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The map label for this gene is hypA [H]

Identifier: 119356554

GI number: 119356554

Start: 821705

End: 822082

Strand: Direct

Name: hypA [H]

Synonym: Cpha266_0720

Alternate gene names: 119356554

Gene position: 821705-822082 (Clockwise)

Preceding gene: 119356551

Following gene: 119356555

Centisome position: 26.22

GC content: 49.21

Gene sequence:

>378_bases
GTGAACGAACCCGGAATAAAGGCTGTTATGCATGAAATGTCGGTAGCTATCTCCATTGTCGATGCTGTATGCGAAACGGC
TCGAAAAGATGGGGCTCTTTCAGTTTCCCGTATTGAGCTTGTGGTAGGAAGGCTTGCGGGTCTACAAGTCGAATCGCTTC
GGTTCTGCTTTTCTTCGGCAGCAAAGGGGACTCTTGCTGAAGACGCCGTTCTTGCTGTTGAGGAGCCTGAAGCCAGAGGG
GAGTGCGGTGATTGCGGATCGAGGTTTCCCGTCTCTTTTTTTTATGCGGAGTGCCCGGTTTGCCGTTCACTGAAAGTTCG
CATTGTTTCGGGAGAAGAGTTCATGATTCAGTCAATTATTATCGAAGAGGGAGAATAA

Upstream 100 bases:

>100_bases
AGGGTTATCTTCTTGTTTTCCTGAAAAAGTCATGCTCCACATGGAATTTTGTTGCCAATGATGGTTATAGCCTGCTGTAT
GCAAAGGAGATGTTACTCTT

Downstream 100 bases:

>100_bases
TAACTATGTGTGATACCTGTGGTTGCTCAACGGACGGAGGAGCGCTGCTTCGCAAGCCGGGAGACAGCGATTACCATGTT
CATATAGGCGATGAAGGGCA

Product: hydrogenase expression/synthesis, HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MNEPGIKAVMHEMSVAISIVDAVCETARKDGALSVSRIELVVGRLAGLQVESLRFCFSSAAKGTLAEDAVLAVEEPEARG
ECGDCGSRFPVSFFYAECPVCRSLKVRIVSGEEFMIQSIIIEEGE

Sequences:

>Translated_125_residues
MNEPGIKAVMHEMSVAISIVDAVCETARKDGALSVSRIELVVGRLAGLQVESLRFCFSSAAKGTLAEDAVLAVEEPEARG
ECGDCGSRFPVSFFYAECPVCRSLKVRIVSGEEFMIQSIIIEEGE
>Mature_125_residues
MNEPGIKAVMHEMSVAISIVDAVCETARKDGALSVSRIELVVGRLAGLQVESLRFCFSSAAKGTLAEDAVLAVEEPEARG
ECGDCGSRFPVSFFYAECPVCRSLKVRIVSGEEFMIQSIIIEEGE

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789365, Length=113, Percent_Identity=27.4336283185841, Blast_Score=60, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 13446; Mature: 13446

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEPGIKAVMHEMSVAISIVDAVCETARKDGALSVSRIELVVGRLAGLQVESLRFCFSSA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHC
AKGTLAEDAVLAVEEPEARGECGDCGSRFPVSFFYAECPVCRSLKVRIVSGEEFMIQSII
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCHHEEHHHE
IEEGE
ECCCC
>Mature Secondary Structure
MNEPGIKAVMHEMSVAISIVDAVCETARKDGALSVSRIELVVGRLAGLQVESLRFCFSSA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHC
AKGTLAEDAVLAVEEPEARGECGDCGSRFPVSFFYAECPVCRSLKVRIVSGEEFMIQSII
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCHHEEHHHE
IEEGE
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA