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The map label for this gene is aprE [H]

Identifier: 119357544

GI number: 119357544

Start: 1973891

End: 1975072

Strand: Reverse

Name: aprE [H]

Synonym: Cpha266_1747

Alternate gene names: 119357544

Gene position: 1975072-1973891 (Counterclockwise)

Preceding gene: 119357545

Following gene: 119357543

Centisome position: 63.02

GC content: 53.47

Gene sequence:

>1182_bases
ATGCATAGTCAAAAAGAAGAAGGAGAAAAACAGCCTGTTGCGACTGAAAAGGCTGCCGAAGTTCACGTTAAAAGCTATCG
GGATACCGGCAGTACGATCCGTCTCGGAATATGGATACTTCTTGTCGGCTTTGGCGGTTTTCTGTTGTGGGCGGCATTTG
CACCGCTTGACGAAGGAGTTCCCTGCCAGGGCGTTGTCAGTATTGCTACCAAGCGAAAGGTCGTTGAGCATCTTCGAGGT
GGTACCGTTGAGAAGGTTGAGGTGCGGGAAGGTCAGATCGTACAGGAGGGAGAGGTGCTGATGAGACTTGACAGCCAGAC
GGCAAGGGCGCGGTACGATGAGATTCATCAGCACTATATCGGTACAAGAGCTACGGCAGACAGGCTGCTTGCGGAGATGA
GCGGAGCAGGATCAATTGCTTTTCACCATGATCTTCTTGCCGATCCGGATCGAACTCTTGCCGAACAGAATATGCGGACA
CAGAGGCAGCTTTTTCTCTCCCGCCAGGTTACGCTAAGGATTCTCAATGAACAGCTCTCTGGTATTGTCTCGCTTGTCAA
GGAAGGTTATGCCCCCTTGAGTCAGCAGCACGAGCTGGAGCTGAAGATTGCAGAGCTGAAGAGTGCAACAGCCTCGCAAC
TCGCACAGGTGCAGCTTGAAGTAGAAGCCGACGCGGAAAAGACTCGAGCCCTTGCTGAAGAGCTTGCCGATACTGAACTC
CGATCTCCCGCCTCAGGACAGGTGGTGGGCCTGCAAGTACAGACCGTTGGTGCCGTGATTCAGCCAGGTCAGAAGGTTAT
GGATATCGTTCCGCTTCATGAAGGCCTGCTCATAGATGCCAAGGTTGCCCCGCATCTGATCGACAGCATCCGTAAGGGAC
TGCCGGTGGACGTGAGCTTTTCCTCATTTGCACATGCGCCCCAGCTTGTTGTGCAGGCTGTGGTTGCTTCGATCTCAAAA
GATATTATTACGGACCCGCAGACAAACCCGTCGATGCCTGGAGCCTCCTATTACCTTGCCCGGATTGCGGTGACCCCGCA
TGGACTCAACTCTCTCGGAAATCGTCAGATGCAGCCGGGAATGCCGGTACAGGTGGTTATTAAAACCGGGGAACGTTCCC
TGCTGACCTACCTGATTGATCCGCTGCTCAAGCGGATTACAGTCTCCATGAAGGAGGAGTGA

Upstream 100 bases:

>100_bases
CAAGAGATGAGGTTATTGCATCATTGCGCAATGAAAGCACAAAAGCGTCGGTAGTGCCGGCAGAATGATGCGGTTTTTGA
AACAGGTATAAAGGAGTGCC

Downstream 100 bases:

>100_bases
GGGTATCTTCATGAATTTCTTTTTTTGAAAAAGGTCGCTCGAAAGAGCTGTTAACGAAACGCGAAGTCTGTATTGAACAT
GAAGAGTTTTTGGTATGTAA

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MHSQKEEGEKQPVATEKAAEVHVKSYRDTGSTIRLGIWILLVGFGGFLLWAAFAPLDEGVPCQGVVSIATKRKVVEHLRG
GTVEKVEVREGQIVQEGEVLMRLDSQTARARYDEIHQHYIGTRATADRLLAEMSGAGSIAFHHDLLADPDRTLAEQNMRT
QRQLFLSRQVTLRILNEQLSGIVSLVKEGYAPLSQQHELELKIAELKSATASQLAQVQLEVEADAEKTRALAEELADTEL
RSPASGQVVGLQVQTVGAVIQPGQKVMDIVPLHEGLLIDAKVAPHLIDSIRKGLPVDVSFSSFAHAPQLVVQAVVASISK
DIITDPQTNPSMPGASYYLARIAVTPHGLNSLGNRQMQPGMPVQVVIKTGERSLLTYLIDPLLKRITVSMKEE

Sequences:

>Translated_393_residues
MHSQKEEGEKQPVATEKAAEVHVKSYRDTGSTIRLGIWILLVGFGGFLLWAAFAPLDEGVPCQGVVSIATKRKVVEHLRG
GTVEKVEVREGQIVQEGEVLMRLDSQTARARYDEIHQHYIGTRATADRLLAEMSGAGSIAFHHDLLADPDRTLAEQNMRT
QRQLFLSRQVTLRILNEQLSGIVSLVKEGYAPLSQQHELELKIAELKSATASQLAQVQLEVEADAEKTRALAEELADTEL
RSPASGQVVGLQVQTVGAVIQPGQKVMDIVPLHEGLLIDAKVAPHLIDSIRKGLPVDVSFSSFAHAPQLVVQAVVASISK
DIITDPQTNPSMPGASYYLARIAVTPHGLNSLGNRQMQPGMPVQVVIKTGERSLLTYLIDPLLKRITVSMKEE
>Mature_393_residues
MHSQKEEGEKQPVATEKAAEVHVKSYRDTGSTIRLGIWILLVGFGGFLLWAAFAPLDEGVPCQGVVSIATKRKVVEHLRG
GTVEKVEVREGQIVQEGEVLMRLDSQTARARYDEIHQHYIGTRATADRLLAEMSGAGSIAFHHDLLADPDRTLAEQNMRT
QRQLFLSRQVTLRILNEQLSGIVSLVKEGYAPLSQQHELELKIAELKSATASQLAQVQLEVEADAEKTRALAEELADTEL
RSPASGQVVGLQVQTVGAVIQPGQKVMDIVPLHEGLLIDAKVAPHLIDSIRKGLPVDVSFSSFAHAPQLVVQAVVASISK
DIITDPQTNPSMPGASYYLARIAVTPHGLNSLGNRQMQPGMPVQVVIKTGERSLLTYLIDPLLKRITVSMKEE

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42936; Mature: 42936

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSQKEEGEKQPVATEKAAEVHVKSYRDTGSTIRLGIWILLVGFGGFLLWAAFAPLDEGV
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PCQGVVSIATKRKVVEHLRGGTVEKVEVREGQIVQEGEVLMRLDSQTARARYDEIHQHYI
CCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCHHHEEECCHHHHHHHHHHHHHHH
GTRATADRLLAEMSGAGSIAFHHDLLADPDRTLAEQNMRTQRQLFLSRQVTLRILNEQLS
CCHHHHHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIVSLVKEGYAPLSQQHELELKIAELKSATASQLAQVQLEVEADAEKTRALAEELADTEL
HHHHHHHHCCCCCCCCCHHEEHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHH
RSPASGQVVGLQVQTVGAVIQPGQKVMDIVPLHEGLLIDAKVAPHLIDSIRKGLPVDVSF
CCCCCCCEEEEEEHHHHHHHCCCHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCCCEEH
SSFAHAPQLVVQAVVASISKDIITDPQTNPSMPGASYYLARIAVTPHGLNSLGNRQMQPG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCHHHHCCCCCCCC
MPVQVVIKTGERSLLTYLIDPLLKRITVSMKEE
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHSQKEEGEKQPVATEKAAEVHVKSYRDTGSTIRLGIWILLVGFGGFLLWAAFAPLDEGV
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PCQGVVSIATKRKVVEHLRGGTVEKVEVREGQIVQEGEVLMRLDSQTARARYDEIHQHYI
CCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCHHHEEECCHHHHHHHHHHHHHHH
GTRATADRLLAEMSGAGSIAFHHDLLADPDRTLAEQNMRTQRQLFLSRQVTLRILNEQLS
CCHHHHHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIVSLVKEGYAPLSQQHELELKIAELKSATASQLAQVQLEVEADAEKTRALAEELADTEL
HHHHHHHHCCCCCCCCCHHEEHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHH
RSPASGQVVGLQVQTVGAVIQPGQKVMDIVPLHEGLLIDAKVAPHLIDSIRKGLPVDVSF
CCCCCCCEEEEEEHHHHHHHCCCHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCCCEEH
SSFAHAPQLVVQAVVASISKDIITDPQTNPSMPGASYYLARIAVTPHGLNSLGNRQMQPG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCHHHHCCCCCCCC
MPVQVVIKTGERSLLTYLIDPLLKRITVSMKEE
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]