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The map label for this gene is trx1 [H]

Identifier: 119357517

GI number: 119357517

Start: 1947571

End: 1947879

Strand: Reverse

Name: trx1 [H]

Synonym: Cpha266_1719

Alternate gene names: 119357517

Gene position: 1947879-1947571 (Counterclockwise)

Preceding gene: 119357518

Following gene: 119357515

Centisome position: 62.16

GC content: 53.4

Gene sequence:

>309_bases
ATGGCTCAGTCACTTGATGATCTTATAAAAACAAGCCAGCTTCCCGTTTTTGTGGATTTCTGGGCGGAATGGTGCGCTCC
CTGCCGGAGCGTAGCCCCTGTGGTCAAACAGCTTGCACAGGAATTCAACGGACGATTGACGGTTGTAAAGGTGAATGTCG
ATAAACAACCCGATGCAGCATCCCGACACCAGGTGCAGAGCATCCCTGCGCTCATGCTGTTTCATCGGGGAGAGCTGAAA
TGGCGTACCGCCGGCGCCATCTCCTATCCGCAACTGAAAGCTGAGGTGATGAAGGTGCTTGGTGCATGA

Upstream 100 bases:

>100_bases
AATGGAGAAGTATTGCAGCGTAGCGGCCATGCTCAGGGCCTCGGGATGTGCAGTTACATGGAGTTCTGAAATTATTTAAC
CCGATAATCAATACTCTCTT

Downstream 100 bases:

>100_bases
CCGACAGGAAAAAGAGTCTTTCATCGCGGGTATTGCGATGACATGTTTTGACATGTGAAACAGCGTTATCAGGAAACGCA
GAGCCCCGGCACGGCATAAA

Product: thioredoxin

Products: NA

Alternate protein names: Trx-1 [H]

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MAQSLDDLIKTSQLPVFVDFWAEWCAPCRSVAPVVKQLAQEFNGRLTVVKVNVDKQPDAASRHQVQSIPALMLFHRGELK
WRTAGAISYPQLKAEVMKVLGA

Sequences:

>Translated_102_residues
MAQSLDDLIKTSQLPVFVDFWAEWCAPCRSVAPVVKQLAQEFNGRLTVVKVNVDKQPDAASRHQVQSIPALMLFHRGELK
WRTAGAISYPQLKAEVMKVLGA
>Mature_101_residues
AQSLDDLIKTSQLPVFVDFWAEWCAPCRSVAPVVKQLAQEFNGRLTVVKVNVDKQPDAASRHQVQSIPALMLFHRGELKW
RTAGAISYPQLKAEVMKVLGA

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=95, Percent_Identity=29.4736842105263, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082331, Length=91, Percent_Identity=41.7582417582418, Blast_Score=96, Evalue=4e-22,
Organism=Escherichia coli, GI1788936, Length=86, Percent_Identity=41.8604651162791, Blast_Score=83, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323072, Length=85, Percent_Identity=32.9411764705882, Blast_Score=62, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321648, Length=85, Percent_Identity=31.7647058823529, Blast_Score=62, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639826, Length=72, Percent_Identity=37.5, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28573567, Length=83, Percent_Identity=31.3253012048193, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11376; Mature: 11245

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSLDDLIKTSQLPVFVDFWAEWCAPCRSVAPVVKQLAQEFNGRLTVVKVNVDKQPDAA
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCH
SRHQVQSIPALMLFHRGELKWRTAGAISYPQLKAEVMKVLGA
HHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AQSLDDLIKTSQLPVFVDFWAEWCAPCRSVAPVVKQLAQEFNGRLTVVKVNVDKQPDAA
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCH
SRHQVQSIPALMLFHRGELKWRTAGAISYPQLKAEVMKVLGA
HHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]