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The map label for this gene is nuoE [H]

Identifier: 118581918

GI number: 118581918

Start: 3890183

End: 3890701

Strand: Reverse

Name: nuoE [H]

Synonym: Ppro_3518

Alternate gene names: 118581918

Gene position: 3890701-3890183 (Counterclockwise)

Preceding gene: 118581919

Following gene: 118581917

Centisome position: 97.07

GC content: 58.77

Gene sequence:

>519_bases
ATGCAAACAGGTTCAACGTGCCAGTTTACCGGTGGATGCACAACCCCGGGCCGTTCAACGTTACCGGCTACGCTGTGTCA
GGAGTTGGACGACTTTGTCGCCGACCTCCCCACCAGGGAAGGGCATCTGGTAACGGTGCTGCACAAGGCCCAGCAGCTGT
TCGGTTACCTCCCCCGGGAGGTGCAGCAGTACGTTGCCGACCTGATGGGTGTATCGCTGGCCAAGGTCTATGGCGTGGCA
AGTTTCTACACCTTCTTCAGCATGGTTCCCAAGGGGAAATACCCGATCTCCATCTGTATGGGGACTGCCTGCTACGTCAA
GCAGGCCCACAAGATTGTGGACGCGTTCAAGGATATCCTTGGCGTTGAAATCGGAGAGGTTACCGGGGACGGCAAATTCT
CCATCGACGTCCTGCGCTGCGTGGGCGCCTGCGCCCTTGCCCCGATCCTGACGGTGGGCGAGAAGGTCTACGCCCACGTC
ACCCCGGACCAGGTCAAGGAAATTATCGCTGAGTACTGA

Upstream 100 bases:

>100_bases
GGAATACTTCCGCATCAGGCAGGAAGTGCTGAATGCTGATCCGCTGATGTGCAGGAACAGGTCATAACATACGAAACCAC
CAGAAAAGGGATGTACAGAT

Downstream 100 bases:

>100_bases
CCCTTATCCCCAGGGAGTTCACCATGGCAAAGATTACATCCATAGCCGATCTGAAGAAGTTTCAGCAAGAGTACAGGTCA
CTAAAAGAGGCGCGTTCCCG

Product: NADH dehydrogenase (ubiquinone), 24 kDa subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MQTGSTCQFTGGCTTPGRSTLPATLCQELDDFVADLPTREGHLVTVLHKAQQLFGYLPREVQQYVADLMGVSLAKVYGVA
SFYTFFSMVPKGKYPISICMGTACYVKQAHKIVDAFKDILGVEIGEVTGDGKFSIDVLRCVGACALAPILTVGEKVYAHV
TPDQVKEIIAEY

Sequences:

>Translated_172_residues
MQTGSTCQFTGGCTTPGRSTLPATLCQELDDFVADLPTREGHLVTVLHKAQQLFGYLPREVQQYVADLMGVSLAKVYGVA
SFYTFFSMVPKGKYPISICMGTACYVKQAHKIVDAFKDILGVEIGEVTGDGKFSIDVLRCVGACALAPILTVGEKVYAHV
TPDQVKEIIAEY
>Mature_172_residues
MQTGSTCQFTGGCTTPGRSTLPATLCQELDDFVADLPTREGHLVTVLHKAQQLFGYLPREVQQYVADLMGVSLAKVYGVA
SFYTFFSMVPKGKYPISICMGTACYVKQAHKIVDAFKDILGVEIGEVTGDGKFSIDVLRCVGACALAPILTVGEKVYAHV
TPDQVKEIIAEY

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=149, Percent_Identity=34.2281879194631, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI1788621, Length=129, Percent_Identity=28.6821705426357, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561328, Length=131, Percent_Identity=35.1145038167939, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859877, Length=133, Percent_Identity=33.0827067669173, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21355353, Length=132, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18621; Mature: 18621

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTGSTCQFTGGCTTPGRSTLPATLCQELDDFVADLPTREGHLVTVLHKAQQLFGYLPRE
CCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHH
VQQYVADLMGVSLAKVYGVASFYTFFSMVPKGKYPISICMGTACYVKQAHKIVDAFKDIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GVEIGEVTGDGKFSIDVLRCVGACALAPILTVGEKVYAHVTPDQVKEIIAEY
CCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHCC
>Mature Secondary Structure
MQTGSTCQFTGGCTTPGRSTLPATLCQELDDFVADLPTREGHLVTVLHKAQQLFGYLPRE
CCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHH
VQQYVADLMGVSLAKVYGVASFYTFFSMVPKGKYPISICMGTACYVKQAHKIVDAFKDIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GVEIGEVTGDGKFSIDVLRCVGACALAPILTVGEKVYAHVTPDQVKEIIAEY
CCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]