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The map label for this gene is tolQ [H]

Identifier: 119356687

GI number: 119356687

Start: 981215

End: 981892

Strand: Direct

Name: tolQ [H]

Synonym: Cpha266_0856

Alternate gene names: 119356687

Gene position: 981215-981892 (Clockwise)

Preceding gene: 119356686

Following gene: 119356688

Centisome position: 31.31

GC content: 45.72

Gene sequence:

>678_bases
ATGCCAGACTCAAGAGTCGGAATTTTTTTCATGCTTTCTGATGCCGGTCCGGCAGTGCTTGCCGTTCTCATTGTTTTGCT
TGGTTTTTCAGTGGTATCGTGGGCTATCATTGCGTTCAAGTTCGGATATGTCAACAAGTCCATAAAAGAGTCCAGAGAGT
TTCTCGATTGTTTTTTCGAGTTATCCAGTGTTGACAAGATTTTTGTTGAAAGTGAAAAGTACAGGAGCAGTTCGCTTGCA
AGGGTTTTTCGTTCCGCTTATATCGAATATCGGGCACTGGTTGAACGTAATGGTGAGAGGCATGTTGAAGAGCGCGTTGC
CCGTGCGGTGAAAAGGGAGGTAAATGCCGAGAGCAAAAGACTGGTTTATCTTGTTCCTTTTCTTGCAACGGTCGGCAATA
CCGCTCCGTTTATTGGACTGTTTGGCACAGTATGGGGCATTATGACCTCATTTCAGCAGATAGGACTGACACAGTCAGCC
TCCCTTGCTTCAGTCGCACCGGGTATATCCGAAGCACTGGTAGCAACTGCTGCCGGACTTGTTGCAGCTATTCCTGCTGT
TATAGCCTATAATTATTTCACTCAGCAGATCGCTCTCATCGATCGTGATCTTGAGGATTTTTCAGGTGAGTTTGTTACAG
CATGTATCCGGAACATACAGAAAGGGTCTGTATCATGA

Upstream 100 bases:

>100_bases
TGGTCAACACTTTTTGTGCGGTTTCAGGTTCTCTGCTTGCCTATGCAGTCATTTCATATTTTGAAATTTTTCAGTAAAAA
ACTACAATCCGTTTATCGAT

Downstream 100 bases:

>100_bases
TGCATTCAGGAAAAGGAAAGCTCTTGAGCGAGATTAACGTTACTCCCTTTATTGACGTTATGCTTGTGCTCCTGATTATT
TTTATGGTAACGGCGCCGAT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MPDSRVGIFFMLSDAGPAVLAVLIVLLGFSVVSWAIIAFKFGYVNKSIKESREFLDCFFELSSVDKIFVESEKYRSSSLA
RVFRSAYIEYRALVERNGERHVEERVARAVKREVNAESKRLVYLVPFLATVGNTAPFIGLFGTVWGIMTSFQQIGLTQSA
SLASVAPGISEALVATAAGLVAAIPAVIAYNYFTQQIALIDRDLEDFSGEFVTACIRNIQKGSVS

Sequences:

>Translated_225_residues
MPDSRVGIFFMLSDAGPAVLAVLIVLLGFSVVSWAIIAFKFGYVNKSIKESREFLDCFFELSSVDKIFVESEKYRSSSLA
RVFRSAYIEYRALVERNGERHVEERVARAVKREVNAESKRLVYLVPFLATVGNTAPFIGLFGTVWGIMTSFQQIGLTQSA
SLASVAPGISEALVATAAGLVAAIPAVIAYNYFTQQIALIDRDLEDFSGEFVTACIRNIQKGSVS
>Mature_224_residues
PDSRVGIFFMLSDAGPAVLAVLIVLLGFSVVSWAIIAFKFGYVNKSIKESREFLDCFFELSSVDKIFVESEKYRSSSLAR
VFRSAYIEYRALVERNGERHVEERVARAVKREVNAESKRLVYLVPFLATVGNTAPFIGLFGTVWGIMTSFQQIGLTQSAS
LASVAPGISEALVATAAGLVAAIPAVIAYNYFTQQIALIDRDLEDFSGEFVTACIRNIQKGSVS

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=200, Percent_Identity=39, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1789381, Length=216, Percent_Identity=36.1111111111111, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 24686; Mature: 24555

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDSRVGIFFMLSDAGPAVLAVLIVLLGFSVVSWAIIAFKFGYVNKSIKESREFLDCFFE
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSVDKIFVESEKYRSSSLARVFRSAYIEYRALVERNGERHVEERVARAVKREVNAESKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCH
LVYLVPFLATVGNTAPFIGLFGTVWGIMTSFQQIGLTQSASLASVAPGISEALVATAAGL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHH
VAAIPAVIAYNYFTQQIALIDRDLEDFSGEFVTACIRNIQKGSVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PDSRVGIFFMLSDAGPAVLAVLIVLLGFSVVSWAIIAFKFGYVNKSIKESREFLDCFFE
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSVDKIFVESEKYRSSSLARVFRSAYIEYRALVERNGERHVEERVARAVKREVNAESKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCH
LVYLVPFLATVGNTAPFIGLFGTVWGIMTSFQQIGLTQSASLASVAPGISEALVATAAGL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHH
VAAIPAVIAYNYFTQQIALIDRDLEDFSGEFVTACIRNIQKGSVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]