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The map label for this gene is serB [H]

Identifier: 119356097

GI number: 119356097

Start: 279920

End: 281137

Strand: Reverse

Name: serB [H]

Synonym: Cpha266_0250

Alternate gene names: 119356097

Gene position: 281137-279920 (Counterclockwise)

Preceding gene: 119356098

Following gene: 119356096

Centisome position: 8.97

GC content: 57.88

Gene sequence:

>1218_bases
ATGAGCGAGCTTCTCCTTATCAATCTTACCGGCCTGGACAAACCGGGTCTGACGTCGAAAATAACGGCGATTCTTGCTGA
TGCGAGGGTACCGGTGCTCGATATCGGGCAGGCGGTGATCCATAACCATCTCAGCCTCGGCATGCTGGTTGAGGTGCCCA
AGGAGTCGGCTTCGTCGCCCGTTCTCAAAGATCTGCTCTTCTGCGCCCATACGCTCGGCATACAGATTTCCTTTACGCCG
GTAGCCGACGAGGAGTACGACCGGTGGGTGGGCGAACAGGGCAAGCCCCGATACCTGCTCTCGCTGCTGTCGAGAAAAAT
TTCAGCGGAACAGCTTAAGCGGGTATCGTCGATCGTTGCCGAACATGATCTCAATATCGACACCATCAGCCGCCTTTCAG
GCCGAATCCCGCTCGATAACGGCGACAACCACACCCGCGCCTGCGTGGAGTTCTCGCTGAGGGGAACCCTCTCTGACGAA
AACCTTTTTCGCGAACAGCTTCTGGCCATTACCGACAGCCTCGGCATCGACATCGCCTTCCAGGAGGACAATATTTTCCG
GCGGAACCGGCGCATGGTGGTGTTCGATATGGATTCGACCCTCATCACCTCGGAAGTGATCGACGAACTTGCCCTTGAAG
CGGGGGTCGGCGAAGAGGTATCGGCAATTACCGAACAGGCCATGCGGGGGGAACTGGATTTCAACGAAAGCCTGCAGCGG
CGGGTGGCGCAGCTCAAGGGGCTTGACGAACATGTGATGGAGAGCATCGCCGCACGGTTGCAGCTCACCGAGGGTGCAGA
ACGGCTCTTCGGCAACCTGAAGCGACTCGGCTACAAAACCGCGATTCTTTCCGGAGGGTTCACCTATTTCGGCCACTATC
TGCAGAAAAAGCTCTCGATCGACTATGTCTACGCGAACACCCTTGAAATCGAGAACGGCTGCCTGACGGGAAGGGTGCTC
GGCAGGGTTGTGGACGGAGCGAGAAAGGCCGAACTGCTCGAACTGCTTGCCGAAAAGGAGAACATCAGCCTTGAACAGAC
CGTTGCAGTGGGTGACGGAGCAAACGACCTGCCGATGCTCGGCAAGGCGGGACTCGGCATCGCTTTCAGGGCAAAGCCCA
TCGTGCGCGAACGGGCGAAACAGGCGATCTCGACTCTCGGCCTCGACGCCATCCTCTACCTGATGGGGTTCAGGGATCGG
GATGAGCTGTCGGAATAG

Upstream 100 bases:

>100_bases
TGTCATGGGAGATGACCGCAATAAACGGTTCCATGAGAGTACTGCGAAATGCCTTGTCGATACCGCCTGTTGCGTAGAGC
TAACCGTTAACCTCACTGAT

Downstream 100 bases:

>100_bases
GATCGCCAGCAAATCATCGACCTGCTCCGCCAAGGCTTTTCCCGGCAGGAAGGCATTTCGGTTGCGTTAAGACTTAATGT
CGTTAGCATCAACACTACAC

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSELLLINLTGLDKPGLTSKITAILADARVPVLDIGQAVIHNHLSLGMLVEVPKESASSPVLKDLLFCAHTLGIQISFTP
VADEEYDRWVGEQGKPRYLLSLLSRKISAEQLKRVSSIVAEHDLNIDTISRLSGRIPLDNGDNHTRACVEFSLRGTLSDE
NLFREQLLAITDSLGIDIAFQEDNIFRRNRRMVVFDMDSTLITSEVIDELALEAGVGEEVSAITEQAMRGELDFNESLQR
RVAQLKGLDEHVMESIAARLQLTEGAERLFGNLKRLGYKTAILSGGFTYFGHYLQKKLSIDYVYANTLEIENGCLTGRVL
GRVVDGARKAELLELLAEKENISLEQTVAVGDGANDLPMLGKAGLGIAFRAKPIVRERAKQAISTLGLDAILYLMGFRDR
DELSE

Sequences:

>Translated_405_residues
MSELLLINLTGLDKPGLTSKITAILADARVPVLDIGQAVIHNHLSLGMLVEVPKESASSPVLKDLLFCAHTLGIQISFTP
VADEEYDRWVGEQGKPRYLLSLLSRKISAEQLKRVSSIVAEHDLNIDTISRLSGRIPLDNGDNHTRACVEFSLRGTLSDE
NLFREQLLAITDSLGIDIAFQEDNIFRRNRRMVVFDMDSTLITSEVIDELALEAGVGEEVSAITEQAMRGELDFNESLQR
RVAQLKGLDEHVMESIAARLQLTEGAERLFGNLKRLGYKTAILSGGFTYFGHYLQKKLSIDYVYANTLEIENGCLTGRVL
GRVVDGARKAELLELLAEKENISLEQTVAVGDGANDLPMLGKAGLGIAFRAKPIVRERAKQAISTLGLDAILYLMGFRDR
DELSE
>Mature_404_residues
SELLLINLTGLDKPGLTSKITAILADARVPVLDIGQAVIHNHLSLGMLVEVPKESASSPVLKDLLFCAHTLGIQISFTPV
ADEEYDRWVGEQGKPRYLLSLLSRKISAEQLKRVSSIVAEHDLNIDTISRLSGRIPLDNGDNHTRACVEFSLRGTLSDEN
LFREQLLAITDSLGIDIAFQEDNIFRRNRRMVVFDMDSTLITSEVIDELALEAGVGEEVSAITEQAMRGELDFNESLQRR
VAQLKGLDEHVMESIAARLQLTEGAERLFGNLKRLGYKTAILSGGFTYFGHYLQKKLSIDYVYANTLEIENGCLTGRVLG
RVVDGARKAELLELLAEKENISLEQTVAVGDGANDLPMLGKAGLGIAFRAKPIVRERAKQAISTLGLDAILYLMGFRDRD
ELSE

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=200, Percent_Identity=33, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1790849, Length=196, Percent_Identity=52.5510204081633, Blast_Score=195, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI115534454, Length=231, Percent_Identity=29.8701298701299, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=301, Percent_Identity=37.8737541528239, Blast_Score=187, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24661601, Length=212, Percent_Identity=30.6603773584906, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 44694; Mature: 44563

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELLLINLTGLDKPGLTSKITAILADARVPVLDIGQAVIHNHLSLGMLVEVPKESASSP
CCCEEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCH
VLKDLLFCAHTLGIQISFTPVADEEYDRWVGEQGKPRYLLSLLSRKISAEQLKRVSSIVA
HHHHHHHHHHHHCEEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
EHDLNIDTISRLSGRIPLDNGDNHTRACVEFSLRGTLSDENLFREQLLAITDSLGIDIAF
HCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEE
QEDNIFRRNRRMVVFDMDSTLITSEVIDELALEAGVGEEVSAITEQAMRGELDFNESLQR
CCCCHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHH
RVAQLKGLDEHVMESIAARLQLTEGAERLFGNLKRLGYKTAILSGGFTYFGHYLQKKLSI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCE
DYVYANTLEIENGCLTGRVLGRVVDGARKAELLELLAEKENISLEQTVAVGDGANDLPML
EEEEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHEEEECCCCCCCCCC
GKAGLGIAFRAKPIVRERAKQAISTLGLDAILYLMGFRDRDELSE
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure 
SELLLINLTGLDKPGLTSKITAILADARVPVLDIGQAVIHNHLSLGMLVEVPKESASSP
CCEEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCH
VLKDLLFCAHTLGIQISFTPVADEEYDRWVGEQGKPRYLLSLLSRKISAEQLKRVSSIVA
HHHHHHHHHHHHCEEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
EHDLNIDTISRLSGRIPLDNGDNHTRACVEFSLRGTLSDENLFREQLLAITDSLGIDIAF
HCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEE
QEDNIFRRNRRMVVFDMDSTLITSEVIDELALEAGVGEEVSAITEQAMRGELDFNESLQR
CCCCHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHH
RVAQLKGLDEHVMESIAARLQLTEGAERLFGNLKRLGYKTAILSGGFTYFGHYLQKKLSI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCE
DYVYANTLEIENGCLTGRVLGRVVDGARKAELLELLAEKENISLEQTVAVGDGANDLPML
EEEEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHEEEECCCCCCCCCC
GKAGLGIAFRAKPIVRERAKQAISTLGLDAILYLMGFRDRDELSE
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA