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The map label for this gene is prc [H]

Identifier: 119357115

GI number: 119357115

Start: 1493570

End: 1495612

Strand: Reverse

Name: prc [H]

Synonym: Cpha266_1304

Alternate gene names: 119357115

Gene position: 1495612-1493570 (Counterclockwise)

Preceding gene: 119357116

Following gene: 119357114

Centisome position: 47.72

GC content: 46.26

Gene sequence:

>2043_bases
ATGCTCAGAAAAATCTTGCTCCTCATTATTGTCTCCCTGGGGAGTTCAGTGCCGGTTTTTGCAAAAAACGCCGTGAAACC
CGGTATTTCCGTTTCGGCAACGCCACTCAAGCCCACCGAAACGCAGGAGGTAGCTGGCGTTTATATCAGCCAATATCTTC
TCCGGAATCACTTCAGAAAAATAGCGGTCAATGACTCTCTTTCACAGGAGATATTCAACCGGTATATCGACAATCTTGAC
GGCAGCAAGAACTATTTCGTCGCAAGCGAGGTGGACAGTCTGCGAAAGATTTACGGAACGCAGATTGATGACGAGTTTCT
TGTGGGAAAATCAACTGCGGGATTTTCCATTTATAATTTTTTCCTCAAACGCGCAAAAGAGAAGATGCGGTTCATGAAAG
CCGTTGTCGATACCGCGCATTTTAACTTTTCAAAGCCGGAAACCCTTGCCCTCGACAATAAAACGGCACCCTGGCCCTCT
GATAAAAGCCTGCTGAGGGATGTCTGGAGAAAAGAGCTGAAATACCTGTGGCTCAACATGAAATATTCGGGAGAAAAGAA
AAAACCAATCAGGACAACGCTTTCAAAAAGTTTTACAACCCGATTGAATCTGCTTAATCGCCAGAAGCCCGAAGACGCTT
TTCAGGCCTATAACTATGCCTTGACCACATCATTCGATCCTCATACAAGCTATTTTTCTCCGGACGAATACAAGAACTTC
CAGATCGACATGAGCCGTTCGATTGAGGGTATAGGCGCCAAACTGCAGACAGAAGGGGAGTTTACCGTCGTTGCCGAAAT
CATTCCCGGAGGACCGGCTTTTAAAAATAACCTTCTGAAAAAAGGCGACAAGATAATCGGTGTCGGTCAGGGAAAAACAG
CCGCTGTTGTCGATGTAACCGGTTGGAGAATCAATGATGTGGTCAAACTAATCCGGGGTAAAAAAGGCACGACGGTCAGC
TTGAAAATACTTCCTGCAAGCCAGAGCGGTCGGGGTCCGTCAAAAACGATACACCTGTTACGCGATAAAATCAATCTGGA
GGAACAGGCCGCAAAGAAAAGCATTTTCTTGCAGAACGGGCAGAAAATCGGCGTTATTACCATTCCCTCCTTTTATCTCG
ATTTCGAAGGAGAACAACTCAACACCGGCAACTATAACAGTACAAGCCGTGATGTCATTAAGCTTTTGAATGAACTGATT
GCCGAGCATGTTCAAGGCATCGTTATTGATCTTCGTGAAAACGGAGGCGGATCGCTTGAAGAGGCCGTAAAAGTTACAGG
CCTGTTTATTCCGAACGGACCGGTAGTACAAATCAGCAGCTCTACAGGTAGAACAACCGTACTTGACGATGAGGATGGCG
GCGTTCTGTATAACGGACCTCTTGCTGTGCTTGTAAACCGTTACAGCGCTTCAGCTTCGGAGATAGTCGCCGCTGCAATC
CAGGATTATGGACGAGGAGTGATTATTGGCGAAAGAACGTTCGGGAAGGGAACCGTTCAAAGCATCATCAATTTTTCAAG
ACCGGTTCCCGGTATTGAAAACCAGCCTGATCTTGGAGAGATAAAACTGACGATCGCAAAGTTTTACAGGGTTTCGGGAG
GCAGCACCCAACATAAAGGAGTTGTTCCCGATATTTCCATGCCTTCCATCATCGATACGTCGGCTATCGGCGAAGACACC
TATCCCAGCAGTCTGCCATGGAGCACTATTTCGCCCTCGGTGTACCAACCAACAGGCGATGTAAGTGCGGCGGAAATCGA
TATACTTCATCAAAAACAGCAGGATCGCAGCTCGAAAGATCCGCTCTACCAGTCTTATTTGAATGATCTTGGCAGACTGG
ACCAAATCCGTAAGAAAAAGTCGGTATCTCTTGAAGATTCAGCGTTCAAAACGGAAATCGAGACGATGAAAAAAATCGAA
GATCAGTGGATCAAGGAAACTGATACCGATAAAAATGCGAAAGCTGTAAAAAAAGATGTGCTGCTTGACCAGTCGGCTTC
AGTTGTTTCGGATTTATCGCTGTTGAAAAAAGGGGCGAAGTAG

Upstream 100 bases:

>100_bases
CTGGCGAGAAAGAGGGGCAATAGTTAAGTGCTGAATAACTTTTATATTGAGCATTGAAAAAGCCGGATAGAACCGAAAAA
AACCTGATCCTCCAAAAACA

Downstream 100 bases:

>100_bases
CACCTTTATTTTCCCCGGCATCGAACGGAACATGTTTTGCCTCAGGGAAACCTGTTTGAATGTCATTTCCACGCCAACGG
CCTGAGCGAGGGATAATCCG

Product: C-terminal processing peptidase-1

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MLRKILLLIIVSLGSSVPVFAKNAVKPGISVSATPLKPTETQEVAGVYISQYLLRNHFRKIAVNDSLSQEIFNRYIDNLD
GSKNYFVASEVDSLRKIYGTQIDDEFLVGKSTAGFSIYNFFLKRAKEKMRFMKAVVDTAHFNFSKPETLALDNKTAPWPS
DKSLLRDVWRKELKYLWLNMKYSGEKKKPIRTTLSKSFTTRLNLLNRQKPEDAFQAYNYALTTSFDPHTSYFSPDEYKNF
QIDMSRSIEGIGAKLQTEGEFTVVAEIIPGGPAFKNNLLKKGDKIIGVGQGKTAAVVDVTGWRINDVVKLIRGKKGTTVS
LKILPASQSGRGPSKTIHLLRDKINLEEQAAKKSIFLQNGQKIGVITIPSFYLDFEGEQLNTGNYNSTSRDVIKLLNELI
AEHVQGIVIDLRENGGGSLEEAVKVTGLFIPNGPVVQISSSTGRTTVLDDEDGGVLYNGPLAVLVNRYSASASEIVAAAI
QDYGRGVIIGERTFGKGTVQSIINFSRPVPGIENQPDLGEIKLTIAKFYRVSGGSTQHKGVVPDISMPSIIDTSAIGEDT
YPSSLPWSTISPSVYQPTGDVSAAEIDILHQKQQDRSSKDPLYQSYLNDLGRLDQIRKKKSVSLEDSAFKTEIETMKKIE
DQWIKETDTDKNAKAVKKDVLLDQSASVVSDLSLLKKGAK

Sequences:

>Translated_680_residues
MLRKILLLIIVSLGSSVPVFAKNAVKPGISVSATPLKPTETQEVAGVYISQYLLRNHFRKIAVNDSLSQEIFNRYIDNLD
GSKNYFVASEVDSLRKIYGTQIDDEFLVGKSTAGFSIYNFFLKRAKEKMRFMKAVVDTAHFNFSKPETLALDNKTAPWPS
DKSLLRDVWRKELKYLWLNMKYSGEKKKPIRTTLSKSFTTRLNLLNRQKPEDAFQAYNYALTTSFDPHTSYFSPDEYKNF
QIDMSRSIEGIGAKLQTEGEFTVVAEIIPGGPAFKNNLLKKGDKIIGVGQGKTAAVVDVTGWRINDVVKLIRGKKGTTVS
LKILPASQSGRGPSKTIHLLRDKINLEEQAAKKSIFLQNGQKIGVITIPSFYLDFEGEQLNTGNYNSTSRDVIKLLNELI
AEHVQGIVIDLRENGGGSLEEAVKVTGLFIPNGPVVQISSSTGRTTVLDDEDGGVLYNGPLAVLVNRYSASASEIVAAAI
QDYGRGVIIGERTFGKGTVQSIINFSRPVPGIENQPDLGEIKLTIAKFYRVSGGSTQHKGVVPDISMPSIIDTSAIGEDT
YPSSLPWSTISPSVYQPTGDVSAAEIDILHQKQQDRSSKDPLYQSYLNDLGRLDQIRKKKSVSLEDSAFKTEIETMKKIE
DQWIKETDTDKNAKAVKKDVLLDQSASVVSDLSLLKKGAK
>Mature_680_residues
MLRKILLLIIVSLGSSVPVFAKNAVKPGISVSATPLKPTETQEVAGVYISQYLLRNHFRKIAVNDSLSQEIFNRYIDNLD
GSKNYFVASEVDSLRKIYGTQIDDEFLVGKSTAGFSIYNFFLKRAKEKMRFMKAVVDTAHFNFSKPETLALDNKTAPWPS
DKSLLRDVWRKELKYLWLNMKYSGEKKKPIRTTLSKSFTTRLNLLNRQKPEDAFQAYNYALTTSFDPHTSYFSPDEYKNF
QIDMSRSIEGIGAKLQTEGEFTVVAEIIPGGPAFKNNLLKKGDKIIGVGQGKTAAVVDVTGWRINDVVKLIRGKKGTTVS
LKILPASQSGRGPSKTIHLLRDKINLEEQAAKKSIFLQNGQKIGVITIPSFYLDFEGEQLNTGNYNSTSRDVIKLLNELI
AEHVQGIVIDLRENGGGSLEEAVKVTGLFIPNGPVVQISSSTGRTTVLDDEDGGVLYNGPLAVLVNRYSASASEIVAAAI
QDYGRGVIIGERTFGKGTVQSIINFSRPVPGIENQPDLGEIKLTIAKFYRVSGGSTQHKGVVPDISMPSIIDTSAIGEDT
YPSSLPWSTISPSVYQPTGDVSAAEIDILHQKQQDRSSKDPLYQSYLNDLGRLDQIRKKKSVSLEDSAFKTEIETMKKIE
DQWIKETDTDKNAKAVKKDVLLDQSASVVSDLSLLKKGAK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=592, Percent_Identity=39.527027027027, Blast_Score=432, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 75157; Mature: 75157

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRKILLLIIVSLGSSVPVFAKNAVKPGISVSATPLKPTETQEVAGVYISQYLLRNHFRK
CHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHE
IAVNDSLSQEIFNRYIDNLDGSKNYFVASEVDSLRKIYGTQIDDEFLVGKSTAGFSIYNF
EECCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
FLKRAKEKMRFMKAVVDTAHFNFSKPETLALDNKTAPWPSDKSLLRDVWRKELKYLWLNM
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHEEEEEE
KYSGEKKKPIRTTLSKSFTTRLNLLNRQKPEDAFQAYNYALTTSFDPHTSYFSPDEYKNF
EECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCEEEEECCCCCCCCCCCCCCCCE
QIDMSRSIEGIGAKLQTEGEFTVVAEIIPGGPAFKNNLLKKGDKIIGVGQGKTAAVVDVT
EEECCCCCCCCCCEEECCCCEEEEEEECCCCHHHHHHHHHCCCCEEEECCCCEEEEEEEC
GWRINDVVKLIRGKKGTTVSLKILPASQSGRGPSKTIHLLRDKINLEEQAAKKSIFLQNG
CCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHEEECC
QKIGVITIPSFYLDFEGEQLNTGNYNSTSRDVIKLLNELIAEHVQGIVIDLRENGGGSLE
CEEEEEEECCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCHH
EAVKVTGLFIPNGPVVQISSSTGRTTVLDDEDGGVLYNGPLAVLVNRYSASASEIVAAAI
HHHEEEEEEECCCCEEEEECCCCCEEEEECCCCCEEECCCCEEEEECCCCCHHHHHHHHH
QDYGRGVIIGERTFGKGTVQSIINFSRPVPGIENQPDLGEIKLTIAKFYRVSGGSTQHKG
HHHCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCC
VVPDISMPSIIDTSAIGEDTYPSSLPWSTISPSVYQPTGDVSAAEIDILHQKQQDRSSKD
CCCCCCCCCHHCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
PLYQSYLNDLGRLDQIRKKKSVSLEDSAFKTEIETMKKIEDQWIKETDTDKNAKAVKKDV
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LLDQSASVVSDLSLLKKGAK
HHCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLRKILLLIIVSLGSSVPVFAKNAVKPGISVSATPLKPTETQEVAGVYISQYLLRNHFRK
CHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHE
IAVNDSLSQEIFNRYIDNLDGSKNYFVASEVDSLRKIYGTQIDDEFLVGKSTAGFSIYNF
EECCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
FLKRAKEKMRFMKAVVDTAHFNFSKPETLALDNKTAPWPSDKSLLRDVWRKELKYLWLNM
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHEEEEEE
KYSGEKKKPIRTTLSKSFTTRLNLLNRQKPEDAFQAYNYALTTSFDPHTSYFSPDEYKNF
EECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCEEEEECCCCCCCCCCCCCCCCE
QIDMSRSIEGIGAKLQTEGEFTVVAEIIPGGPAFKNNLLKKGDKIIGVGQGKTAAVVDVT
EEECCCCCCCCCCEEECCCCEEEEEEECCCCHHHHHHHHHCCCCEEEECCCCEEEEEEEC
GWRINDVVKLIRGKKGTTVSLKILPASQSGRGPSKTIHLLRDKINLEEQAAKKSIFLQNG
CCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHEEECC
QKIGVITIPSFYLDFEGEQLNTGNYNSTSRDVIKLLNELIAEHVQGIVIDLRENGGGSLE
CEEEEEEECCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCHH
EAVKVTGLFIPNGPVVQISSSTGRTTVLDDEDGGVLYNGPLAVLVNRYSASASEIVAAAI
HHHEEEEEEECCCCEEEEECCCCCEEEEECCCCCEEECCCCEEEEECCCCCHHHHHHHHH
QDYGRGVIIGERTFGKGTVQSIINFSRPVPGIENQPDLGEIKLTIAKFYRVSGGSTQHKG
HHHCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCC
VVPDISMPSIIDTSAIGEDTYPSSLPWSTISPSVYQPTGDVSAAEIDILHQKQQDRSSKD
CCCCCCCCCHHCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
PLYQSYLNDLGRLDQIRKKKSVSLEDSAFKTEIETMKKIEDQWIKETDTDKNAKAVKKDV
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LLDQSASVVSDLSLLKKGAK
HHCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]