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The map label for this gene is mtaD [H]

Identifier: 118581809

GI number: 118581809

Start: 3763808

End: 3765094

Strand: Direct

Name: mtaD [H]

Synonym: Ppro_3409

Alternate gene names: 118581809

Gene position: 3763808-3765094 (Clockwise)

Preceding gene: 118581807

Following gene: 118581814

Centisome position: 93.91

GC content: 68.22

Gene sequence:

>1287_bases
ATGACATCCTTCCCCATGGATAACGACTCCTTCATCGTGGCAGCCTCGTGGCTGCTCTCTCCCGAAGCGCCTCCCCTGGC
CGGTGGCGCGCTGCTGGTGCGTCGCGGCCGTATCGGGGACCTGGGCACCCTGCAGCGGTTGCGGCGCGATCACCCCGTTC
CGATCATCGACCATCCCGGCTGCGCCATCCTGCCCGGCTTCATCAATGCCCACACCCACCTGGAGTTGACCCATTTCCCC
AGCTGGCGCTTGCGCAGCCAGCTGGAGGAGCACCCGCAGCGCTTCGTGGACTGGATCATCCAGCTGATCAAGGTCAAGCG
CGGCCTGACCCCCGACGACATGCGTGCCTCGGCCCGGGAGGGGATCCGCATGTGCCTGGAGTCAGGAACCACCGCGGTGG
GGGAGATCGTCACGGCTCGCACGCTGGCGCCGCTGTACCGCGGATCCCGGCTCTCCGGCCGGCTGTTCTTCGAACTGGTG
GGACACGACAACTCCCGCTTCCGGGAATTGCTTCGGGAGGCGGTGGAGCTTAGCGGGGAATCTCCGGCCGGGTCGTTCAG
CGCGGGGCTCTCGCCCCATGCCCCCTACACCCTGGGGGAGGAGACCTTTCCGCTGATCCGGGAGGCGGCTGCGGGCGCAT
CCCTGCCGCTGGCCATCCACTGCTCCGAATCAACGGAGGAGACCAATTTCGTCTTCAGCAGCAGCGGCCAACTGGCCGAG
AGATTCTACCCCTTCGTGGGGTGGGAGCGCTACCTGCCCCCGCCACGCAGATGCAGCACCAGCCAGCTTCTGGAGCGGGC
CGGCCTGCTGACCGATTCCACCCTGGCCATCCACTGCGTACAGGTCAGCCGCGCGGATGCCGAGATCCTGAGGAAGCGCG
GCGTCAGCGTGGCCCTCTGCCCGCGCAGCAACGAGCGCCTGGACGTGGGGCGGGCACCGGTGGCGCTGCTGCGCAAGCTG
GGGATTCCCCTTGCCCTGGGCACCGACTCCCTGGCCAGCAACGACTCCCTCTCCCTCTGGGACGAGCTGCGCTTCGCCCT
GGATGCCTTCGGGGACGAGCTGTCGCCGGCCGACCTCTTCCGCATGGTCACCCTGGGGGGCGCCACCGCCCTGGGGATCC
AGGGGGACCACGGCTCTCTGGAGAAAGGGAAGCGGGCCGACTTCCAGATTGTGGGGCAGGCGGGAAAACGGGAGAGCGGG
CTTGTGGAGCGGGTCATGCTGCGGGGAGTCGTGGAGGATGTGTATGTGGCCGGAGAGCGGTTCGACGGGGAGCGGACATC
GCCCTGA

Upstream 100 bases:

>100_bases
TGCGTTAAGTCCGACAGACTCCTAGTGGCCGGTTCCTGCCGCGCTTCCAGGCTATGCCCCGGCCCATTCCATCCGCCGCC
ATGGCATCTGCGAGGAAACA

Downstream 100 bases:

>100_bases
GACAACGGTCGCCAGCCCCGCCAACGAGCCTTCCGCCGCGTCCTGCTACGGCTGTTCCTTCTCCGCTTCCTTCCCGGCCA
TGGCCGGCAGGTAGAGGCTG

Product: amidohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTSFPMDNDSFIVAASWLLSPEAPPLAGGALLVRRGRIGDLGTLQRLRRDHPVPIIDHPGCAILPGFINAHTHLELTHFP
SWRLRSQLEEHPQRFVDWIIQLIKVKRGLTPDDMRASAREGIRMCLESGTTAVGEIVTARTLAPLYRGSRLSGRLFFELV
GHDNSRFRELLREAVELSGESPAGSFSAGLSPHAPYTLGEETFPLIREAAAGASLPLAIHCSESTEETNFVFSSSGQLAE
RFYPFVGWERYLPPPRRCSTSQLLERAGLLTDSTLAIHCVQVSRADAEILRKRGVSVALCPRSNERLDVGRAPVALLRKL
GIPLALGTDSLASNDSLSLWDELRFALDAFGDELSPADLFRMVTLGGATALGIQGDHGSLEKGKRADFQIVGQAGKRESG
LVERVMLRGVVEDVYVAGERFDGERTSP

Sequences:

>Translated_428_residues
MTSFPMDNDSFIVAASWLLSPEAPPLAGGALLVRRGRIGDLGTLQRLRRDHPVPIIDHPGCAILPGFINAHTHLELTHFP
SWRLRSQLEEHPQRFVDWIIQLIKVKRGLTPDDMRASAREGIRMCLESGTTAVGEIVTARTLAPLYRGSRLSGRLFFELV
GHDNSRFRELLREAVELSGESPAGSFSAGLSPHAPYTLGEETFPLIREAAAGASLPLAIHCSESTEETNFVFSSSGQLAE
RFYPFVGWERYLPPPRRCSTSQLLERAGLLTDSTLAIHCVQVSRADAEILRKRGVSVALCPRSNERLDVGRAPVALLRKL
GIPLALGTDSLASNDSLSLWDELRFALDAFGDELSPADLFRMVTLGGATALGIQGDHGSLEKGKRADFQIVGQAGKRESG
LVERVMLRGVVEDVYVAGERFDGERTSP
>Mature_427_residues
TSFPMDNDSFIVAASWLLSPEAPPLAGGALLVRRGRIGDLGTLQRLRRDHPVPIIDHPGCAILPGFINAHTHLELTHFPS
WRLRSQLEEHPQRFVDWIIQLIKVKRGLTPDDMRASAREGIRMCLESGTTAVGEIVTARTLAPLYRGSRLSGRLFFELVG
HDNSRFRELLREAVELSGESPAGSFSAGLSPHAPYTLGEETFPLIREAAAGASLPLAIHCSESTEETNFVFSSSGQLAER
FYPFVGWERYLPPPRRCSTSQLLERAGLLTDSTLAIHCVQVSRADAEILRKRGVSVALCPRSNERLDVGRAPVALLRKLG
IPLALGTDSLASNDSLSLWDELRFALDAFGDELSPADLFRMVTLGGATALGIQGDHGSLEKGKRADFQIVGQAGKRESGL
VERVMLRGVVEDVYVAGERFDGERTSP

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=197, Percent_Identity=27.9187817258883, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319963, Length=354, Percent_Identity=22.5988700564972, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 46809; Mature: 46678

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSFPMDNDSFIVAASWLLSPEAPPLAGGALLVRRGRIGDLGTLQRLRRDHPVPIIDHPG
CCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEECCCC
CAILPGFINAHTHLELTHFPSWRLRSQLEEHPQRFVDWIIQLIKVKRGLTPDDMRASARE
CEEECHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GIRMCLESGTTAVGEIVTARTLAPLYRGSRLSGRLFFELVGHDNSRFRELLREAVELSGE
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCC
SPAGSFSAGLSPHAPYTLGEETFPLIREAAAGASLPLAIHCSESTEETNFVFSSSGQLAE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECCCHHHH
RFYPFVGWERYLPPPRRCSTSQLLERAGLLTDSTLAIHCVQVSRADAEILRKRGVSVALC
HHCCCCCHHHCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHCCCEEEEC
PRSNERLDVGRAPVALLRKLGIPLALGTDSLASNDSLSLWDELRFALDAFGDELSPADLF
CCCCCCCCCCCHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
RMVTLGGATALGIQGDHGSLEKGKRADFQIVGQAGKRESGLVERVMLRGVVEDVYVAGER
HHHHHCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCC
FDGERTSP
CCCCCCCC
>Mature Secondary Structure 
TSFPMDNDSFIVAASWLLSPEAPPLAGGALLVRRGRIGDLGTLQRLRRDHPVPIIDHPG
CCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEECCCC
CAILPGFINAHTHLELTHFPSWRLRSQLEEHPQRFVDWIIQLIKVKRGLTPDDMRASARE
CEEECHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GIRMCLESGTTAVGEIVTARTLAPLYRGSRLSGRLFFELVGHDNSRFRELLREAVELSGE
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCC
SPAGSFSAGLSPHAPYTLGEETFPLIREAAAGASLPLAIHCSESTEETNFVFSSSGQLAE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECCCHHHH
RFYPFVGWERYLPPPRRCSTSQLLERAGLLTDSTLAIHCVQVSRADAEILRKRGVSVALC
HHCCCCCHHHCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHCCCEEEEC
PRSNERLDVGRAPVALLRKLGIPLALGTDSLASNDSLSLWDELRFALDAFGDELSPADLF
CCCCCCCCCCCHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
RMVTLGGATALGIQGDHGSLEKGKRADFQIVGQAGKRESGLVERVMLRGVVEDVYVAGER
HHHHHCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCC
FDGERTSP
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]