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The map label for this gene is idsA [H]

Identifier: 119356223

GI number: 119356223

Start: 424300

End: 425298

Strand: Reverse

Name: idsA [H]

Synonym: Cpha266_0384

Alternate gene names: 119356223

Gene position: 425298-424300 (Counterclockwise)

Preceding gene: 119356224

Following gene: 119356222

Centisome position: 13.57

GC content: 47.15

Gene sequence:

>999_bases
ATGAACATGTCTATCACACAGGAACTTGTCGAAAAAAAGTATCGCCTCTACCACAACCTTATCAATGAAGCTCTCGCAAG
CTGCTTCAGCGCCGAAGCCCCGGTAACACTGTACGCTCCGGCCAAGTATATTCTTGATGGAAAAGGGAAAAGAATCAGAC
CGTTTCTGACTCTTCTTGCTTCCGAAGCTGTTTGTGGTTCATCTGAACACGCACTCAAGGTTGCGCTTGCTGTCGAGATT
CTCCATAATTTCACCTTGATGCATGATGATATCATGGATCAGGCTGAACTTCGCCATGGCAGACCAACCGTACACAAACA
GTGGAATGCCAATGTAGCAATCCTTTCAGGCGATATGATGATTGCCTACGCCTATGAGCTTGCCCTCCAATCCCCATCTT
CACGACAAATTGAGCTGGTGCATATCCTTAATGATGCAAATATAACCATTTGTGAAGGTCAGGCTCTCGACATCGAACTG
GAGGAGAAAAAACACGCTACCATTGCCGATTATCTTGACATGATTGCAAAAAAATCCGGCAGACTCATATCGGCAGCTCT
CGAAGCAGGGGGTGTTGCCGGCAATGCCACTGATGAACAGCTCAACAACCTGGTGACCTTCGGTGAAAAAATCGGCAGGG
CATTTCAGATACAGGATGACTTTCTTGACATTATGGCTGATGACGGGAAGTCAGGAAAGATTGCCGGGGGCGATGTCATC
AACGGCAAAAAAACCTATCTCCTTCTGCGATCAATCGAGCTTACTTCCGGAGATGATCACCGTCTGCTGCAATCAATTAT
TGAAAATAACGGCATCAGCGCCGAAAGGGTACCCGAAATCCGGTCAATCTATCAACGATGCGGCGTGCTTGACGAAACAA
GACTCCTGATTCGACGCGACACCGAAAATGCACTGTCGGCAGTGGACAAACTGCCACATGCCGAAGGCCGTGAATACCTC
AAAGGTTTTGCAAACATCCTTGTAAAAAGGGATTTTTAA

Upstream 100 bases:

>100_bases
GGCTGAACGACCTCAAGGCGGTGATGTTTCTTACCGGCTCTCTCTCTCTGGAACAGCTTCAAAAAAAACGCATGACTCTT
AAACATCTTCCGACTTAGTA

Downstream 100 bases:

>100_bases
TTGCTGAGAAAGGCATGAGCGCCACTCCCGGATGTGATTCGAGAATTCTCCTGCTGACCCTGTCGCAGATCCCCGGCATC
GGCCCGGCAAGGATCAATGC

Product: polyprenyl synthetase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNMSITQELVEKKYRLYHNLINEALASCFSAEAPVTLYAPAKYILDGKGKRIRPFLTLLASEAVCGSSEHALKVALAVEI
LHNFTLMHDDIMDQAELRHGRPTVHKQWNANVAILSGDMMIAYAYELALQSPSSRQIELVHILNDANITICEGQALDIEL
EEKKHATIADYLDMIAKKSGRLISAALEAGGVAGNATDEQLNNLVTFGEKIGRAFQIQDDFLDIMADDGKSGKIAGGDVI
NGKKTYLLLRSIELTSGDDHRLLQSIIENNGISAERVPEIRSIYQRCGVLDETRLLIRRDTENALSAVDKLPHAEGREYL
KGFANILVKRDF

Sequences:

>Translated_332_residues
MNMSITQELVEKKYRLYHNLINEALASCFSAEAPVTLYAPAKYILDGKGKRIRPFLTLLASEAVCGSSEHALKVALAVEI
LHNFTLMHDDIMDQAELRHGRPTVHKQWNANVAILSGDMMIAYAYELALQSPSSRQIELVHILNDANITICEGQALDIEL
EEKKHATIADYLDMIAKKSGRLISAALEAGGVAGNATDEQLNNLVTFGEKIGRAFQIQDDFLDIMADDGKSGKIAGGDVI
NGKKTYLLLRSIELTSGDDHRLLQSIIENNGISAERVPEIRSIYQRCGVLDETRLLIRRDTENALSAVDKLPHAEGREYL
KGFANILVKRDF
>Mature_332_residues
MNMSITQELVEKKYRLYHNLINEALASCFSAEAPVTLYAPAKYILDGKGKRIRPFLTLLASEAVCGSSEHALKVALAVEI
LHNFTLMHDDIMDQAELRHGRPTVHKQWNANVAILSGDMMIAYAYELALQSPSSRQIELVHILNDANITICEGQALDIEL
EEKKHATIADYLDMIAKKSGRLISAALEAGGVAGNATDEQLNNLVTFGEKIGRAFQIQDDFLDIMADDGKSGKIAGGDVI
NGKKTYLLLRSIELTSGDDHRLLQSIIENNGISAERVPEIRSIYQRCGVLDETRLLIRRDTENALSAVDKLPHAEGREYL
KGFANILVKRDF

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=314, Percent_Identity=26.4331210191083, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI209571582, Length=239, Percent_Identity=28.0334728033473, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4503685, Length=239, Percent_Identity=28.0334728033473, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI209571584, Length=239, Percent_Identity=28.0334728033473, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1789578, Length=289, Percent_Identity=30.4498269896194, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1786623, Length=217, Percent_Identity=37.7880184331797, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17505681, Length=325, Percent_Identity=24, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325188, Length=233, Percent_Identity=27.0386266094421, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24651612, Length=299, Percent_Identity=27.7591973244147, Blast_Score=117, Evalue=9e-27,
Organism=Drosophila melanogaster, GI17137582, Length=275, Percent_Identity=24.7272727272727, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 36776; Mature: 36776

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMSITQELVEKKYRLYHNLINEALASCFSAEAPVTLYAPAKYILDGKGKRIRPFLTLLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCHHHHHHHHH
SEAVCGSSEHALKVALAVEILHNFTLMHDDIMDQAELRHGRPTVHKQWNANVAILSGDMM
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEE
IAYAYELALQSPSSRQIELVHILNDANITICEGQALDIELEEKKHATIADYLDMIAKKSG
EEHHHHHHHCCCCCCCEEEEEEECCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHHCCC
RLISAALEAGGVAGNATDEQLNNLVTFGEKIGRAFQIQDDFLDIMADDGKSGKIAGGDVI
CEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCCCCCCEE
NGKKTYLLLRSIELTSGDDHRLLQSIIENNGISAERVPEIRSIYQRCGVLDETRLLIRRD
CCCEEEEEEEEEECCCCCHHHHHHHHHHCCCCCHHHCHHHHHHHHHCCCCCHHHHEEEEC
TENALSAVDKLPHAEGREYLKGFANILVKRDF
CHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNMSITQELVEKKYRLYHNLINEALASCFSAEAPVTLYAPAKYILDGKGKRIRPFLTLLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCHHHHHHHHH
SEAVCGSSEHALKVALAVEILHNFTLMHDDIMDQAELRHGRPTVHKQWNANVAILSGDMM
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEE
IAYAYELALQSPSSRQIELVHILNDANITICEGQALDIELEEKKHATIADYLDMIAKKSG
EEHHHHHHHCCCCCCCEEEEEEECCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHHCCC
RLISAALEAGGVAGNATDEQLNNLVTFGEKIGRAFQIQDDFLDIMADDGKSGKIAGGDVI
CEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCCCCCCEE
NGKKTYLLLRSIELTSGDDHRLLQSIIENNGISAERVPEIRSIYQRCGVLDETRLLIRRD
CCCEEEEEEEEEECCCCCHHHHHHHHHHCCCCCHHHCHHHHHHHHHCCCCCHHHHEEEEC
TENALSAVDKLPHAEGREYLKGFANILVKRDF
CHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7979381 [H]