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The map label for this gene is celB [H]

Identifier: 118581818

GI number: 118581818

Start: 3780855

End: 3782291

Strand: Direct

Name: celB [H]

Synonym: Ppro_3418

Alternate gene names: 118581818

Gene position: 3780855-3782291 (Clockwise)

Preceding gene: 118581817

Following gene: 118581819

Centisome position: 94.33

GC content: 60.75

Gene sequence:

>1437_bases
ATGCGGATCAAGTTTGGGACCGATGGCTGGCGTGGCGTGATCGCCCGTGATTTTACCTTTGACAACCTCTCTCTGGTGGC
CCAGGCCACCATGGATTACCTCATTCAAACCAATGCGGCCGGCAGGGGATTGGTAGTCGGTTACGACCGTCGCTTCCTGT
CCCGCGAATTCGCCCGTCGGGTGGCCGAGATCGCCGCAGGCAACGCCATCAGGGTGAGGCTGAGTGACGGCTATGCACCA
ACTCCGGCCATTTCCTGGGCAGTGCGGGAGAGCGGAGCAGGAGCGGGCATAATGGTCACCGCCAGTCATAATCCTCCGGA
GTATAACGGCTTCAAGATCAAGGAGGCTTTTGGCGGCTCCGCCCTCCCTTCCACCACCAGTGCCCTGGAGGAGATCGTGG
CCGCCAATGTGGCGACTGGCCGCCCCATCCAGGAGCGCCCCTTCGATGATGCCCTGAGGGAGGGGATGATCGAGTATTTC
GATCCTTGCCAGGGCTACTTTGAGCAGATCAGGCGCTATGTTGACCTGGATCTGATTGCCGAATCCGGTATCGCGGCGGT
GGTGGACCCCATGTACGGTGCCGGATGCGGCGCCATCCCACGCCTGCTGGCAGGGGTGGACGAGATCCACTGCGTTGAGA
ACCCCTGCTTTGGGGGCCAGCCCCCCGAGCCGATCGGGGAACATCTGGCCGAGCTTTCCGCTCTGGTGGCCGGCGGCACA
TACCGGGTTGGGCTTGCCCTGGACGGTGATGCCGACCGTATCGGGGCGATTGACGAGAACGGTGACTTCTTCTCCTCCCA
CTGCATCTTCACCGTCATACTGCGTCATCTGATCGAGCACAAGAAGTTGCGTGGCGGGGTGGTCAAAACCGTTTCCTCCA
CCCGCATGGTAGATCTGCTGGCAGCCAGGTACGGGCTGCGGCTCTTCGAGACCCCCATTGGCTTCAAGCATATCTGTGAA
TTGATGCTGAAGGAGGACATCCTGATGGGGGGCGAGGAATCGGGAGGGCTGGGGGTGAAGGGGCACATCCCCGAACGGGA
TGGCATCCTTATGGCACTCTTATTGCTTGAAGTCATGGCGGTTAACGGCAAGGGACTGCGGCAGCTGCTGAATGAGACCA
TGGACGAGATCGGCCATTTTTTCTATCGGCGCATAGATCACCGCATTGCGGAAGATGCCAAGGAACGGCTGGTTGCAAGG
CTCAGGACAGAGCCGCCAGCAGAGATTGCCAGCAGGATGGTCGTTGCCACCAACTTCAGTGACGGCTTCAAGTTCTTCTT
CGAAAACGGCGACTGGCTCCTGATCCGGCCGTCAGGCACCGAGCCGGTCTTGCGACTCTACAGCGAGGCCACCTCCCCCG
ATCGGGTCGACCAACTTCTGAGGGAGGCGGAACTCCTCGCCGGCGTGGCACCAGGCTGTCAGCCGGCTTCTCTGTAA

Upstream 100 bases:

>100_bases
GCGTACAGGCAGTACGTTGAGGAGCCTTGAACGAGCCAACGAAGAGAGCGCTTTGAGTTGGGATTGGAATGACACCATAC
CGTTACCTGTTGGAGGATCG

Downstream 100 bases:

>100_bases
CAACGTTCGGACCAGAAAAAAAATGATGAATTTTATGGATACTATGGTATTACTCATCGAACAAATAGACCCTGCCGCAC
GAGCGGGAAACCGAAAGAGG

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MRIKFGTDGWRGVIARDFTFDNLSLVAQATMDYLIQTNAAGRGLVVGYDRRFLSREFARRVAEIAAGNAIRVRLSDGYAP
TPAISWAVRESGAGAGIMVTASHNPPEYNGFKIKEAFGGSALPSTTSALEEIVAANVATGRPIQERPFDDALREGMIEYF
DPCQGYFEQIRRYVDLDLIAESGIAAVVDPMYGAGCGAIPRLLAGVDEIHCVENPCFGGQPPEPIGEHLAELSALVAGGT
YRVGLALDGDADRIGAIDENGDFFSSHCIFTVILRHLIEHKKLRGGVVKTVSSTRMVDLLAARYGLRLFETPIGFKHICE
LMLKEDILMGGEESGGLGVKGHIPERDGILMALLLLEVMAVNGKGLRQLLNETMDEIGHFFYRRIDHRIAEDAKERLVAR
LRTEPPAEIASRMVVATNFSDGFKFFFENGDWLLIRPSGTEPVLRLYSEATSPDRVDQLLREAELLAGVAPGCQPASL

Sequences:

>Translated_478_residues
MRIKFGTDGWRGVIARDFTFDNLSLVAQATMDYLIQTNAAGRGLVVGYDRRFLSREFARRVAEIAAGNAIRVRLSDGYAP
TPAISWAVRESGAGAGIMVTASHNPPEYNGFKIKEAFGGSALPSTTSALEEIVAANVATGRPIQERPFDDALREGMIEYF
DPCQGYFEQIRRYVDLDLIAESGIAAVVDPMYGAGCGAIPRLLAGVDEIHCVENPCFGGQPPEPIGEHLAELSALVAGGT
YRVGLALDGDADRIGAIDENGDFFSSHCIFTVILRHLIEHKKLRGGVVKTVSSTRMVDLLAARYGLRLFETPIGFKHICE
LMLKEDILMGGEESGGLGVKGHIPERDGILMALLLLEVMAVNGKGLRQLLNETMDEIGHFFYRRIDHRIAEDAKERLVAR
LRTEPPAEIASRMVVATNFSDGFKFFFENGDWLLIRPSGTEPVLRLYSEATSPDRVDQLLREAELLAGVAPGCQPASL
>Mature_478_residues
MRIKFGTDGWRGVIARDFTFDNLSLVAQATMDYLIQTNAAGRGLVVGYDRRFLSREFARRVAEIAAGNAIRVRLSDGYAP
TPAISWAVRESGAGAGIMVTASHNPPEYNGFKIKEAFGGSALPSTTSALEEIVAANVATGRPIQERPFDDALREGMIEYF
DPCQGYFEQIRRYVDLDLIAESGIAAVVDPMYGAGCGAIPRLLAGVDEIHCVENPCFGGQPPEPIGEHLAELSALVAGGT
YRVGLALDGDADRIGAIDENGDFFSSHCIFTVILRHLIEHKKLRGGVVKTVSSTRMVDLLAARYGLRLFETPIGFKHICE
LMLKEDILMGGEESGGLGVKGHIPERDGILMALLLLEVMAVNGKGLRQLLNETMDEIGHFFYRRIDHRIAEDAKERLVAR
LRTEPPAEIASRMVVATNFSDGFKFFFENGDWLLIRPSGTEPVLRLYSEATSPDRVDQLLREAELLAGVAPGCQPASL

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=472, Percent_Identity=25.8474576271186, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI290463102, Length=475, Percent_Identity=25.0526315789474, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI133922562, Length=491, Percent_Identity=24.6435845213849, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI31377548, Length=561, Percent_Identity=26.2032085561497, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI63055049, Length=548, Percent_Identity=24.0875912408759, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI290463104, Length=307, Percent_Identity=24.1042345276873, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI1786904, Length=487, Percent_Identity=28.5420944558522, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789566, Length=472, Percent_Identity=26.4830508474576, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788361, Length=423, Percent_Identity=26.9503546099291, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17535441, Length=528, Percent_Identity=27.6515151515151, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71993870, Length=530, Percent_Identity=25.6603773584906, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71993878, Length=149, Percent_Identity=35.5704697986577, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322722, Length=508, Percent_Identity=27.1653543307087, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6323752, Length=505, Percent_Identity=26.7326732673267, Blast_Score=112, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6323934, Length=414, Percent_Identity=26.3285024154589, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17864244, Length=516, Percent_Identity=28.4883720930233, Blast_Score=141, Evalue=8e-34,
Organism=Drosophila melanogaster, GI20129809, Length=531, Percent_Identity=25.4237288135593, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24651977, Length=449, Percent_Identity=25.6124721603563, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24653722, Length=144, Percent_Identity=34.0277777777778, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 52186; Mature: 52186

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIKFGTDGWRGVIARDFTFDNLSLVAQATMDYLIQTNAAGRGLVVGYDRRFLSREFARR
CEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHH
VAEIAAGNAIRVRLSDGYAPTPAISWAVRESGAGAGIMVTASHNPPEYNGFKIKEAFGGS
HHHHHCCCEEEEEECCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEECCCCCC
ALPSTTSALEEIVAANVATGRPIQERPFDDALREGMIEYFDPCQGYFEQIRRYVDLDLIA
CCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESGIAAVVDPMYGAGCGAIPRLLAGVDEIHCVENPCFGGQPPEPIGEHLAELSALVAGGT
CCCCHHHHCCCCCCCCCHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
YRVGLALDGDADRIGAIDENGDFFSSHCIFTVILRHLIEHKKLRGGVVKTVSSTRMVDLL
EEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AARYGLRLFETPIGFKHICELMLKEDILMGGEESGGLGVKGHIPERDGILMALLLLEVMA
HHHHCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
VNGKGLRQLLNETMDEIGHFFYRRIDHRIAEDAKERLVARLRTEPPAEIASRMVVATNFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEEECCC
DGFKFFFENGDWLLIRPSGTEPVLRLYSEATSPDRVDQLLREAELLAGVAPGCQPASL
CCCEEEEECCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRIKFGTDGWRGVIARDFTFDNLSLVAQATMDYLIQTNAAGRGLVVGYDRRFLSREFARR
CEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHH
VAEIAAGNAIRVRLSDGYAPTPAISWAVRESGAGAGIMVTASHNPPEYNGFKIKEAFGGS
HHHHHCCCEEEEEECCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEECCCCCC
ALPSTTSALEEIVAANVATGRPIQERPFDDALREGMIEYFDPCQGYFEQIRRYVDLDLIA
CCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESGIAAVVDPMYGAGCGAIPRLLAGVDEIHCVENPCFGGQPPEPIGEHLAELSALVAGGT
CCCCHHHHCCCCCCCCCHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
YRVGLALDGDADRIGAIDENGDFFSSHCIFTVILRHLIEHKKLRGGVVKTVSSTRMVDLL
EEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AARYGLRLFETPIGFKHICELMLKEDILMGGEESGGLGVKGHIPERDGILMALLLLEVMA
HHHHCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
VNGKGLRQLLNETMDEIGHFFYRRIDHRIAEDAKERLVARLRTEPPAEIASRMVVATNFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEEECCC
DGFKFFFENGDWLLIRPSGTEPVLRLYSEATSPDRVDQLLREAELLAGVAPGCQPASL
CCCEEEEECCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025683 [H]