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The map label for this gene is argD [H]

Identifier: 119356445

GI number: 119356445

Start: 680963

End: 682162

Strand: Reverse

Name: argD [H]

Synonym: Cpha266_0609

Alternate gene names: 119356445

Gene position: 682162-680963 (Counterclockwise)

Preceding gene: 119356446

Following gene: 119356444

Centisome position: 21.77

GC content: 46.0

Gene sequence:

>1200_bases
ATGAACATGAAACAAATGCCCATAACACCGGAAAGTGAACAGGCGCTTTTTTTCCATAACTATGCAAGACTCCCAATAGC
TATAACCCATGGAGATGGTTCATGGCTTGTCAGCGATACGGGTATACGCTATCTCGATATGATTGCCGGCATCGGAGTCA
ATGCCCTCGGATATGGCGACAAGCGCCTTATCAACGCGATAAACGAACAGGCAGCCAAAATCATCCATGCATCCAATCTC
TTTCTTTTGCAGCCACAGTTTGCTTTGGCAGAGAAACTTCTTGAAATTTCCGGGCTTTCCAAGGTATTTTTTGCCAACAG
CGGCACTGAAGCTATTGAAGCGTCCATCAAAATGGCAAGAAAATGGGCAGCCTCTTCCGGCAACGATCGCAAAAAAGAGA
TATTATCGCTCTCAAACTGTTTTCATGGAAGAACATATGGCGCCATGTCCTTGACGGCAAAGGCAAAATATACCGATGGC
TTCGAACCGTTGCTGCCAGATACCGGTATGATTAACTTTAATGATCCTCTTGACCTCGAAAAAAAGGTTTCAGAGAGAAC
CGCCGCTGTTTTTATAGAAATCATCCAGGGTGAGGGTGGGATTCACCAGATATCAGCGCCGTTTATTGAAAAGCTCAATG
AACTGCGCCAACGCCATAATTTTTTAATCGTTGCCGATGAGATTCAGGCTGGATGCGGAAGAACCGGCAAGTTTTTCAGT
TACCTGCATTTTGATTTCGAACCTGATCTGGTTTGCCTTGCCAAACCGCTGGGAGGAGGTCTGCCCTTATCAGCAGTTCT
CGGCAGCGAGAGCCTTTCCGATGTGTTCAGTTACGGAAACCATGGTACGACCTTCGGGGGCAATCCTGTCGCCTGTGCAG
CAGGCCTGGCGATGATTGAGGCGATCTATGAGGACAATCTCATGGCACATGCTGTAGAGATCGGCAGCTTTATTAAAACC
GGATTGCTGCAACTCGCACAAAAGCACTCACAAATAACAGCGATACGGCAGTATGGATTAATGATCGGCATGACAGTCGA
CAAAGAAGCGAAGTTCTATGTTGAAAAAGCTCTTAAGAAGCATGTCATTATAAATGCAACAAGCCAAAACGTTATCCGGC
TTCTGCCTCCACTCAACATCAGCCAGGGGGAAGCTCAACAATGTATCATGGTTCTTGATGAAATCTTTAACGAAGAATAA

Upstream 100 bases:

>100_bases
GAAAAAAAAGTTTGAACGCATGACGAATCATCATTATTATCACCTTTTTTAGTGACTGGCTGAACATTCTCCACAGACAC
CTTTACCAAGAGAACGTTAC

Downstream 100 bases:

>100_bases
AAGAGTTAAACCTGCGGATAAAAAAGGACTCAAGCAGACAGCAATGCCTCTGGGAGTCATAAACTACAGTATGATTGCCT
TAGGCGTCCTGGTTATTGCC

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNMKQMPITPESEQALFFHNYARLPIAITHGDGSWLVSDTGIRYLDMIAGIGVNALGYGDKRLINAINEQAAKIIHASNL
FLLQPQFALAEKLLEISGLSKVFFANSGTEAIEASIKMARKWAASSGNDRKKEILSLSNCFHGRTYGAMSLTAKAKYTDG
FEPLLPDTGMINFNDPLDLEKKVSERTAAVFIEIIQGEGGIHQISAPFIEKLNELRQRHNFLIVADEIQAGCGRTGKFFS
YLHFDFEPDLVCLAKPLGGGLPLSAVLGSESLSDVFSYGNHGTTFGGNPVACAAGLAMIEAIYEDNLMAHAVEIGSFIKT
GLLQLAQKHSQITAIRQYGLMIGMTVDKEAKFYVEKALKKHVIINATSQNVIRLLPPLNISQGEAQQCIMVLDEIFNEE

Sequences:

>Translated_399_residues
MNMKQMPITPESEQALFFHNYARLPIAITHGDGSWLVSDTGIRYLDMIAGIGVNALGYGDKRLINAINEQAAKIIHASNL
FLLQPQFALAEKLLEISGLSKVFFANSGTEAIEASIKMARKWAASSGNDRKKEILSLSNCFHGRTYGAMSLTAKAKYTDG
FEPLLPDTGMINFNDPLDLEKKVSERTAAVFIEIIQGEGGIHQISAPFIEKLNELRQRHNFLIVADEIQAGCGRTGKFFS
YLHFDFEPDLVCLAKPLGGGLPLSAVLGSESLSDVFSYGNHGTTFGGNPVACAAGLAMIEAIYEDNLMAHAVEIGSFIKT
GLLQLAQKHSQITAIRQYGLMIGMTVDKEAKFYVEKALKKHVIINATSQNVIRLLPPLNISQGEAQQCIMVLDEIFNEE
>Mature_399_residues
MNMKQMPITPESEQALFFHNYARLPIAITHGDGSWLVSDTGIRYLDMIAGIGVNALGYGDKRLINAINEQAAKIIHASNL
FLLQPQFALAEKLLEISGLSKVFFANSGTEAIEASIKMARKWAASSGNDRKKEILSLSNCFHGRTYGAMSLTAKAKYTDG
FEPLLPDTGMINFNDPLDLEKKVSERTAAVFIEIIQGEGGIHQISAPFIEKLNELRQRHNFLIVADEIQAGCGRTGKFFS
YLHFDFEPDLVCLAKPLGGGLPLSAVLGSESLSDVFSYGNHGTTFGGNPVACAAGLAMIEAIYEDNLMAHAVEIGSFIKT
GLLQLAQKHSQITAIRQYGLMIGMTVDKEAKFYVEKALKKHVIINATSQNVIRLLPPLNISQGEAQQCIMVLDEIFNEE

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=392, Percent_Identity=31.6326530612245, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI284507298, Length=297, Percent_Identity=33.6700336700337, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI13994255, Length=372, Percent_Identity=29.8387096774194, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI37574042, Length=421, Percent_Identity=27.3159144893112, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI24119277, Length=416, Percent_Identity=26.6826923076923, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226442705, Length=421, Percent_Identity=27.5534441805226, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI226442709, Length=341, Percent_Identity=29.0322580645161, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI188536080, Length=451, Percent_Identity=23.9467849223947, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI38679950, Length=451, Percent_Identity=23.9467849223947, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI38679946, Length=451, Percent_Identity=23.9467849223947, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1788044, Length=382, Percent_Identity=36.9109947643979, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1789759, Length=388, Percent_Identity=33.5051546391753, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI145693181, Length=381, Percent_Identity=34.3832020997375, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1789016, Length=396, Percent_Identity=30.5555555555556, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1787560, Length=389, Percent_Identity=31.1053984575836, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1786991, Length=308, Percent_Identity=30.5194805194805, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1786349, Length=342, Percent_Identity=24.2690058479532, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25144271, Length=383, Percent_Identity=28.7206266318538, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI32564660, Length=434, Percent_Identity=28.3410138248848, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71992977, Length=431, Percent_Identity=26.2180974477958, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI25144274, Length=263, Percent_Identity=29.277566539924, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71981843, Length=167, Percent_Identity=26.3473053892216, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17541228, Length=360, Percent_Identity=24.1666666666667, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324432, Length=385, Percent_Identity=33.2467532467532, Blast_Score=218, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=33.4987593052109, Blast_Score=199, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6324386, Length=473, Percent_Identity=24.1014799154334, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6321456, Length=279, Percent_Identity=28.673835125448, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21357415, Length=380, Percent_Identity=29.7368421052632, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI28574759, Length=423, Percent_Identity=31.4420803782506, Blast_Score=185, Evalue=6e-47,
Organism=Drosophila melanogaster, GI161085790, Length=427, Percent_Identity=30.9133489461358, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI21356575, Length=427, Percent_Identity=25.7611241217799, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281366494, Length=420, Percent_Identity=26.4285714285714, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24667139, Length=420, Percent_Identity=26.4285714285714, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24667143, Length=420, Percent_Identity=26.4285714285714, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43672; Mature: 43672

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMKQMPITPESEQALFFHNYARLPIAITHGDGSWLVSDTGIRYLDMIAGIGVNALGYGD
CCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCEEEECCCHHHHHHHHCCCCCCCCCCH
KRLINAINEQAAKIIHASNLFLLQPQFALAEKLLEISGLSKVFFANSGTEAIEASIKMAR
HHHHHHHHHHHHHHHEECCEEEECCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
KWAASSGNDRKKEILSLSNCFHGRTYGAMSLTAKAKYTDGFEPLLPDTGMINFNDPLDLE
HHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCHH
KKVSERTAAVFIEIIQGEGGIHQISAPFIEKLNELRQRHNFLIVADEIQAGCGRTGKFFS
HHHHHHHHHHEEEEEECCCCCEECCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEE
YLHFDFEPDLVCLAKPLGGGLPLSAVLGSESLSDVFSYGNHGTTFGGNPVACAAGLAMIE
EEEECCCCCEEEEECCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AIYEDNLMAHAVEIGSFIKTGLLQLAQKHSQITAIRQYGLMIGMTVDKEAKFYVEKALKK
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHC
HVIINATSQNVIRLLPPLNISQGEAQQCIMVLDEIFNEE
CEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNMKQMPITPESEQALFFHNYARLPIAITHGDGSWLVSDTGIRYLDMIAGIGVNALGYGD
CCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCEEEECCCHHHHHHHHCCCCCCCCCCH
KRLINAINEQAAKIIHASNLFLLQPQFALAEKLLEISGLSKVFFANSGTEAIEASIKMAR
HHHHHHHHHHHHHHHEECCEEEECCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
KWAASSGNDRKKEILSLSNCFHGRTYGAMSLTAKAKYTDGFEPLLPDTGMINFNDPLDLE
HHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCHH
KKVSERTAAVFIEIIQGEGGIHQISAPFIEKLNELRQRHNFLIVADEIQAGCGRTGKFFS
HHHHHHHHHHEEEEEECCCCCEECCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEE
YLHFDFEPDLVCLAKPLGGGLPLSAVLGSESLSDVFSYGNHGTTFGGNPVACAAGLAMIE
EEEECCCCCEEEEECCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AIYEDNLMAHAVEIGSFIKTGLLQLAQKHSQITAIRQYGLMIGMTVDKEAKFYVEKALKK
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHC
HVIINATSQNVIRLLPPLNISQGEAQQCIMVLDEIFNEE
CEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]