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The map label for this gene is yfnA [H]

Identifier: 119357312

GI number: 119357312

Start: 1713892

End: 1715379

Strand: Reverse

Name: yfnA [H]

Synonym: Cpha266_1510

Alternate gene names: 119357312

Gene position: 1715379-1713892 (Counterclockwise)

Preceding gene: 119357313

Following gene: 119357311

Centisome position: 54.74

GC content: 53.49

Gene sequence:

>1488_bases
GTGAAACATCTGTTCAGAAAAAAAACGCTTGCCGTTCTTCTCGAAGAGGTTCAGGGTGAAAACCGGCTGAAAAGGATTCT
CGGACCGGTAGCCCTCACCAGTCTTGGGGTCGGCGCGATTATCGGCACCGGCATTTTTGTGCTGATCGGCGTTGCCGCTC
ATGATAAAGCCGGTCCTGCCGTTACCCTTTCGTTTGCCATAGCCGGTCTTGCCTGTATTTTTGCCGCCCTCTGCTACGCC
GAGTTTGCATCGATGGCGCCGGTGGCCGGTTCAGCCTATACTTACGCCTATGCCACGCTCGGCGAACTGTTCGCATGGAT
TATCGGCTGGGATCTTATTCTTGAGTATGCCGTTGCATCGGCAACGGTAGCGCACGGCTGGTCGCACTATTTTCAGGACT
TTATCGGAATATTCGGGCTTGGGGTGCCTGAACTCCTGTCGCGGGCACCGCTCGATTTCGATCCTGCCACCGGAATGCTC
ACAGGAACCGGCGCACTGTTCGATCTTCCGGCAGTGGTTATTACTGCCATTGTGACGACGGTGCTGGTTAAGGGAATCAG
GGAGAGTTCCGGGTTCAATACGGCCATGGTGGTGATCAAGGTGGCTATTGTTCTTCTTGTGATTGTTCTCGGCGCCATGT
ATGTCAACCCGGCCAACTGGCAGCCCTTTGCTCCCTTCGGGTATTCCGGCTTCAGCATTTTCGGAAGAACCGTGCTTGGA
GAGGTCGGGGCAGGAGGAGCTCCCGTTGGGGTGCTTGCCGGTGCGGCCATGATTTTCTTTGCCTATATAGGATTCGATTC
CATTTCAACCCACGCAGAAGAGGCAATCAACCCGCAGCGCGATGTGCCGATTGCCCTCATCGCATCATTGGTTATTTGTA
CCATACTCTACATTGCCGTTGCTACCGTGATAACCGGTATGGTTCCTTACGATCAGATCAATATTGATGCGCCGGTCTCC
AACGCTTTCAAGCAGGTTGGTATCGGATGGGCTCAGTTTCTCGTCTCTCTGGGAGCGATAACCGGCATAACCTCGGTGCT
GCTGGTCATGATGCTCAGTCAGCCACGCATTTTTCTTGCCATGGCTCGAGACGGACTCTTACCGAAAAACGTCTTTGGCG
CCATTCACGAAAAGTACAGGACACCCTGGAAATCAACCATTCTTACCGGCGTTTTCGTGTCGATTCTCGCTGCATTTCTT
CCACTGCGCCTCCTTGCCGAACTGGTCAATATCGGCACGCTCTTTGCATTTGTCGTTGTCTGTGCAGCGGTGCTTATCAT
GCGCAAAAAACATCCTGAAGCTCATCGTCCTTTCCGCGCGCCGCTTGTTCCCTTTGTTCCTCTTGCCGGTATATTCACCT
GTCTTCTTCTGATGTTTTCACTTCCTGCCGAAAACTGGGTACGGCTTATCGCATGGCTTCTGATCGGCCTGTGCATCTAC
TTCTTTTACGGAAGGCGCCACAGCGAGCTGCGACGCCAGCAGCAGTAA

Upstream 100 bases:

>100_bases
TGTTTTTTAGCGCTTCCCGTTGGGGTAAGCGTATAAAAATATGTTAAATTAGCATGTTTTTGCCTTGACGGTTCTCTCTA
CACCTATCCAGAAACTGCCC

Downstream 100 bases:

>100_bases
TTGCACAATCCTCCCGCTTTTGCTCCGCCGCTTTCGAATTATCTGTGCAGATAGTCAAAGCGGCGGAGATAAAACTCCAA
ATCATACGAAAGGCTCAGGA

Product: amino acid permease-associated region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MKHLFRKKTLAVLLEEVQGENRLKRILGPVALTSLGVGAIIGTGIFVLIGVAAHDKAGPAVTLSFAIAGLACIFAALCYA
EFASMAPVAGSAYTYAYATLGELFAWIIGWDLILEYAVASATVAHGWSHYFQDFIGIFGLGVPELLSRAPLDFDPATGML
TGTGALFDLPAVVITAIVTTVLVKGIRESSGFNTAMVVIKVAIVLLVIVLGAMYVNPANWQPFAPFGYSGFSIFGRTVLG
EVGAGGAPVGVLAGAAMIFFAYIGFDSISTHAEEAINPQRDVPIALIASLVICTILYIAVATVITGMVPYDQINIDAPVS
NAFKQVGIGWAQFLVSLGAITGITSVLLVMMLSQPRIFLAMARDGLLPKNVFGAIHEKYRTPWKSTILTGVFVSILAAFL
PLRLLAELVNIGTLFAFVVVCAAVLIMRKKHPEAHRPFRAPLVPFVPLAGIFTCLLLMFSLPAENWVRLIAWLLIGLCIY
FFYGRRHSELRRQQQ

Sequences:

>Translated_495_residues
MKHLFRKKTLAVLLEEVQGENRLKRILGPVALTSLGVGAIIGTGIFVLIGVAAHDKAGPAVTLSFAIAGLACIFAALCYA
EFASMAPVAGSAYTYAYATLGELFAWIIGWDLILEYAVASATVAHGWSHYFQDFIGIFGLGVPELLSRAPLDFDPATGML
TGTGALFDLPAVVITAIVTTVLVKGIRESSGFNTAMVVIKVAIVLLVIVLGAMYVNPANWQPFAPFGYSGFSIFGRTVLG
EVGAGGAPVGVLAGAAMIFFAYIGFDSISTHAEEAINPQRDVPIALIASLVICTILYIAVATVITGMVPYDQINIDAPVS
NAFKQVGIGWAQFLVSLGAITGITSVLLVMMLSQPRIFLAMARDGLLPKNVFGAIHEKYRTPWKSTILTGVFVSILAAFL
PLRLLAELVNIGTLFAFVVVCAAVLIMRKKHPEAHRPFRAPLVPFVPLAGIFTCLLLMFSLPAENWVRLIAWLLIGLCIY
FFYGRRHSELRRQQQ
>Mature_495_residues
MKHLFRKKTLAVLLEEVQGENRLKRILGPVALTSLGVGAIIGTGIFVLIGVAAHDKAGPAVTLSFAIAGLACIFAALCYA
EFASMAPVAGSAYTYAYATLGELFAWIIGWDLILEYAVASATVAHGWSHYFQDFIGIFGLGVPELLSRAPLDFDPATGML
TGTGALFDLPAVVITAIVTTVLVKGIRESSGFNTAMVVIKVAIVLLVIVLGAMYVNPANWQPFAPFGYSGFSIFGRTVLG
EVGAGGAPVGVLAGAAMIFFAYIGFDSISTHAEEAINPQRDVPIALIASLVICTILYIAVATVITGMVPYDQINIDAPVS
NAFKQVGIGWAQFLVSLGAITGITSVLLVMMLSQPRIFLAMARDGLLPKNVFGAIHEKYRTPWKSTILTGVFVSILAAFL
PLRLLAELVNIGTLFAFVVVCAAVLIMRKKHPEAHRPFRAPLVPFVPLAGIFTCLLLMFSLPAENWVRLIAWLLIGLCIY
FFYGRRHSELRRQQQ

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=442, Percent_Identity=37.10407239819, Blast_Score=266, Evalue=4e-71,
Organism=Homo sapiens, GI114326544, Length=449, Percent_Identity=34.7438752783964, Blast_Score=254, Evalue=2e-67,
Organism=Homo sapiens, GI114326550, Length=449, Percent_Identity=34.7438752783964, Blast_Score=254, Evalue=2e-67,
Organism=Homo sapiens, GI258645169, Length=440, Percent_Identity=36.8181818181818, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI258614003, Length=440, Percent_Identity=36.1363636363636, Blast_Score=252, Evalue=6e-67,
Organism=Homo sapiens, GI258614005, Length=440, Percent_Identity=36.1363636363636, Blast_Score=252, Evalue=6e-67,
Organism=Homo sapiens, GI181337167, Length=445, Percent_Identity=36.4044943820225, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI110347453, Length=419, Percent_Identity=36.9928400954654, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI33286428, Length=469, Percent_Identity=25.5863539445629, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI7657683, Length=395, Percent_Identity=22.7848101265823, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI187423910, Length=483, Percent_Identity=21.1180124223602, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI7657591, Length=483, Percent_Identity=21.1180124223602, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI71979932, Length=237, Percent_Identity=27.0042194092827, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI87082250, Length=489, Percent_Identity=27.8118609406953, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI87081869, Length=487, Percent_Identity=22.9979466119097, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87082023, Length=470, Percent_Identity=25.3191489361702, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081708, Length=503, Percent_Identity=22.0675944333996, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87081915, Length=447, Percent_Identity=24.6085011185682, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786302, Length=433, Percent_Identity=25.8660508083141, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786602, Length=502, Percent_Identity=22.9083665338645, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI48994972, Length=508, Percent_Identity=25.1968503937008, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788480, Length=518, Percent_Identity=22.007722007722, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367353, Length=187, Percent_Identity=29.9465240641711, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=435, Percent_Identity=35.1724137931034, Blast_Score=252, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI17533459, Length=431, Percent_Identity=34.8027842227378, Blast_Score=231, Evalue=7e-61,
Organism=Caenorhabditis elegans, GI17531343, Length=435, Percent_Identity=33.5632183908046, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17537453, Length=392, Percent_Identity=20.1530612244898, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17540018, Length=214, Percent_Identity=27.1028037383178, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221512776, Length=430, Percent_Identity=40, Blast_Score=288, Evalue=4e-78,
Organism=Drosophila melanogaster, GI24666159, Length=430, Percent_Identity=40, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24668806, Length=453, Percent_Identity=38.4105960264901, Blast_Score=282, Evalue=4e-76,
Organism=Drosophila melanogaster, GI21356285, Length=453, Percent_Identity=38.4105960264901, Blast_Score=282, Evalue=4e-76,
Organism=Drosophila melanogaster, GI24668802, Length=453, Percent_Identity=38.4105960264901, Blast_Score=282, Evalue=4e-76,
Organism=Drosophila melanogaster, GI24667468, Length=435, Percent_Identity=36.3218390804598, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI281366235, Length=427, Percent_Identity=35.3629976580796, Blast_Score=229, Evalue=5e-60,
Organism=Drosophila melanogaster, GI116007820, Length=427, Percent_Identity=35.3629976580796, Blast_Score=229, Evalue=5e-60,
Organism=Drosophila melanogaster, GI116007818, Length=428, Percent_Identity=35.5140186915888, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI85725152, Length=428, Percent_Identity=35.5140186915888, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI161077963, Length=453, Percent_Identity=33.7748344370861, Blast_Score=215, Evalue=6e-56,
Organism=Drosophila melanogaster, GI21357367, Length=444, Percent_Identity=22.7477477477477, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221331183, Length=482, Percent_Identity=23.2365145228216, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17647653, Length=482, Percent_Identity=23.2365145228216, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24664379, Length=482, Percent_Identity=23.2365145228216, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53152; Mature: 53152

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCHHHHHHHCCC
>Mature Secondary Structure
MKHLFRKKTLAVLLEEVQGENRLKRILGPVALTSLGVGAIIGTGIFVLIGVAAHDKAGPA
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
VTLSFAIAGLACIFAALCYAEFASMAPVAGSAYTYAYATLGELFAWIIGWDLILEYAVAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATVAHGWSHYFQDFIGIFGLGVPELLSRAPLDFDPATGMLTGTGALFDLPAVVITAIVTT
HHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHH
VLVKGIRESSGFNTAMVVIKVAIVLLVIVLGAMYVNPANWQPFAPFGYSGFSIFGRTVLG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
EVGAGGAPVGVLAGAAMIFFAYIGFDSISTHAEEAINPQRDVPIALIASLVICTILYIAV
HCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
ATVITGMVPYDQINIDAPVSNAFKQVGIGWAQFLVSLGAITGITSVLLVMMLSQPRIFLA
HHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
MARDGLLPKNVFGAIHEKYRTPWKSTILTGVFVSILAAFLPLRLLAELVNIGTLFAFVVV
EHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CAAVLIMRKKHPEAHRPFRAPLVPFVPLAGIFTCLLLMFSLPAENWVRLIAWLLIGLCIY
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FFYGRRHSELRRQQQ
HHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]