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The map label for this gene is yabD [H]

Identifier: 118582005

GI number: 118582005

Start: 3987746

End: 3988555

Strand: Reverse

Name: yabD [H]

Synonym: Ppro_3606

Alternate gene names: 118582005

Gene position: 3988555-3987746 (Counterclockwise)

Preceding gene: 118582006

Following gene: 118582004

Centisome position: 99.51

GC content: 66.17

Gene sequence:

>810_bases
ATGAATCCACAGGAGTCGGAAGCGCAAATCGAGGACGGCATCAGGCTGCTGGATACCCATTGCCACCTGAATTGCGAGCC
GCTTCTCTCCAACTTGCCGGGAGTCCTGGAGGCGGCACACCGCGCCGGGGTGGTCGGTTGCGTCGTGCCCGGGGTTCATC
CCGCTGACTGGGAGCTGATGGCCGGGCTGACGCGTGAGCACGCCGGACTGTTTCCCGCCTTTGGCATTCATCCCCTGCAT
GCGGACCTGGCCGATGGGGCTGCCCTGGAACGGCTCGCACAAATTGCCGCCAGCGGGGTTGCCCTGGGCGAGATCGGCCT
TGACCCCACCTACCCTGGTGCGCTGGATCGGCAGGAACAGGCCTTCCGGGAACAGCTGCGCCTGGCAATCAGGCTGGGGC
TGCCGGTACTGGTCCACTGCAGGCGTCTCTTCCAGCGCACCCTGACGGTTCTCAGAGAGGAAAAGGCCGGCCGGGTGGGC
GGCATCATGCACGCCTTTTCCGGATCGCCGGAGATGGCCCGGGAGTTCATCAGGCTGGGGTTTGCCATCTCCCTCTGCGG
AACGGTGACCTGGCGGGGGGCGGCCCGTCCGGTGCGCCTGGCTGGCCAGATTCCCCTGGAAAGCCTGGTGCTGGAGACCG
ATGCGCCTGACATGGCGCCCGAGCCCTTCCGGGGGGAGTCAAACCGGCCTTCGTGCCTGCGGGAGGTGCTGGTTGCGGTG
GCGGGTATCCGTGATATGCTGGTGCATGATCTGGCCCGGGCCACAACGGTCAACACGCTGCGGGTTCTTGGTCGCATAAC
CCTGCCATGA

Upstream 100 bases:

>100_bases
GACCCGTATGCTGGAAAAGCTGGTCAACCTGTTCGGCTGGTTTCTGTAAAACCATGACTGGTGATCCGTAATTTGTCGCC
AATCACAAAGGTTCATGCCC

Downstream 100 bases:

>100_bases
ACACTGTCTTTTTCGCCAGAGCTGTGCTACGGTACCACACGCCGTCATTTCAGGATGGAGAGCGTCATGAAACCTGTTCT
TTTGTTGAGTACCGTCCTTG

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MNPQESEAQIEDGIRLLDTHCHLNCEPLLSNLPGVLEAAHRAGVVGCVVPGVHPADWELMAGLTREHAGLFPAFGIHPLH
ADLADGAALERLAQIAASGVALGEIGLDPTYPGALDRQEQAFREQLRLAIRLGLPVLVHCRRLFQRTLTVLREEKAGRVG
GIMHAFSGSPEMAREFIRLGFAISLCGTVTWRGAARPVRLAGQIPLESLVLETDAPDMAPEPFRGESNRPSCLREVLVAV
AGIRDMLVHDLARATTVNTLRVLGRITLP

Sequences:

>Translated_269_residues
MNPQESEAQIEDGIRLLDTHCHLNCEPLLSNLPGVLEAAHRAGVVGCVVPGVHPADWELMAGLTREHAGLFPAFGIHPLH
ADLADGAALERLAQIAASGVALGEIGLDPTYPGALDRQEQAFREQLRLAIRLGLPVLVHCRRLFQRTLTVLREEKAGRVG
GIMHAFSGSPEMAREFIRLGFAISLCGTVTWRGAARPVRLAGQIPLESLVLETDAPDMAPEPFRGESNRPSCLREVLVAV
AGIRDMLVHDLARATTVNTLRVLGRITLP
>Mature_269_residues
MNPQESEAQIEDGIRLLDTHCHLNCEPLLSNLPGVLEAAHRAGVVGCVVPGVHPADWELMAGLTREHAGLFPAFGIHPLH
ADLADGAALERLAQIAASGVALGEIGLDPTYPGALDRQEQAFREQLRLAIRLGLPVLVHCRRLFQRTLTVLREEKAGRVG
GIMHAFSGSPEMAREFIRLGFAISLCGTVTWRGAARPVRLAGQIPLESLVLETDAPDMAPEPFRGESNRPSCLREVLVAV
AGIRDMLVHDLARATTVNTLRVLGRITLP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=271, Percent_Identity=32.8413284132841, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI110349734, Length=271, Percent_Identity=32.8413284132841, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI226061853, Length=276, Percent_Identity=32.2463768115942, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI226061614, Length=261, Percent_Identity=32.5670498084291, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=33.4782608695652, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI225903424, Length=232, Percent_Identity=26.2931034482759, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI14042943, Length=266, Percent_Identity=25.5639097744361, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1787342, Length=254, Percent_Identity=36.2204724409449, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87082439, Length=259, Percent_Identity=33.976833976834, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=29.4573643410853, Blast_Score=98, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71980746, Length=261, Percent_Identity=27.2030651340996, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17559024, Length=217, Percent_Identity=32.258064516129, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24648690, Length=287, Percent_Identity=27.1777003484321, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29072; Mature: 29072

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPQESEAQIEDGIRLLDTHCHLNCEPLLSNLPGVLEAAHRAGVVGCVVPGVHPADWELM
CCCCHHHHHHHHCHHHHHHHCCCCCHHHHHCCCHHHHHHHHCCEEEEECCCCCCCCHHHH
AGLTREHAGLFPAFGIHPLHADLADGAALERLAQIAASGVALGEIGLDPTYPGALDRQEQ
HHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHH
AFREQLRLAIRLGLPVLVHCRRLFQRTLTVLREEKAGRVGGIMHAFSGSPEMAREFIRLG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHH
FAISLCGTVTWRGAARPVRLAGQIPLESLVLETDAPDMAPEPFRGESNRPSCLREVLVAV
HHHHHHHHHEECCCCCCEEEECCCCHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
AGIRDMLVHDLARATTVNTLRVLGRITLP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNPQESEAQIEDGIRLLDTHCHLNCEPLLSNLPGVLEAAHRAGVVGCVVPGVHPADWELM
CCCCHHHHHHHHCHHHHHHHCCCCCHHHHHCCCHHHHHHHHCCEEEEECCCCCCCCHHHH
AGLTREHAGLFPAFGIHPLHADLADGAALERLAQIAASGVALGEIGLDPTYPGALDRQEQ
HHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHH
AFREQLRLAIRLGLPVLVHCRRLFQRTLTVLREEKAGRVGGIMHAFSGSPEMAREFIRLG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHH
FAISLCGTVTWRGAARPVRLAGQIPLESLVLETDAPDMAPEPFRGESNRPSCLREVLVAV
HHHHHHHHHEECCCCCCEEEECCCCHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
AGIRDMLVHDLARATTVNTLRVLGRITLP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]