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The map label for this gene is gap [H]

Identifier: 119357666

GI number: 119357666

Start: 2167478

End: 2168482

Strand: Direct

Name: gap [H]

Synonym: Cpha266_1870

Alternate gene names: 119357666

Gene position: 2167478-2168482 (Clockwise)

Preceding gene: 119357665

Following gene: 119357667

Centisome position: 69.16

GC content: 49.45

Gene sequence:

>1005_bases
ATGGCTAAAGTGAAAGTCGGCATTAATGGATTTGGCCGAATCGGACGTCTGGTGCTTCGGCAGGCAATGAACAACCCGAA
TTTTGAAATTGTTGCTATCAACGATCTGTGCGATACCAAAACCCTCGCACATCTGCTCAAGTATGACTCAACACACAAGA
AATTTTCAGGTGAAGTACGGGTCGAAGGTGAAAACCTTGTCATCAACGGCCAGACCGTTACCATCAGCGCACAGCGCGAT
CCCCTCCAGCTTCCATGGAAGGAACTCGGATGTGACCTGGTAGTTGAATCAACAGGTATTTTCACATCGAGAGAGGCTGC
TTCAAAGCATATCACTGCCGGGGCAAAAAAGGTTATCATTTCCGCTCCCGCAAAAGACAAGATTGATGCAACCATTGTGA
TGGGCGTCAATGACAGCATCATTACCGGAAATGAGGAGATCATTTCGAATGCAAGCTGCACAACCAACTGTCTGGCCCCG
ATGGTAAAAGTTCTTCAGGACAGCTTTGGTATCGCCCAGGGATTCATGACCACGGTGCACGCCTACACCAATGATCAGAA
CATCCTCGATTTACCGCACAAGGATCTTCGTCGCGCACGCTCTGCCGCACTTTCGATCATCCCGACCAGTACCGGTGCAG
CAAAGGCTATCGGAGAGGTAATTCCTGAACTTGCCGGAATTCTTGACGGGTTTGCCATGAGAGTACCTGTACCTGACGGC
TCCGTCACTGATCTTACCGTCATCCTGAACCGCGAGACCTCAAAAGCAGAGGTTAATGCAGCGGTTAAAGCCGCCGCTGA
CGGCCCGATGAAAGGATATCTCGAATACTGTGAAGACCCGATCGTTTCACAGGACATCGTAGGCAATGCCCACTCCTGCA
TTTTCGACTCCTTGTTGACTATGAGCGTAGGAAAAATGGTTAAAGTTGTCGGCTGGTATGACAACGAACTTGGTTATGCC
ACAAGGGTCACCGACCTTCTCAATATTTACTCGAAGTACGTCTGA

Upstream 100 bases:

>100_bases
TAGTTAGTTTATCTTCCAAAGTGTTTAAGGACATAAAACCGGTTACCATGATGCATAGTTCTGCACAGGTAACCATAACC
ACAACTATTGAAACGTTATT

Downstream 100 bases:

>100_bases
CCGATCATTCCGTTTGAAAAAAAAGAGGGTTCCGCATGGGGCTCTCTTTTTTTACGGGCAAAACGGCATCCGTTTTCCTC
GCGGGACCGCTGCAAGCAAT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAKVKVGINGFGRIGRLVLRQAMNNPNFEIVAINDLCDTKTLAHLLKYDSTHKKFSGEVRVEGENLVINGQTVTISAQRD
PLQLPWKELGCDLVVESTGIFTSREAASKHITAGAKKVIISAPAKDKIDATIVMGVNDSIITGNEEIISNASCTTNCLAP
MVKVLQDSFGIAQGFMTTVHAYTNDQNILDLPHKDLRRARSAALSIIPTSTGAAKAIGEVIPELAGILDGFAMRVPVPDG
SVTDLTVILNRETSKAEVNAAVKAAADGPMKGYLEYCEDPIVSQDIVGNAHSCIFDSLLTMSVGKMVKVVGWYDNELGYA
TRVTDLLNIYSKYV

Sequences:

>Translated_334_residues
MAKVKVGINGFGRIGRLVLRQAMNNPNFEIVAINDLCDTKTLAHLLKYDSTHKKFSGEVRVEGENLVINGQTVTISAQRD
PLQLPWKELGCDLVVESTGIFTSREAASKHITAGAKKVIISAPAKDKIDATIVMGVNDSIITGNEEIISNASCTTNCLAP
MVKVLQDSFGIAQGFMTTVHAYTNDQNILDLPHKDLRRARSAALSIIPTSTGAAKAIGEVIPELAGILDGFAMRVPVPDG
SVTDLTVILNRETSKAEVNAAVKAAADGPMKGYLEYCEDPIVSQDIVGNAHSCIFDSLLTMSVGKMVKVVGWYDNELGYA
TRVTDLLNIYSKYV
>Mature_333_residues
AKVKVGINGFGRIGRLVLRQAMNNPNFEIVAINDLCDTKTLAHLLKYDSTHKKFSGEVRVEGENLVINGQTVTISAQRDP
LQLPWKELGCDLVVESTGIFTSREAASKHITAGAKKVIISAPAKDKIDATIVMGVNDSIITGNEEIISNASCTTNCLAPM
VKVLQDSFGIAQGFMTTVHAYTNDQNILDLPHKDLRRARSAALSIIPTSTGAAKAIGEVIPELAGILDGFAMRVPVPDGS
VTDLTVILNRETSKAEVNAAVKAAADGPMKGYLEYCEDPIVSQDIVGNAHSCIFDSLLTMSVGKMVKVVGWYDNELGYAT
RVTDLLNIYSKYV

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=330, Percent_Identity=50.9090909090909, Blast_Score=325, Evalue=3e-89,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=49.5440729483283, Blast_Score=318, Evalue=5e-87,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=52.5679758308157, Blast_Score=346, Evalue=9e-97,
Organism=Escherichia coli, GI1789295, Length=326, Percent_Identity=42.0245398773006, Blast_Score=278, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17534679, Length=336, Percent_Identity=51.1904761904762, Blast_Score=325, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI17534677, Length=336, Percent_Identity=50.8928571428571, Blast_Score=325, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=50.7418397626113, Blast_Score=320, Evalue=8e-88,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=50.7418397626113, Blast_Score=320, Evalue=9e-88,
Organism=Saccharomyces cerevisiae, GI6321631, Length=332, Percent_Identity=51.2048192771084, Blast_Score=345, Evalue=5e-96,
Organism=Saccharomyces cerevisiae, GI6322468, Length=332, Percent_Identity=50.9036144578313, Blast_Score=341, Evalue=7e-95,
Organism=Saccharomyces cerevisiae, GI6322409, Length=332, Percent_Identity=49.6987951807229, Blast_Score=336, Evalue=3e-93,
Organism=Drosophila melanogaster, GI17933600, Length=326, Percent_Identity=50.6134969325153, Blast_Score=321, Evalue=6e-88,
Organism=Drosophila melanogaster, GI18110149, Length=326, Percent_Identity=50.6134969325153, Blast_Score=321, Evalue=6e-88,
Organism=Drosophila melanogaster, GI85725000, Length=326, Percent_Identity=50, Blast_Score=317, Evalue=5e-87,
Organism=Drosophila melanogaster, GI22023983, Length=326, Percent_Identity=50, Blast_Score=317, Evalue=5e-87,
Organism=Drosophila melanogaster, GI19922412, Length=332, Percent_Identity=47.289156626506, Blast_Score=296, Evalue=1e-80,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35941; Mature: 35810

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVKVGINGFGRIGRLVLRQAMNNPNFEIVAINDLCDTKTLAHLLKYDSTHKKFSGEVR
CCEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHCCCEEE
VEGENLVINGQTVTISAQRDPLQLPWKELGCDLVVESTGIFTSREAASKHITAGAKKVII
EECCEEEEECEEEEEEECCCCCCCCHHHCCCEEEEECCCCEECHHHHHHHHCCCCCEEEE
SAPAKDKIDATIVMGVNDSIITGNEEIISNASCTTNCLAPMVKVLQDSFGIAQGFMTTVH
ECCCCCCCCEEEEEECCCCEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHE
AYTNDQNILDLPHKDLRRARSAALSIIPTSTGAAKAIGEVIPELAGILDGFAMRVPVPDG
EECCCCCEEECCHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCC
SVTDLTVILNRETSKAEVNAAVKAAADGPMKGYLEYCEDPIVSQDIVGNAHSCIFDSLLT
CCEEEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHH
MSVGKMVKVVGWYDNELGYATRVTDLLNIYSKYV
HHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKVKVGINGFGRIGRLVLRQAMNNPNFEIVAINDLCDTKTLAHLLKYDSTHKKFSGEVR
CEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHCCCEEE
VEGENLVINGQTVTISAQRDPLQLPWKELGCDLVVESTGIFTSREAASKHITAGAKKVII
EECCEEEEECEEEEEEECCCCCCCCHHHCCCEEEEECCCCEECHHHHHHHHCCCCCEEEE
SAPAKDKIDATIVMGVNDSIITGNEEIISNASCTTNCLAPMVKVLQDSFGIAQGFMTTVH
ECCCCCCCCEEEEEECCCCEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHE
AYTNDQNILDLPHKDLRRARSAALSIIPTSTGAAKAIGEVIPELAGILDGFAMRVPVPDG
EECCCCCEEECCHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCC
SVTDLTVILNRETSKAEVNAAVKAAADGPMKGYLEYCEDPIVSQDIVGNAHSCIFDSLLT
CCEEEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHH
MSVGKMVKVVGWYDNELGYATRVTDLLNIYSKYV
HHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2684782; 2227448; 2656407; 7408868; 193030; 3586018; 9175858 [H]