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The map label for this gene is int [H]

Identifier: 119356102

GI number: 119356102

Start: 287225

End: 288241

Strand: Direct

Name: int [H]

Synonym: Cpha266_0257

Alternate gene names: 119356102

Gene position: 287225-288241 (Clockwise)

Preceding gene: 119356101

Following gene: 119356103

Centisome position: 9.17

GC content: 48.48

Gene sequence:

>1017_bases
ATGGTCGCTGATTCTCAAACAGTTTTACAGTCGACTGTGAATTCTCAGTCATTGCAACACGGCCCGAAATTATTGGAATT
ATTTCGGGAAGCTATGCGTGTTCGTCACTACAGCAGAAGGACAGAAGAGACATATTGTTCCTGGGTCAAGCGTTATGTTC
ATTTTCACAACATGAGGCATCCAAAAGAGATGAGAGAACCGGAGATCAATGCTTTTTTGACGCATCTTGCTGTGGAGGAA
AAGGTCAGTGCATCAACGCAGAATCAGGCATTGAGCGCACTTTTATTTCTTTACCGGCATGTGATAGGCAAAGAAATCGG
TGATCTTGGACACCTCATCCGTGCCAGAAAGCCAAGTCATTTACCCGTTGTGCTGACTCGGGACGAAGTGAAAGCTCTTC
TTGTTCAGCTTGCAGGTGTCAAGTGGTTAATGGCCTCGCTTATGTATGGCGCGGGGTTGAGGCTGATGGAATGTCTGCGA
TTGCGTGTGCAGGATATTGATTTCTCCAGCAATGAAATTCTGGTTCGCGATGGCAAGGGGGCAAAAGACCGGATCACGAT
GTTGCCGGAATCCCTGAAAAAGCCTCTCGCCGACCATCTGAAACAGATCAAAAGCCTTCATGATAAAGACCTTGCTGAAG
GTTGGGGACGTGTACTTCTGCCAGGAGCATTGGATCGCAAGTATCCCAACGCTCCTGCCGAATGGCGATGGCAGTGGGTT
TTTCCTCAGGAGCACCGATGGAAAAACGCGAAAACCGGCGAAGAAGGACGACACCACATGGATGAGTCACTGATTCAAAA
GGCTGTTAAAGCCGCGGTATTTCATGCACAATTGACAAAAAGGGCTACTTGCCATACATTCCGGCATTCTTTTGCAACTC
ACTTGCTGGAAGGCGGATATGACATCCGAACCGTTCAGGAACTACTTGGGCATAATGATGTGCGCACCACCATGATCTAT
ACGCATGTCTTGAACCGAGGGCCGTCTGGTGTCCGAAGCCCGGTAGACTGCTTGTAA

Upstream 100 bases:

>100_bases
GGTTGGTTAGTGCCGTATTATTTTGATGGCTCGACATTATTTTGCTATACTTTCAGTAAGCTGTTGTTGCGACAAGGCAA
ACATTAGAAAAAAAATGGAG

Downstream 100 bases:

>100_bases
GCAACGTTTTTATGCTGATCCGTATAAGACACAGAAATAAATCGTAATGCGAGGATTAACTTATTTAATTGCATGAGCTT
AATAGTTATTTTGCTGGTGT

Product: integron integrase

Products: NA

Alternate protein names: E2 protein [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MVADSQTVLQSTVNSQSLQHGPKLLELFREAMRVRHYSRRTEETYCSWVKRYVHFHNMRHPKEMREPEINAFLTHLAVEE
KVSASTQNQALSALLFLYRHVIGKEIGDLGHLIRARKPSHLPVVLTRDEVKALLVQLAGVKWLMASLMYGAGLRLMECLR
LRVQDIDFSSNEILVRDGKGAKDRITMLPESLKKPLADHLKQIKSLHDKDLAEGWGRVLLPGALDRKYPNAPAEWRWQWV
FPQEHRWKNAKTGEEGRHHMDESLIQKAVKAAVFHAQLTKRATCHTFRHSFATHLLEGGYDIRTVQELLGHNDVRTTMIY
THVLNRGPSGVRSPVDCL

Sequences:

>Translated_338_residues
MVADSQTVLQSTVNSQSLQHGPKLLELFREAMRVRHYSRRTEETYCSWVKRYVHFHNMRHPKEMREPEINAFLTHLAVEE
KVSASTQNQALSALLFLYRHVIGKEIGDLGHLIRARKPSHLPVVLTRDEVKALLVQLAGVKWLMASLMYGAGLRLMECLR
LRVQDIDFSSNEILVRDGKGAKDRITMLPESLKKPLADHLKQIKSLHDKDLAEGWGRVLLPGALDRKYPNAPAEWRWQWV
FPQEHRWKNAKTGEEGRHHMDESLIQKAVKAAVFHAQLTKRATCHTFRHSFATHLLEGGYDIRTVQELLGHNDVRTTMIY
THVLNRGPSGVRSPVDCL
>Mature_338_residues
MVADSQTVLQSTVNSQSLQHGPKLLELFREAMRVRHYSRRTEETYCSWVKRYVHFHNMRHPKEMREPEINAFLTHLAVEE
KVSASTQNQALSALLFLYRHVIGKEIGDLGHLIRARKPSHLPVVLTRDEVKALLVQLAGVKWLMASLMYGAGLRLMECLR
LRVQDIDFSSNEILVRDGKGAKDRITMLPESLKKPLADHLKQIKSLHDKDLAEGWGRVLLPGALDRKYPNAPAEWRWQWV
FPQEHRWKNAKTGEEGRHHMDESLIQKAVKAAVFHAQLTKRATCHTFRHSFATHLLEGGYDIRTVQELLGHNDVRTTMIY
THVLNRGPSGVRSPVDCL

Specific function: Putative integrase believed to be involved in the insertion of antibiotic resistance genes into plasmids and transposons [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=257, Percent_Identity=29.9610894941634, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR011946
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 38844; Mature: 38844

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVADSQTVLQSTVNSQSLQHGPKLLELFREAMRVRHYSRRTEETYCSWVKRYVHFHNMRH
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PKEMREPEINAFLTHLAVEEKVSASTQNQALSALLFLYRHVIGKEIGDLGHLIRARKPSH
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LPVVLTRDEVKALLVQLAGVKWLMASLMYGAGLRLMECLRLRVQDIDFSSNEILVRDGKG
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCC
AKDRITMLPESLKKPLADHLKQIKSLHDKDLAEGWGRVLLPGALDRKYPNAPAEWRWQWV
CHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHCCCCCCCCCCCEEEEE
FPQEHRWKNAKTGEEGRHHMDESLIQKAVKAAVFHAQLTKRATCHTFRHSFATHLLEGGY
CCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DIRTVQELLGHNDVRTTMIYTHVLNRGPSGVRSPVDCL
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVADSQTVLQSTVNSQSLQHGPKLLELFREAMRVRHYSRRTEETYCSWVKRYVHFHNMRH
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PKEMREPEINAFLTHLAVEEKVSASTQNQALSALLFLYRHVIGKEIGDLGHLIRARKPSH
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LPVVLTRDEVKALLVQLAGVKWLMASLMYGAGLRLMECLRLRVQDIDFSSNEILVRDGKG
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCC
AKDRITMLPESLKKPLADHLKQIKSLHDKDLAEGWGRVLLPGALDRKYPNAPAEWRWQWV
CHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHCCCCCCCCCCCEEEEE
FPQEHRWKNAKTGEEGRHHMDESLIQKAVKAAVFHAQLTKRATCHTFRHSFATHLLEGGY
CCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DIRTVQELLGHNDVRTTMIYTHVLNRGPSGVRSPVDCL
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2821509; 2823258; 3054482; 8195081; 2188588 [H]