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The map label for this gene is hdrA2 [H]

Identifier: 119357073

GI number: 119357073

Start: 1431802

End: 1433772

Strand: Reverse

Name: hdrA2 [H]

Synonym: Cpha266_1260

Alternate gene names: 119357073

Gene position: 1433772-1431802 (Counterclockwise)

Preceding gene: 119357074

Following gene: 119357072

Centisome position: 45.75

GC content: 49.67

Gene sequence:

>1971_bases
ATGGCTAAAATAGGCGTATTTGTTTGTCACTGCGGTGAAAATATCGGATCAAGAGTTGACTGCGAAAAGCTGACTGAAGC
GATGAACAACCATCCTGGCGTTTCGGTCTCCGTGCAATACAAGTATTTCTGTTCGGATCCGGGTCAGGAAAATGTCAAAA
AGGCTATCAGGGAGAACAATCTGACAGGCATTGTCGTCGCCGCCTGTTCGCCTAAAATGCACGAAGCAACGTTCAGAAAG
GCTTGTGCGGAAGCGGGTCTCAACCCTTATCTCTGCGAAATAGCAAACATTCGCGAACAGTGCTCCTGGGTGCACAGCGA
CAAGGATATGGCTACTGAAAAGGCTATTGAAATAACCCGTTCACTGATTGAAAAAGTAAAACTGAACAATGAGCTGCAAC
CAATCGAGGTTCCTGTCACCCGACGAGCTCTGGTTATCGGCGGAGGAATTGCCGGAATTCAGGCCGCCCTTGATATAGCA
AATGCCGGTCGTGAAGTTGTGCTTGTCGAACGTGAGGCTTCGCTTGGCGGACATATGTCGCAGCTTTCCGAAACATTCCC
GACGCTCGACTGTTCACAGTGCATTATGACCCCGAGAATGGTCGAAGCTGCGCAGCATCCGAAAATTCGCCTCCTGACCT
ATGCGGAAGTCGAGCAGGTAGACGGCTATATCGGAAATTTCAATGTGAAGGTGCGCCTTAAAGCCCGTTATGTCGATATG
AAATCCTGTACAGGGTGCGGCGACTGTATGCTGAAATGTCCGGTAAAAAAAATATCAAGTGAGTTTGAATGCGGTCTTGG
CAAACGTACCGCTATTTACACCCCTTTTGCACAGGCTGTCCCGAATATTCCGGTTATTGATAAAAAGAACTGCATCTACT
TTAAAAACGGAAAATGCAAGCAGTGTGCCGCAGTGTGCGAGCTCAATGCGATTGACTTCGAAATGCAGGACGAGATTATC
AATCTTGAAATAGGGGCGATTGTTGTTGCCACCGGTTTTCAGGTTCAAAATACCGCCATGTACGGAGAGTACGGGTATGG
CAAATATCCTGACGTTATTACCGGTCTTCAGTTTGAACGACTTGCTTCTGCCAGCGGACCCTCTGACGGCAAAATCCTGC
GCCCTTCCGATGGCAAAGAACCCCGGACAATCGTGTTCATTCAGTGTGCCGGTTCCCGCGATCCATCCAAAGGTGTCCGT
TACTGTTCGAAAATTTGCTGCATGTACACGGCTAAACATGCCATGCTCTATGCCCATAAGGTACATGGCAGTAAAACCAG
AATCTTTTATATGGACATCCGGGCTGCGGGAAAAGGGTATGATGAATTTACCCGCAGAGCTATCGAAGAGGACGAGGCCG
GATACGTAAGAGGAAGGGTAAGCAAGGTATGGCGTGAGAACGATAAACTCATGGTCAGGGGCGTTGATACGCTGCTTGGC
AGACCGATGGAGATTGCCGCTGATATGGTTGTGCTTGCTACAGCCATGGTGCCGCAGCCGGATGCAAAGGATTTTGCGAA
AGTGATCGGCATCACCTATGATGAATACGGATTCTACAACGAGGCCCACCTGAAGCTTCGCCCGGTTGAAACGACCAAAG
CCGGAATATTTCTTGCGGGAGCCTGCCAGTCTCCGAAAGATATTCCCGATTCGGTCGCGCAGGCATCGGCTGCCGCAAGC
AAGGTTCTCGGGCTGTTCAGCCGTGACCAGCTTGAACGCGAACCGGTGATTGCTGAAAATAATGAAAACACCTGCTCCGG
CTGTTGGGGCTGCGTTCTTGCCTGTCCCTATAATGCTATCGAGAAAAAGGATATTCTCAACCGTTCGGGCGAACTGGTCA
AGCAGGTCGCATTCGTTAATCCCGGACTCTGTCAGGGATGCGGTACATGTGTTACCTTTTGCCGGTCAAACAGCATCGAT
CTGGCAGGTTTTACCGAAAGACAGATTTTTGCTGAAGTCATGGGCCTTTAA

Upstream 100 bases:

>100_bases
GCACAGCAAGCCTTCAAAGGTCTAAAGGGTTTATTGTGCCTTAATGAACAATAAGAAACGGCTTTCACCATGAACCGCTT
CAAACTAAACGATTGAAACA

Downstream 100 bases:

>100_bases
ACGGAATGAACTTCGAATAATTACCATGAACAAACAGAACCCCGTTACCAGTGAGTACCGCTATGAGTGAACCATTTGAA
CCGAAAATCGTCGCATTTGT

Product: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 656; Mature: 655

Protein sequence:

>656_residues
MAKIGVFVCHCGENIGSRVDCEKLTEAMNNHPGVSVSVQYKYFCSDPGQENVKKAIRENNLTGIVVAACSPKMHEATFRK
ACAEAGLNPYLCEIANIREQCSWVHSDKDMATEKAIEITRSLIEKVKLNNELQPIEVPVTRRALVIGGGIAGIQAALDIA
NAGREVVLVEREASLGGHMSQLSETFPTLDCSQCIMTPRMVEAAQHPKIRLLTYAEVEQVDGYIGNFNVKVRLKARYVDM
KSCTGCGDCMLKCPVKKISSEFECGLGKRTAIYTPFAQAVPNIPVIDKKNCIYFKNGKCKQCAAVCELNAIDFEMQDEII
NLEIGAIVVATGFQVQNTAMYGEYGYGKYPDVITGLQFERLASASGPSDGKILRPSDGKEPRTIVFIQCAGSRDPSKGVR
YCSKICCMYTAKHAMLYAHKVHGSKTRIFYMDIRAAGKGYDEFTRRAIEEDEAGYVRGRVSKVWRENDKLMVRGVDTLLG
RPMEIAADMVVLATAMVPQPDAKDFAKVIGITYDEYGFYNEAHLKLRPVETTKAGIFLAGACQSPKDIPDSVAQASAAAS
KVLGLFSRDQLEREPVIAENNENTCSGCWGCVLACPYNAIEKKDILNRSGELVKQVAFVNPGLCQGCGTCVTFCRSNSID
LAGFTERQIFAEVMGL

Sequences:

>Translated_656_residues
MAKIGVFVCHCGENIGSRVDCEKLTEAMNNHPGVSVSVQYKYFCSDPGQENVKKAIRENNLTGIVVAACSPKMHEATFRK
ACAEAGLNPYLCEIANIREQCSWVHSDKDMATEKAIEITRSLIEKVKLNNELQPIEVPVTRRALVIGGGIAGIQAALDIA
NAGREVVLVEREASLGGHMSQLSETFPTLDCSQCIMTPRMVEAAQHPKIRLLTYAEVEQVDGYIGNFNVKVRLKARYVDM
KSCTGCGDCMLKCPVKKISSEFECGLGKRTAIYTPFAQAVPNIPVIDKKNCIYFKNGKCKQCAAVCELNAIDFEMQDEII
NLEIGAIVVATGFQVQNTAMYGEYGYGKYPDVITGLQFERLASASGPSDGKILRPSDGKEPRTIVFIQCAGSRDPSKGVR
YCSKICCMYTAKHAMLYAHKVHGSKTRIFYMDIRAAGKGYDEFTRRAIEEDEAGYVRGRVSKVWRENDKLMVRGVDTLLG
RPMEIAADMVVLATAMVPQPDAKDFAKVIGITYDEYGFYNEAHLKLRPVETTKAGIFLAGACQSPKDIPDSVAQASAAAS
KVLGLFSRDQLEREPVIAENNENTCSGCWGCVLACPYNAIEKKDILNRSGELVKQVAFVNPGLCQGCGTCVTFCRSNSID
LAGFTERQIFAEVMGL
>Mature_655_residues
AKIGVFVCHCGENIGSRVDCEKLTEAMNNHPGVSVSVQYKYFCSDPGQENVKKAIRENNLTGIVVAACSPKMHEATFRKA
CAEAGLNPYLCEIANIREQCSWVHSDKDMATEKAIEITRSLIEKVKLNNELQPIEVPVTRRALVIGGGIAGIQAALDIAN
AGREVVLVEREASLGGHMSQLSETFPTLDCSQCIMTPRMVEAAQHPKIRLLTYAEVEQVDGYIGNFNVKVRLKARYVDMK
SCTGCGDCMLKCPVKKISSEFECGLGKRTAIYTPFAQAVPNIPVIDKKNCIYFKNGKCKQCAAVCELNAIDFEMQDEIIN
LEIGAIVVATGFQVQNTAMYGEYGYGKYPDVITGLQFERLASASGPSDGKILRPSDGKEPRTIVFIQCAGSRDPSKGVRY
CSKICCMYTAKHAMLYAHKVHGSKTRIFYMDIRAAGKGYDEFTRRAIEEDEAGYVRGRVSKVWRENDKLMVRGVDTLLGR
PMEIAADMVVLATAMVPQPDAKDFAKVIGITYDEYGFYNEAHLKLRPVETTKAGIFLAGACQSPKDIPDSVAQASAAASK
VLGLFSRDQLEREPVIAENNENTCSGCWGCVLACPYNAIEKKDILNRSGELVKQVAFVNPGLCQGCGTCVTFCRSNSIDL
AGFTERQIFAEVMGL

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). May act as the catalytic subunit [H]

COG id: COG1148

COG function: function code C; Heterodisulfide reductase, subunit A and related polyferredoxins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003953
- InterPro:   IPR012285 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF00037 Fer4 [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 71928; Mature: 71797

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIGVFVCHCGENIGSRVDCEKLTEAMNNHPGVSVSVQYKYFCSDPGQENVKKAIRENN
CCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHHHHHCC
LTGIVVAACSPKMHEATFRKACAEAGLNPYLCEIANIREQCSWVHSDKDMATEKAIEITR
CCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
SLIEKVKLNNELQPIEVPVTRRALVIGGGIAGIQAALDIANAGREVVLVEREASLGGHMS
HHHHHHHCCCCCCCEECCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHH
QLSETFPTLDCSQCIMTPRMVEAAQHPKIRLLTYAEVEQVDGYIGNFNVKVRLKARYVDM
HHHHHCCCCCHHHHHCCHHHHHHCCCCCEEEEEEHHHHHHCCEEECEEEEEEEEEEEEEH
KSCTGCGDCMLKCPVKKISSEFECGLGKRTAIYTPFAQAVPNIPVIDKKNCIYFKNGKCK
HCCCCCCHHHEECCHHHCCCHHHCCCCCCEEEECCHHHHCCCCCEECCCCEEEEECCCHH
QCAAVCELNAIDFEMQDEIINLEIGAIVVATGFQVQNTAMYGEYGYGKYPDVITGLQFER
HHHHHHHCCCCCEEECCCEEEEEEEEEEEEECCEEECEEEECCCCCCCCCHHHCCCCHHH
LASASGPSDGKILRPSDGKEPRTIVFIQCAGSRDPSKGVRYCSKICCMYTAKHAMLYAHK
HHCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEEEE
VHGSKTRIFYMDIRAAGKGYDEFTRRAIEEDEAGYVRGRVSKVWRENDKLMVRGVDTLLG
ECCCCEEEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHC
RPMEIAADMVVLATAMVPQPDAKDFAKVIGITYDEYGFYNEAHLKLRPVETTKAGIFLAG
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEHHCCCCCCCEEEEEECCCCCCCEEEEE
ACQSPKDIPDSVAQASAAASKVLGLFSRDQLEREPVIAENNENTCSGCWGCVLACPYNAI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHCCCCHH
EKKDILNRSGELVKQVAFVNPGLCQGCGTCVTFCRSNSIDLAGFTERQIFAEVMGL
HHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AKIGVFVCHCGENIGSRVDCEKLTEAMNNHPGVSVSVQYKYFCSDPGQENVKKAIRENN
CCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHHHHHCC
LTGIVVAACSPKMHEATFRKACAEAGLNPYLCEIANIREQCSWVHSDKDMATEKAIEITR
CCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
SLIEKVKLNNELQPIEVPVTRRALVIGGGIAGIQAALDIANAGREVVLVEREASLGGHMS
HHHHHHHCCCCCCCEECCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHH
QLSETFPTLDCSQCIMTPRMVEAAQHPKIRLLTYAEVEQVDGYIGNFNVKVRLKARYVDM
HHHHHCCCCCHHHHHCCHHHHHHCCCCCEEEEEEHHHHHHCCEEECEEEEEEEEEEEEEH
KSCTGCGDCMLKCPVKKISSEFECGLGKRTAIYTPFAQAVPNIPVIDKKNCIYFKNGKCK
HCCCCCCHHHEECCHHHCCCHHHCCCCCCEEEECCHHHHCCCCCEECCCCEEEEECCCHH
QCAAVCELNAIDFEMQDEIINLEIGAIVVATGFQVQNTAMYGEYGYGKYPDVITGLQFER
HHHHHHHCCCCCEEECCCEEEEEEEEEEEEECCEEECEEEECCCCCCCCCHHHCCCCHHH
LASASGPSDGKILRPSDGKEPRTIVFIQCAGSRDPSKGVRYCSKICCMYTAKHAMLYAHK
HHCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEEEE
VHGSKTRIFYMDIRAAGKGYDEFTRRAIEEDEAGYVRGRVSKVWRENDKLMVRGVDTLLG
ECCCCEEEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHC
RPMEIAADMVVLATAMVPQPDAKDFAKVIGITYDEYGFYNEAHLKLRPVETTKAGIFLAG
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEHHCCCCCCCEEEEEECCCCCCCEEEEE
ACQSPKDIPDSVAQASAAASKVLGLFSRDQLEREPVIAENNENTCSGCWGCVLACPYNAI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHCCCCHH
EKKDILNRSGELVKQVAFVNPGLCQGCGTCVTFCRSNSIDLAGFTERQIFAEVMGL
HHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9063468; 11930014 [H]