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The map label for this gene is fieF [H]

Identifier: 119356578

GI number: 119356578

Start: 846728

End: 848110

Strand: Reverse

Name: fieF [H]

Synonym: Cpha266_0745

Alternate gene names: 119356578

Gene position: 848110-846728 (Counterclockwise)

Preceding gene: 119356579

Following gene: 119356577

Centisome position: 27.06

GC content: 46.93

Gene sequence:

>1383_bases
ATGGAACAAAATCATAAAAAACAGCAGGTAGCCCTCAGCTCTGCAGCAGCAAGCTTTCTCTTGACTGCACTGAAACTGGT
TGTGGGCTTAATGACCGGCAGCATCGGCATTCTTTCAGAAGCGGCGCATTCAGGGCTTGATTTCGGGGCTGCTGCCCTCA
CCTGGTTCGCGGTAAGAATAAGCGACAAACCTGCTGACAATAAACACCATTACGGGCACACAAAAGTTGAAAACATCACG
GCACTCATTGAAGCCGGCCTTCTCATTATAACCAGTGCCTGGATTATTTATGCCGCCATCCAACGCCTTGTTGAGGGCAG
CACGGAAATCGAGTTTTCCTGGTATGCCATTGCCGTGCTTGTACTTTCTATTCTTGTTGATTTTTCCCGGTCACGAGCAC
TGAAAAAAGTCGCAAGAGAAACAAACAGTGCTGCGCTTGAAGCTGATGCACTGCATTTCAGCTCCGACATCCTCAGTTCG
GCTGTCGTCCTGCTCGGACTCCTCTTTGTCTTTTTCGGAATACCCTGGGCTGATGCCGTAGCCGGTATTTTTGTTGCTGT
GCTTGTTGCCTTTGCCGCATTTAATCTCGGAAAAAAAACTATTGATGTCCTTATTGATGCTGCACCTGAAGGGATTACGG
AAAAAATTTCTGCTATAACAACGAAGATACCGGGAGTAATCACTATTGAAAAAATCAGGGTTAAACCCACAGGATCGCTG
ATTTTTATAGAAATGGTCGTAACGGTCAACAGAACATTGTCTATTGAAAAAATCCAGGATATCTGCACCGCCATCGAACA
GCATGTTCGAAAGAGTTTTCCTGTTGCCGATATGACTATCGACACCCGACCCATTGCGCTCAACAGCGAGACCATTGTTG
AACGTGTCCACGTTATCAGCCTCAATCACAACCTTCATGCGCACAACATTGCCACAAACATGCATGAGATGAAAAAACAT
ATCACCTTTGATGTCGAAATAGACCAACGCCTGAGCATAAAACAGGCTCATGATATTGTTACGGCGCTTGAAGAAGATCT
GCATCGGGAGTTTGATGATGACCTGGATATCTGTATTCACCTCGATCCGCTCCGCTGCGAGGAAAGAAAATCCCGGGCAC
TCCTGCCGCAAGAGGAAGTACTCGTAAGAAACATCATTATCAATGCGGCAACCGGGATTGAAAACATTCAGGATGTTCAC
GACATCCGGATCCGAAAAACGGACAAACACAAGCTCTTTATCACCCTGCACTGTTCATTCAATGACGAGGTGCTTCTTGA
AGAGGTCCATGCGCTGACCAGTCGCCTTGAAGGGGCTATCTATCAGACCATCCCCGAAGCCTGCCGGGTTATCATCCATG
CCGAACCACTTTTTAATCTCTGA

Upstream 100 bases:

>100_bases
ACCTTTTTTTCAAATGAAGATCTGTTGGCTATAAATACTATCTGATCAAACTTGATATCCTGTCTCCACAAAACCCCGAT
CACTCCCTTTGCGGAAATCC

Downstream 100 bases:

>100_bases
GGGCTAATTCCGGGAATCGGTGCGCAACAAAAGCATCGGCACACCATGGCTTCAGGAGAAAATTCCGCCATTGCCGGTTG
GCGCCATAACCTGCCTCATT

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MEQNHKKQQVALSSAAASFLLTALKLVVGLMTGSIGILSEAAHSGLDFGAAALTWFAVRISDKPADNKHHYGHTKVENIT
ALIEAGLLIITSAWIIYAAIQRLVEGSTEIEFSWYAIAVLVLSILVDFSRSRALKKVARETNSAALEADALHFSSDILSS
AVVLLGLLFVFFGIPWADAVAGIFVAVLVAFAAFNLGKKTIDVLIDAAPEGITEKISAITTKIPGVITIEKIRVKPTGSL
IFIEMVVTVNRTLSIEKIQDICTAIEQHVRKSFPVADMTIDTRPIALNSETIVERVHVISLNHNLHAHNIATNMHEMKKH
ITFDVEIDQRLSIKQAHDIVTALEEDLHREFDDDLDICIHLDPLRCEERKSRALLPQEEVLVRNIIINAATGIENIQDVH
DIRIRKTDKHKLFITLHCSFNDEVLLEEVHALTSRLEGAIYQTIPEACRVIIHAEPLFNL

Sequences:

>Translated_460_residues
MEQNHKKQQVALSSAAASFLLTALKLVVGLMTGSIGILSEAAHSGLDFGAAALTWFAVRISDKPADNKHHYGHTKVENIT
ALIEAGLLIITSAWIIYAAIQRLVEGSTEIEFSWYAIAVLVLSILVDFSRSRALKKVARETNSAALEADALHFSSDILSS
AVVLLGLLFVFFGIPWADAVAGIFVAVLVAFAAFNLGKKTIDVLIDAAPEGITEKISAITTKIPGVITIEKIRVKPTGSL
IFIEMVVTVNRTLSIEKIQDICTAIEQHVRKSFPVADMTIDTRPIALNSETIVERVHVISLNHNLHAHNIATNMHEMKKH
ITFDVEIDQRLSIKQAHDIVTALEEDLHREFDDDLDICIHLDPLRCEERKSRALLPQEEVLVRNIIINAATGIENIQDVH
DIRIRKTDKHKLFITLHCSFNDEVLLEEVHALTSRLEGAIYQTIPEACRVIIHAEPLFNL
>Mature_460_residues
MEQNHKKQQVALSSAAASFLLTALKLVVGLMTGSIGILSEAAHSGLDFGAAALTWFAVRISDKPADNKHHYGHTKVENIT
ALIEAGLLIITSAWIIYAAIQRLVEGSTEIEFSWYAIAVLVLSILVDFSRSRALKKVARETNSAALEADALHFSSDILSS
AVVLLGLLFVFFGIPWADAVAGIFVAVLVAFAAFNLGKKTIDVLIDAAPEGITEKISAITTKIPGVITIEKIRVKPTGSL
IFIEMVVTVNRTLSIEKIQDICTAIEQHVRKSFPVADMTIDTRPIALNSETIVERVHVISLNHNLHAHNIATNMHEMKKH
ITFDVEIDQRLSIKQAHDIVTALEEDLHREFDDDLDICIHLDPLRCEERKSRALLPQEEVLVRNIIINAATGIENIQDVH
DIRIRKTDKHKLFITLHCSFNDEVLLEEVHALTSRLEGAIYQTIPEACRVIIHAEPLFNL

Specific function: Cation-efflux transporter that may have a role in detoxification [H]

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790349, Length=273, Percent_Identity=28.2051282051282, Blast_Score=119, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI193210990, Length=307, Percent_Identity=20.8469055374593, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 50926; Mature: 50926

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQNHKKQQVALSSAAASFLLTALKLVVGLMTGSIGILSEAAHSGLDFGAAALTWFAVRI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHEEEEE
SDKPADNKHHYGHTKVENITALIEAGLLIITSAWIIYAAIQRLVEGSTEIEFSWYAIAVL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
VLSILVDFSRSRALKKVARETNSAALEADALHFSSDILSSAVVLLGLLFVFFGIPWADAV
HHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AGIFVAVLVAFAAFNLGKKTIDVLIDAAPEGITEKISAITTKIPGVITIEKIRVKPTGSL
HHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCE
IFIEMVVTVNRTLSIEKIQDICTAIEQHVRKSFPVADMTIDTRPIALNSETIVERVHVIS
EEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEECHHHHHHEEEEEE
LNHNLHAHNIATNMHEMKKHITFDVEIDQRLSIKQAHDIVTALEEDLHREFDDDLDICIH
ECCCCCHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LDPLRCEERKSRALLPQEEVLVRNIIINAATGIENIQDVHDIRIRKTDKHKLFITLHCSF
ECCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCEEEEEEEECC
NDEVLLEEVHALTSRLEGAIYQTIPEACRVIIHAEPLFNL
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCCCCC
>Mature Secondary Structure
MEQNHKKQQVALSSAAASFLLTALKLVVGLMTGSIGILSEAAHSGLDFGAAALTWFAVRI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHEEEEE
SDKPADNKHHYGHTKVENITALIEAGLLIITSAWIIYAAIQRLVEGSTEIEFSWYAIAVL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
VLSILVDFSRSRALKKVARETNSAALEADALHFSSDILSSAVVLLGLLFVFFGIPWADAV
HHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AGIFVAVLVAFAAFNLGKKTIDVLIDAAPEGITEKISAITTKIPGVITIEKIRVKPTGSL
HHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCE
IFIEMVVTVNRTLSIEKIQDICTAIEQHVRKSFPVADMTIDTRPIALNSETIVERVHVIS
EEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEECHHHHHHEEEEEE
LNHNLHAHNIATNMHEMKKHITFDVEIDQRLSIKQAHDIVTALEEDLHREFDDDLDICIH
ECCCCCHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LDPLRCEERKSRALLPQEEVLVRNIIINAATGIENIQDVHDIRIRKTDKHKLFITLHCSF
ECCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCEEEEEEEECC
NDEVLLEEVHALTSRLEGAIYQTIPEACRVIIHAEPLFNL
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA