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The map label for this gene is metG

Identifier: 119356838

GI number: 119356838

Start: 1150722

End: 1152830

Strand: Reverse

Name: metG

Synonym: Cpha266_1011

Alternate gene names: 119356838

Gene position: 1152830-1150722 (Counterclockwise)

Preceding gene: 119356839

Following gene: 119356837

Centisome position: 36.79

GC content: 46.51

Gene sequence:

>2109_bases
ATGCTCCACGTTAAAAGAACGCTTGTCACCACAGCACTGCCCTACGCTAACGGCCCGGTCCATCTTGGACATCTTGCAGG
AGTCTATCTTCCGGCAGACCTCTATGTTCGCTACAAGCGACTCAAAGGCGACAATATCATTCATATCGGTGGCTCGGACG
AACACGGCGTCCCCATCACACTGACGGCTGAAAAAGAGGGTATCTCACCCCGTGATGTTGTTGATCGATACCATGGAATG
AACCTCGATGCGTTCACGAAATGCGGAATCTCCTTCAACTATTACGGCAGAACAACTTCAGCAGTCCATCATGCAACAGC
TCGGGAATTTTTTTCTGAAATTGAAAACAAAGGGATGTTTACCAGAAAAACCGAAAAACAGTTTTTCGACAAAAAAGCAA
ACAGGTTTCTTTCAGACCGGTATATCACAGGAACCTGTCCGATATGCAGCAATCCCGATGCAAACGGCGACCAGTGCGAA
CAGTGCGGCACCCATTTAAGCCCTCTTGAACTGATCAATCCAAAAAGCAAACTGTCCGATGCCACTCCCGAACTCAGGGA
AACCCTGCACTGGTATTTTCCTCTCGGCAGGTTTCAGAGTGAACTTGAGAGTTATGTGCAAAGCCATGATAAGGAGTGGC
GACCAAATGTCATAAACTATACAAGAACCTGGCTGAAGCAGGGCTTGAATGACCGCGCCATCACACGGGATCTCTCCTGG
GGTATCAAACTCCCTCTCGAAACCCCTGAAGCCTCGGGAAAAGTGCTTTACGTCTGGTTTGACGCCGTTCTCGGCTATAT
CTCCTTTACAAAAGAGTGGGCTGCGCAATCGGGGCAGCCTGAACTCTGGCGGGAGTACTGGCAGGATCCGGAATGTCGCA
TGATCAATTTTATAGGAAAAGATAATGTCGTTTTTCATACGCTGATGTTCCCGGCCATCCTTATGGCATGGAATAAAGGC
CGAAAAACCGATCTCTACAATCTTGCCGACAATGTTCCTGCATCTGAATTCATGAATTTTGAAGGGAGAAAATTTTCAAA
ATCAAGGAATTATGCGGTTTATCTTGGTGATTTTCTTGAAAAATTTCCTGCTGATACCCTTCGATACTGTATTGCGATGA
ACTATCCTGAAAACAAGGACAGCGACTTCAGTTGGCTGGACTTTCAGAATAGAACCAACGGCGAACTTGCCGATACGCTG
GGCAACTTCATCAAACGTTCGATTGATTTCACCAATTCCCGGTTTGACGGCAAGGTTCCCTGCGAATGCACACCGGAAGA
GTGGAAAATTCCGGGTATTGACTGGAAAGAAACCCTTGAAAAGCTCGATCAGGCATTCGAAGCATTTCATTTCAGGGAAG
CGACCTCTCTTGGAATGGATATTGCAAGAACAGCGAACCGCTTCCTTACTGAATCCGAACCATGGAAAGTGATAAAAAGC
GACAGAGAGGGTGCCGCAAAAACCATGGCGATCTCTTTAAATCTCTGTTACGCTCTTGCCCTCGTGCTTTATCCGGTCAT
TCCTGAAACAGCAAACCGTATCCTTGCCATGCTCGGCGTAGAAAAAAGCATCGATGATCAGCTTGATTCGGGAAAATCAT
GTATTGCGCAGATTCTAACTCCGCAACTTGAAAAAGGCCATCAACTCAGAAAACATTCTGAAATTCTTTTTACCAAAATC
GAGGATGCGGAACTTGCCCCGGAACTTAAAAAAATAGAGGATCTGCTTGCGCTGACTGAGGAGCGGGAAGCAAAAAACGA
GGCGAAAGCTATGGATTTCAGCCCGCTGATCAGTTTTGACGAGTTTTTAAAAGTTGACCTGAGAGTCGCAACGGTTCTTG
ATTGCCAAAAAATCAAAAAAGCCGGCAAGCTCCTCAAGCTACAGCTTAAGGTTGGCTCTGAAACTCGGCAGGTTCTTGCC
GGCATTGCAAAACATTACAGCCCGGAAGAGATGATCGGCAAAAATGTGATTCTGGTAGCCAATCTTGCCGAACGCACTAT
CCTGAATGAAATTTCCCAGGGAATGATCCTTGCCGTCGAGGGAACCGATGGAAAACTATTCCTGGTTGAACCTTCCGGCA
AAGAGATAAACGGAAAAAAGATCCAATAA

Upstream 100 bases:

>100_bases
ATGAGAAGGCGGTTCCCGATAGAAAAATTCAATTCCCTGTTTATTAAAAAGTAATCCAATCGATATCGAAATCGGTACCT
TTTGAACTTATCCCTGAACT

Downstream 100 bases:

>100_bases
AAGCTTGTTTGGGCCGGGTTTTCTATTATATTGTTGGAACAACATCGTGGGGTGGAGCAATTGGTAGCTCGTCGGGCTCA
TAACCCGAAGGTTGCAGGTT

Product: methionyl-tRNA synthetase

Products: NA

Alternate protein names: Methionine--tRNA ligase; MetRS

Number of amino acids: Translated: 702; Mature: 702

Protein sequence:

>702_residues
MLHVKRTLVTTALPYANGPVHLGHLAGVYLPADLYVRYKRLKGDNIIHIGGSDEHGVPITLTAEKEGISPRDVVDRYHGM
NLDAFTKCGISFNYYGRTTSAVHHATAREFFSEIENKGMFTRKTEKQFFDKKANRFLSDRYITGTCPICSNPDANGDQCE
QCGTHLSPLELINPKSKLSDATPELRETLHWYFPLGRFQSELESYVQSHDKEWRPNVINYTRTWLKQGLNDRAITRDLSW
GIKLPLETPEASGKVLYVWFDAVLGYISFTKEWAAQSGQPELWREYWQDPECRMINFIGKDNVVFHTLMFPAILMAWNKG
RKTDLYNLADNVPASEFMNFEGRKFSKSRNYAVYLGDFLEKFPADTLRYCIAMNYPENKDSDFSWLDFQNRTNGELADTL
GNFIKRSIDFTNSRFDGKVPCECTPEEWKIPGIDWKETLEKLDQAFEAFHFREATSLGMDIARTANRFLTESEPWKVIKS
DREGAAKTMAISLNLCYALALVLYPVIPETANRILAMLGVEKSIDDQLDSGKSCIAQILTPQLEKGHQLRKHSEILFTKI
EDAELAPELKKIEDLLALTEEREAKNEAKAMDFSPLISFDEFLKVDLRVATVLDCQKIKKAGKLLKLQLKVGSETRQVLA
GIAKHYSPEEMIGKNVILVANLAERTILNEISQGMILAVEGTDGKLFLVEPSGKEINGKKIQ

Sequences:

>Translated_702_residues
MLHVKRTLVTTALPYANGPVHLGHLAGVYLPADLYVRYKRLKGDNIIHIGGSDEHGVPITLTAEKEGISPRDVVDRYHGM
NLDAFTKCGISFNYYGRTTSAVHHATAREFFSEIENKGMFTRKTEKQFFDKKANRFLSDRYITGTCPICSNPDANGDQCE
QCGTHLSPLELINPKSKLSDATPELRETLHWYFPLGRFQSELESYVQSHDKEWRPNVINYTRTWLKQGLNDRAITRDLSW
GIKLPLETPEASGKVLYVWFDAVLGYISFTKEWAAQSGQPELWREYWQDPECRMINFIGKDNVVFHTLMFPAILMAWNKG
RKTDLYNLADNVPASEFMNFEGRKFSKSRNYAVYLGDFLEKFPADTLRYCIAMNYPENKDSDFSWLDFQNRTNGELADTL
GNFIKRSIDFTNSRFDGKVPCECTPEEWKIPGIDWKETLEKLDQAFEAFHFREATSLGMDIARTANRFLTESEPWKVIKS
DREGAAKTMAISLNLCYALALVLYPVIPETANRILAMLGVEKSIDDQLDSGKSCIAQILTPQLEKGHQLRKHSEILFTKI
EDAELAPELKKIEDLLALTEEREAKNEAKAMDFSPLISFDEFLKVDLRVATVLDCQKIKKAGKLLKLQLKVGSETRQVLA
GIAKHYSPEEMIGKNVILVANLAERTILNEISQGMILAVEGTDGKLFLVEPSGKEINGKKIQ
>Mature_702_residues
MLHVKRTLVTTALPYANGPVHLGHLAGVYLPADLYVRYKRLKGDNIIHIGGSDEHGVPITLTAEKEGISPRDVVDRYHGM
NLDAFTKCGISFNYYGRTTSAVHHATAREFFSEIENKGMFTRKTEKQFFDKKANRFLSDRYITGTCPICSNPDANGDQCE
QCGTHLSPLELINPKSKLSDATPELRETLHWYFPLGRFQSELESYVQSHDKEWRPNVINYTRTWLKQGLNDRAITRDLSW
GIKLPLETPEASGKVLYVWFDAVLGYISFTKEWAAQSGQPELWREYWQDPECRMINFIGKDNVVFHTLMFPAILMAWNKG
RKTDLYNLADNVPASEFMNFEGRKFSKSRNYAVYLGDFLEKFPADTLRYCIAMNYPENKDSDFSWLDFQNRTNGELADTL
GNFIKRSIDFTNSRFDGKVPCECTPEEWKIPGIDWKETLEKLDQAFEAFHFREATSLGMDIARTANRFLTESEPWKVIKS
DREGAAKTMAISLNLCYALALVLYPVIPETANRILAMLGVEKSIDDQLDSGKSCIAQILTPQLEKGHQLRKHSEILFTKI
EDAELAPELKKIEDLLALTEEREAKNEAKAMDFSPLISFDEFLKVDLRVATVLDCQKIKKAGKLLKLQLKVGSETRQVLA
GIAKHYSPEEMIGKNVILVANLAERTILNEISQGMILAVEGTDGKLFLVEPSGKEINGKKIQ

Specific function: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation

COG id: COG0143

COG function: function code J; Methionyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 tRNA-binding domain

Homologues:

Organism=Homo sapiens, GI14043022, Length=570, Percent_Identity=34.3859649122807, Blast_Score=350, Evalue=3e-96,
Organism=Homo sapiens, GI24308436, Length=547, Percent_Identity=23.9488117001828, Blast_Score=135, Evalue=9e-32,
Organism=Escherichia coli, GI1788432, Length=713, Percent_Identity=32.9593267882188, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI1789455, Length=88, Percent_Identity=30.6818181818182, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17540794, Length=577, Percent_Identity=33.4488734835355, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI212645096, Length=540, Percent_Identity=25.7407407407407, Blast_Score=122, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI71992781, Length=366, Percent_Identity=25.6830601092896, Blast_Score=85, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321704, Length=569, Percent_Identity=34.4463971880492, Blast_Score=357, Evalue=3e-99,
Organism=Saccharomyces cerevisiae, GI6321610, Length=559, Percent_Identity=22.7191413237925, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24655311, Length=565, Percent_Identity=34.3362831858407, Blast_Score=351, Evalue=8e-97,
Organism=Drosophila melanogaster, GI21358483, Length=532, Percent_Identity=24.4360902255639, Blast_Score=126, Evalue=4e-29,

Paralogues:

None

Copy number: 871 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): SYM_CHLPD (A1BF81)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911482.1
- ProteinModelPortal:   A1BF81
- SMR:   A1BF81
- STRING:   A1BF81
- GeneID:   4570166
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_1011
- NMPDR:   fig|290317.7.peg.1075
- eggNOG:   COG0143
- HOGENOM:   HBG721667
- OMA:   SAYQPEQ
- ProtClustDB:   PRK00133
- GO:   GO:0005737
- HAMAP:   MF_00098
- InterPro:   IPR001412
- InterPro:   IPR015413
- InterPro:   IPR014758
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR014729
- InterPro:   IPR002547
- InterPro:   IPR009080
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01041
- TIGRFAMs:   TIGR00398

Pfam domain/function: PF09334 tRNA-synt_1g; PF01588 tRNA_bind; SSF50249 Nucleic_acid_OB; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.10

Molecular weight: Translated: 79809; Mature: 79809

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00178 AA_TRNA_LIGASE_I; PS50886 TRBD

Important sites: BINDING 347-347

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHVKRTLVTTALPYANGPVHLGHLAGVYLPADLYVRYKRLKGDNIIHIGGSDEHGVPIT
CCCCHHHHHHHHCCCCCCCEEEHHHCCEEECHHHHHHHHCCCCCCEEEECCCCCCCCCEE
LTAEKEGISPRDVVDRYHGMNLDAFTKCGISFNYYGRTTSAVHHATAREFFSEIENKGMF
EEECCCCCCHHHHHHHHCCCCCHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCE
TRKTEKQFFDKKANRFLSDRYITGTCPICSNPDANGDQCEQCGTHLSPLELINPKSKLSD
EEHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHCCCCCCHHHCCCHHHHCC
ATPELRETLHWYFPLGRFQSELESYVQSHDKEWRPNVINYTRTWLKQGLNDRAITRDLSW
CCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCC
GIKLPLETPEASGKVLYVWFDAVLGYISFTKEWAAQSGQPELWREYWQDPECRMINFIGK
CEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEECC
DNVVFHTLMFPAILMAWNKGRKTDLYNLADNVPASEFMNFEGRKFSKSRNYAVYLGDFLE
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEEHHHHH
KFPADTLRYCIAMNYPENKDSDFSWLDFQNRTNGELADTLGNFIKRSIDFTNSRFDGKVP
HCCHHHHHHHHEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
CECTPEEWKIPGIDWKETLEKLDQAFEAFHFREATSLGMDIARTANRFLTESEPWKVIKS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHC
DREGAAKTMAISLNLCYALALVLYPVIPETANRILAMLGVEKSIDDQLDSGKSCIAQILT
CCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHC
PQLEKGHQLRKHSEILFTKIEDAELAPELKKIEDLLALTEEREAKNEAKAMDFSPLISFD
HHHHCCHHHHHCCCEEEEECCCHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHH
EFLKVDLRVATVLDCQKIKKAGKLLKLQLKVGSETRQVLAGIAKHYSPEEMIGKNVILVA
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHCCCEEEEE
NLAERTILNEISQGMILAVEGTDGKLFLVEPSGKEINGKKIQ
CHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MLHVKRTLVTTALPYANGPVHLGHLAGVYLPADLYVRYKRLKGDNIIHIGGSDEHGVPIT
CCCCHHHHHHHHCCCCCCCEEEHHHCCEEECHHHHHHHHCCCCCCEEEECCCCCCCCCEE
LTAEKEGISPRDVVDRYHGMNLDAFTKCGISFNYYGRTTSAVHHATAREFFSEIENKGMF
EEECCCCCCHHHHHHHHCCCCCHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCE
TRKTEKQFFDKKANRFLSDRYITGTCPICSNPDANGDQCEQCGTHLSPLELINPKSKLSD
EEHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHCCCCCCHHHCCCHHHHCC
ATPELRETLHWYFPLGRFQSELESYVQSHDKEWRPNVINYTRTWLKQGLNDRAITRDLSW
CCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCC
GIKLPLETPEASGKVLYVWFDAVLGYISFTKEWAAQSGQPELWREYWQDPECRMINFIGK
CEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEECC
DNVVFHTLMFPAILMAWNKGRKTDLYNLADNVPASEFMNFEGRKFSKSRNYAVYLGDFLE
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEEHHHHH
KFPADTLRYCIAMNYPENKDSDFSWLDFQNRTNGELADTLGNFIKRSIDFTNSRFDGKVP
HCCHHHHHHHHEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
CECTPEEWKIPGIDWKETLEKLDQAFEAFHFREATSLGMDIARTANRFLTESEPWKVIKS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHC
DREGAAKTMAISLNLCYALALVLYPVIPETANRILAMLGVEKSIDDQLDSGKSCIAQILT
CCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHC
PQLEKGHQLRKHSEILFTKIEDAELAPELKKIEDLLALTEEREAKNEAKAMDFSPLISFD
HHHHCCHHHHHCCCEEEEECCCHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHH
EFLKVDLRVATVLDCQKIKKAGKLLKLQLKVGSETRQVLAGIAKHYSPEEMIGKNVILVA
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHCCCEEEEE
NLAERTILNEISQGMILAVEGTDGKLFLVEPSGKEINGKKIQ
CHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA