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The map label for this gene is htpX [H]

Identifier: 118581968

GI number: 118581968

Start: 3945293

End: 3946150

Strand: Reverse

Name: htpX [H]

Synonym: Ppro_3569

Alternate gene names: 118581968

Gene position: 3946150-3945293 (Counterclockwise)

Preceding gene: 118581969

Following gene: 118581967

Centisome position: 98.46

GC content: 61.19

Gene sequence:

>858_bases
ATGAATCAACTCAAGACAACCCTTCTCCTCTCTCTCCTCACCGTGCTGATGGTCCTGATGGGAAGCGCCATCGGCGGCAA
GACCGGTATGGTTTTCGCCTTCTTCATGGCAGCTGCCATGAACTTCTTCTCCTACTGGTTTTCCGACAAGATAGTCCTGA
AGATGTACGGCGCTCAGGAGATCAGCGAGCACGATAACCCCGCCTTCTACGGCATGGTGCGGAGGCTGGCGCTCCAGGCC
GGTCTCCCCATGCCAAAGGTCTACATCATTCCATCCGAAAGCCCCAACGCCTTCGCAACTGGCCGGAATCCGGAGCATGC
CGCCGTTGCCGCCACCGCGGGGATTTTACGCATTCTCTCGTCCGAGGAACTGGCAGGAGTCATGGCCCATGAACTGGCCC
ATGTCCGGAACCGTGACATTCTGGTCGGCACCATCGCCGCCACGTTTGCCGGCGCGATTTCCATGATCGGCAACATGCTC
CAGTGGGGCGCCCTGCTCGGGGCGGGGAGAGGCGATGACGAGGAGGGTTCCGGAGGCCTGATCGGTTCACTTGTCATGGC
CATCGTCGCCCCGATTGCGGCCATGCTGATCCAGATGGCCGTCTCCCGCTCCCGGGAGTATCTTGCCGACGAGACCGGCG
CCAGGATATGCGGCAATCCTCTGGCTCTGGCCGGCGCACTGCGAAAGCTCCATACCGCATCCCACATGATCCCGATGCAG
GAGGCCCGACCCGCGACCGCCCACATGTTCATCGTGAATCCCCTGAGCGGTCGCTCTCTGGCGAACCTGTTTTCCACGCA
TCCTCCCATGGAGGAACGCATTGCCCGGCTGGAAAGCATGGGAACGAGAGGGCGGTAA

Upstream 100 bases:

>100_bases
CATTCATGTGCCAACAAGACCTTTATCCAGGCTCACATGCCGGGGGTAAAGGTCTTTTTTATTACCCCCGGCGATACCCC
AATCGTCGGAGGTAATCACG

Downstream 100 bases:

>100_bases
GCGGTTTTTCCGCAAGGCCGAAAACGCCACCGGCACGGTCAGCCGCCCTGCCGTCGCCCTGATGCCGCGGCAGCACACAC
CACGATTGCTGCCTTCGACA

Product: peptidase M48, Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MNQLKTTLLLSLLTVLMVLMGSAIGGKTGMVFAFFMAAAMNFFSYWFSDKIVLKMYGAQEISEHDNPAFYGMVRRLALQA
GLPMPKVYIIPSESPNAFATGRNPEHAAVAATAGILRILSSEELAGVMAHELAHVRNRDILVGTIAATFAGAISMIGNML
QWGALLGAGRGDDEEGSGGLIGSLVMAIVAPIAAMLIQMAVSRSREYLADETGARICGNPLALAGALRKLHTASHMIPMQ
EARPATAHMFIVNPLSGRSLANLFSTHPPMEERIARLESMGTRGR

Sequences:

>Translated_285_residues
MNQLKTTLLLSLLTVLMVLMGSAIGGKTGMVFAFFMAAAMNFFSYWFSDKIVLKMYGAQEISEHDNPAFYGMVRRLALQA
GLPMPKVYIIPSESPNAFATGRNPEHAAVAATAGILRILSSEELAGVMAHELAHVRNRDILVGTIAATFAGAISMIGNML
QWGALLGAGRGDDEEGSGGLIGSLVMAIVAPIAAMLIQMAVSRSREYLADETGARICGNPLALAGALRKLHTASHMIPMQ
EARPATAHMFIVNPLSGRSLANLFSTHPPMEERIARLESMGTRGR
>Mature_285_residues
MNQLKTTLLLSLLTVLMVLMGSAIGGKTGMVFAFFMAAAMNFFSYWFSDKIVLKMYGAQEISEHDNPAFYGMVRRLALQA
GLPMPKVYIIPSESPNAFATGRNPEHAAVAATAGILRILSSEELAGVMAHELAHVRNRDILVGTIAATFAGAISMIGNML
QWGALLGAGRGDDEEGSGGLIGSLVMAIVAPIAAMLIQMAVSRSREYLADETGARICGNPLALAGALRKLHTASHMIPMQ
EARPATAHMFIVNPLSGRSLANLFSTHPPMEERIARLESMGTRGR

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=290, Percent_Identity=30.6896551724138, Blast_Score=107, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 30456; Mature: 30456

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLKTTLLLSLLTVLMVLMGSAIGGKTGMVFAFFMAAAMNFFSYWFSDKIVLKMYGAQE
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHH
ISEHDNPAFYGMVRRLALQAGLPMPKVYIIPSESPNAFATGRNPEHAAVAATAGILRILS
HHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHH
SEELAGVMAHELAHVRNRDILVGTIAATFAGAISMIGNMLQWGALLGAGRGDDEEGSGGL
HHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
IGSLVMAIVAPIAAMLIQMAVSRSREYLADETGARICGNPLALAGALRKLHTASHMIPMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHCCCHH
EARPATAHMFIVNPLSGRSLANLFSTHPPMEERIARLESMGTRGR
HCCCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNQLKTTLLLSLLTVLMVLMGSAIGGKTGMVFAFFMAAAMNFFSYWFSDKIVLKMYGAQE
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHH
ISEHDNPAFYGMVRRLALQAGLPMPKVYIIPSESPNAFATGRNPEHAAVAATAGILRILS
HHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHH
SEELAGVMAHELAHVRNRDILVGTIAATFAGAISMIGNMLQWGALLGAGRGDDEEGSGGL
HHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
IGSLVMAIVAPIAAMLIQMAVSRSREYLADETGARICGNPLALAGALRKLHTASHMIPMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHCCCHH
EARPATAHMFIVNPLSGRSLANLFSTHPPMEERIARLESMGTRGR
HCCCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA