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The map label for this gene is fbp [H]

Identifier: 119356521

GI number: 119356521

Start: 783597

End: 784595

Strand: Reverse

Name: fbp [H]

Synonym: Cpha266_0686

Alternate gene names: 119356521

Gene position: 784595-783597 (Counterclockwise)

Preceding gene: 119356523

Following gene: 119356519

Centisome position: 25.04

GC content: 49.25

Gene sequence:

>999_bases
ATGAACCTTATCACCATTGAGCGACACATTCTGGAACAACAGAAATTTTTTCCTGAATTTACCGGGGAGCTCACCGATCT
TCTCAACGATGTTGCATTTGCTGCAAAACTTGTCCGCCGTGAGGTGGTTCGAGCAGGCCTGGTAGATATTCTCGGATTTA
CAGGCGACACGAATATTCAGGGCGAACAGGTAAAAAAACTTGACCTTTTTGCTAATGACAAAATCATCAACGCAATCGGT
CAGCATGGACGGTTTGCCATCATGGGTTCCGAAGAGAATGACGGAATCATCATTCCTCCAAAAAACGAAACCGGCAGCTA
CGCCCTGCTTTTTGACCCGCTTGACGGTTCATCGAATATTGACGTCAATGTCAGTGTCGGCACTATTTTCTCGATCTATA
AACTCAAGGGAGATGACCCCGGCAAAGCAAGTCTCAATGACTGCCTGCAACATGGCTATGAGCAGGTGGCCGCCGGATAT
GTTATTTACGGATCATCGGTCGTCATGGTCTACACAACCGGACACGGCGTTCACGGATTCACCTACGACCCGACAATCGG
CGAGTTCCTTCTTTCCCATGAAAATATCGTTACCCCGAAAAGCGGCAAGTATTATTCCATCAATGAGGGATCATACGGGC
AGTTCAACGAGGGAACAAAAAAATATCTCGACTATATCAAAGAGGAAGACCCGGCAACTGGACGCCCTTACAGCACCCGC
TATATCGGCTCACTGGTGGCTGATTTTCACCGCAATCTGCTCACTGGCGGCATCTTTGTCTATCCGCCAACCATAACTCA
CCCGAACGGCAAACTCAGGCTTATGTACGAAGCCAATCCTTTGGCATTCATCTGCGAGCAGGCCGGTGGACGAGCGACAA
ACGGTAAAGAGCGCATTCTTGACCTCCAGCCATCTGAGCTCCATCAGCGTACCCCGCTCTATATCGGTAGTGAAGCGGAC
GTTATGATAGCAGAGGAGTTCGAGCAGGGCAAGCGATAA

Upstream 100 bases:

>100_bases
CATTTGAAATATCAGTCGAATACTCTACATTTAAAAGCAGTGTTACCTCTGATTAATCCTGTACTCTGCCGTTTATCAAC
CATACCGGAAACCACGAACG

Downstream 100 bases:

>100_bases
ACAAAGCGTTCTCTGCATGCCTTGCACGATGTTTCACAACGGGCAGTGTTTGTTTCTGCTGAACAAGGAACAACCACTGC
CTTTCGTGTTTCATCATATA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNLITIERHILEQQKFFPEFTGELTDLLNDVAFAAKLVRREVVRAGLVDILGFTGDTNIQGEQVKKLDLFANDKIINAIG
QHGRFAIMGSEENDGIIIPPKNETGSYALLFDPLDGSSNIDVNVSVGTIFSIYKLKGDDPGKASLNDCLQHGYEQVAAGY
VIYGSSVVMVYTTGHGVHGFTYDPTIGEFLLSHENIVTPKSGKYYSINEGSYGQFNEGTKKYLDYIKEEDPATGRPYSTR
YIGSLVADFHRNLLTGGIFVYPPTITHPNGKLRLMYEANPLAFICEQAGGRATNGKERILDLQPSELHQRTPLYIGSEAD
VMIAEEFEQGKR

Sequences:

>Translated_332_residues
MNLITIERHILEQQKFFPEFTGELTDLLNDVAFAAKLVRREVVRAGLVDILGFTGDTNIQGEQVKKLDLFANDKIINAIG
QHGRFAIMGSEENDGIIIPPKNETGSYALLFDPLDGSSNIDVNVSVGTIFSIYKLKGDDPGKASLNDCLQHGYEQVAAGY
VIYGSSVVMVYTTGHGVHGFTYDPTIGEFLLSHENIVTPKSGKYYSINEGSYGQFNEGTKKYLDYIKEEDPATGRPYSTR
YIGSLVADFHRNLLTGGIFVYPPTITHPNGKLRLMYEANPLAFICEQAGGRATNGKERILDLQPSELHQRTPLYIGSEAD
VMIAEEFEQGKR
>Mature_332_residues
MNLITIERHILEQQKFFPEFTGELTDLLNDVAFAAKLVRREVVRAGLVDILGFTGDTNIQGEQVKKLDLFANDKIINAIG
QHGRFAIMGSEENDGIIIPPKNETGSYALLFDPLDGSSNIDVNVSVGTIFSIYKLKGDDPGKASLNDCLQHGYEQVAAGY
VIYGSSVVMVYTTGHGVHGFTYDPTIGEFLLSHENIVTPKSGKYYSINEGSYGQFNEGTKKYLDYIKEEDPATGRPYSTR
YIGSLVADFHRNLLTGGIFVYPPTITHPNGKLRLMYEANPLAFICEQAGGRATNGKERILDLQPSELHQRTPLYIGSEAD
VMIAEEFEQGKR

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI22907028, Length=321, Percent_Identity=45.1713395638629, Blast_Score=274, Evalue=8e-74,
Organism=Homo sapiens, GI189083692, Length=318, Percent_Identity=45.5974842767296, Blast_Score=274, Evalue=9e-74,
Organism=Homo sapiens, GI16579888, Length=318, Percent_Identity=45.5974842767296, Blast_Score=274, Evalue=9e-74,
Organism=Escherichia coli, GI1790679, Length=323, Percent_Identity=55.1083591331269, Blast_Score=359, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17508131, Length=324, Percent_Identity=49.0740740740741, Blast_Score=327, Evalue=6e-90,
Organism=Saccharomyces cerevisiae, GI6323409, Length=322, Percent_Identity=46.583850931677, Blast_Score=292, Evalue=5e-80,
Organism=Drosophila melanogaster, GI45550998, Length=320, Percent_Identity=47.1875, Blast_Score=304, Evalue=7e-83,
Organism=Drosophila melanogaster, GI19921562, Length=320, Percent_Identity=47.1875, Blast_Score=303, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 36743; Mature: 36743

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLITIERHILEQQKFFPEFTGELTDLLNDVAFAAKLVRREVVRAGLVDILGFTGDTNIQ
CCEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GEQVKKLDLFANDKIINAIGQHGRFAIMGSEENDGIIIPPKNETGSYALLFDPLDGSSNI
HHHHEEEHHHCCCHHHHHHCCCCCEEEEECCCCCCEEECCCCCCCCEEEEEECCCCCCCE
DVNVSVGTIFSIYKLKGDDPGKASLNDCLQHGYEQVAAGYVIYGSSVVMVYTTGHGVHGF
EEEEEHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEECCCEEEEEEECCCCCCE
TYDPTIGEFLLSHENIVTPKSGKYYSINEGSYGQFNEGTKKYLDYIKEEDPATGRPYSTR
EECCCHHHHHHCCCCEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHH
YIGSLVADFHRNLLTGGIFVYPPTITHPNGKLRLMYEANPLAFICEQAGGRATNGKERIL
HHHHHHHHHHHHHHHCCEEEECCEEECCCCCEEEEEECCCCEEEEECCCCCCCCCHHHEE
DLQPSELHQRTPLYIGSEADVMIAEEFEQGKR
ECCHHHHHCCCCEEECCCCCEEEEEHHHCCCC
>Mature Secondary Structure
MNLITIERHILEQQKFFPEFTGELTDLLNDVAFAAKLVRREVVRAGLVDILGFTGDTNIQ
CCEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GEQVKKLDLFANDKIINAIGQHGRFAIMGSEENDGIIIPPKNETGSYALLFDPLDGSSNI
HHHHEEEHHHCCCHHHHHHCCCCCEEEEECCCCCCEEECCCCCCCCEEEEEECCCCCCCE
DVNVSVGTIFSIYKLKGDDPGKASLNDCLQHGYEQVAAGYVIYGSSVVMVYTTGHGVHGF
EEEEEHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEECCCEEEEEEECCCCCCE
TYDPTIGEFLLSHENIVTPKSGKYYSINEGSYGQFNEGTKKYLDYIKEEDPATGRPYSTR
EECCCHHHHHHCCCCEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHH
YIGSLVADFHRNLLTGGIFVYPPTITHPNGKLRLMYEANPLAFICEQAGGRATNGKERIL
HHHHHHHHHHHHHHHCCEEEECCEEECCCCCEEEEEECCCCEEEEECCCCCCCCCHHHEE
DLQPSELHQRTPLYIGSEADVMIAEEFEQGKR
ECCHHHHHCCCCEEECCCCCEEEEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA