Click here to switch to the map view.

The map label for this gene is ppdK [H]

Identifier: 118581911

GI number: 118581911

Start: 3880749

End: 3883406

Strand: Direct

Name: ppdK [H]

Synonym: Ppro_3511

Alternate gene names: 118581911

Gene position: 3880749-3883406 (Clockwise)

Preceding gene: 118581901

Following gene: 118581915

Centisome position: 96.83

GC content: 62.42

Gene sequence:

>2658_bases
ATGGCGCAGCAATACGTGTATTTCTTTGGTGGCGGCAAGGCTGACGGCCGGGCCGACATGAAAAACCTGCTGGGGGGCAA
GGGTGCCAATCTGGCTGAAATGACCAGCATTGGTCTGCCGGTTCCCCCGGGATTCACGATCTCCACCGAAGTATGTACCG
AATTTTATAAGAACGACCGCACCCATCCTGCGTCCTTGGCTGCCGAAGTGTCCGCCAATCTGAGGAAAATCGAGGAATTG
ATGGGCAAGAAGTTTGGGGATTCCGGAAATCCGCTGCTCCTCTCGGTCCGCTCCGGCGCCCGCGCCTCCATGCCGGGCAT
GATGGATACGGTCCTCAACCTTGGCCTCAACGACACCACCGTCCAGGGGATCATCGCCCAGAGCGGGGACGAGCGTTTCG
CCTACGACGCCTACCGCCGCTTCGTCCAGATGTATGCCGATGTGGTGCTGGGGATGGAAAAGGACATCCTCGACCACCTG
CTGGACCAGAAGAAGGAGGAGCGCGGGGTCTATCTGGACACCGATCTCACCGCCGCCGACTGGAAGGACCTGGTGCTCCA
GTACAAGGGAGCCATCAAGGCCGAGCTTGGCATCGACTTTCCCGAAGATCCGGAAGAGCAGTTGTGGGGAGCGGTGAACG
CGGTGTTCGGCTCCTGGATGAACCAGCGCGCCATCACCTACCGCAAGCTCAACAACATCCCGGCCGAATGGGGCACGGCG
GTCAACGTCCAGGCCATGGTCTTCGGCAACATGGGCCAGGACTGCGCCACCGGCGTGGCCTTCACCCGCGACCCCTCCAC
TGGCGAGAACTACTTTTACGGCGAATTCCTGGTTAATGCCCAGGGAGAGGACGTGGTGGCCGGCATCCGCACCCCCCAGC
CGATCAACCGCGCCAAGAACAAGGATGGCGAGCTTCCCTCCATGGAAGAGGTCATGCCGGAATGCTACCAGCAGCTGGTA
CGCATCCGCGAAACCCTTGAAAAGCATTACCGGGACATGCAGGATATCGAGTTCACCATCGAGAAGGGCGTTCTGTACAT
GCTGCAGACCAGAAACGGCAAGCGCACCGCGCCGGCCGCCATCAAGATCGCCGTGGACATGGTGAACGAGGGGCTGATCG
ACAAGAAGACCGCCGTGCTGCGTGTGGAGCCCAGCCAGCTGGATCAGTTGCTGCACCCCACCCTTGATCCGAAGGCGGAG
AGAACCATCATCGCCAAGGGACTGCCGGCCTCACCCGGAGCGGTTTCCGGTGAAGTGGTCTTCTCGGCCGACGAGGCCGA
GGCCGAGGCCAAGACCGGCCGCAAGGTCATCCTGGTGCGCATCGAAACCTCGCCCGAAGATATCCACGGCATGCACGCCG
CCCAGGGAATCCTCACCGCACGCGGAGGCATGACCTCCCACGCTGCTGTCGTTGCCCGCGGCATGGGCAAATGCTGCGTG
GCCGGCTGCGGCGACATCAAGGTCGACTACGCGGACGAGAGCTTTATCGCACCCAATGGCGTGGAAGTGAAGAAGGGCGA
CCTGATCACCCTGGACGGCGCCACGGGAGAGGTCATGCTGGGTGTGGTGCCCACCGTGTCGGTTCAGCTGACCGGAGATT
TCGCCACACTGATGGGCTGGGTGGACCAGTTCAGAACACTGAAGGTGCGCGCCAACGCCGACACCCCCCATGACGCCCGG
GTGGCCCGGGAATTCGGCGCTCAAGGGATCGGACTCTGCCGCACCGAGCATATGTTCTTCGACGCCGAACGCATCGCAGC
CGTGCGCGAGATGATCCTCTCCGACGACCTGGAGGGCCGCCAGAAAGCACTGGCCAAGATCCTGCCCATGCAGACCAGCG
ATTTCAAGGGGATCTTCCGCGAGATGAAGGGGCTGCCGGTTACTATCCGCCTGCTGGACCCGCCGCTGCACGAGTTCCTC
CCCCAGACCGAGAAGGATATCGATGAACTGGCCGCAACCATGCGGGTGCCCGCCAGCACGCTCAGGCACAAGGTAGAGTA
CCTTCACGAGTTCAACCCCATGCTGGGGCACCGCGGTTGCCGTCTCGGTATTACCTACCCCGAGATTTACGACATGCAGG
TGCGCGCCATCATGGTGGCTGCCTGCGAACTGATCAAGAACAACGGCTTCTCCATCGTACCCGAAATCATGATTCCCCTG
GTGGCAACGGTCAGGGAGTTGGCACTGCTCAAGCGGAACGCCGTAGCGATCTGCGAGGAGGTCATCGCCGACTACGGCGT
CACGATGGAGTACCTGATCGGCACCATGATCGAGCTCCCCCGCGCCGCCCTGACCGCCGACGAGATCGCCAGTGAGGCCG
AATTCTTCTCCTTCGGCACCAACGACCTGACCCAGACCACCTTCGGCCTCTCCCGCGACGATGCGGGCAAATTCCTTCCG
TTCTACATGGATAACGGCATCATCGAGCAGGACCCCTTCGTCTCCCTGGATCAGACAGGCGTCGGCCAGCTGGTCAGGAT
CGCCAGCGAGAAGGGGCGCGCCACCCGGCCGGACATCAAGCTCGGCATCTGCGGCGAGCATGGCGGGGACCCTGCATCGG
TCTGCTTCTGCCACACAAGCGGGCTGGACTACGTCTCCTGCTCACCCTTCCGGGTGCCCATCGCCCGCCTGGCAGCAGCC
CACGCCGCACTCTCCTGA

Upstream 100 bases:

>100_bases
GGCTTGACAGCCGAGTTTGATTGAAATACAAGGTTTTAGTCTAAATAAAAATGGCTGAAAAACGCTTCTATTCAAACACT
GGTGAGGAGGATTTACCGCA

Downstream 100 bases:

>100_bases
GCATCGGGAACAGGGTTGACACAAAAAAAGGATGGACCGGAAACGGTTCATCCTTTTTTTATGCGCCAGGCAAGGGGGAG
CGGCTATCCCTCCCCGAACA

Product: pyruvate phosphate dikinase

Products: NA

Alternate protein names: Pyruvate, orthophosphate dikinase [H]

Number of amino acids: Translated: 885; Mature: 884

Protein sequence:

>885_residues
MAQQYVYFFGGGKADGRADMKNLLGGKGANLAEMTSIGLPVPPGFTISTEVCTEFYKNDRTHPASLAAEVSANLRKIEEL
MGKKFGDSGNPLLLSVRSGARASMPGMMDTVLNLGLNDTTVQGIIAQSGDERFAYDAYRRFVQMYADVVLGMEKDILDHL
LDQKKEERGVYLDTDLTAADWKDLVLQYKGAIKAELGIDFPEDPEEQLWGAVNAVFGSWMNQRAITYRKLNNIPAEWGTA
VNVQAMVFGNMGQDCATGVAFTRDPSTGENYFYGEFLVNAQGEDVVAGIRTPQPINRAKNKDGELPSMEEVMPECYQQLV
RIRETLEKHYRDMQDIEFTIEKGVLYMLQTRNGKRTAPAAIKIAVDMVNEGLIDKKTAVLRVEPSQLDQLLHPTLDPKAE
RTIIAKGLPASPGAVSGEVVFSADEAEAEAKTGRKVILVRIETSPEDIHGMHAAQGILTARGGMTSHAAVVARGMGKCCV
AGCGDIKVDYADESFIAPNGVEVKKGDLITLDGATGEVMLGVVPTVSVQLTGDFATLMGWVDQFRTLKVRANADTPHDAR
VAREFGAQGIGLCRTEHMFFDAERIAAVREMILSDDLEGRQKALAKILPMQTSDFKGIFREMKGLPVTIRLLDPPLHEFL
PQTEKDIDELAATMRVPASTLRHKVEYLHEFNPMLGHRGCRLGITYPEIYDMQVRAIMVAACELIKNNGFSIVPEIMIPL
VATVRELALLKRNAVAICEEVIADYGVTMEYLIGTMIELPRAALTADEIASEAEFFSFGTNDLTQTTFGLSRDDAGKFLP
FYMDNGIIEQDPFVSLDQTGVGQLVRIASEKGRATRPDIKLGICGEHGGDPASVCFCHTSGLDYVSCSPFRVPIARLAAA
HAALS

Sequences:

>Translated_885_residues
MAQQYVYFFGGGKADGRADMKNLLGGKGANLAEMTSIGLPVPPGFTISTEVCTEFYKNDRTHPASLAAEVSANLRKIEEL
MGKKFGDSGNPLLLSVRSGARASMPGMMDTVLNLGLNDTTVQGIIAQSGDERFAYDAYRRFVQMYADVVLGMEKDILDHL
LDQKKEERGVYLDTDLTAADWKDLVLQYKGAIKAELGIDFPEDPEEQLWGAVNAVFGSWMNQRAITYRKLNNIPAEWGTA
VNVQAMVFGNMGQDCATGVAFTRDPSTGENYFYGEFLVNAQGEDVVAGIRTPQPINRAKNKDGELPSMEEVMPECYQQLV
RIRETLEKHYRDMQDIEFTIEKGVLYMLQTRNGKRTAPAAIKIAVDMVNEGLIDKKTAVLRVEPSQLDQLLHPTLDPKAE
RTIIAKGLPASPGAVSGEVVFSADEAEAEAKTGRKVILVRIETSPEDIHGMHAAQGILTARGGMTSHAAVVARGMGKCCV
AGCGDIKVDYADESFIAPNGVEVKKGDLITLDGATGEVMLGVVPTVSVQLTGDFATLMGWVDQFRTLKVRANADTPHDAR
VAREFGAQGIGLCRTEHMFFDAERIAAVREMILSDDLEGRQKALAKILPMQTSDFKGIFREMKGLPVTIRLLDPPLHEFL
PQTEKDIDELAATMRVPASTLRHKVEYLHEFNPMLGHRGCRLGITYPEIYDMQVRAIMVAACELIKNNGFSIVPEIMIPL
VATVRELALLKRNAVAICEEVIADYGVTMEYLIGTMIELPRAALTADEIASEAEFFSFGTNDLTQTTFGLSRDDAGKFLP
FYMDNGIIEQDPFVSLDQTGVGQLVRIASEKGRATRPDIKLGICGEHGGDPASVCFCHTSGLDYVSCSPFRVPIARLAAA
HAALS
>Mature_884_residues
AQQYVYFFGGGKADGRADMKNLLGGKGANLAEMTSIGLPVPPGFTISTEVCTEFYKNDRTHPASLAAEVSANLRKIEELM
GKKFGDSGNPLLLSVRSGARASMPGMMDTVLNLGLNDTTVQGIIAQSGDERFAYDAYRRFVQMYADVVLGMEKDILDHLL
DQKKEERGVYLDTDLTAADWKDLVLQYKGAIKAELGIDFPEDPEEQLWGAVNAVFGSWMNQRAITYRKLNNIPAEWGTAV
NVQAMVFGNMGQDCATGVAFTRDPSTGENYFYGEFLVNAQGEDVVAGIRTPQPINRAKNKDGELPSMEEVMPECYQQLVR
IRETLEKHYRDMQDIEFTIEKGVLYMLQTRNGKRTAPAAIKIAVDMVNEGLIDKKTAVLRVEPSQLDQLLHPTLDPKAER
TIIAKGLPASPGAVSGEVVFSADEAEAEAKTGRKVILVRIETSPEDIHGMHAAQGILTARGGMTSHAAVVARGMGKCCVA
GCGDIKVDYADESFIAPNGVEVKKGDLITLDGATGEVMLGVVPTVSVQLTGDFATLMGWVDQFRTLKVRANADTPHDARV
AREFGAQGIGLCRTEHMFFDAERIAAVREMILSDDLEGRQKALAKILPMQTSDFKGIFREMKGLPVTIRLLDPPLHEFLP
QTEKDIDELAATMRVPASTLRHKVEYLHEFNPMLGHRGCRLGITYPEIYDMQVRAIMVAACELIKNNGFSIVPEIMIPLV
ATVRELALLKRNAVAICEEVIADYGVTMEYLIGTMIELPRAALTADEIASEAEFFSFGTNDLTQTTFGLSRDDAGKFLPF
YMDNGIIEQDPFVSLDQTGVGQLVRIASEKGRATRPDIKLGICGEHGGDPASVCFCHTSGLDYVSCSPFRVPIARLAAAH
AALS

Specific function: Catalyzes the reversible phosphorylation of pyruvate and phosphate [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1788756, Length=459, Percent_Identity=26.3616557734205, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1789193, Length=429, Percent_Identity=24.9417249417249, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1788726, Length=335, Percent_Identity=25.9701492537313, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI48994992, Length=436, Percent_Identity=23.1651376146789, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2659 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR010121
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.1 [H]

Molecular weight: Translated: 96777; Mature: 96646

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQQYVYFFGGGKADGRADMKNLLGGKGANLAEMTSIGLPVPPGFTISTEVCTEFYKNDR
CCCEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEHHHHHHHHHHCCC
THPASLAAEVSANLRKIEELMGKKFGDSGNPLLLSVRSGARASMPGMMDTVLNLGLNDTT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCHH
VQGIIAQSGDERFAYDAYRRFVQMYADVVLGMEKDILDHLLDQKKEERGVYLDTDLTAAD
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECCCCHHH
WKDLVLQYKGAIKAELGIDFPEDPEEQLWGAVNAVFGSWMNQRAITYRKLNNIPAEWGTA
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCE
VNVQAMVFGNMGQDCATGVAFTRDPSTGENYFYGEFLVNAQGEDVVAGIRTPQPINRAKN
EEEEEEEECCCCCHHHCCCEEECCCCCCCCEEEEEEEEECCCCCEEEECCCCCCHHHCCC
KDGELPSMEEVMPECYQQLVRIRETLEKHYRDMQDIEFTIEKGVLYMLQTRNGKRTAPAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEECCCCCCCCCE
IKIAVDMVNEGLIDKKTAVLRVEPSQLDQLLHPTLDPKAERTIIAKGLPASPGAVSGEVV
EEEEHHHHHCCCCCCCCEEEEECHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCEE
FSADEAEAEAKTGRKVILVRIETSPEDIHGMHAAQGILTARGGMTSHAAVVARGMGKCCV
EECCHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHEECCCCCHHHHHHHHCCCCCEE
AGCGDIKVDYADESFIAPNGVEVKKGDLITLDGATGEVMLGVVPTVSVQLTGDFATLMGW
ECCCCEEEEECCCCCCCCCCCEEECCCEEEECCCCCCEEEEEECEEEEEECCCHHHHHHH
VDQFRTLKVRANADTPHDARVAREFGAQGIGLCRTEHMFFDAERIAAVREMILSDDLEGR
HHHHEEEEEEECCCCCHHHHHHHHHCCCCCCEEEHHHHHCCHHHHHHHHHHHHCCCCCHH
QKALAKILPMQTSDFKGIFREMKGLPVTIRLLDPPLHEFLPQTEKDIDELAATMRVPAST
HHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHCCCCHHHHHHHHHHHCCCHHH
LRHKVEYLHEFNPMLGHRGCRLGITYPEIYDMQVRAIMVAACELIKNNGFSIVPEIMIPL
HHHHHHHHHHCCHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
VATVRELALLKRNAVAICEEVIADYGVTMEYLIGTMIELPRAALTADEIASEAEFFSFGT
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
NDLTQTTFGLSRDDAGKFLPFYMDNGIIEQDPFVSLDQTGVGQLVRIASEKGRATRPDIK
CCHHHHHCCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEE
LGICGEHGGDPASVCFCHTSGLDYVSCSPFRVPIARLAAAHAALS
EEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQQYVYFFGGGKADGRADMKNLLGGKGANLAEMTSIGLPVPPGFTISTEVCTEFYKNDR
CCEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEHHHHHHHHHHCCC
THPASLAAEVSANLRKIEELMGKKFGDSGNPLLLSVRSGARASMPGMMDTVLNLGLNDTT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCHH
VQGIIAQSGDERFAYDAYRRFVQMYADVVLGMEKDILDHLLDQKKEERGVYLDTDLTAAD
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECCCCHHH
WKDLVLQYKGAIKAELGIDFPEDPEEQLWGAVNAVFGSWMNQRAITYRKLNNIPAEWGTA
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCE
VNVQAMVFGNMGQDCATGVAFTRDPSTGENYFYGEFLVNAQGEDVVAGIRTPQPINRAKN
EEEEEEEECCCCCHHHCCCEEECCCCCCCCEEEEEEEEECCCCCEEEECCCCCCHHHCCC
KDGELPSMEEVMPECYQQLVRIRETLEKHYRDMQDIEFTIEKGVLYMLQTRNGKRTAPAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEECCCCCCCCCE
IKIAVDMVNEGLIDKKTAVLRVEPSQLDQLLHPTLDPKAERTIIAKGLPASPGAVSGEVV
EEEEHHHHHCCCCCCCCEEEEECHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCEE
FSADEAEAEAKTGRKVILVRIETSPEDIHGMHAAQGILTARGGMTSHAAVVARGMGKCCV
EECCHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHEECCCCCHHHHHHHHCCCCCEE
AGCGDIKVDYADESFIAPNGVEVKKGDLITLDGATGEVMLGVVPTVSVQLTGDFATLMGW
ECCCCEEEEECCCCCCCCCCCEEECCCEEEECCCCCCEEEEEECEEEEEECCCHHHHHHH
VDQFRTLKVRANADTPHDARVAREFGAQGIGLCRTEHMFFDAERIAAVREMILSDDLEGR
HHHHEEEEEEECCCCCHHHHHHHHHCCCCCCEEEHHHHHCCHHHHHHHHHHHHCCCCCHH
QKALAKILPMQTSDFKGIFREMKGLPVTIRLLDPPLHEFLPQTEKDIDELAATMRVPAST
HHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHCCCCHHHHHHHHHHHCCCHHH
LRHKVEYLHEFNPMLGHRGCRLGITYPEIYDMQVRAIMVAACELIKNNGFSIVPEIMIPL
HHHHHHHHHHCCHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
VATVRELALLKRNAVAICEEVIADYGVTMEYLIGTMIELPRAALTADEIASEAEFFSFGT
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
NDLTQTTFGLSRDDAGKFLPFYMDNGIIEQDPFVSLDQTGVGQLVRIASEKGRATRPDIK
CCHHHHHCCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEE
LGICGEHGGDPASVCFCHTSGLDYVSCSPFRVPIARLAAAHAALS
EEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9168612 [H]