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The map label for this gene is hgiDIIM [H]

Identifier: 119355930

GI number: 119355930

Start: 94386

End: 95501

Strand: Reverse

Name: hgiDIIM [H]

Synonym: Cpha266_0080

Alternate gene names: 119355930

Gene position: 95501-94386 (Counterclockwise)

Preceding gene: 119355931

Following gene: 119355929

Centisome position: 3.05

GC content: 43.91

Gene sequence:

>1116_bases
ATGAATCAACAATCGGAGCCTACTTGCTCAAAAATTCGTGTTTATGACTTTTTCTCAGGTTGTGGGGGAACAAGTGTCGG
TTTTGGGCGAGCAGGTATACAGCACGCATTGGCTGTTGATTCTTGTTCTGACGCCATAAGTACCTATCAAAAAAATTTTA
TTGGTGTTCCCGTCATAACTGATCCAATAGAAACACTTAATGTTGACCGAATACAAAATTATTTCAGTCATAACCCGGAA
GTGAAGTTATTCTGTGGCTGTGCACCATGTCAGCCGTTTACCAAGCAGAAAACAAATACAAAAAAAGATGCGGCTTCGGA
TGATAGACGCGGATTACTTATATATTTCTCAGATATTGTTCATGCGTGTTTGCCTGAGCTTGTTTTTGTTGAGAACGTGC
CTGGTTTGCAAAAATTTTCTCTTGAAGATGGCGGGCCCTTGGCTATGTTTATAAGCCGATTAAAGCAAAACGACTACTTT
GTCGATTTTGATGTGATAGCAGCTCAGGACTATGGTTCACCTCAGGTTCGTAGACGGTTCGTGTTAATCGCAAGTAGGTT
GGGAAAGATTACTTTACCTGCACCAACGCATGGCCCAAATACAAAGAATTCGTATGTAACTGTTCATGATGCCATTGGCA
ACTTACCGTCCGTCAAACATGGCACAGAACATCCAGACAATCAAAATTACCCTAATCACCGGGCCGCAATGCTGTCAGCA
TTAAATCTTGAGCGCATTAGACACACTGGCGCGAACGGACGGCGAGATTGGCCTGAAAGACTATTGCCAAAATGTTATGC
ACAAAAGAAAGACGGAAAACGCTATGAAGGGCATTCGGACTGTTATACTCGATTAGCATGGGGCGAACCCGCACCAGGGT
TGACAACTCGTTGCATCAGTTATTCAAACGGTCGATTCGGACACCCAGAACAGGATCGTGCCATTACGATCAGGGAGGCA
GCAAAGCTGCAAGGATTTCCTGATGATTTCATTTTTACTGGTTCACTTAACTCTATGGCTCGCCAGATTGGCAATGCAGT
TCCTGTGTCTGTCGCGGAGGTATTCGGGAGACATTTTCTGAATCACGTTAAAGCCATGGAGAGTACAAATGGCTAA

Upstream 100 bases:

>100_bases
TTTTAGGTTCTGCATCAACTTGAAGTGTCGGTAACAATTACTATGAACTGTACAAATTAGTATAGATTGTGCAATTAGTC
AGAATGTCCTCCCATTACCT

Downstream 100 bases:

>100_bases
ATTTCGAACGAAAGCAAGGGCTGTTGATATGCTCGGCAGACAGCAGATAGCAGATGCATCAACCGCTATCAGTGAGCTTT
TCAAGAATGCTCATGACGCT

Product: DNA-cytosine methyltransferase

Products: NA

Alternate protein names: M.HgiDII; Cytosine-specific methyltransferase HgiDII [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MNQQSEPTCSKIRVYDFFSGCGGTSVGFGRAGIQHALAVDSCSDAISTYQKNFIGVPVITDPIETLNVDRIQNYFSHNPE
VKLFCGCAPCQPFTKQKTNTKKDAASDDRRGLLIYFSDIVHACLPELVFVENVPGLQKFSLEDGGPLAMFISRLKQNDYF
VDFDVIAAQDYGSPQVRRRFVLIASRLGKITLPAPTHGPNTKNSYVTVHDAIGNLPSVKHGTEHPDNQNYPNHRAAMLSA
LNLERIRHTGANGRRDWPERLLPKCYAQKKDGKRYEGHSDCYTRLAWGEPAPGLTTRCISYSNGRFGHPEQDRAITIREA
AKLQGFPDDFIFTGSLNSMARQIGNAVPVSVAEVFGRHFLNHVKAMESTNG

Sequences:

>Translated_371_residues
MNQQSEPTCSKIRVYDFFSGCGGTSVGFGRAGIQHALAVDSCSDAISTYQKNFIGVPVITDPIETLNVDRIQNYFSHNPE
VKLFCGCAPCQPFTKQKTNTKKDAASDDRRGLLIYFSDIVHACLPELVFVENVPGLQKFSLEDGGPLAMFISRLKQNDYF
VDFDVIAAQDYGSPQVRRRFVLIASRLGKITLPAPTHGPNTKNSYVTVHDAIGNLPSVKHGTEHPDNQNYPNHRAAMLSA
LNLERIRHTGANGRRDWPERLLPKCYAQKKDGKRYEGHSDCYTRLAWGEPAPGLTTRCISYSNGRFGHPEQDRAITIREA
AKLQGFPDDFIFTGSLNSMARQIGNAVPVSVAEVFGRHFLNHVKAMESTNG
>Mature_371_residues
MNQQSEPTCSKIRVYDFFSGCGGTSVGFGRAGIQHALAVDSCSDAISTYQKNFIGVPVITDPIETLNVDRIQNYFSHNPE
VKLFCGCAPCQPFTKQKTNTKKDAASDDRRGLLIYFSDIVHACLPELVFVENVPGLQKFSLEDGGPLAMFISRLKQNDYF
VDFDVIAAQDYGSPQVRRRFVLIASRLGKITLPAPTHGPNTKNSYVTVHDAIGNLPSVKHGTEHPDNQNYPNHRAAMLSA
LNLERIRHTGANGRRDWPERLLPKCYAQKKDGKRYEGHSDCYTRLAWGEPAPGLTTRCISYSNGRFGHPEQDRAITIREA
AKLQGFPDDFIFTGSLNSMARQIGNAVPVSVAEVFGRHFLNHVKAMESTNG

Specific function: This methylase recognizes the double-stranded sequence GTCGAC, causes specific methylation on C-? on both strands and protects the DNA from cleavage by the HgiDII endonuclease [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4503351, Length=458, Percent_Identity=25.9825327510917, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI195927037, Length=458, Percent_Identity=25.9825327510917, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 41153; Mature: 41153

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQSEPTCSKIRVYDFFSGCGGTSVGFGRAGIQHALAVDSCSDAISTYQKNFIGVPVIT
CCCCCCCCHHHEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEC
DPIETLNVDRIQNYFSHNPEVKLFCGCAPCQPFTKQKTNTKKDAASDDRRGLLIYFSDIV
CCHHHCCHHHHHHHHCCCCCEEEEECCCCCCCCHHCCCCCCCCCCCCCCCEEEEEHHHHH
HACLPELVFVENVPGLQKFSLEDGGPLAMFISRLKQNDYFVDFDVIAAQDYGSPQVRRRF
HHHHHHHEECCCCCCCEEECCCCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHHHH
VLIASRLGKITLPAPTHGPNTKNSYVTVHDAIGNLPSVKHGTEHPDNQNYPNHRAAMLSA
HHHHHHCCCEECCCCCCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LNLERIRHTGANGRRDWPERLLPKCYAQKKDGKRYEGHSDCYTRLAWGEPAPGLTTRCIS
HHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHEECCCCCCCCCHHHEEE
YSNGRFGHPEQDRAITIREAAKLQGFPDDFIFTGSLNSMARQIGNAVPVSVAEVFGRHFL
CCCCCCCCCCCCCEEEEHHHHHHCCCCCCEEEECCHHHHHHHHCCCCCHHHHHHHHHHHH
NHVKAMESTNG
HHHHHHHCCCC
>Mature Secondary Structure
MNQQSEPTCSKIRVYDFFSGCGGTSVGFGRAGIQHALAVDSCSDAISTYQKNFIGVPVIT
CCCCCCCCHHHEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEC
DPIETLNVDRIQNYFSHNPEVKLFCGCAPCQPFTKQKTNTKKDAASDDRRGLLIYFSDIV
CCHHHCCHHHHHHHHCCCCCEEEEECCCCCCCCHHCCCCCCCCCCCCCCCEEEEEHHHHH
HACLPELVFVENVPGLQKFSLEDGGPLAMFISRLKQNDYFVDFDVIAAQDYGSPQVRRRF
HHHHHHHEECCCCCCCEEECCCCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHHHH
VLIASRLGKITLPAPTHGPNTKNSYVTVHDAIGNLPSVKHGTEHPDNQNYPNHRAAMLSA
HHHHHHCCCEECCCCCCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LNLERIRHTGANGRRDWPERLLPKCYAQKKDGKRYEGHSDCYTRLAWGEPAPGLTTRCIS
HHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHEECCCCCCCCCHHHEEE
YSNGRFGHPEQDRAITIREAAKLQGFPDDFIFTGSLNSMARQIGNAVPVSVAEVFGRHFL
CCCCCCCCCCCCCEEEEHHHHHHCCCCCCEEEECCHHHHHHHHCCCCCHHHHHHHHHHHH
NHVKAMESTNG
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1937045; 7607523 [H]