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The map label for this gene is cobL [H]

Identifier: 118581903

GI number: 118581903

Start: 3871965

End: 3873185

Strand: Reverse

Name: cobL [H]

Synonym: Ppro_3503

Alternate gene names: 118581903

Gene position: 3873185-3871965 (Counterclockwise)

Preceding gene: 118581904

Following gene: 118581902

Centisome position: 96.64

GC content: 61.02

Gene sequence:

>1221_bases
ATGGCACAGCACAAGATATATCTGGTCGGCGCCGGCATCGAGGGGTGGGAGGGGTTCAGCTCCACCGCACTGGCGGTTAT
CGACAAGACCGAGGTCATGATCGGCCATCAGCGGCACCTGGACATCTTTCCCGCCTATGGCGGCAGCAAGATGGTTTTGG
GACCGCTCTCCGAGCTGCTGGAGTTCCTGAGGGAAACGGAGAAACGGGTGGTCATACTGGCCTCCGGCGACCCGAACTTC
TTCGGTATCTCCCGCTTCCTGCTGCGTAACCTGCCCAAGGAGCGCATTGCCATCTTCGCTAACGTCACCAGCATGCAGTA
TGCCTTTTCGCGCATCAAGGAGCCCTGGGACGACGCCATCTTCGTATCGGCACATGGCAGGGGGCTGCATGCGGCGGTGG
ACAAGATCGTGGCTTCCGAGAAGGCCTGCGTCCTGACCGACAAGGTCAACACCCCCGCCGCCATCGCGCGGGAGATGATC
GAGCGGGGCGCCGAAGGGTATGAGGCTTGGCTGTGCGAAGACCTGGGGCTGGACAGTGAAAAATTCACCCGCACCGACGT
GCGCGGCCTGCTGGAGCTTAAAGCCTCCGACCTGAATATCCTGATCCTGATCAAGACCTATGAACCGAACCTGGTGCAGT
ATCCGCTGATCGGCATCGCCGACGACGAGTTCCAGACCGTCAAGAAGCTGATCACCAAGCAGGAGGTGCGGGCGGTCACC
CTGGCCAAACTGCAGATCCAGGACGACCTGGTGATGTGGGACATCGGCGCGGGGAGCGGCTCCGTGTCCATCGAGGCCTC
CAACCTGATGCCCAACGGCCGTATCTTCGCCCTGGAGCGCAACCCGGCCTGCGTCGGCTATATCCAGGAGAACCTGAAGA
AATTCTGCGCCCGCAATGTCAAGCTGATCGAGGCCTATGCCCCGGAAGGGCTGGACGAACTGCCCGATCCGGACCGGGTG
TTCATCGGCGGAGCAGGCGGGCAGCTTGAGGATATCATCGATGCGGTGGACAGGCGCCTCAAGCCGGAAGGATTGATCGT
GCTGAACGCGGTCACCCTGGATACCCTGGCCAAGTCGGTGGAATACCTGGAGGACCATGGCTACGACGTGGCGGCCAGTT
GCGTCAACATCTCCAGAACCCGTAAGCTGACCGAGTTCAAGCTGTTCGAAGCCCAGAACCCGGTCTACATCATCACAGCC
CACAAGGGGAGCACACACTGA

Upstream 100 bases:

>100_bases
AGCAACACTTCCAAACGCCCGCCCATTCTTGCGGTGATTTTTCCCCCGTGAGATGCTATAGTGTCCGCGTTTGACTCACT
AACCCATCTGGGGCTACTAC

Downstream 100 bases:

>100_bases
TGGCAACACTCTTTGCAGTTGGAGTCGGTCCGGGTGATCCGGAACTCCTGACGAGAAAGGCAGAGCGCATCCTGCGCCAG
GCCGATGTGATCCTGGCACC

Product: precorrin-6y C5,15-methyltransferase subunit CbiE

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MAQHKIYLVGAGIEGWEGFSSTALAVIDKTEVMIGHQRHLDIFPAYGGSKMVLGPLSELLEFLRETEKRVVILASGDPNF
FGISRFLLRNLPKERIAIFANVTSMQYAFSRIKEPWDDAIFVSAHGRGLHAAVDKIVASEKACVLTDKVNTPAAIAREMI
ERGAEGYEAWLCEDLGLDSEKFTRTDVRGLLELKASDLNILILIKTYEPNLVQYPLIGIADDEFQTVKKLITKQEVRAVT
LAKLQIQDDLVMWDIGAGSGSVSIEASNLMPNGRIFALERNPACVGYIQENLKKFCARNVKLIEAYAPEGLDELPDPDRV
FIGGAGGQLEDIIDAVDRRLKPEGLIVLNAVTLDTLAKSVEYLEDHGYDVAASCVNISRTRKLTEFKLFEAQNPVYIITA
HKGSTH

Sequences:

>Translated_406_residues
MAQHKIYLVGAGIEGWEGFSSTALAVIDKTEVMIGHQRHLDIFPAYGGSKMVLGPLSELLEFLRETEKRVVILASGDPNF
FGISRFLLRNLPKERIAIFANVTSMQYAFSRIKEPWDDAIFVSAHGRGLHAAVDKIVASEKACVLTDKVNTPAAIAREMI
ERGAEGYEAWLCEDLGLDSEKFTRTDVRGLLELKASDLNILILIKTYEPNLVQYPLIGIADDEFQTVKKLITKQEVRAVT
LAKLQIQDDLVMWDIGAGSGSVSIEASNLMPNGRIFALERNPACVGYIQENLKKFCARNVKLIEAYAPEGLDELPDPDRV
FIGGAGGQLEDIIDAVDRRLKPEGLIVLNAVTLDTLAKSVEYLEDHGYDVAASCVNISRTRKLTEFKLFEAQNPVYIITA
HKGSTH
>Mature_405_residues
AQHKIYLVGAGIEGWEGFSSTALAVIDKTEVMIGHQRHLDIFPAYGGSKMVLGPLSELLEFLRETEKRVVILASGDPNFF
GISRFLLRNLPKERIAIFANVTSMQYAFSRIKEPWDDAIFVSAHGRGLHAAVDKIVASEKACVLTDKVNTPAAIAREMIE
RGAEGYEAWLCEDLGLDSEKFTRTDVRGLLELKASDLNILILIKTYEPNLVQYPLIGIADDEFQTVKKLITKQEVRAVTL
AKLQIQDDLVMWDIGAGSGSVSIEASNLMPNGRIFALERNPACVGYIQENLKKFCARNVKLIEAYAPEGLDELPDPDRVF
IGGAGGQLEDIIDAVDRRLKPEGLIVLNAVTLDTLAKSVEYLEDHGYDVAASCVNISRTRKLTEFKLFEAQNPVYIITAH
KGSTH

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 44906; Mature: 44775

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQHKIYLVGAGIEGWEGFSSTALAVIDKTEVMIGHQRHLDIFPAYGGSKMVLGPLSELL
CCCEEEEEEECCCCCCCCCCCCEEEEEECCEEEECCCCCEEEEECCCCCEEEHHHHHHHH
EFLRETEKRVVILASGDPNFFGISRFLLRNLPKERIAIFANVTSMQYAFSRIKEPWDDAI
HHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHEEEEEEHHHHHHHHHHHCCCCCCEE
FVSAHGRGLHAAVDKIVASEKACVLTDKVNTPAAIAREMIERGAEGYEAWLCEDLGLDSE
EEEECCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCHH
KFTRTDVRGLLELKASDLNILILIKTYEPNLVQYPLIGIADDEFQTVKKLITKQEVRAVT
HHHHHHHHHHHHEECCCCEEEEEEEECCCCEEEECEEEECCHHHHHHHHHHHHHHHHEEE
LAKLQIQDDLVMWDIGAGSGSVSIEASNLMPNGRIFALERNPACVGYIQENLKKFCARNV
EEEEEEECCEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCEEHHHHHHHHHHHHCCE
KLIEAYAPEGLDELPDPDRVFIGGAGGQLEDIIDAVDRRLKPEGLIVLNAVTLDTLAKSV
EEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHH
EYLEDHGYDVAASCVNISRTRKLTEFKLFEAQNPVYIITAHKGSTH
HHHHHCCCCHHHHHHHHHHHCCHHEEEEEECCCCEEEEEECCCCCC
>Mature Secondary Structure 
AQHKIYLVGAGIEGWEGFSSTALAVIDKTEVMIGHQRHLDIFPAYGGSKMVLGPLSELL
CCEEEEEEECCCCCCCCCCCCEEEEEECCEEEECCCCCEEEEECCCCCEEEHHHHHHHH
EFLRETEKRVVILASGDPNFFGISRFLLRNLPKERIAIFANVTSMQYAFSRIKEPWDDAI
HHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHEEEEEEHHHHHHHHHHHCCCCCCEE
FVSAHGRGLHAAVDKIVASEKACVLTDKVNTPAAIAREMIERGAEGYEAWLCEDLGLDSE
EEEECCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCHH
KFTRTDVRGLLELKASDLNILILIKTYEPNLVQYPLIGIADDEFQTVKKLITKQEVRAVT
HHHHHHHHHHHHEECCCCEEEEEEEECCCCEEEECEEEECCHHHHHHHHHHHHHHHHEEE
LAKLQIQDDLVMWDIGAGSGSVSIEASNLMPNGRIFALERNPACVGYIQENLKKFCARNV
EEEEEEECCEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCEEHHHHHHHHHHHHCCE
KLIEAYAPEGLDELPDPDRVFIGGAGGQLEDIIDAVDRRLKPEGLIVLNAVTLDTLAKSV
EEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHH
EYLEDHGYDVAASCVNISRTRKLTEFKLFEAQNPVYIITAHKGSTH
HHHHHCCCCHHHHHHHHHHHCCHHEEEEEECCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]