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The map label for this gene is lolC [H]

Identifier: 119356426

GI number: 119356426

Start: 660615

End: 661889

Strand: Direct

Name: lolC [H]

Synonym: Cpha266_0590

Alternate gene names: 119356426

Gene position: 660615-661889 (Clockwise)

Preceding gene: 119356422

Following gene: 119356428

Centisome position: 21.08

GC content: 46.9

Gene sequence:

>1275_bases
ATGACACTCTTTGATCAGATCAGAATTGCTTATGTCCATCTCAAAGAGCGCAAAAGGCAGACAATGCTTACTGCTCTCGG
AGTTGCTGTTGGTTCGGCGATGCTTGTGACTACTATTTCCGTTGCGCGCGGTTCATCTTCAAACGTTATTACCAAGGTGA
TTGATACGGCTCCGCATGTTCTGGTCAGCGCTGACAGGATAGAGCCGCTTGTGCCGGAAAATCTCATAGGCTATAGTTCT
TCACGAGTCGCAATGGTGACAAGGAATGTCACCTCCAATGACAAGGAGGTCATCAAGAATTACACGGAGGTGGTAGAGAA
TATCAGAAAAATCAAAGGTCTGGAAAGTATTTCCCCGTTTGTGCTCAGCAAGGTTCTGGCCAGAAACAAATCACGTTTTA
CTTCCTGTATTGCCCGGGGAGTTTCTCCTCCCCTTGAAGCAGATATTGCCGGGTTGAAAAAGAATCTTATTGAGAAAAAT
GCTCTTGAGGAGCTTGCTTATACACCGGACGGAATTCTTGTGGGTTATTTGCTTGCTGAAAAACTCGATGCGGGTTACCA
CGATCGTATTGTGCTGGTAACAAAGAACAGCGAATCATATCCAGTGACGATTGTCGGGAGTTTCAGCAGCGGATTTAATG
CCAAGGATGAACGTGAGGCATATGTCAATCTTGCCCTTGCGCAGAGAATGGAAGGCATCGCTGCCAATTCTGTTAGCGGG
ATTGGTTTGAGAACTTCTGACGTCAATCGTGCTTCAGGCGTCGCTGCCCAGGTTGCCGATATAACCGGGTACAAAAGTGA
AAGCTGGGATGAAACAAATCGTAACGTGATCGATTTCTATAACCGTAATGCGGTTATTACCCTTGTTCTTGTTGGTTTTG
TTTTTGTTGTCGCCGGTCTCGGAGTCTCTTCCGTGATGACTACGGTGGTACTGCAGAAGGTCAAGGATATTGCTATTCTG
CGTTCAATGGGGCTGCAACGCGAGAGCATTACCCGAATATTTATGTTTGAAGGTCTCTTTATCGGTATTCTCGGGGTATT
GATAGGAAGTCCGGCAGGGCATGCTATCTGTCATTTTGTCTCGATGATCCGTTTTGAAGCCAGTACTGCCGGCGTGCTGA
AAAGCGACCGCATCAATCTTGTTGAAACACCTGAGGCGCATCTTATTGTCATCGTGTTTGGTGTTCTTATTGCCGTAATT
TCATCATTCAGCCCGGCAAGAAAGGCGACCAGTTATCTTCCGGTAAGTATTTTGCGCGGCGAGGTCGGCGCTTAG

Upstream 100 bases:

>100_bases
CTCCGGCACTCAAGATAGATTTTTTGTGAGATTTTTCAACGTAGTGTGGCAAAAATCCCTCGATGCCTTCCTTTATCGAT
AAATTTTGTTCATTGGTTTT

Downstream 100 bases:

>100_bases
GGCTTTACCTGAATAAGGCAGACGGCATGAGCTGCGGCGCCTTCTTCTCTGCCGATGTAGCCGAGCTTTTCGTTTGTTGT
TGCTTTCACCGATACGGCAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MTLFDQIRIAYVHLKERKRQTMLTALGVAVGSAMLVTTISVARGSSSNVITKVIDTAPHVLVSADRIEPLVPENLIGYSS
SRVAMVTRNVTSNDKEVIKNYTEVVENIRKIKGLESISPFVLSKVLARNKSRFTSCIARGVSPPLEADIAGLKKNLIEKN
ALEELAYTPDGILVGYLLAEKLDAGYHDRIVLVTKNSESYPVTIVGSFSSGFNAKDEREAYVNLALAQRMEGIAANSVSG
IGLRTSDVNRASGVAAQVADITGYKSESWDETNRNVIDFYNRNAVITLVLVGFVFVVAGLGVSSVMTTVVLQKVKDIAIL
RSMGLQRESITRIFMFEGLFIGILGVLIGSPAGHAICHFVSMIRFEASTAGVLKSDRINLVETPEAHLIVIVFGVLIAVI
SSFSPARKATSYLPVSILRGEVGA

Sequences:

>Translated_424_residues
MTLFDQIRIAYVHLKERKRQTMLTALGVAVGSAMLVTTISVARGSSSNVITKVIDTAPHVLVSADRIEPLVPENLIGYSS
SRVAMVTRNVTSNDKEVIKNYTEVVENIRKIKGLESISPFVLSKVLARNKSRFTSCIARGVSPPLEADIAGLKKNLIEKN
ALEELAYTPDGILVGYLLAEKLDAGYHDRIVLVTKNSESYPVTIVGSFSSGFNAKDEREAYVNLALAQRMEGIAANSVSG
IGLRTSDVNRASGVAAQVADITGYKSESWDETNRNVIDFYNRNAVITLVLVGFVFVVAGLGVSSVMTTVVLQKVKDIAIL
RSMGLQRESITRIFMFEGLFIGILGVLIGSPAGHAICHFVSMIRFEASTAGVLKSDRINLVETPEAHLIVIVFGVLIAVI
SSFSPARKATSYLPVSILRGEVGA
>Mature_423_residues
TLFDQIRIAYVHLKERKRQTMLTALGVAVGSAMLVTTISVARGSSSNVITKVIDTAPHVLVSADRIEPLVPENLIGYSSS
RVAMVTRNVTSNDKEVIKNYTEVVENIRKIKGLESISPFVLSKVLARNKSRFTSCIARGVSPPLEADIAGLKKNLIEKNA
LEELAYTPDGILVGYLLAEKLDAGYHDRIVLVTKNSESYPVTIVGSFSSGFNAKDEREAYVNLALAQRMEGIAANSVSGI
GLRTSDVNRASGVAAQVADITGYKSESWDETNRNVIDFYNRNAVITLVLVGFVFVVAGLGVSSVMTTVVLQKVKDIAILR
SMGLQRESITRIFMFEGLFIGILGVLIGSPAGHAICHFVSMIRFEASTAGVLKSDRINLVETPEAHLIVIVFGVLIAVIS
SFSPARKATSYLPVSILRGEVGA

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=420, Percent_Identity=22.3809523809524, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45791; Mature: 45660

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLFDQIRIAYVHLKERKRQTMLTALGVAVGSAMLVTTISVARGSSSNVITKVIDTAPHV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
LVSADRIEPLVPENLIGYSSSRVAMVTRNVTSNDKEVIKNYTEVVENIRKIKGLESISPF
EEECCCCCCCCCCHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHCCHH
VLSKVLARNKSRFTSCIARGVSPPLEADIAGLKKNLIEKNALEELAYTPDGILVGYLLAE
HHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KLDAGYHDRIVLVTKNSESYPVTIVGSFSSGFNAKDEREAYVNLALAQRMEGIAANSVSG
HHCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCHHCCCCCC
IGLRTSDVNRASGVAAQVADITGYKSESWDETNRNVIDFYNRNAVITLVLVGFVFVVAGL
CCEECCCCCHHCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHC
GVSSVMTTVVLQKVKDIAILRSMGLQRESITRIFMFEGLFIGILGVLIGSPAGHAICHFV
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SMIRFEASTAGVLKSDRINLVETPEAHLIVIVFGVLIAVISSFSPARKATSYLPVSILRG
HHHHHHCHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCC
EVGA
CCCC
>Mature Secondary Structure 
TLFDQIRIAYVHLKERKRQTMLTALGVAVGSAMLVTTISVARGSSSNVITKVIDTAPHV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
LVSADRIEPLVPENLIGYSSSRVAMVTRNVTSNDKEVIKNYTEVVENIRKIKGLESISPF
EEECCCCCCCCCCHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHCCHH
VLSKVLARNKSRFTSCIARGVSPPLEADIAGLKKNLIEKNALEELAYTPDGILVGYLLAE
HHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KLDAGYHDRIVLVTKNSESYPVTIVGSFSSGFNAKDEREAYVNLALAQRMEGIAANSVSG
HHCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCHHCCCCCC
IGLRTSDVNRASGVAAQVADITGYKSESWDETNRNVIDFYNRNAVITLVLVGFVFVVAGL
CCEECCCCCHHCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHC
GVSSVMTTVVLQKVKDIAILRSMGLQRESITRIFMFEGLFIGILGVLIGSPAGHAICHFV
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SMIRFEASTAGVLKSDRINLVETPEAHLIVIVFGVLIAVISSFSPARKATSYLPVSILRG
HHHHHHCHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCC
EVGA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]