Click here to switch to the map view.

The map label for this gene is pdxA [H]

Identifier: 118581630

GI number: 118581630

Start: 3547459

End: 3548481

Strand: Reverse

Name: pdxA [H]

Synonym: Ppro_3229

Alternate gene names: 118581630

Gene position: 3548481-3547459 (Counterclockwise)

Preceding gene: 118581631

Following gene: 118581628

Centisome position: 88.53

GC content: 67.64

Gene sequence:

>1023_bases
ATGCCTGATTCCACGGCCAGGCCGTTGATCGGCATCACCATGGGCGATCCCTGCGGGGTCGGCCCGGAGATCATCGTGAC
CGCCCTGGCCGACCCCCAGGTCCGGGCGCACTGCGTGCCGCTGGTGATCGGCGATCCGGCGGCGCTGGAGCGTGCCGTTC
GTGTCTGTGGCTCGGCTCTGCCAATCCGGGTGGTCGAATCGGTGGAGGAGGCGCGTCGGGTTGAAAACGGTGCTATCCCC
CTGCTGACCCTGTCCCGCTTGACGGAAGATGAGCTGCGCTATGGCCATCCTGGCCTGGCAGCCGGAACCGCGGTATACGA
CTACATCCGCTGCGCCACCGAGCTCTGTCTCCAGGGCAGGCTGGCGGCCATGGTCACGGCGCCTATCAGCAAGGAGGCCA
TGAACCGGGCCGGCCACCATTATCCGGGGCATACGGAACTTCTGGCCGAACTGTGCGGCACCGACAGCTACGTGATGATG
CTGGCCGGCGATCAGCTGCGGGTCAGCCTGGTGACGATCCACGAGGCGCTGCGCCATGTCCCCTCCCTGATAAGCCGGGA
GCGGGTGCTGACCACCATCCGGGTGACCCATGAAGGGGTTCGGCTCCTGACCGGAAAGGAACGCCCGCGCCTGGCGGTGC
TGGCCCTCAATCCCCACTGCGGCGAGGGGGGCATGTTCGGCGACGAGGAGGCGAGCGTCATCGCCCCTGCCATCCGGGCG
GCGCGGGACGAGGGGATCGACGCCCGGGGGCCGCTTTCCGCCGACACCCTCTTCCACTTCGCCCGCCAGGGGGAGTACGA
CGGGGTGGTGGCCATGTACCACGACCAGGGGCTGATACCGCTGAAACTGCTGCACTTCGACGACGGGGTCAACATCACCC
TGGGGCTGCCGATTATCCGCACCTCGGTGGACCATGGCACGGCCTACGACCTGGCGGGAACCGGCAGGGCGTCCAGTCGC
AGCATGCTGGCCGCCATAGCCATGGCGGTGGACATGGCGACTTCGAGCCCGGGATCTGAATGA

Upstream 100 bases:

>100_bases
CCGGCTGCGCTCCTGGCTTCGGGCGGGGGGCGCCTGCTGTTGCAGAAGGTCAAATCCCCCAACGTCACCCTGGCGGTGGC
GGAGATTCCCGGAGGAGAGC

Downstream 100 bases:

>100_bases
GTTGTCGGTCACACGGTATGCATGTCACTATTGAAACGCTCCTCTCGTTGGCATCGCCCCTGGATCTCCTGCACGCTCAT
CGTACGCCGTCCCTTCCCTC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MPDSTARPLIGITMGDPCGVGPEIIVTALADPQVRAHCVPLVIGDPAALERAVRVCGSALPIRVVESVEEARRVENGAIP
LLTLSRLTEDELRYGHPGLAAGTAVYDYIRCATELCLQGRLAAMVTAPISKEAMNRAGHHYPGHTELLAELCGTDSYVMM
LAGDQLRVSLVTIHEALRHVPSLISRERVLTTIRVTHEGVRLLTGKERPRLAVLALNPHCGEGGMFGDEEASVIAPAIRA
ARDEGIDARGPLSADTLFHFARQGEYDGVVAMYHDQGLIPLKLLHFDDGVNITLGLPIIRTSVDHGTAYDLAGTGRASSR
SMLAAIAMAVDMATSSPGSE

Sequences:

>Translated_340_residues
MPDSTARPLIGITMGDPCGVGPEIIVTALADPQVRAHCVPLVIGDPAALERAVRVCGSALPIRVVESVEEARRVENGAIP
LLTLSRLTEDELRYGHPGLAAGTAVYDYIRCATELCLQGRLAAMVTAPISKEAMNRAGHHYPGHTELLAELCGTDSYVMM
LAGDQLRVSLVTIHEALRHVPSLISRERVLTTIRVTHEGVRLLTGKERPRLAVLALNPHCGEGGMFGDEEASVIAPAIRA
ARDEGIDARGPLSADTLFHFARQGEYDGVVAMYHDQGLIPLKLLHFDDGVNITLGLPIIRTSVDHGTAYDLAGTGRASSR
SMLAAIAMAVDMATSSPGSE
>Mature_339_residues
PDSTARPLIGITMGDPCGVGPEIIVTALADPQVRAHCVPLVIGDPAALERAVRVCGSALPIRVVESVEEARRVENGAIPL
LTLSRLTEDELRYGHPGLAAGTAVYDYIRCATELCLQGRLAAMVTAPISKEAMNRAGHHYPGHTELLAELCGTDSYVMML
AGDQLRVSLVTIHEALRHVPSLISRERVLTTIRVTHEGVRLLTGKERPRLAVLALNPHCGEGGMFGDEEASVIAPAIRAA
RDEGIDARGPLSADTLFHFARQGEYDGVVAMYHDQGLIPLKLLHFDDGVNITLGLPIIRTSVDHGTAYDLAGTGRASSRS
MLAAIAMAVDMATSSPGSE

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=326, Percent_Identity=39.2638036809816, Blast_Score=202, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 36199; Mature: 36068

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDSTARPLIGITMGDPCGVGPEIIVTALADPQVRAHCVPLVIGDPAALERAVRVCGSAL
CCCCCCCCEEEEEECCCCCCCHHHEEEECCCCCCEEEEEEEEECCHHHHHHHHHHCCCCC
PIRVVESVEEARRVENGAIPLLTLSRLTEDELRYGHPGLAAGTAVYDYIRCATELCLQGR
HHHHHHHHHHHHHHHCCCCCEEEHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
LAAMVTAPISKEAMNRAGHHYPGHTELLAELCGTDSYVMMLAGDQLRVSLVTIHEALRHV
HHEEEECCCCHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCEEEHHHHHHHHHHHH
PSLISRERVLTTIRVTHEGVRLLTGKERPRLAVLALNPHCGEGGMFGDEEASVIAPAIRA
HHHHHHHHHHEEEEEECCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
ARDEGIDARGPLSADTLFHFARQGEYDGVVAMYHDQGLIPLKLLHFDDGVNITLGLPIIR
HHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEECCCCEEEECCCEEE
TSVDHGTAYDLAGTGRASSRSMLAAIAMAVDMATSSPGSE
ECCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PDSTARPLIGITMGDPCGVGPEIIVTALADPQVRAHCVPLVIGDPAALERAVRVCGSAL
CCCCCCCEEEEEECCCCCCCHHHEEEECCCCCCEEEEEEEEECCHHHHHHHHHHCCCCC
PIRVVESVEEARRVENGAIPLLTLSRLTEDELRYGHPGLAAGTAVYDYIRCATELCLQGR
HHHHHHHHHHHHHHHCCCCCEEEHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
LAAMVTAPISKEAMNRAGHHYPGHTELLAELCGTDSYVMMLAGDQLRVSLVTIHEALRHV
HHEEEECCCCHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCEEEHHHHHHHHHHHH
PSLISRERVLTTIRVTHEGVRLLTGKERPRLAVLALNPHCGEGGMFGDEEASVIAPAIRA
HHHHHHHHHHEEEEEECCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
ARDEGIDARGPLSADTLFHFARQGEYDGVVAMYHDQGLIPLKLLHFDDGVNITLGLPIIR
HHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEECCCCEEEECCCEEE
TSVDHGTAYDLAGTGRASSRSMLAAIAMAVDMATSSPGSE
ECCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA