA
GGGGCTCAAAGAGTTCTTCAAGGATGCCTGA

Upstream 100 bases:

>100_bases
TCTGCCTGTTTATTTGCAGAAAATTCTTTGATGTCTTATATTGGACTAAATATGTCTTATTTATTGGTTTTTTACCCTGA
AACAAAAAAAGGAGAATAGT

Downstream 100 bases:

>100_bases
GCTGACCGGGTTTTTGATAATTCCGGCAACTCCCCTGTTGGAGGGTTGTTGCCGGAATTAATTTTATGCAACATCTCAGT
ATGCTTTTGCAAACACTGCC

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MGVLVGRKAPEFCVEAVTGGSRFVDACRLSDYAGKYVVLFFYPLDFTFVCPTELHAFQDKLDEFTKRNVEVIGCSVDSKF
SHFAWLQTPRNRGGIEGVTYTLLSDINKTVSSDYDVLVDGAGISLRGLFLIDREGVVRHQVVNDLGLGRNVDEVLRMIDA
LQFTEEFGEVCPANWNKGDKTMKPDDEGLKEFFKDA

Sequences:

>Translated_196_residues
MGVLVGRKAPEFCVEAVTGGSRFVDACRLSDYAGKYVVLFFYPLDFTFVCPTELHAFQDKLDEFTKRNVEVIGCSVDSKF
SHFAWLQTPRNRGGIEGVTYTLLSDINKTVSSDYDVLVDGAGISLRGLFLIDREGVVRHQVVNDLGLGRNVDEVLRMIDA
LQFTEEFGEVCPANWNKGDKTMKPDDEGLKEFFKDA
>Mature_195_residues
GVLVGRKAPEFCVEAVTGGSRFVDACRLSDYAGKYVVLFFYPLDFTFVCPTELHAFQDKLDEFTKRNVEVIGCSVDSKFS
HFAWLQTPRNRGGIEGVTYTLLSDINKTVSSDYDVLVDGAGISLRGLFLIDREGVVRHQVVNDLGLGRNVDEVLRMIDAL
QFTEEFGEVCPANWNKGDKTMKPDDEGLKEFFKDA

Specific function: Reduces peroxides. May play an important role in eliminating peroxides generated during metabolism [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4505591, Length=189, Percent_Identity=53.968253968254, Blast_Score=214, Evalue=3e-56,
Organism=Homo sapiens, GI32455266, Length=189, Percent_Identity=53.968253968254, Blast_Score=214, Evalue=3e-56,
Organism=Homo sapiens, GI32455264, Length=189, Percent_Identity=53.968253968254, Blast_Score=214, Evalue=3e-56,
Organism=Homo sapiens, GI5802974, Length=190, Percent_Identity=53.6842105263158, Blast_Score=213, Evalue=7e-56,
Organism=Homo sapiens, GI32483377, Length=187, Percent_Identity=54.0106951871658, Blast_Score=212, Evalue=2e-55,
Organism=Homo sapiens, GI32189392, Length=189, Percent_Identity=52.3809523809524, Blast_Score=210, Evalue=8e-55,
Organism=Homo sapiens, GI5453549, Length=189, Percent_Identity=49.2063492063492, Blast_Score=203, Evalue=1e-52,
Organism=Homo sapiens, GI33188454, Length=83, Percent_Identity=55.421686746988, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI4758638, Length=206, Percent_Identity=31.5533980582524, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1786822, Length=182, Percent_Identity=34.0659340659341, Blast_Score=119, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI193204376, Length=191, Percent_Identity=51.3089005235602, Blast_Score=203, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI32565831, Length=191, Percent_Identity=51.3089005235602, Blast_Score=203, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17554494, Length=163, Percent_Identity=52.1472392638037, Blast_Score=187, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI25153706, Length=165, Percent_Identity=26.6666666666667, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323613, Length=196, Percent_Identity=46.4285714285714, Blast_Score=186, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6320661, Length=192, Percent_Identity=46.3541666666667, Blast_Score=184, Evalue=9e-48,
Organism=Saccharomyces cerevisiae, GI6319407, Length=200, Percent_Identity=35.5, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17738015, Length=194, Percent_Identity=54.1237113402062, Blast_Score=212, Evalue=1e-55,
Organism=Drosophila melanogaster, GI17157991, Length=188, Percent_Identity=53.1914893617021, Blast_Score=204, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24641739, Length=188, Percent_Identity=53.1914893617021, Blast_Score=204, Evalue=3e-53,
Organism=Drosophila melanogaster, GI21357347, Length=193, Percent_Identity=50.7772020725389, Blast_Score=203, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24656348, Length=191, Percent_Identity=49.2146596858639, Blast_Score=200, Evalue=6e-52,
Organism=Drosophila melanogaster, GI17864676, Length=191, Percent_Identity=49.2146596858639, Blast_Score=200, Evalue=6e-52,
Organism=Drosophila melanogaster, GI24581278, Length=184, Percent_Identity=32.0652173913043, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24652436, Length=204, Percent_Identity=33.8235294117647, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17975518, Length=204, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24652434, Length=204, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=5e-20,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21936; Mature: 21805

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVLVGRKAPEFCVEAVTGGSRFVDACRLSDYAGKYVVLFFYPLDFTFVCPTELHAFQDK
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEEECCEEEECCHHHHHHHHH
LDEFTKRNVEVIGCSVDSKFSHFAWLQTPRNRGGIEGVTYTLLSDINKTVSSDYDVLVDG
HHHHHHCCEEEEEECCCCCCHHHHEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEC
AGISLRGLFLIDREGVVRHQVVNDLGLGRNVDEVLRMIDALQFTEEFGEVCPANWNKGDK
CCCEEEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TMKPDDEGLKEFFKDA
CCCCCHHHHHHHHHCC
>Mature Secondary Structure 
GVLVGRKAPEFCVEAVTGGSRFVDACRLSDYAGKYVVLFFYPLDFTFVCPTELHAFQDK
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEEECCEEEECCHHHHHHHHH
LDEFTKRNVEVIGCSVDSKFSHFAWLQTPRNRGGIEGVTYTLLSDINKTVSSDYDVLVDG
HHHHHHCCEEEEEECCCCCCHHHHEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEC
AGISLRGLFLIDREGVVRHQVVNDLGLGRNVDEVLRMIDALQFTEEFGEVCPANWNKGDK
CCCEEEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TMKPDDEGLKEFFKDA
CCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]