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The map label for this gene is panD

Identifier: 119356218

GI number: 119356218

Start: 420548

End: 420943

Strand: Reverse

Name: panD

Synonym: Cpha266_0379

Alternate gene names: 119356218

Gene position: 420943-420548 (Counterclockwise)

Preceding gene: 119356219

Following gene: 119356217

Centisome position: 13.43

GC content: 43.94

Gene sequence:

>396_bases
ATGAAATTACACCTCTTAAAATCAAAAATCCACAACGCAAGGGTAACAAGCGGAGATCTTGAATATGAAGGAAGCATCAC
GATCGACCAGGAACTTCTCCTTCTGGCCGAGATGATTCCTAACGAAAAAGTTCTGGTTGTCAATAATAACAACGGCGAAC
GTTTTGAAACATATATTATCAATGGGGAACCCGGATCAAGAGTAATCCAGCTCAATGGAGCGGCAGCAAGATGCGCACTG
CCAGGCGATGAAATCATCATCATGACTTTTGCTGTCATGGATGAGAAAAAAGCCCGCACCTTTCAGCCTATGGTGCTTAT
CGTCGACCATCTCAACAACCCCAAACGCAGACATCGCATAGGACAGGAAGACGAACAACTTTCATCATCCATTTAA

Upstream 100 bases:

>100_bases
ACTGACAGGATATGGCTTTGAAAGTGACCAGGCGCTTAAAAAATACAGGATTTTCCGAGCAAGCGGTGAATCGCATTAAC
CTTCAACATTGTTTTTTTTA

Downstream 100 bases:

>100_bases
TCATCTGTTGTAACTGATGTCACTTGCTGTAATCATCATGGCTGCCGGAAAAGGCACCCGTATGCAATCCGAACTTCCGA
AAGTACTGCACAAAGCAAAT

Product: aspartate alpha-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MKLHLLKSKIHNARVTSGDLEYEGSITIDQELLLLAEMIPNEKVLVVNNNNGERFETYIINGEPGSRVIQLNGAAARCAL
PGDEIIIMTFAVMDEKKARTFQPMVLIVDHLNNPKRRHRIGQEDEQLSSSI

Sequences:

>Translated_131_residues
MKLHLLKSKIHNARVTSGDLEYEGSITIDQELLLLAEMIPNEKVLVVNNNNGERFETYIINGEPGSRVIQLNGAAARCAL
PGDEIIIMTFAVMDEKKARTFQPMVLIVDHLNNPKRRHRIGQEDEQLSSSI
>Mature_131_residues
MKLHLLKSKIHNARVTSGDLEYEGSITIDQELLLLAEMIPNEKVLVVNNNNGERFETYIINGEPGSRVIQLNGAAARCAL
PGDEIIIMTFAVMDEKKARTFQPMVLIVDHLNNPKRRHRIGQEDEQLSSSI

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=112, Percent_Identity=46.4285714285714, Blast_Score=108, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND_CHLPD (A1BDG1)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_910862.1
- ProteinModelPortal:   A1BDG1
- SMR:   A1BDG1
- STRING:   A1BDG1
- GeneID:   4568972
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0379
- NMPDR:   fig|290317.7.peg.387
- eggNOG:   COG0853
- HOGENOM:   HBG302821
- OMA:   LYSKIHR
- ProtClustDB:   PRK05449
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294
- TIGRFAMs:   TIGR00223

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 14736; Mature: 14736

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: ACT_SITE 25-25 ACT_SITE 58-58 BINDING 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHLLKSKIHNARVTSGDLEYEGSITIDQELLLLAEMIPNEKVLVVNNNNGERFETYII
CEEEEEHHHHCCCCCCCCCCEECCCEEEHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEE
NGEPGSRVIQLNGAAARCALPGDEIIIMTFAVMDEKKARTFQPMVLIVDHLNNPKRRHRI
ECCCCCEEEEECCCEEEEECCCCCEEEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHCC
GQEDEQLSSSI
CCCHHHHHCCC
>Mature Secondary Structure
MKLHLLKSKIHNARVTSGDLEYEGSITIDQELLLLAEMIPNEKVLVVNNNNGERFETYII
CEEEEEHHHHCCCCCCCCCCEECCCEEEHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEE
NGEPGSRVIQLNGAAARCALPGDEIIIMTFAVMDEKKARTFQPMVLIVDHLNNPKRRHRI
ECCCCCEEEEECCCEEEEECCCCCEEEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHCC
GQEDEQLSSSI
CCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA