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The map label for this gene is pdxJ

Identifier: 119356502

GI number: 119356502

Start: 760071

End: 760781

Strand: Reverse

Name: pdxJ

Synonym: Cpha266_0667

Alternate gene names: 119356502

Gene position: 760781-760071 (Counterclockwise)

Preceding gene: 119356506

Following gene: 119356501

Centisome position: 24.28

GC content: 52.46

Gene sequence:

>711_bases
ATGAGATTAGCCGTTAATATTGACCATATTGCCACCCTGCGTAACGCCAGGGGTGAACAGGAACCCGACCCGGTTGCAGC
AGCCCTGCTTGCCGAACGGTGCGGTGCGGCAGGCATTGTCTGCCACCTGCGTGAAGATCGTCGCCATATCAAGGACCTTG
ATCTTGCCCGGCTCCGCGAAGCTGTGACAACAAAGCTTGACCTTGAGATGGCCATGACCGGGGAGCTTCAGGAGATAGCT
CTGAAAACAAAACCTGAACTCATCACTCTTGTACCTGAAAAAAGAGAGGAACTGACCACCGAGGGGGGGTTTGACGTTGC
CCGTCACTTTGCCGTACTGAAAGAATTTCTGAAACCGCTCAATGATAACGGTATTGAAGTCAGTCTCTTTATAGAACCTG
AAAAAAAAGCTGTCGACCTTGCCAGAGAGGCGGGCGCTGACCTTGTGGAGCTGCACACCGGACTCTATGCGCAGAAAGAG
CTTGAGAATAACACTGACCTGGAACTGCAAAGAATACGTGAAGCTGCAACCTATGCAAAAAGTATAGGGCTCAGGGTCGT
TGCCGGTCACGGACTCAACTACCGGAACATCGGGCCGTTCAGGGAGATCCCTGAGATCGAAGAGGTAAGCATCGGTCATG
CCATTATTGCCCGCGCAGTGTTCACGGGGCTTGATGAAGCGGTCAGGGAGATGCTTCGTCTTATTCAGTAG

Upstream 100 bases:

>100_bases
TGCCCGTTGCCCCTTTTTTCATTACCTTCGCTTAAGATAGCAGGCCGGATAACCTGCACAGCGATATTTTCCGATTGTTG
ACTATTGACCCTTCGATACC

Downstream 100 bases:

>100_bases
AATCGTTGCAAACAGTCACTCATGCCGCAATCTGCCGACAACCGTATTATCGTCATCCTTGCAACCGCAAACCGGGACAA
GGTTAAAGAGCTTCGACCGC

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MRLAVNIDHIATLRNARGEQEPDPVAAALLAERCGAAGIVCHLREDRRHIKDLDLARLREAVTTKLDLEMAMTGELQEIA
LKTKPELITLVPEKREELTTEGGFDVARHFAVLKEFLKPLNDNGIEVSLFIEPEKKAVDLAREAGADLVELHTGLYAQKE
LENNTDLELQRIREAATYAKSIGLRVVAGHGLNYRNIGPFREIPEIEEVSIGHAIIARAVFTGLDEAVREMLRLIQ

Sequences:

>Translated_236_residues
MRLAVNIDHIATLRNARGEQEPDPVAAALLAERCGAAGIVCHLREDRRHIKDLDLARLREAVTTKLDLEMAMTGELQEIA
LKTKPELITLVPEKREELTTEGGFDVARHFAVLKEFLKPLNDNGIEVSLFIEPEKKAVDLAREAGADLVELHTGLYAQKE
LENNTDLELQRIREAATYAKSIGLRVVAGHGLNYRNIGPFREIPEIEEVSIGHAIIARAVFTGLDEAVREMLRLIQ
>Mature_236_residues
MRLAVNIDHIATLRNARGEQEPDPVAAALLAERCGAAGIVCHLREDRRHIKDLDLARLREAVTTKLDLEMAMTGELQEIA
LKTKPELITLVPEKREELTTEGGFDVARHFAVLKEFLKPLNDNGIEVSLFIEPEKKAVDLAREAGADLVELHTGLYAQKE
LENNTDLELQRIREAATYAKSIGLRVVAGHGLNYRNIGPFREIPEIEEVSIGHAIIARAVFTGLDEAVREMLRLIQ

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family

Homologues:

Organism=Escherichia coli, GI1788917, Length=233, Percent_Identity=54.9356223175966, Blast_Score=251, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXJ_CHLPD (A1BE95)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911146.1
- ProteinModelPortal:   A1BE95
- SMR:   A1BE95
- STRING:   A1BE95
- GeneID:   4569821
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0667
- NMPDR:   fig|290317.7.peg.700
- eggNOG:   COG0854
- HOGENOM:   HBG299314
- OMA:   AGHGLNY
- ProtClustDB:   PRK05265
- GO:   GO:0005737
- HAMAP:   MF_00279
- InterPro:   IPR013785
- InterPro:   IPR004569
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00559

Pfam domain/function: PF03740 PdxJ; SSF63892 PyrdxlP_synth_PdxJ

EC number: =2.6.99.2

Molecular weight: Translated: 26311; Mature: 26311

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: ACT_SITE 42-42 ACT_SITE 69-69 ACT_SITE 190-190 BINDING 6-6 BINDING 17-17 BINDING 44-44 BINDING 49-49 BINDING 99-99 BINDING 191-191

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAVNIDHIATLRNARGEQEPDPVAAALLAERCGAAGIVCHLREDRRHIKDLDLARLRE
CEEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCHHHHHHH
AVTTKLDLEMAMTGELQEIALKTKPELITLVPEKREELTTEGGFDVARHFAVLKEFLKPL
HHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCHHHHHCCCCCHHHHHHHHHHHHHHHHC
NDNGIEVSLFIEPEKKAVDLAREAGADLVELHTGLYAQKELENNTDLELQRIREAATYAK
CCCCEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SIGLRVVAGHGLNYRNIGPFREIPEIEEVSIGHAIIARAVFTGLDEAVREMLRLIQ
HCCEEEEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MRLAVNIDHIATLRNARGEQEPDPVAAALLAERCGAAGIVCHLREDRRHIKDLDLARLRE
CEEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCHHHHHHH
AVTTKLDLEMAMTGELQEIALKTKPELITLVPEKREELTTEGGFDVARHFAVLKEFLKPL
HHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCHHHHHCCCCCHHHHHHHHHHHHHHHHC
NDNGIEVSLFIEPEKKAVDLAREAGADLVELHTGLYAQKELENNTDLELQRIREAATYAK
CCCCEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SIGLRVVAGHGLNYRNIGPFREIPEIEEVSIGHAIIARAVFTGLDEAVREMLRLIQ
HCCEEEEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA