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The map label for this gene is rpoB

Identifier: 119356080

GI number: 119356080

Start: 256527

End: 260465

Strand: Direct

Name: rpoB

Synonym: Cpha266_0233

Alternate gene names: 119356080

Gene position: 256527-260465 (Clockwise)

Preceding gene: 119356079

Following gene: 119356081

Centisome position: 8.19

GC content: 45.77

Gene sequence:

>3939_bases
ATGCAATTTGATAAAAGCGAGGTGCATGTGAAAGTGGCTGATGCAACACCAACACCGTGTATTGACTTTTCAAAAATTCA
GAGTGTTATAGATCCTCCCGACCTATTAAAAGTTCAGTTAGATTCATTTCATAATTTTATACAGGATAGTGTTCCGCTTG
CCAAAAGAAGAGATCAGGGTCTGGAGAGAGTGCTTCGCAGTGCATTTCCCATTACTGATACTCGCGGACTATACCTGCTT
GAGTATATATCCTACAGTTTCGATAAACCGAAATATACGGTTGAGGATTGTATTGAGCGAGGCCTTACCTATGATGTTTC
GCTGAAAGTCAAGCTTAAGCTTTCCTATAAGGATGAGCCTGACGAAGCGGACTGGAAAGAGACAATTCAGCAGGAGGTCT
ATCTCGGCAGAATTCCCTATATGACTGAACGCGGTACGTTTATTGTCAATGGGGCCGAGCGCGTCGTTGTTGCCCAGTTG
CATCGTTCCCCCGGGGTTGTATTCAGCGAAGCTATACATCCTAACGGCAAAAAGATGTATTCGGCCAAGATCGTGCCGAC
AAGGGGTTCATGGATCGAGTTTCAGACTGATATTAATAATCAGATATTCGTCTATATCGACCAGAAGAAAAACTTTCTGG
TTACTGCACTTTTGCGCGCTATCGGGTTTGCAAAAGATGAAGATATTCTCGGCTTGTTCGATCTTGTTGAAGAGGTGAAA
ATAACCTCGGCGAAAAAAGAGCAGCTTATAGGGCAGTATCTTGCTTCCGATATTGTTGACATGCAGACTGGCGAGGTTGT
CAGTGCAAGAACCGCGATTACCGAAGATATTGTCGATCAGATCATTGCTGCAGGATACAAGAGCGTCCGGGTGATGAAAA
GCTTTTCCGGGAACGATAAGGGGCCGGACAAATCAATTATTATCAATACTATTCTCAACGATAACTCTGCAACCGAAGAA
GAGGCGCTTGAAATAGTATATGAAGAGCTCCGTGCCAACGAGGCTCCTGATATCGACGCGGCAAGAAGTTTTCTTGAACG
AACATTTTTTAATCAGAAGAAGTACGATCTTGGCGATGTAGGACGATACCGGATCCGTAAAAAACTAAGCAAGGAGTTTG
AAGAGCTGCACGGTTATCTTGACGGGCAGCCCGAGCTTAAAAAACTTTCCGATACTATTTATGAAAAGATTCTCCATACG
ATTCAATCTTTTTCAGATGAGCCGATTGGAGGAGATATTCTGGTGCTTACCCACTATGATATCATTGCTGTTATTTATTA
CCTCATAAAACTTGTAAACGGTCAGGCTGAGGTTGACGATGTCGACCATCTTGCAAATCGCCGAGTTCGCTCGGTTGGTG
AGCAGCTTGCCGCACAGTTTGTAATAGGTCTGGCAAGAATGGGTAAAAATGTCAGGGAAAAGCTCAATTCAAGAGACTCT
GATAAAATAGCACCTTCGGATCTTATCAATGCAAGGACTGTATCAAGCGTCGTATCGAGCTTTTTTGCTACAAGTCAGCT
ATCGCAGTTCATGGATCAGACCAATCCTCTTGCTGAAATGACGAACAAGCGGAGGGTTTCTGCTCTTGGACCTGGAGGGT
TGACTCGTGAACGCGCAGGTTTTGAAGTACGCGACGTTCATTATACGCACTATGGACGCCTTTGTCCTATCGAGACACCG
GAAGGTCCCAATATCGGGCTTATTTCTTCCCTCTCGGTCTATGCGGAAATAAACGACAAAGGATTTATTCAGACGCCATA
CAGGGTGGTGACAAATGGAGTCGTAACCGACACCGTGCTCATGCTGTCGGCTGAAGATGAAGAAAACAAGATAACGGTTC
CGGTCAGTATTCCGCTTGATGAGAATATGAAGATTGCGATCGAGTCTGTTCAGGCACGAACGAAAGGCGATTACCCGCTT
GTTCCGGCTGAAGACGTCAATTATATGGATGTTTCGCCAGTACAGATTGTCAGTGCTGCAGCAGCCCTGATTCCGTTTCT
TGAGCATGATGACGGAAACCGTGCACTTATGGGCGCAAACATGCAGCGCCAGGCAGTTCCGCTGCTTACAGCCGAGGCTC
CTATAGTCGGAACCGGTATGGAGTCAAAAGTCGCAAGAGATTCACGTTCAGTTATTCTTGCCGAAGGCGATGGCATTGTC
GATGATGTTACTGCTGAATATATCAAGGTTCGCTACGATATTGATGCAGATACCGATGTTCGTTTATCGCTGCTTGATCC
TGACGAAGGTTTGAAAACCTACAAGCTGATCAAGTTCAAACGTTCTAACCAGGACACCTGTATTTCCCAGAAACCACTGA
TCCATATCGGTCAGCGAGTATCGAAAGGAGATGTTCTTGCAGACAGCTCCTCGACGGAAAACGGAGAGCTTGCTCTGGGC
AAAAACGTTCTTGTTGCATTCATGCCATGGCGTGGCTATAACTTTGAAGACGCTATTATTCTCAGCGAGCGTCTTGTCTA
CGACGATGTTTTCACATCGATTCATATTCACGAATTTGAAGCGAATGTTCGGGATACAAAGCGCGGCGAAGAGCAGTTTA
CGCGCGACATTTACAATGTCAGCGAAGATGCGCTTAGAAATCTCGATGAAAACGGCATTGTTCGTATCGGAGCCGAGGTC
AAGGAGAGGGATATACTTGTCGGGAAAATTACTCCGAAAGGCGAAAGCGATCCGACGCCGGAAGAAAAATTGCTCCGTGC
GATTTTCGGTGATAAATCAAGCGACGTGAAAGACGCCTCAATGCATGTTCCCGCAGGAATGAAGGGGATAGTCATTAAAA
CGAAGCTATTCAGCCGCAAGAAAAAGGTCGGGCTTGATATCAAGGAAAAAATAGAGATACTTGAAAAAAAGTACGACTAC
AAAGAGTACGACTTGCGGAAGAAATTTTTAAAGAGACTGAAACAACTGCTTGAGGGAAAAACTTCAACCGGTATATACAG
TGACAAGGGAAAACTGCTTGTAGCTGAGGACGCGGTGTATGATGACAGCGTTCTTGAAAGATTCACGGCTATCCCTTTTC
TCGAGTCGATTGATTTTGTCAAGGGAGTTACTCAGTCCGAGAAAGTGAATGAAAATGTGATGTTGCTTGTCAAGGAGTTC
CGTCTCAAACTCAAGGATCTGAACGACGAGAGGGACAATGAAAAGTACAAGCTTAACGTTGGAGACGAACTTCCTCCCGG
AATCGAGGAGCTTGCAAAAGTCTACATTGCCCAGAAGAGAAAAATCCAGGTGGGTGATAAAATGGCCGGGCGGCATGGTA
ACAAGGGTGTTGTAGGCAAAATACTTCCTATCGAGGATATGCCGTTTATGGAAAACGGTAAACCTGTTGATATTGTACTT
AATCCCCTTGGCGTACCGAGCCGAATGAATATCGGTCAGCTTTACGAAACATCGCTTGGCTGGGCCGGAAAAGAACTTGG
TGTCAAATTCAAGACTCCGATTTTTAATGGCGCAACGTACCAGGAAGTACAGCAGGAGCTTGAAAAGGCAGGGCTTCCTT
CCCATGGCAAGGTAAGCTTGTATGACGGAAGAACCGGCGAGCAGTTTGATGACGAGGTCACGATAGGGTATATCTATATG
CTGAAATTAAGTCATCTGGTTGATGACAAGATTCATGCCCGTTCGACTGGCCCATACTCGCTTATAACCCAGCAGCCACT
TGGCGGTAAAGCTCAGTTTGGAGGACAGCGGTTTGGTGAAATGGAGGTATGGGCGCTTGAAGCTTACGGCGCGGCCAATA
TCCTCAGGGAGATGTTGACAGTCAAATCCGATGATGTTATAGGTCGAAATAAAACCTATGAGGCTATCGTGAAGGGTCAG
AATCTACCGGAACCGGGAACGCCGGAGTCATTTAATGTGCTTGTCAGGGAACTGCAGGGTCTCGGTCTTGAAATTCGTAT
TGACGACAGGGTTCCTTAG

Upstream 100 bases:

>100_bases
ATGCCCGTTTCCCGGTAGTAGTGATAGCGGCTCAGCCGAACATGGATTGTTCGGCTGAGTTTTTGCGGTTCTTTGTAATG
ACTTAATTTGTTAGATATTC

Downstream 100 bases:

>100_bases
TAATCTGGTTATCAGAGGGTGCATCATTAACGGGATTTAATTAAGGTCGTTTTAAAAAGGACATTGACTATGATTTTTTC
ACAGGGAGCATCGCCGTTAA

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1312; Mature: 1312

Protein sequence:

>1312_residues
MQFDKSEVHVKVADATPTPCIDFSKIQSVIDPPDLLKVQLDSFHNFIQDSVPLAKRRDQGLERVLRSAFPITDTRGLYLL
EYISYSFDKPKYTVEDCIERGLTYDVSLKVKLKLSYKDEPDEADWKETIQQEVYLGRIPYMTERGTFIVNGAERVVVAQL
HRSPGVVFSEAIHPNGKKMYSAKIVPTRGSWIEFQTDINNQIFVYIDQKKNFLVTALLRAIGFAKDEDILGLFDLVEEVK
ITSAKKEQLIGQYLASDIVDMQTGEVVSARTAITEDIVDQIIAAGYKSVRVMKSFSGNDKGPDKSIIINTILNDNSATEE
EALEIVYEELRANEAPDIDAARSFLERTFFNQKKYDLGDVGRYRIRKKLSKEFEELHGYLDGQPELKKLSDTIYEKILHT
IQSFSDEPIGGDILVLTHYDIIAVIYYLIKLVNGQAEVDDVDHLANRRVRSVGEQLAAQFVIGLARMGKNVREKLNSRDS
DKIAPSDLINARTVSSVVSSFFATSQLSQFMDQTNPLAEMTNKRRVSALGPGGLTRERAGFEVRDVHYTHYGRLCPIETP
EGPNIGLISSLSVYAEINDKGFIQTPYRVVTNGVVTDTVLMLSAEDEENKITVPVSIPLDENMKIAIESVQARTKGDYPL
VPAEDVNYMDVSPVQIVSAAAALIPFLEHDDGNRALMGANMQRQAVPLLTAEAPIVGTGMESKVARDSRSVILAEGDGIV
DDVTAEYIKVRYDIDADTDVRLSLLDPDEGLKTYKLIKFKRSNQDTCISQKPLIHIGQRVSKGDVLADSSSTENGELALG
KNVLVAFMPWRGYNFEDAIILSERLVYDDVFTSIHIHEFEANVRDTKRGEEQFTRDIYNVSEDALRNLDENGIVRIGAEV
KERDILVGKITPKGESDPTPEEKLLRAIFGDKSSDVKDASMHVPAGMKGIVIKTKLFSRKKKVGLDIKEKIEILEKKYDY
KEYDLRKKFLKRLKQLLEGKTSTGIYSDKGKLLVAEDAVYDDSVLERFTAIPFLESIDFVKGVTQSEKVNENVMLLVKEF
RLKLKDLNDERDNEKYKLNVGDELPPGIEELAKVYIAQKRKIQVGDKMAGRHGNKGVVGKILPIEDMPFMENGKPVDIVL
NPLGVPSRMNIGQLYETSLGWAGKELGVKFKTPIFNGATYQEVQQELEKAGLPSHGKVSLYDGRTGEQFDDEVTIGYIYM
LKLSHLVDDKIHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAANILREMLTVKSDDVIGRNKTYEAIVKGQ
NLPEPGTPESFNVLVRELQGLGLEIRIDDRVP

Sequences:

>Translated_1312_residues
MQFDKSEVHVKVADATPTPCIDFSKIQSVIDPPDLLKVQLDSFHNFIQDSVPLAKRRDQGLERVLRSAFPITDTRGLYLL
EYISYSFDKPKYTVEDCIERGLTYDVSLKVKLKLSYKDEPDEADWKETIQQEVYLGRIPYMTERGTFIVNGAERVVVAQL
HRSPGVVFSEAIHPNGKKMYSAKIVPTRGSWIEFQTDINNQIFVYIDQKKNFLVTALLRAIGFAKDEDILGLFDLVEEVK
ITSAKKEQLIGQYLASDIVDMQTGEVVSARTAITEDIVDQIIAAGYKSVRVMKSFSGNDKGPDKSIIINTILNDNSATEE
EALEIVYEELRANEAPDIDAARSFLERTFFNQKKYDLGDVGRYRIRKKLSKEFEELHGYLDGQPELKKLSDTIYEKILHT
IQSFSDEPIGGDILVLTHYDIIAVIYYLIKLVNGQAEVDDVDHLANRRVRSVGEQLAAQFVIGLARMGKNVREKLNSRDS
DKIAPSDLINARTVSSVVSSFFATSQLSQFMDQTNPLAEMTNKRRVSALGPGGLTRERAGFEVRDVHYTHYGRLCPIETP
EGPNIGLISSLSVYAEINDKGFIQTPYRVVTNGVVTDTVLMLSAEDEENKITVPVSIPLDENMKIAIESVQARTKGDYPL
VPAEDVNYMDVSPVQIVSAAAALIPFLEHDDGNRALMGANMQRQAVPLLTAEAPIVGTGMESKVARDSRSVILAEGDGIV
DDVTAEYIKVRYDIDADTDVRLSLLDPDEGLKTYKLIKFKRSNQDTCISQKPLIHIGQRVSKGDVLADSSSTENGELALG
KNVLVAFMPWRGYNFEDAIILSERLVYDDVFTSIHIHEFEANVRDTKRGEEQFTRDIYNVSEDALRNLDENGIVRIGAEV
KERDILVGKITPKGESDPTPEEKLLRAIFGDKSSDVKDASMHVPAGMKGIVIKTKLFSRKKKVGLDIKEKIEILEKKYDY
KEYDLRKKFLKRLKQLLEGKTSTGIYSDKGKLLVAEDAVYDDSVLERFTAIPFLESIDFVKGVTQSEKVNENVMLLVKEF
RLKLKDLNDERDNEKYKLNVGDELPPGIEELAKVYIAQKRKIQVGDKMAGRHGNKGVVGKILPIEDMPFMENGKPVDIVL
NPLGVPSRMNIGQLYETSLGWAGKELGVKFKTPIFNGATYQEVQQELEKAGLPSHGKVSLYDGRTGEQFDDEVTIGYIYM
LKLSHLVDDKIHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAANILREMLTVKSDDVIGRNKTYEAIVKGQ
NLPEPGTPESFNVLVRELQGLGLEIRIDDRVP
>Mature_1312_residues
MQFDKSEVHVKVADATPTPCIDFSKIQSVIDPPDLLKVQLDSFHNFIQDSVPLAKRRDQGLERVLRSAFPITDTRGLYLL
EYISYSFDKPKYTVEDCIERGLTYDVSLKVKLKLSYKDEPDEADWKETIQQEVYLGRIPYMTERGTFIVNGAERVVVAQL
HRSPGVVFSEAIHPNGKKMYSAKIVPTRGSWIEFQTDINNQIFVYIDQKKNFLVTALLRAIGFAKDEDILGLFDLVEEVK
ITSAKKEQLIGQYLASDIVDMQTGEVVSARTAITEDIVDQIIAAGYKSVRVMKSFSGNDKGPDKSIIINTILNDNSATEE
EALEIVYEELRANEAPDIDAARSFLERTFFNQKKYDLGDVGRYRIRKKLSKEFEELHGYLDGQPELKKLSDTIYEKILHT
IQSFSDEPIGGDILVLTHYDIIAVIYYLIKLVNGQAEVDDVDHLANRRVRSVGEQLAAQFVIGLARMGKNVREKLNSRDS
DKIAPSDLINARTVSSVVSSFFATSQLSQFMDQTNPLAEMTNKRRVSALGPGGLTRERAGFEVRDVHYTHYGRLCPIETP
EGPNIGLISSLSVYAEINDKGFIQTPYRVVTNGVVTDTVLMLSAEDEENKITVPVSIPLDENMKIAIESVQARTKGDYPL
VPAEDVNYMDVSPVQIVSAAAALIPFLEHDDGNRALMGANMQRQAVPLLTAEAPIVGTGMESKVARDSRSVILAEGDGIV
DDVTAEYIKVRYDIDADTDVRLSLLDPDEGLKTYKLIKFKRSNQDTCISQKPLIHIGQRVSKGDVLADSSSTENGELALG
KNVLVAFMPWRGYNFEDAIILSERLVYDDVFTSIHIHEFEANVRDTKRGEEQFTRDIYNVSEDALRNLDENGIVRIGAEV
KERDILVGKITPKGESDPTPEEKLLRAIFGDKSSDVKDASMHVPAGMKGIVIKTKLFSRKKKVGLDIKEKIEILEKKYDY
KEYDLRKKFLKRLKQLLEGKTSTGIYSDKGKLLVAEDAVYDDSVLERFTAIPFLESIDFVKGVTQSEKVNENVMLLVKEF
RLKLKDLNDERDNEKYKLNVGDELPPGIEELAKVYIAQKRKIQVGDKMAGRHGNKGVVGKILPIEDMPFMENGKPVDIVL
NPLGVPSRMNIGQLYETSLGWAGKELGVKFKTPIFNGATYQEVQQELEKAGLPSHGKVSLYDGRTGEQFDDEVTIGYIYM
LKLSHLVDDKIHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAANILREMLTVKSDDVIGRNKTYEAIVKGQ
NLPEPGTPESFNVLVRELQGLGLEIRIDDRVP

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908505, Length=203, Percent_Identity=41.871921182266, Blast_Score=157, Evalue=8e-38,
Organism=Homo sapiens, GI238908503, Length=203, Percent_Identity=41.871921182266, Blast_Score=157, Evalue=8e-38,
Organism=Homo sapiens, GI4505941, Length=196, Percent_Identity=40.3061224489796, Blast_Score=146, Evalue=1e-34,
Organism=Homo sapiens, GI33469941, Length=259, Percent_Identity=33.2046332046332, Blast_Score=140, Evalue=1e-32,
Organism=Homo sapiens, GI212286172, Length=259, Percent_Identity=33.2046332046332, Blast_Score=139, Evalue=1e-32,
Organism=Escherichia coli, GI1790419, Length=1404, Percent_Identity=46.011396011396, Blast_Score=1132, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=249, Percent_Identity=38.1526104417671, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17552304, Length=196, Percent_Identity=39.2857142857143, Blast_Score=143, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17506623, Length=185, Percent_Identity=38.9189189189189, Blast_Score=135, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324781, Length=249, Percent_Identity=36.144578313253, Blast_Score=157, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6324725, Length=195, Percent_Identity=38.4615384615385, Blast_Score=145, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6325267, Length=213, Percent_Identity=41.3145539906103, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI17647877, Length=194, Percent_Identity=41.2371134020619, Blast_Score=152, Evalue=2e-36,
Organism=Drosophila melanogaster, GI17136444, Length=255, Percent_Identity=34.5098039215686, Blast_Score=147, Evalue=7e-35,
Organism=Drosophila melanogaster, GI17136446, Length=205, Percent_Identity=35.1219512195122, Blast_Score=120, Evalue=6e-27,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_CHLPD (A1BD23)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_910724.1
- ProteinModelPortal:   A1BD23
- STRING:   A1BD23
- GeneID:   4570800
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0233
- NMPDR:   fig|290317.7.peg.245
- eggNOG:   COG0085
- HOGENOM:   HBG285547
- OMA:   IGRNKTY
- ProtClustDB:   PRK00405
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 147003; Mature: 147003

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFDKSEVHVKVADATPTPCIDFSKIQSVIDPPDLLKVQLDSFHNFIQDSVPLAKRRDQG
CCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LERVLRSAFPITDTRGLYLLEYISYSFDKPKYTVEDCIERGLTYDVSLKVKLKLSYKDEP
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCCEEEEEEEEEEEEECCCCC
DEADWKETIQQEVYLGRIPYMTERGTFIVNGAERVVVAQLHRSPGVVFSEAIHPNGKKMY
CCCHHHHHHHHHHHHCCCCCEECCCEEEECCCCEEEEEEHHCCCCCEEECCCCCCCCEEE
SAKIVPTRGSWIEFQTDINNQIFVYIDQKKNFLVTALLRAIGFAKDEDILGLFDLVEEVK
EEEEEECCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ITSAKKEQLIGQYLASDIVDMQTGEVVSARTAITEDIVDQIIAAGYKSVRVMKSFSGNDK
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
GPDKSIIINTILNDNSATEEEALEIVYEELRANEAPDIDAARSFLERTFFNQKKYDLGDV
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCH
GRYRIRKKLSKEFEELHGYLDGQPELKKLSDTIYEKILHTIQSFSDEPIGGDILVLTHYD
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECHH
IIAVIYYLIKLVNGQAEVDDVDHLANRRVRSVGEQLAAQFVIGLARMGKNVREKLNSRDS
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
DKIAPSDLINARTVSSVVSSFFATSQLSQFMDQTNPLAEMTNKRRVSALGPGGLTRERAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEECCCCCCCHHHCC
FEVRDVHYTHYGRLCPIETPEGPNIGLISSLSVYAEINDKGFIQTPYRVVTNGVVTDTVL
CEEEEEEEECCCCCCCCCCCCCCCCCEEECEEEEEEECCCCCEECCHHHHHCCHHEEEEE
MLSAEDEENKITVPVSIPLDENMKIAIESVQARTKGDYPLVPAEDVNYMDVSPVQIVSAA
EEECCCCCCEEEEEEECCCCCCCEEEEEHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
AALIPFLEHDDGNRALMGANMQRQAVPLLTAEAPIVGTGMESKVARDSRSVILAEGDGIV
HHHHHHHCCCCCCEEEECCCCCHHCCCEEECCCCEEECCCHHHHHCCCCCEEEECCCCCH
DDVTAEYIKVRYDIDADTDVRLSLLDPDEGLKTYKLIKFKRSNQDTCISQKPLIHIGQRV
HHHCCEEEEEEEECCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHCCC
SKGDVLADSSSTENGELALGKNVLVAFMPWRGYNFEDAIILSERLVYDDVFTSIHIHEFE
CCCCEEECCCCCCCCCEEECCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHEEEEEEEC
ANVRDTKRGEEQFTRDIYNVSEDALRNLDENGIVRIGAEVKERDILVGKITPKGESDPTP
CCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCH
EEKLLRAIFGDKSSDVKDASMHVPAGMKGIVIKTKLFSRKKKVGLDIKEKIEILEKKYDY
HHHHHHHHHCCCCCCCCCCCEECCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHCCC
KEYDLRKKFLKRLKQLLEGKTSTGIYSDKGKLLVAEDAVYDDSVLERFTAIPFLESIDFV
HHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEECCCCCCHHHHHHHHHCHHHHHHHHH
KGVTQSEKVNENVMLLVKEFRLKLKDLNDERDNEKYKLNVGDELPPGIEELAKVYIAQKR
HCCCCHHHCCCHHEEHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCC
KIQVGDKMAGRHGNKGVVGKILPIEDMPFMENGKPVDIVLNPLGVPSRMNIGQLYETSLG
EEECCCHHCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHCC
WAGKELGVKFKTPIFNGATYQEVQQELEKAGLPSHGKVSLYDGRTGEQFDDEVTIGYIYM
CCCHHCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEEEHHHHH
LKLSHLVDDKIHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAANILREMLT
HHHHHHHCCHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHH
VKSDDVIGRNKTYEAIVKGQNLPEPGTPESFNVLVRELQGLGLEIRIDDRVP
CCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCC
>Mature Secondary Structure
MQFDKSEVHVKVADATPTPCIDFSKIQSVIDPPDLLKVQLDSFHNFIQDSVPLAKRRDQG
CCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LERVLRSAFPITDTRGLYLLEYISYSFDKPKYTVEDCIERGLTYDVSLKVKLKLSYKDEP
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCCEEEEEEEEEEEEECCCCC
DEADWKETIQQEVYLGRIPYMTERGTFIVNGAERVVVAQLHRSPGVVFSEAIHPNGKKMY
CCCHHHHHHHHHHHHCCCCCEECCCEEEECCCCEEEEEEHHCCCCCEEECCCCCCCCEEE
SAKIVPTRGSWIEFQTDINNQIFVYIDQKKNFLVTALLRAIGFAKDEDILGLFDLVEEVK
EEEEEECCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ITSAKKEQLIGQYLASDIVDMQTGEVVSARTAITEDIVDQIIAAGYKSVRVMKSFSGNDK
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
GPDKSIIINTILNDNSATEEEALEIVYEELRANEAPDIDAARSFLERTFFNQKKYDLGDV
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCH
GRYRIRKKLSKEFEELHGYLDGQPELKKLSDTIYEKILHTIQSFSDEPIGGDILVLTHYD
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECHH
IIAVIYYLIKLVNGQAEVDDVDHLANRRVRSVGEQLAAQFVIGLARMGKNVREKLNSRDS
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
DKIAPSDLINARTVSSVVSSFFATSQLSQFMDQTNPLAEMTNKRRVSALGPGGLTRERAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEECCCCCCCHHHCC
FEVRDVHYTHYGRLCPIETPEGPNIGLISSLSVYAEINDKGFIQTPYRVVTNGVVTDTVL
CEEEEEEEECCCCCCCCCCCCCCCCCEEECEEEEEEECCCCCEECCHHHHHCCHHEEEEE
MLSAEDEENKITVPVSIPLDENMKIAIESVQARTKGDYPLVPAEDVNYMDVSPVQIVSAA
EEECCCCCCEEEEEEECCCCCCCEEEEEHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
AALIPFLEHDDGNRALMGANMQRQAVPLLTAEAPIVGTGMESKVARDSRSVILAEGDGIV
HHHHHHHCCCCCCEEEECCCCCHHCCCEEECCCCEEECCCHHHHHCCCCCEEEECCCCCH
DDVTAEYIKVRYDIDADTDVRLSLLDPDEGLKTYKLIKFKRSNQDTCISQKPLIHIGQRV
HHHCCEEEEEEEECCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHCCC
SKGDVLADSSSTENGELALGKNVLVAFMPWRGYNFEDAIILSERLVYDDVFTSIHIHEFE
CCCCEEECCCCCCCCCEEECCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHEEEEEEEC
ANVRDTKRGEEQFTRDIYNVSEDALRNLDENGIVRIGAEVKERDILVGKITPKGESDPTP
CCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCH
EEKLLRAIFGDKSSDVKDASMHVPAGMKGIVIKTKLFSRKKKVGLDIKEKIEILEKKYDY
HHHHHHHHHCCCCCCCCCCCEECCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHCCC
KEYDLRKKFLKRLKQLLEGKTSTGIYSDKGKLLVAEDAVYDDSVLERFTAIPFLESIDFV
HHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEECCCCCCHHHHHHHHHCHHHHHHHHH
KGVTQSEKVNENVMLLVKEFRLKLKDLNDERDNEKYKLNVGDELPPGIEELAKVYIAQKR
HCCCCHHHCCCHHEEHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCC
KIQVGDKMAGRHGNKGVVGKILPIEDMPFMENGKPVDIVLNPLGVPSRMNIGQLYETSLG
EEECCCHHCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHCC
WAGKELGVKFKTPIFNGATYQEVQQELEKAGLPSHGKVSLYDGRTGEQFDDEVTIGYIYM
CCCHHCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEEEHHHHH
LKLSHLVDDKIHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAANILREMLT
HHHHHHHCCHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHH
VKSDDVIGRNKTYEAIVKGQNLPEPGTPESFNVLVRELQGLGLEIRIDDRVP
CCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA