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The map label for this gene is fabZ [H]

Identifier: 119356927

GI number: 119356927

Start: 1250420

End: 1250866

Strand: Reverse

Name: fabZ [H]

Synonym: Cpha266_1106

Alternate gene names: 119356927

Gene position: 1250866-1250420 (Counterclockwise)

Preceding gene: 119356928

Following gene: 119356926

Centisome position: 39.91

GC content: 43.4

Gene sequence:

>447_bases
ATGCGTTGGTTAATGGTTGACAAGATTATTGAAATGGAACCTGGCATTAAAGCCACAGGAGTAAAATGTTTTTCCCGTTC
CGAACTTTTTTTTATGGATCACTTTCCCGGTTATCCTCTCGTTCCCGGTGTTCTTCAGATTGAAATGATTGCTCAAACAG
GCGGTAAATGCATTATGGCAGCCAAGCCTGGTTTTCTTCCGGTACTAACCTCTGTAAAAAGCGCAAAATTCAGGAAAGCC
ATCGAACCTGGTGACAAGGCGCTTATTCATACCGAAGTTACCATTCGTCAATCCTATTCAATTGCCAAAGGAAGAATCGA
GGTTGATGGAAAAGATGTTGCTTATGCCGAGGTGATGTATGGTCATATTGCAATTCCTGCAGAAAAAATGCCTGATGCCC
CAAGCGGCGATTCTGCTTCCGGCAGAACAATAACGGGAGGAATATGA

Upstream 100 bases:

>100_bases
AATTTTCCGCATAAAGAGGCCTTTCCCGAAACGCTTCCATTTAAAAATATAGCTTTTTCTATATTCCGTATGCAAAGTAT
CAACATTTTACCCTTACACG

Downstream 100 bases:

>100_bases
GCAACATTCTCTGGAGCAAAGCCCTTGTTCCCGGCCCTGAAATCAATGAACAGCCATATACTTGCGAATATTACGGAGAG
CAAATCCATATTCCCCGTTC

Product: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MRWLMVDKIIEMEPGIKATGVKCFSRSELFFMDHFPGYPLVPGVLQIEMIAQTGGKCIMAAKPGFLPVLTSVKSAKFRKA
IEPGDKALIHTEVTIRQSYSIAKGRIEVDGKDVAYAEVMYGHIAIPAEKMPDAPSGDSASGRTITGGI

Sequences:

>Translated_148_residues
MRWLMVDKIIEMEPGIKATGVKCFSRSELFFMDHFPGYPLVPGVLQIEMIAQTGGKCIMAAKPGFLPVLTSVKSAKFRKA
IEPGDKALIHTEVTIRQSYSIAKGRIEVDGKDVAYAEVMYGHIAIPAEKMPDAPSGDSASGRTITGGI
>Mature_148_residues
MRWLMVDKIIEMEPGIKATGVKCFSRSELFFMDHFPGYPLVPGVLQIEMIAQTGGKCIMAAKPGFLPVLTSVKSAKFRKA
IEPGDKALIHTEVTIRQSYSIAKGRIEVDGKDVAYAEVMYGHIAIPAEKMPDAPSGDSASGRTITGGI

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=124, Percent_Identity=37.0967741935484, Blast_Score=73, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16029; Mature: 16029

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWLMVDKIIEMEPGIKATGVKCFSRSELFFMDHFPGYPLVPGVLQIEMIAQTGGKCIMA
CCEEEECHHHHCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCEEEEEEECCCCEEEEE
AKPGFLPVLTSVKSAKFRKAIEPGDKALIHTEVTIRQSYSIAKGRIEVDGKDVAYAEVMY
ECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCEECCEEEECCCCEEEEEEEE
GHIAIPAEKMPDAPSGDSASGRTITGGI
CEEEECHHHCCCCCCCCCCCCCEEECCC
>Mature Secondary Structure
MRWLMVDKIIEMEPGIKATGVKCFSRSELFFMDHFPGYPLVPGVLQIEMIAQTGGKCIMA
CCEEEECHHHHCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCEEEEEEECCCCEEEEE
AKPGFLPVLTSVKSAKFRKAIEPGDKALIHTEVTIRQSYSIAKGRIEVDGKDVAYAEVMY
ECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCEECCEEEECCCCEEEEEEEE
GHIAIPAEKMPDAPSGDSASGRTITGGI
CEEEECHHHCCCCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]