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The map label for this gene is dnaX [H]

Identifier: 119357453

GI number: 119357453

Start: 1880134

End: 1881327

Strand: Reverse

Name: dnaX [H]

Synonym: Cpha266_1652

Alternate gene names: 119357453

Gene position: 1881327-1880134 (Counterclockwise)

Preceding gene: 119357454

Following gene: 119357452

Centisome position: 60.03

GC content: 47.24

Gene sequence:

>1194_bases
ATGAGTTATCAGGTTATAGCAAGAAAGTACCGTCCTAAAAAATTTGCCGACATTACGGCGCAGGAACATATAACCCGGAC
TATTCAGAATTCGCTTCGTATGGGCAGGCTTGGTCATGGTTATATTTTTTCGGGTTTGCGCGGTGTTGGTAAAACAACCG
CTGCCCGTGTTTTTGCCAAGGCCGTGAACTGCATAAAAATGACCGAGGATAAGGACTATCTGCAGCATGTTACCGAGCCC
TGCGGAGAGTGTGAAAGTTGCAGGGATTTTGAAGCGGGAACCAGCTTGAATATTGCTGAATTCGATGCGGCCTCAAACAA
CAGCGTTGATGATATTCGACTCCTCAGGGAGAATGTTCGTTATGGCCCGCAGAAAGGACGTTACAGGGTGTATATCATTG
ATGAGGTGCATATGCTTTCCATTGCGGCATTCAATGCTTTTCTCAAAACACTCGAAGAGCCTCCTCCGCATGCGATATTT
ATTTTTGCTACAACTGAACTGCATAAAATTCCGGCAACCATCGCTTCCCGTTGTCAGCGTTTCAATTTCAAGCGGATACC
GCTGAACGCTATTGAGGCGCAGCTTCTGCAAATTTGCGTAGCCGAGCAGATTGCTGTTGAGGCCGACGCGCTTCAGCTTA
TAGGAAGAAAAGCTCAGGGGTCAATGCGTGACGCACAAAGCATTCTTGATCAGGTAATCGCTTTTTCCGTTGATGCCGAG
CTGGGCGACGGGATCAGTTATGCAAAGGTTGCTGAATTATTGAACTATATCGATGATGAGCATTTTTTCGCGGTAACCGA
TGCGGTTGCTGATCAGGATCCGGTGAAAATGATCGACGTTGCGCAGTTCGTTTTGCAGAACGGTTATGATGAGCAGGATT
TTCTTGAGAAGCTGATCGAACATATGAGAAACATTCTGATGGTGCATAACCTGCATTCCACCCGTCTTGTCGAAAGGCCC
GATCCTGTTCGGGAGCGCTACCTGCGCGATGCAGCCCGTTTTTCTCCTTTGAGCATCATGCAGATGACCGAGTTTCTTCT
GCAGACACAGAAGGAGCTGAAATTTCAGTTTGAATACCAGTTTCGTTTTGAACTTGCCTTGCTCAGGCTTCTGGATTTTA
CCGGACAGGCCCCCTTATCAGTTGCAGCTCCTGGTGAAACCGCTCAAAAAAAAAAATCTCTCCTGAACGAGTAG

Upstream 100 bases:

>100_bases
ATATTGCCAGAGAGTATCGGTCATAATGTTACAGCAGGGATAAAAAGCGCAATGACTATTCCGCTTGCTACCGTGTTGCA
GGATAAAATCTATTGAAGTC

Downstream 100 bases:

>100_bases
TGCAGCCGGTACTCTCCGCGCCGACTCAAAAGCAGAAGGTCGCTGACCGACCAGCCACACAGACAGAGGAAATCGATCTT
GCCGGCTGGCAGAAAAAATT

Product: DNA polymerase III, subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSYQVIARKYRPKKFADITAQEHITRTIQNSLRMGRLGHGYIFSGLRGVGKTTAARVFAKAVNCIKMTEDKDYLQHVTEP
CGECESCRDFEAGTSLNIAEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIF
IFATTELHKIPATIASRCQRFNFKRIPLNAIEAQLLQICVAEQIAVEADALQLIGRKAQGSMRDAQSILDQVIAFSVDAE
LGDGISYAKVAELLNYIDDEHFFAVTDAVADQDPVKMIDVAQFVLQNGYDEQDFLEKLIEHMRNILMVHNLHSTRLVERP
DPVRERYLRDAARFSPLSIMQMTEFLLQTQKELKFQFEYQFRFELALLRLLDFTGQAPLSVAAPGETAQKKKSLLNE

Sequences:

>Translated_397_residues
MSYQVIARKYRPKKFADITAQEHITRTIQNSLRMGRLGHGYIFSGLRGVGKTTAARVFAKAVNCIKMTEDKDYLQHVTEP
CGECESCRDFEAGTSLNIAEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIF
IFATTELHKIPATIASRCQRFNFKRIPLNAIEAQLLQICVAEQIAVEADALQLIGRKAQGSMRDAQSILDQVIAFSVDAE
LGDGISYAKVAELLNYIDDEHFFAVTDAVADQDPVKMIDVAQFVLQNGYDEQDFLEKLIEHMRNILMVHNLHSTRLVERP
DPVRERYLRDAARFSPLSIMQMTEFLLQTQKELKFQFEYQFRFELALLRLLDFTGQAPLSVAAPGETAQKKKSLLNE
>Mature_396_residues
SYQVIARKYRPKKFADITAQEHITRTIQNSLRMGRLGHGYIFSGLRGVGKTTAARVFAKAVNCIKMTEDKDYLQHVTEPC
GECESCRDFEAGTSLNIAEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFI
FATTELHKIPATIASRCQRFNFKRIPLNAIEAQLLQICVAEQIAVEADALQLIGRKAQGSMRDAQSILDQVIAFSVDAEL
GDGISYAKVAELLNYIDDEHFFAVTDAVADQDPVKMIDVAQFVLQNGYDEQDFLEKLIEHMRNILMVHNLHSTRLVERPD
PVRERYLRDAARFSPLSIMQMTEFLLQTQKELKFQFEYQFRFELALLRLLDFTGQAPLSVAAPGETAQKKKSLLNE

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=384, Percent_Identity=40.625, Blast_Score=276, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6324478, Length=232, Percent_Identity=26.7241379310345, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324039, Length=224, Percent_Identity=23.2142857142857, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322528, Length=308, Percent_Identity=23.7012987012987, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 45116; Mature: 44985

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQVIARKYRPKKFADITAQEHITRTIQNSLRMGRLGHGYIFSGLRGVGKTTAARVFAK
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHH
AVNCIKMTEDKDYLQHVTEPCGECESCRDFEAGTSLNIAEFDAASNNSVDDIRLLRENVR
HHHHHHCCCCHHHHHHHHHHHCCCHHCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHC
YGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQR
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHH
FNFKRIPLNAIEAQLLQICVAEQIAVEADALQLIGRKAQGSMRDAQSILDQVIAFSVDAE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCH
LGDGISYAKVAELLNYIDDEHFFAVTDAVADQDPVKMIDVAQFVLQNGYDEQDFLEKLIE
HCCCCCHHHHHHHHHHHCCCCEEEEHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
HMRNILMVHNLHSTRLVERPDPVRERYLRDAARFSPLSIMQMTEFLLQTQKELKFQFEYQ
HHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCEEEEEEH
FRFELALLRLLDFTGQAPLSVAAPGETAQKKKSLLNE
HHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCC
>Mature Secondary Structure 
SYQVIARKYRPKKFADITAQEHITRTIQNSLRMGRLGHGYIFSGLRGVGKTTAARVFAK
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHH
AVNCIKMTEDKDYLQHVTEPCGECESCRDFEAGTSLNIAEFDAASNNSVDDIRLLRENVR
HHHHHHCCCCHHHHHHHHHHHCCCHHCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHC
YGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQR
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHH
FNFKRIPLNAIEAQLLQICVAEQIAVEADALQLIGRKAQGSMRDAQSILDQVIAFSVDAE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCH
LGDGISYAKVAELLNYIDDEHFFAVTDAVADQDPVKMIDVAQFVLQNGYDEQDFLEKLIE
HCCCCCHHHHHHHHHHHCCCCEEEEHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
HMRNILMVHNLHSTRLVERPDPVRERYLRDAARFSPLSIMQMTEFLLQTQKELKFQFEYQ
HHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCEEEEEEH
FRFELALLRLLDFTGQAPLSVAAPGETAQKKKSLLNE
HHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]