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The map label for this gene is bioD [C]

Identifier: 118581873

GI number: 118581873

Start: 3836336

End: 3837427

Strand: Reverse

Name: bioD [C]

Synonym: Ppro_3473

Alternate gene names: 118581873

Gene position: 3837427-3836336 (Counterclockwise)

Preceding gene: 118581878

Following gene: 118581872

Centisome position: 95.74

GC content: 59.25

Gene sequence:

>1092_bases
ATGTGCAAGAAAATCTTCATCGGCGCAACCGGCCAGCACTGCGGAAAAACAACCATCAGCCTCTCCCTGATGCATCTGGC
GGCGAAGAAATACCGCAGGGTCGGCTTTGTTAAGCCCATCGGCCCCAAATGCGTGGAGTACCGCGGGGTGTGCATGGATA
TCGACGCAGCCCTGATCGCCAGCGTCTTTCATCTTGACGAGGACCTGGGCCTCATGTCCCCCATGACACTCTCTTCGGGA
AGTACGCGGCGCTACCTGGATGGCGACATCCCCGCCGACTATCCGCGCCGGACCATCCTGGCGGCCATTGCCGAGTTGGA
GAAGCGGCACGATTTCCTGATCATCGAGGGGGCTGGCCATACCGGTGTCGGCTCTGTTCTCGGCATGAGCAACGCCACCA
TTGCCGCCCAGATCGGTGCTCCGGTGCTGCTGGTGACCGGATGCGGCATCGGCAGGGTCATTGACGAGGTGGAGCTCAAC
CTGGCCCTGTACCGGGAGGCGCGGGCCAGGGTCGAATTCATCATGCTCAACAAGATGGAGCCGGACAAGAAGGAGCGTTC
CCTCACCTATATCCGCAAGGCCTTTGCCCGTGAAAAGCTGAGCGTAACCACCGCCTTTGATTTTATTCCCGTTCTTGCTC
ATCCCACGCTCCAGCAGGTATCGGACCTTTTGCAGCTGCCGCTGATGGGGGATCAGGAAGACCACAGCCGCATCTGCCAT
ACCATCCAGCTTGGCTCCGCCTCATGCCAGCGCGTCATCGACCTCTTGGGAGAGTCGACGCTGCTGGTCGTCAACAGTTC
CCGCGACGAACTGGTCGTGACCGCATCCTCGCTGCACCACATACCCGATTTCAAGAAACGCTTGGCCGGCCTGGTCGTCT
GTGGGTACGCCCCCATGTCCGCCATCACCAGGCGGATCATGGAGGACAGCAATATCCCCTATTTCCGGGTCAAGGACCTC
TCGGCCGAGGTGTTCATCAGCCTGCGGGAGTACGTCTCCAAGATTGGCCCGGACGACAGGGAGAAGATTGAACTGATCAA
CACGATTGCCGAACAGTACATTGACTTCGATGCCATTGATGCCATGCTCTGA

Upstream 100 bases:

>100_bases
CCTGCGTTTTCTCAGCGGTGGGGAATAGTACCGGCTTCACTGCGAACTGATGGCGAACCCCGGCCGCCCCTGAACCAGCA
ACCGGCGAGGACACAACCCT

Downstream 100 bases:

>100_bases
AAACGGCGTTGCGGGCGTCAAAAAACGCTTGACCTCACGGACTGTTTGCTATTTATAGAATAGCGTGACAAAAGACTACG
CTTCGCTGGTGACGACATGA

Product: cobyrinic acid a,c-diamide synthase family protein

Products: ADP; Dethiobiotin; H+; Phosphate [C]

Alternate protein names: Cobyrinic Acid A C-Diamide Synthase Family Protein; DRTGG Domain Protein; Phosphotransacetylase Domain-Containing Protein; BioD/DRTGG Domain-Containing Protein; Dethiobiotin Synthase; DRTGG Domain-Containing Protein

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MCKKIFIGATGQHCGKTTISLSLMHLAAKKYRRVGFVKPIGPKCVEYRGVCMDIDAALIASVFHLDEDLGLMSPMTLSSG
STRRYLDGDIPADYPRRTILAAIAELEKRHDFLIIEGAGHTGVGSVLGMSNATIAAQIGAPVLLVTGCGIGRVIDEVELN
LALYREARARVEFIMLNKMEPDKKERSLTYIRKAFAREKLSVTTAFDFIPVLAHPTLQQVSDLLQLPLMGDQEDHSRICH
TIQLGSASCQRVIDLLGESTLLVVNSSRDELVVTASSLHHIPDFKKRLAGLVVCGYAPMSAITRRIMEDSNIPYFRVKDL
SAEVFISLREYVSKIGPDDREKIELINTIAEQYIDFDAIDAML

Sequences:

>Translated_363_residues
MCKKIFIGATGQHCGKTTISLSLMHLAAKKYRRVGFVKPIGPKCVEYRGVCMDIDAALIASVFHLDEDLGLMSPMTLSSG
STRRYLDGDIPADYPRRTILAAIAELEKRHDFLIIEGAGHTGVGSVLGMSNATIAAQIGAPVLLVTGCGIGRVIDEVELN
LALYREARARVEFIMLNKMEPDKKERSLTYIRKAFAREKLSVTTAFDFIPVLAHPTLQQVSDLLQLPLMGDQEDHSRICH
TIQLGSASCQRVIDLLGESTLLVVNSSRDELVVTASSLHHIPDFKKRLAGLVVCGYAPMSAITRRIMEDSNIPYFRVKDL
SAEVFISLREYVSKIGPDDREKIELINTIAEQYIDFDAIDAML
>Mature_363_residues
MCKKIFIGATGQHCGKTTISLSLMHLAAKKYRRVGFVKPIGPKCVEYRGVCMDIDAALIASVFHLDEDLGLMSPMTLSSG
STRRYLDGDIPADYPRRTILAAIAELEKRHDFLIIEGAGHTGVGSVLGMSNATIAAQIGAPVLLVTGCGIGRVIDEVELN
LALYREARARVEFIMLNKMEPDKKERSLTYIRKAFAREKLSVTTAFDFIPVLAHPTLQQVSDLLQLPLMGDQEDHSRICH
TIQLGSASCQRVIDLLGESTLLVVNSSRDELVVTASSLHHIPDFKKRLAGLVVCGYAPMSAITRRIMEDSNIPYFRVKDL
SAEVFISLREYVSKIGPDDREKIELINTIAEQYIDFDAIDAML

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0857

COG function: function code R; BioD-like N-terminal domain of phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 6.3.3.3 [C]

Molecular weight: Translated: 40109; Mature: 40109

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKKIFIGATGQHCGKTTISLSLMHLAAKKYRRVGFVKPIGPKCVEYRGVCMDIDAALIA
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCEEEECHHHHHH
SVFHLDEDLGLMSPMTLSSGSTRRYLDGDIPADYPRRTILAAIAELEKRHDFLIIEGAGH
HHHHCCCCCCCCCCCEECCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCC
TGVGSVLGMSNATIAAQIGAPVLLVTGCGIGRVIDEVELNLALYREARARVEFIMLNKME
CCCHHHHCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCC
PDKKERSLTYIRKAFAREKLSVTTAFDFIPVLAHPTLQQVSDLLQLPLMGDQEDHSRICH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHH
TIQLGSASCQRVIDLLGESTLLVVNSSRDELVVTASSLHHIPDFKKRLAGLVVCGYAPMS
HEECCCHHHHHHHHHHCCCEEEEEECCCCCEEEEHHHHHCCCHHHHHHHHEEEECCCCHH
AITRRIMEDSNIPYFRVKDLSAEVFISLREYVSKIGPDDREKIELINTIAEQYIDFDAID
HHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHH
AML
HCC
>Mature Secondary Structure
MCKKIFIGATGQHCGKTTISLSLMHLAAKKYRRVGFVKPIGPKCVEYRGVCMDIDAALIA
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCEEEECHHHHHH
SVFHLDEDLGLMSPMTLSSGSTRRYLDGDIPADYPRRTILAAIAELEKRHDFLIIEGAGH
HHHHCCCCCCCCCCCEECCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCC
TGVGSVLGMSNATIAAQIGAPVLLVTGCGIGRVIDEVELNLALYREARARVEFIMLNKME
CCCHHHHCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCC
PDKKERSLTYIRKAFAREKLSVTTAFDFIPVLAHPTLQQVSDLLQLPLMGDQEDHSRICH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHH
TIQLGSASCQRVIDLLGESTLLVVNSSRDELVVTASSLHHIPDFKKRLAGLVVCGYAPMS
HEECCCHHHHHHHHHHCCCEEEEEECCCCCEEEEHHHHHCCCHHHHHHHHEEEECCCCHH
AITRRIMEDSNIPYFRVKDLSAEVFISLREYVSKIGPDDREKIELINTIAEQYIDFDAID
HHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHH
AML
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Mg2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.045 {7,8-diaminononanoate}} 40 {MgCl2}} 0.42 {ATP}} 10 {HCO3-}} [C]

Substrates: ATP; CO2; 7,8-Diaminononanoate [C]

Specific reaction: ATP + CO2 + 7,8-Diaminononanoate <==> ADP + Dethiobiotin + (3) H+ + Phosphate [C]

General reaction: Carboxylation; Heteroatomic ring closure [C]

Inhibitor: Ag+; Cd2+; Co2+; Cu2+; Hg2+; Ni2+ [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA