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The map label for this gene is lolC [H]

Identifier: 119356225

GI number: 119356225

Start: 426500

End: 427768

Strand: Direct

Name: lolC [H]

Synonym: Cpha266_0386

Alternate gene names: 119356225

Gene position: 426500-427768 (Clockwise)

Preceding gene: 119356221

Following gene: 119356228

Centisome position: 13.61

GC content: 47.83

Gene sequence:

>1269_bases
ATGCTGAAAACACTGTTTGATATCGCGTTGCGTCATCTGCTCGGCCGCCGTCGCCAGACTTTGACCACGATTTTTGGCGT
TGCGGTAAGTACCATGGTGCTTATTACCACCATATCCCTGACCAGAGGCCTGCTTGATTCGTTTATTGATACCATTGTCA
ATGTGGCGCCCCATATAACCATCAAAGGCGAAAAACTCAATCCTGTGCCGGTTAATATCATTAATCGTGCAGGGGAGACG
CGGGTTTCCATGGTTGAGGACAATATCAGGAAGCAGGAAAAGGAAGAGGTAAGGAATTATCGCCAGATTCTCGGTATGTT
CAGCTCTTCCCTGTATGAAAAAGAGGTGACCGCGTCTTCACCGTATGTCGAGTCGCAGGTTATGGCGGTTAAGGGCAACA
GGAATCAGCCGATTTTGCTCAAGGGTGTTATTATTGACAGGGAAAATGAAATCAGCGGGATTGCGGGGAAGATTCAGCAA
GGAGATCTTTCAGTCTTTCGCAACTCCTCAAACGCGCTTCTTGTTGGACGAACGGTTGCCCGTGACATGCATCTGGAGCT
CAATGATGAGGTCGTCATTATTCCTGCATCGGGAAAAAGCAGGCAGTGCAAAGTTGCCGGAATATTTTTTTCCGGAGTCA
ATGCCGTTGATAACAGCGTGTTTGTTTCGCTCAAGCTTGGCCAGATCATCGAGGGACTGCCCGCCAACAAGGTGAGTGGT
ATTGCGCTCAAGGTCAGGGATCCGCTGAACAATACCCCTCTTGCAAGAGAGATGGAAAGGATTACCGGATACAAATGTCC
TACCTGGCAGGAAGAGAATGCGAGCATTCTATCCCTTTTTGCCCGTATCGGCTATATCGTTTTTTCTCTTGTGGCATTTG
TCGGCGTTGTGTCGGGATTCGGCGTCGCCAATATTCTGGTTACTACGGTGTTTGAAAAAAGTCGCGATATAGCCATCATG
AAATCGTTTGGATTTTCCGCTTTACATCTGGTGGCGATGTTTGTACTTGAAGGTTTTCTTGTAGGGTTGGCCGGAGCGCT
TCTTGGTGGCGTTCTCGCCATTGGTTCCATTAATCTTTTTGCAAGCATTCCTGTCGAAAATTCCCAGGGGCCGCTGACCA
AGACAGGTTTCAGTATGTCCCTTAACCCGATCTATTTTTTTTATGTTATCGGTGTGACGGTCTTTATCAGTACGATTTCA
GCAATTCTCCCTTCTGCAAGGGCAGCAAAGCTTGAACCGGTAAAGGTGCTGCGCGACAGCAGTTTATAA

Upstream 100 bases:

>100_bases
TCAGATCGCCTGTTTCTGTGAAGGAGTTGCCTTACTGATAGTTAAAGATGTAACTTAATAAAAATATCCCAACTTTTTAG
TTTGCCCGTAAACAGCCATC

Downstream 100 bases:

>100_bases
AAGAGAGGGATTTAAAGGAGCAACAGTACCCAGGGCAAGAAAGAACGAGAGGGGAACAAGATCATTTTTGTTTCGATTCA
TTCATGAACTCCTTTTCTTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MLKTLFDIALRHLLGRRRQTLTTIFGVAVSTMVLITTISLTRGLLDSFIDTIVNVAPHITIKGEKLNPVPVNIINRAGET
RVSMVEDNIRKQEKEEVRNYRQILGMFSSSLYEKEVTASSPYVESQVMAVKGNRNQPILLKGVIIDRENEISGIAGKIQQ
GDLSVFRNSSNALLVGRTVARDMHLELNDEVVIIPASGKSRQCKVAGIFFSGVNAVDNSVFVSLKLGQIIEGLPANKVSG
IALKVRDPLNNTPLAREMERITGYKCPTWQEENASILSLFARIGYIVFSLVAFVGVVSGFGVANILVTTVFEKSRDIAIM
KSFGFSALHLVAMFVLEGFLVGLAGALLGGVLAIGSINLFASIPVENSQGPLTKTGFSMSLNPIYFFYVIGVTVFISTIS
AILPSARAAKLEPVKVLRDSSL

Sequences:

>Translated_422_residues
MLKTLFDIALRHLLGRRRQTLTTIFGVAVSTMVLITTISLTRGLLDSFIDTIVNVAPHITIKGEKLNPVPVNIINRAGET
RVSMVEDNIRKQEKEEVRNYRQILGMFSSSLYEKEVTASSPYVESQVMAVKGNRNQPILLKGVIIDRENEISGIAGKIQQ
GDLSVFRNSSNALLVGRTVARDMHLELNDEVVIIPASGKSRQCKVAGIFFSGVNAVDNSVFVSLKLGQIIEGLPANKVSG
IALKVRDPLNNTPLAREMERITGYKCPTWQEENASILSLFARIGYIVFSLVAFVGVVSGFGVANILVTTVFEKSRDIAIM
KSFGFSALHLVAMFVLEGFLVGLAGALLGGVLAIGSINLFASIPVENSQGPLTKTGFSMSLNPIYFFYVIGVTVFISTIS
AILPSARAAKLEPVKVLRDSSL
>Mature_422_residues
MLKTLFDIALRHLLGRRRQTLTTIFGVAVSTMVLITTISLTRGLLDSFIDTIVNVAPHITIKGEKLNPVPVNIINRAGET
RVSMVEDNIRKQEKEEVRNYRQILGMFSSSLYEKEVTASSPYVESQVMAVKGNRNQPILLKGVIIDRENEISGIAGKIQQ
GDLSVFRNSSNALLVGRTVARDMHLELNDEVVIIPASGKSRQCKVAGIFFSGVNAVDNSVFVSLKLGQIIEGLPANKVSG
IALKVRDPLNNTPLAREMERITGYKCPTWQEENASILSLFARIGYIVFSLVAFVGVVSGFGVANILVTTVFEKSRDIAIM
KSFGFSALHLVAMFVLEGFLVGLAGALLGGVLAIGSINLFASIPVENSQGPLTKTGFSMSLNPIYFFYVIGVTVFISTIS
AILPSARAAKLEPVKVLRDSSL

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=424, Percent_Identity=24.5283018867925, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45833; Mature: 45833

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTLFDIALRHLLGRRRQTLTTIFGVAVSTMVLITTISLTRGLLDSFIDTIVNVAPHIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IKGEKLNPVPVNIINRAGETRVSMVEDNIRKQEKEEVRNYRQILGMFSSSLYEKEVTASS
EECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PYVESQVMAVKGNRNQPILLKGVIIDRENEISGIAGKIQQGDLSVFRNSSNALLVGRTVA
CCCCCEEEEEECCCCCCEEEEEEEEECCCCCCCHHCCCCCCCHHEEECCCCEEEEEHHHH
RDMHLELNDEVVIIPASGKSRQCKVAGIFFSGVNAVDNSVFVSLKLGQIIEGLPANKVSG
HCEEEEECCCEEEEECCCCCCEEEEEEEEEECCCCCCCCEEEEEEHHHHHCCCCCCCCCC
IALKVRDPLNNTPLAREMERITGYKCPTWQEENASILSLFARIGYIVFSLVAFVGVVSGF
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVANILVTTVFEKSRDIAIMKSFGFSALHLVAMFVLEGFLVGLAGALLGGVLAIGSINLF
CHHHHHHHHHHHCCCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
ASIPVENSQGPLTKTGFSMSLNPIYFFYVIGVTVFISTISAILPSARAAKLEPVKVLRDS
EECCCCCCCCCCEECCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC
SL
CC
>Mature Secondary Structure
MLKTLFDIALRHLLGRRRQTLTTIFGVAVSTMVLITTISLTRGLLDSFIDTIVNVAPHIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IKGEKLNPVPVNIINRAGETRVSMVEDNIRKQEKEEVRNYRQILGMFSSSLYEKEVTASS
EECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PYVESQVMAVKGNRNQPILLKGVIIDRENEISGIAGKIQQGDLSVFRNSSNALLVGRTVA
CCCCCEEEEEECCCCCCEEEEEEEEECCCCCCCHHCCCCCCCHHEEECCCCEEEEEHHHH
RDMHLELNDEVVIIPASGKSRQCKVAGIFFSGVNAVDNSVFVSLKLGQIIEGLPANKVSG
HCEEEEECCCEEEEECCCCCCEEEEEEEEEECCCCCCCCEEEEEEHHHHHCCCCCCCCCC
IALKVRDPLNNTPLAREMERITGYKCPTWQEENASILSLFARIGYIVFSLVAFVGVVSGF
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVANILVTTVFEKSRDIAIMKSFGFSALHLVAMFVLEGFLVGLAGALLGGVLAIGSINLF
CHHHHHHHHHHHCCCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
ASIPVENSQGPLTKTGFSMSLNPIYFFYVIGVTVFISTISAILPSARAAKLEPVKVLRDS
EECCCCCCCCCCEECCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC
SL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]