Click here to switch to the map view.

The map label for this gene is ygbD [C]

Identifier: 119356091

GI number: 119356091

Start: 275723

End: 277081

Strand: Direct

Name: ygbD [C]

Synonym: Cpha266_0244

Alternate gene names: 119356091

Gene position: 275723-277081 (Clockwise)

Preceding gene: 119356090

Following gene: 119356092

Centisome position: 8.8

GC content: 52.54

Gene sequence:

>1359_bases
ATGAAGAAAAATGTGGATGTCCTTGTTATAGGTGGAAGCGCGGCCGGTATCGTTGCCGCTTCAACCGGAAAGGCGTTTTA
CCCGTTGAAAAATTTTCTTATTGTCCGTCGGGAGCGCGAAGCCGTAGTCCCCTGCGGAATACCATACATTTATGGTACCC
TGGAAAGTATCAACCAGAACATCATTCCGAATGCGCATATCGAACAGGCCGGCGTCGAACTGTTTATCGATGAAGTCGTT
GCCGTCGACCGCGGTGCAAAAGTAGCCACTACCGCTGACGGTACGCAAATAACCTTCGATAAACTTGTTTTTGCAACCGG
CTCCATGCCGAAAGTCCCCGCCTGGCTGAAAGGCACCGGTCTTGGCAATGTGTTTACCATTCCCAAGGATCGGGACTATC
TCGAGAATCTCCGTATGACGCTTGAGCAGTGCACGAACATCGTTATCATCGGAGGCGGATTTATCGGTGTTGAAATTGCC
GACGAACTTCGCAAAAAAGGAAAGCGGATCACCTTGATTGAAGTCATGCCGCACGTTTTAAGCGCGGCATTTGATGACGA
CCTCTCCGTTAAGGTTGAAAAGATCCTTACCGATAACGGCGTTATGCTCAGAACCGGCGAAAAGGTCAGAGAGCTCAGCG
GCGAGGGATCGGTTTCGGGAGTGGTTCTTGAAAACGGAGAGATTCTTGCGGCTGATGCGGTCATTCTTGCAACCGGATAC
GCCCCTAATGTGGATCTTGCCCGTAATGCAGGCATAAAAATCAATGAACTCGGAGCTATCAGGGTAGACGAGTACATGCG
AACCGAAGACAAGGATATTTTTGCCGTCGGCGATTGCGCCGAAAAGTTTTCGTTCATCACCCGTATCGTCAAAGGATTGA
TGCTTGCCGCCACGGCTTGTTCCGAAGCCAGAATTGCCGGTATGAACCTGTACGGGCTGTCGCGACTGAGAACCTTCAGC
GGCACCATTTCAATATTTTCGACGGCAATCGGAGGGACAACCTTCGCCGCGGCTGGCGTTACCGAGCATCTCGCTCTCGA
TCGCGGATTTGACGTCATATCAGCATCGGCTGAAGGCATTGACAAACACCCGAAATCTCTGCCCGGAACCAGCAGCCAGT
TTGTCAAGCTCATTGTCAACCGCGATTCCGGTCTTGTGCTTGGCGGAGCGGTTGTCGGAGGGGTCAGCGCGGGAGAGCTG
ATCAATGTTATCGGGGTGATCATCGAAAACAAGATGACCATCCACGAGGTGCTCACCCTTCAGGTCGGGACCCATCCGCT
GCTGACCGGTCCCCCGACAGGGTATCCCCTCATCAAGGCTGCCGAGGCGGTGGTCAAAAAACTTCGAAGCTCGCGATAA

Upstream 100 bases:

>100_bases
GAAAAGATCCCGAAGGCATACAGAAGGCGTTTGATTCCTTTGCAGCGTCAGTCAGAGAAAAGGTCAGCGCCAAATAAATA
ATTTTAATACAGAACGCCTT

Downstream 100 bases:

>100_bases
GATGAAAAAAATACCCGGAAGTGAAAAGAGCGATGCCGCTTGAGCCTGTCGCCGTTTTGGCGAAGGCTCTCTGTGCCGGG
ATAAAGGAACGACTATTGAT

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKKNVDVLVIGGSAAGIVAASTGKAFYPLKNFLIVRREREAVVPCGIPYIYGTLESINQNIIPNAHIEQAGVELFIDEVV
AVDRGAKVATTADGTQITFDKLVFATGSMPKVPAWLKGTGLGNVFTIPKDRDYLENLRMTLEQCTNIVIIGGGFIGVEIA
DELRKKGKRITLIEVMPHVLSAAFDDDLSVKVEKILTDNGVMLRTGEKVRELSGEGSVSGVVLENGEILAADAVILATGY
APNVDLARNAGIKINELGAIRVDEYMRTEDKDIFAVGDCAEKFSFITRIVKGLMLAATACSEARIAGMNLYGLSRLRTFS
GTISIFSTAIGGTTFAAAGVTEHLALDRGFDVISASAEGIDKHPKSLPGTSSQFVKLIVNRDSGLVLGGAVVGGVSAGEL
INVIGVIIENKMTIHEVLTLQVGTHPLLTGPPTGYPLIKAAEAVVKKLRSSR

Sequences:

>Translated_452_residues
MKKNVDVLVIGGSAAGIVAASTGKAFYPLKNFLIVRREREAVVPCGIPYIYGTLESINQNIIPNAHIEQAGVELFIDEVV
AVDRGAKVATTADGTQITFDKLVFATGSMPKVPAWLKGTGLGNVFTIPKDRDYLENLRMTLEQCTNIVIIGGGFIGVEIA
DELRKKGKRITLIEVMPHVLSAAFDDDLSVKVEKILTDNGVMLRTGEKVRELSGEGSVSGVVLENGEILAADAVILATGY
APNVDLARNAGIKINELGAIRVDEYMRTEDKDIFAVGDCAEKFSFITRIVKGLMLAATACSEARIAGMNLYGLSRLRTFS
GTISIFSTAIGGTTFAAAGVTEHLALDRGFDVISASAEGIDKHPKSLPGTSSQFVKLIVNRDSGLVLGGAVVGGVSAGEL
INVIGVIIENKMTIHEVLTLQVGTHPLLTGPPTGYPLIKAAEAVVKKLRSSR
>Mature_452_residues
MKKNVDVLVIGGSAAGIVAASTGKAFYPLKNFLIVRREREAVVPCGIPYIYGTLESINQNIIPNAHIEQAGVELFIDEVV
AVDRGAKVATTADGTQITFDKLVFATGSMPKVPAWLKGTGLGNVFTIPKDRDYLENLRMTLEQCTNIVIIGGGFIGVEIA
DELRKKGKRITLIEVMPHVLSAAFDDDLSVKVEKILTDNGVMLRTGEKVRELSGEGSVSGVVLENGEILAADAVILATGY
APNVDLARNAGIKINELGAIRVDEYMRTEDKDIFAVGDCAEKFSFITRIVKGLMLAATACSEARIAGMNLYGLSRLRTFS
GTISIFSTAIGGTTFAAAGVTEHLALDRGFDVISASAEGIDKHPKSLPGTSSQFVKLIVNRDSGLVLGGAVVGGVSAGEL
INVIGVIIENKMTIHEVLTLQVGTHPLLTGPPTGYPLIKAAEAVVKKLRSSR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=354, Percent_Identity=27.683615819209, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI21389617, Length=354, Percent_Identity=27.683615819209, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI226437568, Length=354, Percent_Identity=27.683615819209, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI22202629, Length=258, Percent_Identity=25.968992248062, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4757732, Length=274, Percent_Identity=25.5474452554745, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI50301238, Length=281, Percent_Identity=29.8932384341637, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789065, Length=234, Percent_Identity=32.0512820512821, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1786307, Length=341, Percent_Identity=28.7390029325513, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789765, Length=360, Percent_Identity=23.6111111111111, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082354, Length=261, Percent_Identity=27.9693486590038, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87081717, Length=277, Percent_Identity=25.2707581227437, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788892, Length=237, Percent_Identity=27.4261603375527, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789915, Length=194, Percent_Identity=29.3814432989691, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17559934, Length=218, Percent_Identity=29.8165137614679, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24585130, Length=264, Percent_Identity=25.7575757575758, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24639257, Length=203, Percent_Identity=29.064039408867, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281359715, Length=206, Percent_Identity=29.126213592233, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281359713, Length=206, Percent_Identity=29.126213592233, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24639250, Length=206, Percent_Identity=29.126213592233, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI18543267, Length=206, Percent_Identity=29.126213592233, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24639252, Length=206, Percent_Identity=29.126213592233, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21358499, Length=270, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 47935; Mature: 47935

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNVDVLVIGGSAAGIVAASTGKAFYPLKNFLIVRREREAVVPCGIPYIYGTLESINQN
CCCCCEEEEECCCCCCEEEECCCCEECCCHHEEEEEECCCEECCCCCHHHHHHHHHHCCC
IIPNAHIEQAGVELFIDEVVAVDRGAKVATTADGTQITFDKLVFATGSMPKVPAWLKGTG
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEHEEEECCCCCCCCCEEECCC
LGNVFTIPKDRDYLENLRMTLEQCTNIVIIGGGFIGVEIADELRKKGKRITLIEVMPHVL
CCCEEECCCCHHHHHHHHHHHHHCCCEEEECCCEEEEHHHHHHHHCCCEEEEHHHHHHHH
SAAFDDDLSVKVEKILTDNGVMLRTGEKVRELSGEGSVSGVVLENGEILAADAVILATGY
HHHCCCCCCEEEEEEECCCCEEEECCHHHHHCCCCCCEEEEEEECCCEEEECEEEEEECC
APNVDLARNAGIKINELGAIRVDEYMRTEDKDIFAVGDCAEKFSFITRIVKGLMLAATAC
CCCCCHHCCCCEEEECCCCEEEHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHC
SEARIAGMNLYGLSRLRTFSGTISIFSTAIGGTTFAAAGVTEHLALDRGFDVISASAEGI
CCCCEECCEEHHHHHHHHHCCHHHHHHHHCCCCHHHHCCCHHHHHHHCCCCEEECCCCCC
DKHPKSLPGTSSQFVKLIVNRDSGLVLGGAVVGGVSAGELINVIGVIIENKMTIHEVLTL
CCCCCCCCCCHHHEEEEEEECCCCEEEECCEECCCCHHHHHHHHHHHHCCCEEEEHEEEE
QVGTHPLLTGPPTGYPLIKAAEAVVKKLRSSR
EECCCCEECCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKNVDVLVIGGSAAGIVAASTGKAFYPLKNFLIVRREREAVVPCGIPYIYGTLESINQN
CCCCCEEEEECCCCCCEEEECCCCEECCCHHEEEEEECCCEECCCCCHHHHHHHHHHCCC
IIPNAHIEQAGVELFIDEVVAVDRGAKVATTADGTQITFDKLVFATGSMPKVPAWLKGTG
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEHEEEECCCCCCCCCEEECCC
LGNVFTIPKDRDYLENLRMTLEQCTNIVIIGGGFIGVEIADELRKKGKRITLIEVMPHVL
CCCEEECCCCHHHHHHHHHHHHHCCCEEEECCCEEEEHHHHHHHHCCCEEEEHHHHHHHH
SAAFDDDLSVKVEKILTDNGVMLRTGEKVRELSGEGSVSGVVLENGEILAADAVILATGY
HHHCCCCCCEEEEEEECCCCEEEECCHHHHHCCCCCCEEEEEEECCCEEEECEEEEEECC
APNVDLARNAGIKINELGAIRVDEYMRTEDKDIFAVGDCAEKFSFITRIVKGLMLAATAC
CCCCCHHCCCCEEEECCCCEEEHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHC
SEARIAGMNLYGLSRLRTFSGTISIFSTAIGGTTFAAAGVTEHLALDRGFDVISASAEGI
CCCCEECCEEHHHHHHHHHCCHHHHHHHHCCCCHHHHCCCHHHHHHHCCCCEEECCCCCC
DKHPKSLPGTSSQFVKLIVNRDSGLVLGGAVVGGVSAGELINVIGVIIENKMTIHEVLTL
CCCCCCCCCCHHHEEEEEEECCCCEEEECCEECCCCHHHHHHHHHHHHCCCEEEEHEEEE
QVGTHPLLTGPPTGYPLIKAAEAVVKKLRSSR
EECCCCEECCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA