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The map label for this gene is resD [H]

Identifier: 119356708

GI number: 119356708

Start: 1004405

End: 1005115

Strand: Direct

Name: resD [H]

Synonym: Cpha266_0880

Alternate gene names: 119356708

Gene position: 1004405-1005115 (Clockwise)

Preceding gene: 119356707

Following gene: 119356709

Centisome position: 32.05

GC content: 50.49

Gene sequence:

>711_bases
ATGTCAGACCCGCTGCTTCTTGTTGTTGAGGATGACCAGAATCTTGCAAAACTGCTTGGATACAATCTTGAACGTGCAGG
GTACCGTCACCAGTTGTCTCCGACCGGTGAGGATGCGCTTGAGCAGCTTGCAAAACGACGGTTTGACCTTGTGTTGCTGG
ACCTCATGCTGCCAGGGATTGATGGTTTTGATGTATGCCGAAAAATTCGTCAGAACCAGTTGCTCAGAGATATTCCCATT
ATCATGCTGACGGCAAAAGGGGAGGAGATCGACAAGGTTCTCGGCTTTGAGCTTGGTATTGACGACTATGTTGTCAAACC
GTTCAGTCCTCGCGAGCTGACGCTGAGAATTCGTGCCATACTGAAGCGCGACAGGCGTCAGAGTGCCCAGCATCAGGAGG
TGTTGAGTGCTGCCGGTCTTGACGTCGATATCGTCCGCCATGAGGTGAAACTTGACGGAAAAGAAATCGTTCTGACGCTG
ATGGAGTTCAAGCTTCTTGTGGCTCTTCTGAAGCGCAAGGGTCAGGCACAGTCACGCGATATGCTCCTGAGCGATGTGTG
GGAAGTCGATCGTTTCATCAATACCAGAACCATAGATACCCACATCACCAGACTTCGGGAAAAACTCGGTGTAACCGGAA
GTATGATCAAAACCGTCCGCGGTCTTGGCTACAAGTTCGAGGAAGCAACGGAAAGCAGCAATGAATGCTAA

Upstream 100 bases:

>100_bases
GAAATAAAAAGCAGACTGATGCAAAACATTATCTGATTCTCACGTTTTATCGGGCTTGTCTCCCGGATAAAATCTTTAAC
CATACTTATACTTGATAGTT

Downstream 100 bases:

>100_bases
AGTATCCGTTCGACTGGGCATTGTTTTCGGCCTGATTGTCTTTCTCTCCATTGCCCTGAGTTATCTCCTTCAGGGCAAGC
TGATCAATGAACTTCTGCTT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSDPLLLVVEDDQNLAKLLGYNLERAGYRHQLSPTGEDALEQLAKRRFDLVLLDLMLPGIDGFDVCRKIRQNQLLRDIPI
IMLTAKGEEIDKVLGFELGIDDYVVKPFSPRELTLRIRAILKRDRRQSAQHQEVLSAAGLDVDIVRHEVKLDGKEIVLTL
MEFKLLVALLKRKGQAQSRDMLLSDVWEVDRFINTRTIDTHITRLREKLGVTGSMIKTVRGLGYKFEEATESSNEC

Sequences:

>Translated_236_residues
MSDPLLLVVEDDQNLAKLLGYNLERAGYRHQLSPTGEDALEQLAKRRFDLVLLDLMLPGIDGFDVCRKIRQNQLLRDIPI
IMLTAKGEEIDKVLGFELGIDDYVVKPFSPRELTLRIRAILKRDRRQSAQHQEVLSAAGLDVDIVRHEVKLDGKEIVLTL
MEFKLLVALLKRKGQAQSRDMLLSDVWEVDRFINTRTIDTHITRLREKLGVTGSMIKTVRGLGYKFEEATESSNEC
>Mature_235_residues
SDPLLLVVEDDQNLAKLLGYNLERAGYRHQLSPTGEDALEQLAKRRFDLVLLDLMLPGIDGFDVCRKIRQNQLLRDIPII
MLTAKGEEIDKVLGFELGIDDYVVKPFSPRELTLRIRAILKRDRRQSAQHQEVLSAAGLDVDIVRHEVKLDGKEIVLTLM
EFKLLVALLKRKGQAQSRDMLLSDVWEVDRFINTRTIDTHITRLREKLGVTGSMIKTVRGLGYKFEEATESSNEC

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=39.0134529147982, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=42.2907488986784, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=37.5, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=37.719298245614, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=36.7713004484305, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=36.6071428571429, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=36.986301369863, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=39.0557939914163, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=32.3404255319149, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=32.5892857142857, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=30.9417040358744, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.0357142857143, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=32.8888888888889, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=32.1888412017167, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=29.9145299145299, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=31.4814814814815, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26954; Mature: 26823

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPLLLVVEDDQNLAKLLGYNLERAGYRHQLSPTGEDALEQLAKRRFDLVLLDLMLPGI
CCCCEEEEEECCCHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
DGFDVCRKIRQNQLLRDIPIIMLTAKGEEIDKVLGFELGIDDYVVKPFSPRELTLRIRAI
CHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHH
LKRDRRQSAQHQEVLSAAGLDVDIVRHEVKLDGKEIVLTLMEFKLLVALLKRKGQAQSRD
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHH
MLLSDVWEVDRFINTRTIDTHITRLREKLGVTGSMIKTVRGLGYKFEEATESSNEC
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHCCCCCCC
>Mature Secondary Structure 
SDPLLLVVEDDQNLAKLLGYNLERAGYRHQLSPTGEDALEQLAKRRFDLVLLDLMLPGI
CCCEEEEEECCCHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
DGFDVCRKIRQNQLLRDIPIIMLTAKGEEIDKVLGFELGIDDYVVKPFSPRELTLRIRAI
CHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHH
LKRDRRQSAQHQEVLSAAGLDVDIVRHEVKLDGKEIVLTLMEFKLLVALLKRKGQAQSRD
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHH
MLLSDVWEVDRFINTRTIDTHITRLREKLGVTGSMIKTVRGLGYKFEEATESSNEC
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]