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The map label for this gene is cbiL [H]

Identifier: 118581902

GI number: 118581902

Start: 3871261

End: 3871965

Strand: Reverse

Name: cbiL [H]

Synonym: Ppro_3502

Alternate gene names: 118581902

Gene position: 3871965-3871261 (Counterclockwise)

Preceding gene: 118581903

Following gene: 118581900

Centisome position: 96.61

GC content: 61.84

Gene sequence:

>705_bases
ATGGCAACACTCTTTGCAGTTGGAGTCGGTCCGGGTGATCCGGAACTCCTGACGAGAAAGGCAGAGCGCATCCTGCGCCA
GGCCGATGTGATCCTGGCACCGGTATCGCACCCCGGCGACGCCAGCGTGGCCCATGAAACGGTGCGGGAATTCGTGGATG
AGACCCGCCAGGAACTGATCATCCATCAGTTCCCCATGACGTCGGACAAATCGCGGCTGATCCCGGCCTGGCAGGAGGCT
GCGGCACTCATGGCCGAGCGGATTCAGGCGGGCAAGGACGTGGCCTTCATAACCATCGGCGACCCCCTGCTCTACTCCAC
CTTCATCTACCTGCTGCGCATCTTCCGCGAGAGCTACCCCGCACTCCCGGTGGAGATCGTTCCGGGCATATCCAGCATCA
ATACCGCCGCTGCCGTGGCGGGAGTGCCCCTGGCCGAGGCAGAGGAGAAGATCGTGGTCATTCCGGCCACGGCCGGTATC
GAGGCGATAGCTAGTGCGCTGCAGGAGTTCGAAACAGTGGTGTTGCTGAAGGTCAAGCCGCTCTACGCCGATATTCTGAA
GCTGCTGAAGGAGACCGGACGCTCGGAGAGTGCGCTGTTCGTGGAACGGGTCGGCAGCGCCCGCCAGAAAATTCTGACCG
GCATCGATGCCATGGCCACCCATACCCCCGACTACCTGTCGCTGATGATCATCAGGAAACCGTAG

Upstream 100 bases:

>100_bases
GCGTCAACATCTCCAGAACCCGTAAGCTGACCGAGTTCAAGCTGTTCGAAGCCCAGAACCCGGTCTACATCATCACAGCC
CACAAGGGGAGCACACACTG

Downstream 100 bases:

>100_bases
CTTTTCACCAGAACCGCAACGCACAACGCCCCTCCGGTGTTTCATCCGGAGGGGCGTTGTGTTTCGTTCTTGTCCGCAGG
GCGCTCTTCTACTTGCTCTC

Product: precorrin-2 C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MATLFAVGVGPGDPELLTRKAERILRQADVILAPVSHPGDASVAHETVREFVDETRQELIIHQFPMTSDKSRLIPAWQEA
AALMAERIQAGKDVAFITIGDPLLYSTFIYLLRIFRESYPALPVEIVPGISSINTAAAVAGVPLAEAEEKIVVIPATAGI
EAIASALQEFETVVLLKVKPLYADILKLLKETGRSESALFVERVGSARQKILTGIDAMATHTPDYLSLMIIRKP

Sequences:

>Translated_234_residues
MATLFAVGVGPGDPELLTRKAERILRQADVILAPVSHPGDASVAHETVREFVDETRQELIIHQFPMTSDKSRLIPAWQEA
AALMAERIQAGKDVAFITIGDPLLYSTFIYLLRIFRESYPALPVEIVPGISSINTAAAVAGVPLAEAEEKIVVIPATAGI
EAIASALQEFETVVLLKVKPLYADILKLLKETGRSESALFVERVGSARQKILTGIDAMATHTPDYLSLMIIRKP
>Mature_233_residues
ATLFAVGVGPGDPELLTRKAERILRQADVILAPVSHPGDASVAHETVREFVDETRQELIIHQFPMTSDKSRLIPAWQEAA
ALMAERIQAGKDVAFITIGDPLLYSTFIYLLRIFRESYPALPVEIVPGISSINTAAAVAGVPLAEAEEKIVVIPATAGIE
AIASALQEFETVVLLKVKPLYADILKLLKETGRSESALFVERVGSARQKILTGIDAMATHTPDYLSLMIIRKP

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 25424; Mature: 25293

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLFAVGVGPGDPELLTRKAERILRQADVILAPVSHPGDASVAHETVREFVDETRQELI
CCEEEEEECCCCCHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
IHQFPMTSDKSRLIPAWQEAAALMAERIQAGKDVAFITIGDPLLYSTFIYLLRIFRESYP
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCC
ALPVEIVPGISSINTAAAVAGVPLAEAEEKIVVIPATAGIEAIASALQEFETVVLLKVKP
CCCEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHEEEEEECH
LYADILKLLKETGRSESALFVERVGSARQKILTGIDAMATHTPDYLSLMIIRKP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
>Mature Secondary Structure 
ATLFAVGVGPGDPELLTRKAERILRQADVILAPVSHPGDASVAHETVREFVDETRQELI
CEEEEEECCCCCHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
IHQFPMTSDKSRLIPAWQEAAALMAERIQAGKDVAFITIGDPLLYSTFIYLLRIFRESYP
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCC
ALPVEIVPGISSINTAAAVAGVPLAEAEEKIVVIPATAGIEAIASALQEFETVVLLKVKP
CCCEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHEEEEEECH
LYADILKLLKETGRSESALFVERVGSARQKILTGIDAMATHTPDYLSLMIIRKP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]