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The map label for this gene is ywlC [H]

Identifier: 119356333

GI number: 119356333

Start: 543798

End: 544769

Strand: Reverse

Name: ywlC [H]

Synonym: Cpha266_0496

Alternate gene names: 119356333

Gene position: 544769-543798 (Counterclockwise)

Preceding gene: 119356334

Following gene: 119356327

Centisome position: 17.38

GC content: 52.16

Gene sequence:

>972_bases
ATGCAGACACTGCTCACCGACTCACCCGAAGAGGCTGCCCGGATAATCAATCAGGGAAACATCGTCGCCTTTCCTACCGA
AACCGTTTATGGGCTTGGCGCAGCCATCTGCTTTCCCGAAGCTGTTAAAAAACTTTTTCTGGCAAAAGGACGTCCGACAG
ATAATCCCCTTATCGTGCATATCCACAATGCCGGAGAGATGTCAAAAGTCGCATCGGAGATATCACCGGAAGCAACCCTG
CTCATTGAACATTTTTTTCCGGGGCCCCTCACGCTTGTCCTGAAAAAAAAGGCAACCGTACCGGATGCGGTTACGGCCGG
GCTTGACACGGTCGGAGTCAGATGCCCTGAAAATCAGATTGCACGGGCATTTCTCCGCCATTGCTGCGCTCCTGTAGCCG
CGCCTTCAGCAAACCTTTCCGGCAAACCAAGCTCCACCACGTGGGAAGCGGTCTTTCATGATCTGAACGGTAAAATACCC
TGCATTCTCAGGGGAGAACCCTCTATTGTCGGGCTTGAATCCACGATTGTCGACTGTTCTGAACACGAACCCATACTGCT
TCGTGAAGGAGCTGTGACGCTTGAAGAGCTTCAGCGGATACTTCCAGCGATGAAAGCGCGAAAAACCGGGATGAAGGACG
AAAAACCGAAAAGCCCTGGGCTGAAATATCCCCACTATGCACCAAAAGCAGCCATCAGACTCTGCCGCAGGGGAGAACGA
CCTCCAGAGAGCACTCTATCCTCAGCCTATATCGGTTTATCGAATCCTCCTGAAGGCATCCGTATGGTGAGCATCTGCCA
GAGCATTGAAGAGTATGCAAGATCCCTGTTCAGCTTTTTTCGTGCCTGTGACCGCGAGGGAATCAGCGTGATCTATTGTG
AACTGCCGGAACAAAAAGGGTTGGGACGGGCAATTCACGACCGGCTTATGCGGGCATCGGGCGAACATGAGAGTAAAAAT
GGCACCACCTAA

Upstream 100 bases:

>100_bases
CCCTGTTGAGCGCTTCGACGGGATGGGTCACCTACCTGCTATTTCTGCCTCTTCAAATTGAAGCGCTCTCTTTTTGTCGT
TAGCTATCTTTTGTAAACCC

Downstream 100 bases:

>100_bases
AATCTCAGTGAACACCCGAGTGTAACGGTGCCGGGAGCGCTGGTATCCCGCTGATCAGCGCCTGAACTGAACACAGCTCT
GTCTGTGTACCAGGCTACCT

Product: translation factor SUA5

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MQTLLTDSPEEAARIINQGNIVAFPTETVYGLGAAICFPEAVKKLFLAKGRPTDNPLIVHIHNAGEMSKVASEISPEATL
LIEHFFPGPLTLVLKKKATVPDAVTAGLDTVGVRCPENQIARAFLRHCCAPVAAPSANLSGKPSSTTWEAVFHDLNGKIP
CILRGEPSIVGLESTIVDCSEHEPILLREGAVTLEELQRILPAMKARKTGMKDEKPKSPGLKYPHYAPKAAIRLCRRGER
PPESTLSSAYIGLSNPPEGIRMVSICQSIEEYARSLFSFFRACDREGISVIYCELPEQKGLGRAIHDRLMRASGEHESKN
GTT

Sequences:

>Translated_323_residues
MQTLLTDSPEEAARIINQGNIVAFPTETVYGLGAAICFPEAVKKLFLAKGRPTDNPLIVHIHNAGEMSKVASEISPEATL
LIEHFFPGPLTLVLKKKATVPDAVTAGLDTVGVRCPENQIARAFLRHCCAPVAAPSANLSGKPSSTTWEAVFHDLNGKIP
CILRGEPSIVGLESTIVDCSEHEPILLREGAVTLEELQRILPAMKARKTGMKDEKPKSPGLKYPHYAPKAAIRLCRRGER
PPESTLSSAYIGLSNPPEGIRMVSICQSIEEYARSLFSFFRACDREGISVIYCELPEQKGLGRAIHDRLMRASGEHESKN
GTT
>Mature_323_residues
MQTLLTDSPEEAARIINQGNIVAFPTETVYGLGAAICFPEAVKKLFLAKGRPTDNPLIVHIHNAGEMSKVASEISPEATL
LIEHFFPGPLTLVLKKKATVPDAVTAGLDTVGVRCPENQIARAFLRHCCAPVAAPSANLSGKPSSTTWEAVFHDLNGKIP
CILRGEPSIVGLESTIVDCSEHEPILLREGAVTLEELQRILPAMKARKTGMKDEKPKSPGLKYPHYAPKAAIRLCRRGER
PPESTLSSAYIGLSNPPEGIRMVSICQSIEEYARSLFSFFRACDREGISVIYCELPEQKGLGRAIHDRLMRASGEHESKN
GTT

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=181, Percent_Identity=29.2817679558011, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367210, Length=166, Percent_Identity=28.9156626506024, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081864, Length=193, Percent_Identity=25.3886010362694, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17537239, Length=204, Percent_Identity=30.3921568627451, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321269, Length=369, Percent_Identity=33.6043360433604, Blast_Score=164, Evalue=1e-41,
Organism=Drosophila melanogaster, GI78707274, Length=135, Percent_Identity=31.8518518518519, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 35132; Mature: 35132

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLLTDSPEEAARIINQGNIVAFPTETVYGLGAAICFPEAVKKLFLAKGRPTDNPLIVH
CCCCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
IHNAGEMSKVASEISPEATLLIEHFFPGPLTLVLKKKATVPDAVTAGLDTVGVRCPENQI
EECCCHHHHHHHHCCCCCEEEEEHHCCCCEEEEEECCCCCCHHHHHCCHHCCCCCCHHHH
ARAFLRHCCAPVAAPSANLSGKPSSTTWEAVFHDLNGKIPCILRGEPSIVGLESTIVDCS
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCEEECHHHEECCC
EHEPILLREGAVTLEELQRILPAMKARKTGMKDEKPKSPGLKYPHYAPKAAIRLCRRGER
CCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
PPESTLSSAYIGLSNPPEGIRMVSICQSIEEYARSLFSFFRACDREGISVIYCELPEQKG
CCHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
LGRAIHDRLMRASGEHESKNGTT
CCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQTLLTDSPEEAARIINQGNIVAFPTETVYGLGAAICFPEAVKKLFLAKGRPTDNPLIVH
CCCCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
IHNAGEMSKVASEISPEATLLIEHFFPGPLTLVLKKKATVPDAVTAGLDTVGVRCPENQI
EECCCHHHHHHHHCCCCCEEEEEHHCCCCEEEEEECCCCCCHHHHHCCHHCCCCCCHHHH
ARAFLRHCCAPVAAPSANLSGKPSSTTWEAVFHDLNGKIPCILRGEPSIVGLESTIVDCS
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCEEECHHHEECCC
EHEPILLREGAVTLEELQRILPAMKARKTGMKDEKPKSPGLKYPHYAPKAAIRLCRRGER
CCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
PPESTLSSAYIGLSNPPEGIRMVSICQSIEEYARSLFSFFRACDREGISVIYCELPEQKG
CCHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
LGRAIHDRLMRASGEHESKNGTT
CCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]