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The map label for this gene is ribE [H]

Identifier: 119356780

GI number: 119356780

Start: 1094561

End: 1095217

Strand: Direct

Name: ribE [H]

Synonym: Cpha266_0952

Alternate gene names: 119356780

Gene position: 1094561-1095217 (Clockwise)

Preceding gene: 119356779

Following gene: 119356781

Centisome position: 34.93

GC content: 51.75

Gene sequence:

>657_bases
ATGTTTACCGGAATTATCAAGGATGTGGGACGGGTGAGCGGTGCGAGCCGGCAAAACGGCGGTTTGCGGCTCAGGGTGCA
GTATGGCAACGCTGAGGAGTTCAGCAATCTTTCAGTTGATGAGAGTGTCAGTATCAACGGGGCATGCCAGACTGTTGTGT
CGTTGGGTGACGGATGGCTGGAGGTGCAGAGTGTCGAAGAGACGCTTAAAAAGACAACGCTTGGCTCGCTTCGTCATGGT
TCTCTGGTGAATCTCGAACGTGCGGTGCGCCCCATTGACCGGCTTGGCGGTCATTTTGTGCTTGGTCATGTCGATTGTGC
AGCCTCAGTCGACGAGATTCGGGATCTTGGGTCGAGTCGCGAAATATGGATTTCGTTTTCTGAACGGTTCAGTCCGTTCA
TTGTGTCGGCTGGTTCCATAACTATTGACGGGATCAGTCTGACGGTTGCTGTACTTGAAAGATCCCGTTTTGCCGTGGCG
GTCATTCCCTATACATTTGCTCATACTACCATCAATGCGCTGAAGCCGGGAAGTTTTGTCAATCTTGAATTTGACATTCT
CGGCAAGTATGTTGCCCGGCAGCTTGGAACTGTTGCGCGCTCCCTGGAAGCAGATTCATTAATGGATGAGGCATGGCTCA
GGGAACAGGGGTTTTAA

Upstream 100 bases:

>100_bases
TTAATGAACAGGCGGGTTCTCTGTTTTTTGAATCCGCCTGTTTTTTTCTGGTTGCCTGTGATGGTTGTTGGTGATGTGAC
CAAACGTGAAAAGGGATGCT

Downstream 100 bases:

>100_bases
ATGGCTGATTCCGAACCTGTTCAGTCCGATCTTTTCGGCTTTTCGGCTTCCAGCGGGAGTGGTGAGCGTTTTCGCCCTCT
TGCTGAGCGCATGAGGCCCC

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MFTGIIKDVGRVSGASRQNGGLRLRVQYGNAEEFSNLSVDESVSINGACQTVVSLGDGWLEVQSVEETLKKTTLGSLRHG
SLVNLERAVRPIDRLGGHFVLGHVDCAASVDEIRDLGSSREIWISFSERFSPFIVSAGSITIDGISLTVAVLERSRFAVA
VIPYTFAHTTINALKPGSFVNLEFDILGKYVARQLGTVARSLEADSLMDEAWLREQGF

Sequences:

>Translated_218_residues
MFTGIIKDVGRVSGASRQNGGLRLRVQYGNAEEFSNLSVDESVSINGACQTVVSLGDGWLEVQSVEETLKKTTLGSLRHG
SLVNLERAVRPIDRLGGHFVLGHVDCAASVDEIRDLGSSREIWISFSERFSPFIVSAGSITIDGISLTVAVLERSRFAVA
VIPYTFAHTTINALKPGSFVNLEFDILGKYVARQLGTVARSLEADSLMDEAWLREQGF
>Mature_218_residues
MFTGIIKDVGRVSGASRQNGGLRLRVQYGNAEEFSNLSVDESVSINGACQTVVSLGDGWLEVQSVEETLKKTTLGSLRHG
SLVNLERAVRPIDRLGGHFVLGHVDCAASVDEIRDLGSSREIWISFSERFSPFIVSAGSITIDGISLTVAVLERSRFAVA
VIPYTFAHTTINALKPGSFVNLEFDILGKYVARQLGTVARSLEADSLMDEAWLREQGF

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=206, Percent_Identity=35.9223300970874, Blast_Score=107, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6319733, Length=207, Percent_Identity=33.8164251207729, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 23706; Mature: 23706

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIIKDVGRVSGASRQNGGLRLRVQYGNAEEFSNLSVDESVSINGACQTVVSLGDGWL
CCCHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHCCCCCCCCEECCHHHHHHHHHCCCCE
EVQSVEETLKKTTLGSLRHGSLVNLERAVRPIDRLGGHFVLGHVDCAASVDEIRDLGSSR
EHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHCCCEEEEEECHHHCCHHHHHHCCCCC
EIWISFSERFSPFIVSAGSITIDGISLTVAVLERSRFAVAVIPYTFAHTTINALKPGSFV
EEEEEECCCCCCEEEECCCEEECCCEEEEEEHHCCCEEEEEEEEHHHHHHHHHCCCCCEE
NLEFDILGKYVARQLGTVARSLEADSLMDEAWLREQGF
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFTGIIKDVGRVSGASRQNGGLRLRVQYGNAEEFSNLSVDESVSINGACQTVVSLGDGWL
CCCHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHCCCCCCCCEECCHHHHHHHHHCCCCE
EVQSVEETLKKTTLGSLRHGSLVNLERAVRPIDRLGGHFVLGHVDCAASVDEIRDLGSSR
EHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHCCCEEEEEECHHHCCHHHHHHCCCCC
EIWISFSERFSPFIVSAGSITIDGISLTVAVLERSRFAVAVIPYTFAHTTINALKPGSFV
EEEEEECCCCCCEEEECCCEEECCCEEEEEEHHCCCEEEEEEEEHHHHHHHHHCCCCCEE
NLEFDILGKYVARQLGTVARSLEADSLMDEAWLREQGF
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]