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The map label for this gene is nadA

Identifier: 119356652

GI number: 119356652

Start: 934487

End: 935458

Strand: Direct

Name: nadA

Synonym: Cpha266_0821

Alternate gene names: 119356652

Gene position: 934487-935458 (Clockwise)

Preceding gene: 119356651

Following gene: 119356653

Centisome position: 29.82

GC content: 50.72

Gene sequence:

>972_bases
ATGACTTCCTATTCACTACCTTTCAAGAGCAGCGGCAAGGAGATGGCAGCTTCCGGAGAACTGGCCGGAAAGATTGGCCT
TTTGAAAAAAGAGATGAACGCCATCGTTCTTGCCCACTATTACACGCTGCCGGAAATTCAGCAGGTTGCCGATGTTGTGG
GTGACAGCCTTGCGCTTGCGCGTGCTGCCGAAAAAAACAGCGCTGATGTGATTGTTTTTGCCGGCGTCTACTTCATGGCC
GAGACGGCAAAAATTATCAACCCCGACAAGCTTGTACTCATGCCGGATCTCTATGCGGGCTGTCCTCTTGCAGACAGTTG
TCCTGTCGGCGAGTTCAGAGCATTTAAACAACGGCATCCGGATGCTCTTGTTATAACGTATATCAACTCAACGGCTGAAA
TCAAGTCGCTCTCCGATATTACCTGCACCTCATCCAATGCCGAGCATATCATTCGGCAGATACCGGAAGAGCGGACAATT
ATTTTTGGCCCCGATCGCAACCTCGGAGGCTACATCATGAAAAAACTCGGCAGGGAGATGCTGCTCTGGCAGGGATTCTG
CTATGTACATGAGGCATTTCGTGAAGCATGCATTCTGCAGGCATGCAGGGAAAACCCTCAAGCCGAATTGATTGCCCATC
CGGAATGTCGCGAGGAGGTCTTGCGCCATGCTGCTTTCATCGGATCAACCCAGGCTCTTCTTGATTATACGGTTTCAGCC
CCGGCGTCATCGTTTATTGTAGCTACTGAACCCGGTATTCTCTACGAAATGCAGCGCCGTTCGCCGAAAAAGCAGTTTAT
TGCGGCTCCCAAAGACCCGGAGAACCCGAGAAGCGTCTGTAAGCAGATGAAGCAGAACACTCTCGAAAAGCTCTACCAGT
GCATGCTCGACAGGTCGCCTGAAATTATCGTGCCGGATGACCTTCGGGTTCTTGCGCTCAGACCCATCAAAAAAATGCTT
GAAATGTCATGA

Upstream 100 bases:

>100_bases
TGAAGACTATCTGAAATAGCAGTTAAAGGTCATCTGCTCAATGGAGCTTTTGGCAACTTTGCTTTAAAATATTCCCGTTG
AAATTTATTGCAACTACCCT

Downstream 100 bases:

>100_bases
AAGGATTTTGCTGAAAAAATCGGGGCTTTCTTTTTTGTTATCAAATCCATCATCCATTCATTCCTGGAGAGCATACCATG
CAGGAACATAAACAAAACGG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MTSYSLPFKSSGKEMAASGELAGKIGLLKKEMNAIVLAHYYTLPEIQQVADVVGDSLALARAAEKNSADVIVFAGVYFMA
ETAKIINPDKLVLMPDLYAGCPLADSCPVGEFRAFKQRHPDALVITYINSTAEIKSLSDITCTSSNAEHIIRQIPEERTI
IFGPDRNLGGYIMKKLGREMLLWQGFCYVHEAFREACILQACRENPQAELIAHPECREEVLRHAAFIGSTQALLDYTVSA
PASSFIVATEPGILYEMQRRSPKKQFIAAPKDPENPRSVCKQMKQNTLEKLYQCMLDRSPEIIVPDDLRVLALRPIKKML
EMS

Sequences:

>Translated_323_residues
MTSYSLPFKSSGKEMAASGELAGKIGLLKKEMNAIVLAHYYTLPEIQQVADVVGDSLALARAAEKNSADVIVFAGVYFMA
ETAKIINPDKLVLMPDLYAGCPLADSCPVGEFRAFKQRHPDALVITYINSTAEIKSLSDITCTSSNAEHIIRQIPEERTI
IFGPDRNLGGYIMKKLGREMLLWQGFCYVHEAFREACILQACRENPQAELIAHPECREEVLRHAAFIGSTQALLDYTVSA
PASSFIVATEPGILYEMQRRSPKKQFIAAPKDPENPRSVCKQMKQNTLEKLYQCMLDRSPEIIVPDDLRVLALRPIKKML
EMS
>Mature_322_residues
TSYSLPFKSSGKEMAASGELAGKIGLLKKEMNAIVLAHYYTLPEIQQVADVVGDSLALARAAEKNSADVIVFAGVYFMAE
TAKIINPDKLVLMPDLYAGCPLADSCPVGEFRAFKQRHPDALVITYINSTAEIKSLSDITCTSSNAEHIIRQIPEERTII
FGPDRNLGGYIMKKLGREMLLWQGFCYVHEAFREACILQACRENPQAELIAHPECREEVLRHAAFIGSTQALLDYTVSAP
ASSFIVATEPGILYEMQRRSPKKQFIAAPKDPENPRSVCKQMKQNTLEKLYQCMLDRSPEIIVPDDLRVLALRPIKKMLE
MS

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=311, Percent_Identity=39.871382636656, Blast_Score=218, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA_CHLPD (A1BEP5)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911296.1
- ProteinModelPortal:   A1BEP5
- SMR:   A1BEP5
- STRING:   A1BEP5
- GeneID:   4570319
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0821
- NMPDR:   fig|290317.7.peg.871
- eggNOG:   COG0379
- HOGENOM:   HBG291157
- OMA:   SMARMID
- ProtClustDB:   PRK09375
- GO:   GO:0005737
- HAMAP:   MF_00568
- InterPro:   IPR003473
- InterPro:   IPR023066
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 35973; Mature: 35842

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: BINDING 39-39 BINDING 56-56 BINDING 127-127 BINDING 144-144 BINDING 213-213 BINDING 230-230

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYSLPFKSSGKEMAASGELAGKIGLLKKEMNAIVLAHYYTLPEIQQVADVVGDSLALA
CCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCEEEEEEHHCCHHHHHHHHHHCCHHHHH
RAAEKNSADVIVFAGVYFMAETAKIINPDKLVLMPDLYAGCPLADSCPVGEFRAFKQRHP
HHHCCCCCCEEEEEHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHCCC
DALVITYINSTAEIKSLSDITCTSSNAEHIIRQIPEERTIIFGPDRNLGGYIMKKLGREM
CEEEEEEECCCHHHHCCCCCEECCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHH
LLWQGFCYVHEAFREACILQACRENPQAELIAHPECREEVLRHAAFIGSTQALLDYTVSA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCHHHHHHHHHCC
PASSFIVATEPGILYEMQRRSPKKQFIAAPKDPENPRSVCKQMKQNTLEKLYQCMLDRSP
CCCCEEEECCCCHHHHHHHCCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
EIIVPDDLRVLALRPIKKMLEMS
CEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSYSLPFKSSGKEMAASGELAGKIGLLKKEMNAIVLAHYYTLPEIQQVADVVGDSLALA
CCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCEEEEEEHHCCHHHHHHHHHHCCHHHHH
RAAEKNSADVIVFAGVYFMAETAKIINPDKLVLMPDLYAGCPLADSCPVGEFRAFKQRHP
HHHCCCCCCEEEEEHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHCCC
DALVITYINSTAEIKSLSDITCTSSNAEHIIRQIPEERTIIFGPDRNLGGYIMKKLGREM
CEEEEEEECCCHHHHCCCCCEECCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHH
LLWQGFCYVHEAFREACILQACRENPQAELIAHPECREEVLRHAAFIGSTQALLDYTVSA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCHHHHHHHHHCC
PASSFIVATEPGILYEMQRRSPKKQFIAAPKDPENPRSVCKQMKQNTLEKLYQCMLDRSP
CCCCEEEECCCCHHHHHHHCCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
EIIVPDDLRVLALRPIKKMLEMS
CEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA