Click here to switch to the map view.

The map label for this gene is prc [H]

Identifier: 119357139

GI number: 119357139

Start: 1521787

End: 1523871

Strand: Reverse

Name: prc [H]

Synonym: Cpha266_1328

Alternate gene names: 119357139

Gene position: 1523871-1521787 (Counterclockwise)

Preceding gene: 119357141

Following gene: 119357137

Centisome position: 48.63

GC content: 48.59

Gene sequence:

>2085_bases
ATGGCTCGCCTCGCATCAATATTGTCAAGAAACGGATTTCTTGTTCTCATTCTTTCTTTTCTCTTTTCCTGCCCGGCACT
TGCAGTAATCAAGAAACCGGCTGCTGCCGGCGCCAATGCGAAAGCGACTTCCTCTGCAGCGGTTACGCTTAAAGCCTCGC
CTGTCCAGGATGAAGCCACAGGATATATCGCCCAGTATCTGATGCAGAACCATTACAGAAAGGTGGCGGTTAACGACTCG
CTTTCAAGGGAGATTTTCAACCGATACCTTGAGCATCTCGATGCAGGCAAGAGTTATTTTATTGCCAGTGAGGTCGAGAG
CATGAGACAGTATTATGGTACGCGTTTCGACAATGAGTTTCTGACGGGAAAAAGCACATCCGGTTTTGCTGTCTACAATT
TCTTTTTGAAAAGAGCCAGGGAGAAAATGCGTTTCATGAAAGCGGTTGCCGATACCGCTCAATTTGATTTCTCCAGACCC
GAAACGCTGAATCTCGATCGCAAGAGCGATACCTGGCCGCTTGACCGTAATGAACTCTATGCGATCTGGAGAAAAGAGCT
GAAATATCAGTGGCTTAATCTCAAATACGGGGCCGAAAAAGAGTCATCGATACGTACAGCTCTTTCAAAACGATACGCCA
ACCGGTTGAAACTGCTTAACCTTCAGAAAAGCGACGATGCTTTTCAGGCATACATGTTTGCGGTTACCACCTCCTTTGAT
CCGCATACAAACTATTTTTCGCCCGATGAATTCGAGAACTTCCAGATCGATTTAAGTCGCTCACTTGAAGGCATCGGAGC
CAAATTGCAGATGGAAAGTGATTTTACGGTTGTTAACGAGATCATTCCCGGGGGGCCGGCCTTTAAAAGCTCTCTTTTGA
AAAAATCCGACAGGATTATCGGCGTTGGACAGGGGAGAACTTCTGAAATTGTGGATGTGACAGGATGGCGTCTCAATGAT
GTTGTCAAAAAGATCCGCGGACCGAAAGGCACCTATGTACGGTTGAAAATCCTTCCGGCAAGCCAGGCGGGGAGAGGCCC
GGCAAAGATCGTTCAGCTTGTTCGCGATAAAATCAATCTTGACGAACAGGCCGCGCAAAAGAGAATCATGACGCTCAATA
ACGAAAAAATCGGCGTGATTACCATTCCGTCCTTTTATCTTGATTTTGAAGCGCAGAAACGCCATGCCGGCAGGTATAAC
AGTACAAGTCGGGATGTGGCAAGGATAATCGGCGAGCTCAAGGCACAAAAAGTTCAGGGTATCATTATCGATCTCAGGGA
TAACGGAGGGGGATCGCTCGAGGAGGCTGTCAATGTGACCGGTCTGTTTATTTCCAATGGACCGGTCGTTCAGGTCAGCA
ACTCCTCAGGTGGTAAAATGGTACTCAGGGATGAAGACAACCGGGTGTTGTTTGACGGCCCGATTGCTGTTCTGGTTAAC
CGGTACAGCGCTTCGGCATCTGAAATTTTTGCTGCGGCAATTCAGGATTACGGCAGGGGAGTCATCATCGGAGAGCGAAC
CTTTGGCAAAGGAACAGTCCAGAGCATTGTAAAGCTCACCCGTCCATTCAGCTTTTTTGCCAACAAGGCCGAACTTGGCC
AGATGAAACTGACCATCGCCAAATTTTATCGGATATCCGGTGAAAGCACCCAGCACAAGGGCGTTGTGCCGGACATCGGC
ATCTCGTCGCTGATCGACACCTCATCTGTCGGAGAAGATACCTATACGAGCAGTTTGCCCTGGAGCACTATTTCAAAAGC
ACTCTATACTCCTCTGGGCACAACGGGTAAAATCAGTACGGGACGTCTGCTGCAGCAGTACAAGGCTCGCTCATCCAGCC
AGAAGGTTTACCAGGATTACATGCGCGACCTTGCTTCTCTCAATGCCATTCGCAAAAAGAAGGTCGTTTCCCTTAACGAA
AAAACATTCAAGACCGAAAGCGAGCGCCTGAAGCAGATCGAGCAGTCATGGGCGGTTGAGCAGGATGGCGTTAAAAATCC
TTCAAAGGATTTCATGCTGAACAGATCTGCCGAAATCATGTCCGACATGATCCCGCCTGACAGCGGATCGCAGGCATTGA
AGTAA

Upstream 100 bases:

>100_bases
TTTAGCCGGTTTATGAAAAAACAGTAAATTGATTTATAGAGAATTGCAATATAATAGTTTTCCGGTTCAAGAACACCCAA
GCTTTCACAGTTCCTTAATT

Downstream 100 bases:

>100_bases
GGAAAAACCTGCAAGGCATCGTAAATCCCGTTATCCCGGCACTCGATATCGGGTCGTTTTCCTGTGCCGCATATCGCTAC
CTGTTTTCCTGCATCTGCGC

Product: C-terminal processing peptidase-1

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 694; Mature: 693

Protein sequence:

>694_residues
MARLASILSRNGFLVLILSFLFSCPALAVIKKPAAAGANAKATSSAAVTLKASPVQDEATGYIAQYLMQNHYRKVAVNDS
LSREIFNRYLEHLDAGKSYFIASEVESMRQYYGTRFDNEFLTGKSTSGFAVYNFFLKRAREKMRFMKAVADTAQFDFSRP
ETLNLDRKSDTWPLDRNELYAIWRKELKYQWLNLKYGAEKESSIRTALSKRYANRLKLLNLQKSDDAFQAYMFAVTTSFD
PHTNYFSPDEFENFQIDLSRSLEGIGAKLQMESDFTVVNEIIPGGPAFKSSLLKKSDRIIGVGQGRTSEIVDVTGWRLND
VVKKIRGPKGTYVRLKILPASQAGRGPAKIVQLVRDKINLDEQAAQKRIMTLNNEKIGVITIPSFYLDFEAQKRHAGRYN
STSRDVARIIGELKAQKVQGIIIDLRDNGGGSLEEAVNVTGLFISNGPVVQVSNSSGGKMVLRDEDNRVLFDGPIAVLVN
RYSASASEIFAAAIQDYGRGVIIGERTFGKGTVQSIVKLTRPFSFFANKAELGQMKLTIAKFYRISGESTQHKGVVPDIG
ISSLIDTSSVGEDTYTSSLPWSTISKALYTPLGTTGKISTGRLLQQYKARSSSQKVYQDYMRDLASLNAIRKKKVVSLNE
KTFKTESERLKQIEQSWAVEQDGVKNPSKDFMLNRSAEIMSDMIPPDSGSQALK

Sequences:

>Translated_694_residues
MARLASILSRNGFLVLILSFLFSCPALAVIKKPAAAGANAKATSSAAVTLKASPVQDEATGYIAQYLMQNHYRKVAVNDS
LSREIFNRYLEHLDAGKSYFIASEVESMRQYYGTRFDNEFLTGKSTSGFAVYNFFLKRAREKMRFMKAVADTAQFDFSRP
ETLNLDRKSDTWPLDRNELYAIWRKELKYQWLNLKYGAEKESSIRTALSKRYANRLKLLNLQKSDDAFQAYMFAVTTSFD
PHTNYFSPDEFENFQIDLSRSLEGIGAKLQMESDFTVVNEIIPGGPAFKSSLLKKSDRIIGVGQGRTSEIVDVTGWRLND
VVKKIRGPKGTYVRLKILPASQAGRGPAKIVQLVRDKINLDEQAAQKRIMTLNNEKIGVITIPSFYLDFEAQKRHAGRYN
STSRDVARIIGELKAQKVQGIIIDLRDNGGGSLEEAVNVTGLFISNGPVVQVSNSSGGKMVLRDEDNRVLFDGPIAVLVN
RYSASASEIFAAAIQDYGRGVIIGERTFGKGTVQSIVKLTRPFSFFANKAELGQMKLTIAKFYRISGESTQHKGVVPDIG
ISSLIDTSSVGEDTYTSSLPWSTISKALYTPLGTTGKISTGRLLQQYKARSSSQKVYQDYMRDLASLNAIRKKKVVSLNE
KTFKTESERLKQIEQSWAVEQDGVKNPSKDFMLNRSAEIMSDMIPPDSGSQALK
>Mature_693_residues
ARLASILSRNGFLVLILSFLFSCPALAVIKKPAAAGANAKATSSAAVTLKASPVQDEATGYIAQYLMQNHYRKVAVNDSL
SREIFNRYLEHLDAGKSYFIASEVESMRQYYGTRFDNEFLTGKSTSGFAVYNFFLKRAREKMRFMKAVADTAQFDFSRPE
TLNLDRKSDTWPLDRNELYAIWRKELKYQWLNLKYGAEKESSIRTALSKRYANRLKLLNLQKSDDAFQAYMFAVTTSFDP
HTNYFSPDEFENFQIDLSRSLEGIGAKLQMESDFTVVNEIIPGGPAFKSSLLKKSDRIIGVGQGRTSEIVDVTGWRLNDV
VKKIRGPKGTYVRLKILPASQAGRGPAKIVQLVRDKINLDEQAAQKRIMTLNNEKIGVITIPSFYLDFEAQKRHAGRYNS
TSRDVARIIGELKAQKVQGIIIDLRDNGGGSLEEAVNVTGLFISNGPVVQVSNSSGGKMVLRDEDNRVLFDGPIAVLVNR
YSASASEIFAAAIQDYGRGVIIGERTFGKGTVQSIVKLTRPFSFFANKAELGQMKLTIAKFYRISGESTQHKGVVPDIGI
SSLIDTSSVGEDTYTSSLPWSTISKALYTPLGTTGKISTGRLLQQYKARSSSQKVYQDYMRDLASLNAIRKKKVVSLNEK
TFKTESERLKQIEQSWAVEQDGVKNPSKDFMLNRSAEIMSDMIPPDSGSQALK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=595, Percent_Identity=40, Blast_Score=427, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 77364; Mature: 77233

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ ; PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLASILSRNGFLVLILSFLFSCPALAVIKKPAAAGANAKATSSAAVTLKASPVQDEAT
CCHHHHHHCCCCHHHHHHHHHHHCCCEEHHCCCCCCCCCCCCCCCEEEEEEECCCCHHHH
GYIAQYLMQNHYRKVAVNDSLSREIFNRYLEHLDAGKSYFIASEVESMRQYYGTRFDNEF
HHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCCE
LTGKSTSGFAVYNFFLKRAREKMRFMKAVADTAQFDFSRPETLNLDRKSDTWPLDRNELY
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCHHHH
AIWRKELKYQWLNLKYGAEKESSIRTALSKRYANRLKLLNLQKSDDAFQAYMFAVTTSFD
HHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHEEEEEEEECCC
PHTNYFSPDEFENFQIDLSRSLEGIGAKLQMESDFTVVNEIIPGGPAFKSSLLKKSDRII
CCCCCCCCCCCCCEEEEHHHHHCCCCCEEEECCCCHHHHHHCCCCHHHHHHHHHCCCCEE
GVGQGRTSEIVDVTGWRLNDVVKKIRGPKGTYVRLKILPASQAGRGPAKIVQLVRDKINL
EECCCCCCCEEEECCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCC
DEQAAQKRIMTLNNEKIGVITIPSFYLDFEAQKRHAGRYNSTSRDVARIIGELKAQKVQG
CHHHHHHHHEEECCCEEEEEECCCEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCE
IIIDLRDNGGGSLEEAVNVTGLFISNGPVVQVSNSSGGKMVLRDEDNRVLFDGPIAVLVN
EEEEEECCCCCCHHHHCCEEEEEECCCCEEEEECCCCCEEEEEECCCEEEECCCCEEEHH
RYSASASEIFAAAIQDYGRGVIIGERTFGKGTVQSIVKLTRPFSFFANKAELGQMKLTIA
HCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCHHHHCCHHHHCHHHEEHH
KFYRISGESTQHKGVVPDIGISSLIDTSSVGEDTYTSSLPWSTISKALYTPLGTTGKIST
HHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCH
GRLLQQYKARSSSQKVYQDYMRDLASLNAIRKKKVVSLNEKTFKTESERLKQIEQSWAVE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHCCHHHHHHHHHHHHCCC
QDGVKNPSKDFMLNRSAEIMSDMIPPDSGSQALK
CCCCCCCCHHHEECCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ARLASILSRNGFLVLILSFLFSCPALAVIKKPAAAGANAKATSSAAVTLKASPVQDEAT
CHHHHHHCCCCHHHHHHHHHHHCCCEEHHCCCCCCCCCCCCCCCEEEEEEECCCCHHHH
GYIAQYLMQNHYRKVAVNDSLSREIFNRYLEHLDAGKSYFIASEVESMRQYYGTRFDNEF
HHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCCE
LTGKSTSGFAVYNFFLKRAREKMRFMKAVADTAQFDFSRPETLNLDRKSDTWPLDRNELY
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCHHHH
AIWRKELKYQWLNLKYGAEKESSIRTALSKRYANRLKLLNLQKSDDAFQAYMFAVTTSFD
HHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHEEEEEEEECCC
PHTNYFSPDEFENFQIDLSRSLEGIGAKLQMESDFTVVNEIIPGGPAFKSSLLKKSDRII
CCCCCCCCCCCCCEEEEHHHHHCCCCCEEEECCCCHHHHHHCCCCHHHHHHHHHCCCCEE
GVGQGRTSEIVDVTGWRLNDVVKKIRGPKGTYVRLKILPASQAGRGPAKIVQLVRDKINL
EECCCCCCCEEEECCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCC
DEQAAQKRIMTLNNEKIGVITIPSFYLDFEAQKRHAGRYNSTSRDVARIIGELKAQKVQG
CHHHHHHHHEEECCCEEEEEECCCEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCE
IIIDLRDNGGGSLEEAVNVTGLFISNGPVVQVSNSSGGKMVLRDEDNRVLFDGPIAVLVN
EEEEEECCCCCCHHHHCCEEEEEECCCCEEEEECCCCCEEEEEECCCEEEECCCCEEEHH
RYSASASEIFAAAIQDYGRGVIIGERTFGKGTVQSIVKLTRPFSFFANKAELGQMKLTIA
HCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCHHHHCCHHHHCHHHEEHH
KFYRISGESTQHKGVVPDIGISSLIDTSSVGEDTYTSSLPWSTISKALYTPLGTTGKIST
HHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCH
GRLLQQYKARSSSQKVYQDYMRDLASLNAIRKKKVVSLNEKTFKTESERLKQIEQSWAVE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHCCHHHHHHHHHHHHCCC
QDGVKNPSKDFMLNRSAEIMSDMIPPDSGSQALK
CCCCCCCCHHHEECCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]