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The map label for this gene is fucO [H]

Identifier: 119357315

GI number: 119357315

Start: 1720791

End: 1721921

Strand: Reverse

Name: fucO [H]

Synonym: Cpha266_1513

Alternate gene names: 119357315

Gene position: 1721921-1720791 (Counterclockwise)

Preceding gene: 119357316

Following gene: 119357314

Centisome position: 54.94

GC content: 50.49

Gene sequence:

>1131_bases
ATGAATTTCTTTTTATCGACGGACATTATTATCGGAGTCAACGAAGCCATGCGGCTGATTGACAGCATCAGACAGCTTGC
GATATCCAGACCCGGAATCATCTACGACGCAAATCTTGCCGGGAGTTTTTACTTTCAGGATGTTCTGAAAAATATCACCT
CCGCGTTTGAAAACTGCGTCCTGTACTGCAACGATTTTAATGGCGAGCCAACGTATGCCCATCTTGAAAAGACATCGGAG
TTTTTCCGGCAGCATAAGCCTGACGGTCTTGTCGCAATAGGCGGAGGGAGCACGCTCGATCTCGGCAAAGGCGTTGCTCT
TTTGATGACCAATCCGGTTCCCGCGCTCTCGCTCAAAGGTTTTCCCGAAAACGTCAATGATCCGGTACCGCTCATCACGG
TTCCATCGATTCTCGGAAGCGGAGCGGAAGTGAGCTATAATGCGGTGTTTATCGACGAGAACGAAGGACGGAAACTCGGC
ATCAACAGTCGTCGCAATTTCCCGAAAAAGTCCGTGATCGATCCTCTTCTTTCCATGACAGCTCCAATGGAAAGCGTTAT
TTCAACGGCAATGGACAGTCTCGTTCACTGTATTGACAGTTTCGGTTCGATCAGGCACTCTCCGCTCAGCAGAATTTTTT
CTGTTGAAGGGTTTCAGCGAACCTTCTACGCGCTTCAGCAAGGGCAGCTTGACCGGGCTGAAGCGCGCCTTGACCTTGCT
CTTGGGAGTATTTGCGGAACGGTTGCTCTCATGAACTCGGGAGACGGGCCGACCAATGGATTTGCCTACTATCTCGGCGT
GAAGCAAAAGGTGCCGCATGGTCTTGCGGGAGCGATTTTTCTGAAAGAGGTCATGCGTTACAATTTCGATCACGGCTACG
ATAAATATGCGCTGCTTAACCCCATGCGCAGCTCACCATCCCCGAAAGATGCAACGCAGGAGCTGCTTGAAGAGATGGAT
GAGCTCTACCGGCAGCTTGACATCCCCAATCTTGTGCCATACGGGTACGCAAAGGGCAATGTCGCTGAACTTGCAAAGAA
TGCATCGGAAGCCCTCAAAGGATCGTTTGCCGGAAACCCGGTTGCGTTTACCGAGGAGTCGGCACGTTACATAATCAATA
ATCTAACCTGA

Upstream 100 bases:

>100_bases
TTGATACGATTGATGAGATAGATTTAGTTGAATTTTATATGTTCAAAAAAAATCTGGCAAAAAAGAGTGCCGTTTGAACA
AACCACCAGAACGCTTACCT

Downstream 100 bases:

>100_bases
TAACTACACAACAATAATGGCAGGAGCAGAACTCATAGGAAAGGAAGAGCTGGCCGAAATTCTGGAACTTTTCAGCGGCG
AAAAGGTAAACCTCTATCGC

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: Propanediol oxidoreductase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MNFFLSTDIIIGVNEAMRLIDSIRQLAISRPGIIYDANLAGSFYFQDVLKNITSAFENCVLYCNDFNGEPTYAHLEKTSE
FFRQHKPDGLVAIGGGSTLDLGKGVALLMTNPVPALSLKGFPENVNDPVPLITVPSILGSGAEVSYNAVFIDENEGRKLG
INSRRNFPKKSVIDPLLSMTAPMESVISTAMDSLVHCIDSFGSIRHSPLSRIFSVEGFQRTFYALQQGQLDRAEARLDLA
LGSICGTVALMNSGDGPTNGFAYYLGVKQKVPHGLAGAIFLKEVMRYNFDHGYDKYALLNPMRSSPSPKDATQELLEEMD
ELYRQLDIPNLVPYGYAKGNVAELAKNASEALKGSFAGNPVAFTEESARYIINNLT

Sequences:

>Translated_376_residues
MNFFLSTDIIIGVNEAMRLIDSIRQLAISRPGIIYDANLAGSFYFQDVLKNITSAFENCVLYCNDFNGEPTYAHLEKTSE
FFRQHKPDGLVAIGGGSTLDLGKGVALLMTNPVPALSLKGFPENVNDPVPLITVPSILGSGAEVSYNAVFIDENEGRKLG
INSRRNFPKKSVIDPLLSMTAPMESVISTAMDSLVHCIDSFGSIRHSPLSRIFSVEGFQRTFYALQQGQLDRAEARLDLA
LGSICGTVALMNSGDGPTNGFAYYLGVKQKVPHGLAGAIFLKEVMRYNFDHGYDKYALLNPMRSSPSPKDATQELLEEMD
ELYRQLDIPNLVPYGYAKGNVAELAKNASEALKGSFAGNPVAFTEESARYIINNLT
>Mature_376_residues
MNFFLSTDIIIGVNEAMRLIDSIRQLAISRPGIIYDANLAGSFYFQDVLKNITSAFENCVLYCNDFNGEPTYAHLEKTSE
FFRQHKPDGLVAIGGGSTLDLGKGVALLMTNPVPALSLKGFPENVNDPVPLITVPSILGSGAEVSYNAVFIDENEGRKLG
INSRRNFPKKSVIDPLLSMTAPMESVISTAMDSLVHCIDSFGSIRHSPLSRIFSVEGFQRTFYALQQGQLDRAEARLDLA
LGSICGTVALMNSGDGPTNGFAYYLGVKQKVPHGLAGAIFLKEVMRYNFDHGYDKYALLNPMRSSPSPKDATQELLEEMD
ELYRQLDIPNLVPYGYAKGNVAELAKNASEALKGSFAGNPVAFTEESARYIINNLT

Specific function: Fucose metabolism; fourth step. [C]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=325, Percent_Identity=26.1538461538462, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789163, Length=358, Percent_Identity=26.8156424581006, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082107, Length=308, Percent_Identity=24.3506493506494, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI48994951, Length=378, Percent_Identity=23.8095238095238, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787493, Length=302, Percent_Identity=23.841059602649, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17537053, Length=405, Percent_Identity=23.9506172839506, Blast_Score=88, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6321181, Length=307, Percent_Identity=24.7557003257329, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR013460 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.77 [H]

Molecular weight: Translated: 41103; Mature: 41103

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFFLSTDIIIGVNEAMRLIDSIRQLAISRPGIIYDANLAGSFYFQDVLKNITSAFENCV
CCEEEECCEEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCEE
LYCNDFNGEPTYAHLEKTSEFFRQHKPDGLVAIGGGSTLDLGKGVALLMTNPVPALSLKG
EEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEECCCCEEEEEECCCCCCEECC
FPENVNDPVPLITVPSILGSGAEVSYNAVFIDENEGRKLGINSRRNFPKKSVIDPLLSMT
CCCCCCCCCCEEEHHHHHCCCCCEEEEEEEEECCCCCEECCCCCCCCCHHHHHHHHHHHH
APMESVISTAMDSLVHCIDSFGSIRHSPLSRIFSVEGFQRTFYALQQGQLDRAEARLDLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHH
LGSICGTVALMNSGDGPTNGFAYYLGVKQKVPHGLAGAIFLKEVMRYNFDHGYDKYALLN
HHHHHHHHHEEECCCCCCCCEEEEEECHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHC
PMRSSPSPKDATQELLEEMDELYRQLDIPNLVPYGYAKGNVAELAKNASEALKGSFAGNP
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
VAFTEESARYIINNLT
EEECCCHHHHHHHCCC
>Mature Secondary Structure
MNFFLSTDIIIGVNEAMRLIDSIRQLAISRPGIIYDANLAGSFYFQDVLKNITSAFENCV
CCEEEECCEEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCEE
LYCNDFNGEPTYAHLEKTSEFFRQHKPDGLVAIGGGSTLDLGKGVALLMTNPVPALSLKG
EEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEECCCCEEEEEECCCCCCEECC
FPENVNDPVPLITVPSILGSGAEVSYNAVFIDENEGRKLGINSRRNFPKKSVIDPLLSMT
CCCCCCCCCCEEEHHHHHCCCCCEEEEEEEEECCCCCEECCCCCCCCCHHHHHHHHHHHH
APMESVISTAMDSLVHCIDSFGSIRHSPLSRIFSVEGFQRTFYALQQGQLDRAEARLDLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHH
LGSICGTVALMNSGDGPTNGFAYYLGVKQKVPHGLAGAIFLKEVMRYNFDHGYDKYALLN
HHHHHHHHHEEECCCCCCCCEEEEEECHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHC
PMRSSPSPKDATQELLEEMDELYRQLDIPNLVPYGYAKGNVAELAKNASEALKGSFAGNP
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
VAFTEESARYIINNLT
EEECCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]