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The map label for this gene is hupB2 [H]

Identifier: 119356085

GI number: 119356085

Start: 267907

End: 268182

Strand: Direct

Name: hupB2 [H]

Synonym: Cpha266_0238

Alternate gene names: 119356085

Gene position: 267907-268182 (Clockwise)

Preceding gene: 119356081

Following gene: 119356086

Centisome position: 8.55

GC content: 47.83

Gene sequence:

>276_bases
ATGTCAAAAGCTGAGTTAGTAGAGAAAATAGCCTCACAGGCCGGTTTGACCAAAGTCGATGCTGAGCGTGCCGTCAATGC
CTTTATGAATGTCGTTACAGAATCCTTGAAAGAAGGGGAGGATGTGACTCTGGTAGGTTTCGGGACATTTACTACCGGAG
AAAGAGCCGAAAGGCAGGGGCGTAACCCGCAGAATGGCGAAACCATAACCATTGCCGCAAAAAAGGTTGTTAAATTTAAA
CCCGGAAAAGCGCTGAAAGCCGGTGTAGAGGGTTGA

Upstream 100 bases:

>100_bases
TAAAAAGCAATTGGATGTTAGTCGGGCGCTTTTTAAATTCACTTCATAAGTAGCTCTAAAATAAATAATTCATGTTCCTT
CAACCATAATCAGATGCCAT

Downstream 100 bases:

>100_bases
TTTTCAAGACGTTACGTATATGGTTTTTATAAAGTCCATCATAGGCAAAGCCATGATGGGCTTTTTTTATCATTCATCCT
CTTTAATTTATGGCCAACAG

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 91; Mature: 90

Protein sequence:

>91_residues
MSKAELVEKIASQAGLTKVDAERAVNAFMNVVTESLKEGEDVTLVGFGTFTTGERAERQGRNPQNGETITIAAKKVVKFK
PGKALKAGVEG

Sequences:

>Translated_91_residues
MSKAELVEKIASQAGLTKVDAERAVNAFMNVVTESLKEGEDVTLVGFGTFTTGERAERQGRNPQNGETITIAAKKVVKFK
PGKALKAGVEG
>Mature_90_residues
SKAELVEKIASQAGLTKVDAERAVNAFMNVVTESLKEGEDVTLVGFGTFTTGERAERQGRNPQNGETITIAAKKVVKFKP
GKALKAGVEG

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=59.5505617977528, Blast_Score=104, Evalue=1e-24,
Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=52.2222222222222, Blast_Score=89, Evalue=5e-20,
Organism=Escherichia coli, GI1788005, Length=90, Percent_Identity=43.3333333333333, Blast_Score=82, Evalue=7e-18,
Organism=Escherichia coli, GI1787141, Length=87, Percent_Identity=37.9310344827586, Blast_Score=69, Evalue=5e-14,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9651; Mature: 9520

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAELVEKIASQAGLTKVDAERAVNAFMNVVTESLKEGEDVTLVGFGTFTTGERAERQG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCC
RNPQNGETITIAAKKVVKFKPGKALKAGVEG
CCCCCCCEEEEEEEEHHEECCCCCCCCCCCC
>Mature Secondary Structure 
SKAELVEKIASQAGLTKVDAERAVNAFMNVVTESLKEGEDVTLVGFGTFTTGERAERQG
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCC
RNPQNGETITIAAKKVVKFKPGKALKAGVEG
CCCCCCCEEEEEEEEHHEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10722605; 10761919 [H]