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The map label for this gene is pkn1 [H]

Identifier: 119356730

GI number: 119356730

Start: 1031117

End: 1032877

Strand: Direct

Name: pkn1 [H]

Synonym: Cpha266_0902

Alternate gene names: 119356730

Gene position: 1031117-1032877 (Clockwise)

Preceding gene: 119356729

Following gene: 119356731

Centisome position: 32.9

GC content: 48.32

Gene sequence:

>1761_bases
ATGACTGTTGAAGAAATTATCAGGATGCTCGATAATCCGTCAACGCTGGGCGATGCTTTGATTGAAGCGGCGAAGTTGCC
ATTCAAAGGTGACGACAGGATACGGTTCCAGCAAAAACGACAGCGATTCATTGATGGATTGAGTGATCATGAACGGCCTC
AATGGGTCGGGGAGATGAAAACTTTTTTGTCATTGTATGAATCGACCGGTAGCGTTGATAGCGCAGTCACACCACTCAGT
GCGTATCGCAATGATTTCAGTACCGATATATTTATAAGCTACGCCCGCGAAGACATGAAACGGGTTGAGCCAATTGTCAG
GGAGCTGGAAAAACACGGCTGGAGTGTTTTCTGGGATCCTGAGATTCCACCGGGGGAGACCTGGCGGGGTTATATCAAGA
AAAAGCTGGATGAATCACGTTGCGTGCTCGTTGCCTGGTCTCGTCTTTCAGTCACTTCCGAATGGGTTATCGCTGAAGCT
GATGAAGCAAAAAAACGAGGCATTCTGGTTCCTGTGCTACTCGATGCTGTTGAGCCTCCATTCGGGTTCAGCCATATTCA
TGCGGCAAATCTTTCCTGCTGGAAAAATGATAGTAATAGTCGAGCATTCAAGGAACTCGTGAATGCGGTCACCCTGAAAA
TTTCTTCGTCATCACCATCTTTCATGAACTCAATATTGGGTGAGACGTCAGTTCCTATCCCTAAGACAGCACCAGTTATT
GTACCATCAACCTCAATGCTGGAAGCACTTCGTGTAATGGTTCAAAATTGGATTTCAGTAGTTGCGAGTATCAGAACATG
GCAACCAAAAAGCCGGCAAACAGCAATTGCTATTGTGCTGGTCATGGTGTTTATTTTTGCGGTTTTATCGTATCGTTATT
TGCGTGTAACGGGTCCTTCGTCACCATCTGTTCCGGAAACTGTTCAGCCTGTGAACGCATCGCCAGCAAGGCCAGGAAAC
TTTGTTCTGATACGCGGAGGTGAGTTTACAATGGGGAGCCCGGCGAATGAATCTGGTCACGAGAGTGACGAGACTCAGCA
TCAGGTCAAAGTGAGTGATTTTTACCTGTGCAAATATGCGGTTACCCTTGCCGAGTTTAAAAAATTCATTGAAGATTCAG
GCTATCAGACTGATGCTGAAAAAGATGGCGGCAGTTATAGTTGGGATGGAATAAGTTGGGTGAAGAATGCTGGAGTTGAC
TGGCGATATGGGGTTTCAGGCAGTGTACGACCTCAAAGTGAAGAGAACCATCCTGTGTTACATGTGAGCTGGAATGACGC
TGTGGCCTATTGCAAGTGGATATCGAAAAAAACAGGAGATGCATTTCGTTTGCCAACGGAAGCTGAGTGGGAATATGCGT
GTCGAGCAGGAACAACCACACCGTTCCATACCGGCGATAACCTGACAACCGGTCAGGCGAACTATAACGGAAACTATCCG
TATACCAACAATCAGAAAGGAGTGTATCGGGAGAACACGGTTAAGGTTGATGAGTTTGCTCCGAACGCGTGGGGGTTATA
CCATATGCATGGCAATGTGTGGGAGTGGTGTGGCGACAGGTATGGGGATAAATATTATGATGAATGCAAAGCCGAAGGTG
TTGTTGAAAATCCGGTTGGCCCGGAAACCGGTTCGCTCCGTGTGCTTCGTGGAGGTGGCTGGAGCTTCAATGCGAGGAGC
TGTCGGTCGGCTTTTCGCATCGACGTCGCCCCCGACTACCGCAGCAACTACGCCGGCTTCCGCCTGGCCTTCGTCCCGTA
G

Upstream 100 bases:

>100_bases
GGATCGTGCTGGTGTTTTTGTGTGCGATATCTCGATCAGGCCGTGAAAGTCGTATCTTGAAAAAAACTTCAGAGTAACGT
CAGGGAAAAAGATAAAGAGT

Downstream 100 bases:

>100_bases
TCAGTTGGTAGCTCATGCCGACCTTTACTTTGAGCAAAGAGAGAGCTGACAAAAAAGTTGAGAACGGCAGCGAGGGACGA
GCGCCGTGCACAACTTTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 586; Mature: 585

Protein sequence:

>586_residues
MTVEEIIRMLDNPSTLGDALIEAAKLPFKGDDRIRFQQKRQRFIDGLSDHERPQWVGEMKTFLSLYESTGSVDSAVTPLS
AYRNDFSTDIFISYAREDMKRVEPIVRELEKHGWSVFWDPEIPPGETWRGYIKKKLDESRCVLVAWSRLSVTSEWVIAEA
DEAKKRGILVPVLLDAVEPPFGFSHIHAANLSCWKNDSNSRAFKELVNAVTLKISSSSPSFMNSILGETSVPIPKTAPVI
VPSTSMLEALRVMVQNWISVVASIRTWQPKSRQTAIAIVLVMVFIFAVLSYRYLRVTGPSSPSVPETVQPVNASPARPGN
FVLIRGGEFTMGSPANESGHESDETQHQVKVSDFYLCKYAVTLAEFKKFIEDSGYQTDAEKDGGSYSWDGISWVKNAGVD
WRYGVSGSVRPQSEENHPVLHVSWNDAVAYCKWISKKTGDAFRLPTEAEWEYACRAGTTTPFHTGDNLTTGQANYNGNYP
YTNNQKGVYRENTVKVDEFAPNAWGLYHMHGNVWEWCGDRYGDKYYDECKAEGVVENPVGPETGSLRVLRGGGWSFNARS
CRSAFRIDVAPDYRSNYAGFRLAFVP

Sequences:

>Translated_586_residues
MTVEEIIRMLDNPSTLGDALIEAAKLPFKGDDRIRFQQKRQRFIDGLSDHERPQWVGEMKTFLSLYESTGSVDSAVTPLS
AYRNDFSTDIFISYAREDMKRVEPIVRELEKHGWSVFWDPEIPPGETWRGYIKKKLDESRCVLVAWSRLSVTSEWVIAEA
DEAKKRGILVPVLLDAVEPPFGFSHIHAANLSCWKNDSNSRAFKELVNAVTLKISSSSPSFMNSILGETSVPIPKTAPVI
VPSTSMLEALRVMVQNWISVVASIRTWQPKSRQTAIAIVLVMVFIFAVLSYRYLRVTGPSSPSVPETVQPVNASPARPGN
FVLIRGGEFTMGSPANESGHESDETQHQVKVSDFYLCKYAVTLAEFKKFIEDSGYQTDAEKDGGSYSWDGISWVKNAGVD
WRYGVSGSVRPQSEENHPVLHVSWNDAVAYCKWISKKTGDAFRLPTEAEWEYACRAGTTTPFHTGDNLTTGQANYNGNYP
YTNNQKGVYRENTVKVDEFAPNAWGLYHMHGNVWEWCGDRYGDKYYDECKAEGVVENPVGPETGSLRVLRGGGWSFNARS
CRSAFRIDVAPDYRSNYAGFRLAFVP
>Mature_585_residues
TVEEIIRMLDNPSTLGDALIEAAKLPFKGDDRIRFQQKRQRFIDGLSDHERPQWVGEMKTFLSLYESTGSVDSAVTPLSA
YRNDFSTDIFISYAREDMKRVEPIVRELEKHGWSVFWDPEIPPGETWRGYIKKKLDESRCVLVAWSRLSVTSEWVIAEAD
EAKKRGILVPVLLDAVEPPFGFSHIHAANLSCWKNDSNSRAFKELVNAVTLKISSSSPSFMNSILGETSVPIPKTAPVIV
PSTSMLEALRVMVQNWISVVASIRTWQPKSRQTAIAIVLVMVFIFAVLSYRYLRVTGPSSPSVPETVQPVNASPARPGNF
VLIRGGEFTMGSPANESGHESDETQHQVKVSDFYLCKYAVTLAEFKKFIEDSGYQTDAEKDGGSYSWDGISWVKNAGVDW
RYGVSGSVRPQSEENHPVLHVSWNDAVAYCKWISKKTGDAFRLPTEAEWEYACRAGTTTPFHTGDNLTTGQANYNGNYPY
TNNQKGVYRENTVKVDEFAPNAWGLYHMHGNVWEWCGDRYGDKYYDECKAEGVVENPVGPETGSLRVLRGGGWSFNARSC
RSAFRIDVAPDYRSNYAGFRLAFVP

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=322, Percent_Identity=33.8509316770186, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI257470975, Length=305, Percent_Identity=34.0983606557377, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI257470977, Length=255, Percent_Identity=34.9019607843137, Blast_Score=136, Evalue=7e-32,
Organism=Homo sapiens, GI194248088, Length=292, Percent_Identity=30.4794520547945, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI194248087, Length=277, Percent_Identity=31.4079422382672, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI226437577, Length=176, Percent_Identity=36.3636363636364, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI194248090, Length=157, Percent_Identity=33.1210191082803, Blast_Score=78, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20130397, Length=355, Percent_Identity=30.1408450704225, Blast_Score=125, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 65815; Mature: 65684

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVEEIIRMLDNPSTLGDALIEAAKLPFKGDDRIRFQQKRQRFIDGLSDHERPQWVGEMK
CCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
TFLSLYESTGSVDSAVTPLSAYRNDFSTDIFISYAREDMKRVEPIVRELEKHGWSVFWDP
HHHHHHHHCCCCHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
EIPPGETWRGYIKKKLDESRCVLVAWSRLSVTSEWVIAEADEAKKRGILVPVLLDAVEPP
CCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECCCHHHHCCEEHHHHHHHCCCC
FGFSHIHAANLSCWKNDSNSRAFKELVNAVTLKISSSSPSFMNSILGETSVPIPKTAPVI
CCCCCEEECCCEEECCCCCHHHHHHHHHHEEEEECCCCCHHHHHHHCCCCCCCCCCCCEE
VPSTSMLEALRVMVQNWISVVASIRTWQPKSRQTAIAIVLVMVFIFAVLSYRYLRVTGPS
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCC
SPSVPETVQPVNASPARPGNFVLIRGGEFTMGSPANESGHESDETQHQVKVSDFYLCKYA
CCCCCCCCCCCCCCCCCCCCEEEEECCCEECCCCCCCCCCCCCCHHHEEEEHHEEHHHHH
VTLAEFKKFIEDSGYQTDAEKDGGSYSWDGISWVKNAGVDWRYGVSGSVRPQSEENHPVL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEECCCCCCCCCCCCCCCEE
HVSWNDAVAYCKWISKKTGDAFRLPTEAEWEYACRAGTTTPFHTGDNLTTGQANYNGNYP
EEECCHHHHHHHHHHCCCCCCEECCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
YTNNQKGVYRENTVKVDEFAPNAWGLYHMHGNVWEWCGDRYGDKYYDECKAEGVVENPVG
CCCCCCCCEECCCEEHHHCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHHCCCCCCCCCC
PETGSLRVLRGGGWSFNARSCRSAFRIDVAPDYRSNYAGFRLAFVP
CCCCCEEEEECCCCCCCHHHHCCEEEEECCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
TVEEIIRMLDNPSTLGDALIEAAKLPFKGDDRIRFQQKRQRFIDGLSDHERPQWVGEMK
CHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
TFLSLYESTGSVDSAVTPLSAYRNDFSTDIFISYAREDMKRVEPIVRELEKHGWSVFWDP
HHHHHHHHCCCCHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
EIPPGETWRGYIKKKLDESRCVLVAWSRLSVTSEWVIAEADEAKKRGILVPVLLDAVEPP
CCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECCCHHHHCCEEHHHHHHHCCCC
FGFSHIHAANLSCWKNDSNSRAFKELVNAVTLKISSSSPSFMNSILGETSVPIPKTAPVI
CCCCCEEECCCEEECCCCCHHHHHHHHHHEEEEECCCCCHHHHHHHCCCCCCCCCCCCEE
VPSTSMLEALRVMVQNWISVVASIRTWQPKSRQTAIAIVLVMVFIFAVLSYRYLRVTGPS
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCC
SPSVPETVQPVNASPARPGNFVLIRGGEFTMGSPANESGHESDETQHQVKVSDFYLCKYA
CCCCCCCCCCCCCCCCCCCCEEEEECCCEECCCCCCCCCCCCCCHHHEEEEHHEEHHHHH
VTLAEFKKFIEDSGYQTDAEKDGGSYSWDGISWVKNAGVDWRYGVSGSVRPQSEENHPVL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEECCCCCCCCCCCCCCCEE
HVSWNDAVAYCKWISKKTGDAFRLPTEAEWEYACRAGTTTPFHTGDNLTTGQANYNGNYP
EEECCHHHHHHHHHHCCCCCCEECCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
YTNNQKGVYRENTVKVDEFAPNAWGLYHMHGNVWEWCGDRYGDKYYDECKAEGVVENPVG
CCCCCCCCEECCCEEHHHCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHHCCCCCCCCCC
PETGSLRVLRGGGWSFNARSCRSAFRIDVAPDYRSNYAGFRLAFVP
CCCCCEEEEECCCCCCCHHHHCCEEEEECCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]