| Definition | Pelobacter propionicus DSM 2379 chromosome, complete genome. |
|---|---|
| Accession | NC_008609 |
| Length | 4,008,000 |
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The map label for this gene is mrcA [H]
Identifier: 118581596
GI number: 118581596
Start: 3510494
End: 3512815
Strand: Reverse
Name: mrcA [H]
Synonym: Ppro_3195
Alternate gene names: 118581596
Gene position: 3512815-3510494 (Counterclockwise)
Preceding gene: 118581597
Following gene: 118581594
Centisome position: 87.65
GC content: 61.93
Gene sequence:
>2322_bases ATGGAGAGAAGAGCGCCGTCATCCGGCGGCGGGAAGGGCCTGCTCAAGGTGGTCCTGCTGTGTGTCGCCACCTTGGCCGT CATATCCGCCCTGGGGGCGGGCGGGTATCTGTTTTATCTGCTTTCCCGCCTTCCCAGGGTCGACCGCCTGGCCGACTATA AACCGCCCATCGTGTCACAGGTGTTCGGCGACGATGGCAGCCTGGTGGGTGAGTTCTATCTGGAACGGCGCATCGTAGTC CCGGTGGACCGGATGCCGCGCAAGCTGATCCAGGCCTTTGTGGCCGCCGAAGATGCCAGCTTCTATTCCCACCGGGGGAT CGATTACTTCGGCATCCTGCGCGCCGCGTTCAAGAACGTCCTCTCCATGCGTAAAAAGGAGGGCGCCTCCACCATCACCC AGCAGGTGACCAAGTCCATGCTGCTGACCTCCGAGAAGAAGTTCTCCCGCAAGATCAAGGAAGCCATCCTGGCCAAGCGC ATGGAGGAGAAGCTCACCAAGGACGAAATCCTCTATATTTACCTCAATCAGATCTATATGGGTGCGGGGGCCTATGGCGT GCAGGCCGCGGCCGAGACCTATTTCGGAAAAGATGTTGATCATCTCAACCTGGCCGAGATGGCCATGCTGGCCGGTCTGC CCAAGTCGCCCAACGCCTATTCGCCCATCAAGCATCTGGAAAAAGCCCGGGAACGCCAAGCCTACGTCCTGGACCGGATG GTCAAAGAGGCCTACATCACGCCAGCCGAGGCGGAACATGCCCGGAACACCCCGCTCTCCATCCATCCCATGAAGAAGGT CAACAATGAACAGTCGGCCTACTTCCTGGAATACCTGCGTATCCAGCTGGAGGAACGCTATGGCGAGGACCAGCTCTACA AGGGGGGGCTGAAAATCTACACCACCATGAATGCTGCCATGCAGCGTGCCGCCTACGAGAGCCTGCGGGCCGGCCTCAAG GCGGTGGACAAACGCCAGGGGTTCCGCGGGCCGCAGAAGTATCTCCAGGCGGACGAGGTGGATGCTTTCTGCGCCAATGT GGAGGCGGGGATCGATTCGGCCGTGCTCAAGACCGGCGAGACCTACCAGGGGGTGGTGGTGGGCGTGAACCCGGCCAGGG GAGAGGCCAGGGTCAGGGTGGGGGAACGCACGGGGATTCTCAGTAGAAAGAACATGGCTTGGGCTGGCCGACTGGCTCTG GTCAACGGCTATGACCAGCCCCGCAAGGGGCGTAAATCCCTCTGTCTCGGTTCGGTGATCGATGTGGCGGTGGTTTCGCC GGAGATCGACAAGCAGGGTGCCCAGTTCAGCCTGGACCAGACTCCCGATGTGCAGGCGGCCCTGGTGGCCATTGATCCCC GCAGCGGCGGTATCAAGGCCATGGTCGGCGGCTATGACTTCAGGAAGAGCCAGTTCAACCGGGCCATGCAGTCCAGGCGT AATGCCGGTTCGGCCTTCAAGCCGATCATCTACGCTGCCGCCCTGGACAAGGGCTTTACGCCGGCCACGGTGATCGAGGA CGTGGAGGTTGAATATCCGGACGGTTCCGGTGGCATCTGGAAGCCGAAGAACTACGATGGCACCTTCAGGGGGCCGGTAA CCATGCGCGAGGCCCTGACCAATTCCATCAACATCGTCAGCGTCAAGATCATGGATCAGATCGGCGCCTCCTATGCCGCC GACTATGCCAGGAAGTTCGGTTTTACCAGCCCCATTTCCGCTAACCTGGCCCTGGCACTGGGAGCAGCCTCGGTCTCTCC CCTGGAGTTGACATCCGCCTACGCTGTCTTTGCCAACAAGGGGGTCTCCCTGCCCAGGTCGGTGATCACCAAGGTGACGG ACAATGACGGCGTGGTGCTCCAGCAGCAGGATTCGGTTCCGGTGGCGACTCCGATCCTGTCACCCGAGAACGCCTACGTT ATCACCAACCTGATGCAGAGCGTGGTGTCCAGCGGGACCGGGCACCGCGCGTCCATCGTCGGCCGGCCGGTGGCCGGTAA AACCGGCACCACCAATGACTCCAAGGATGCCTGGTTCGTCGGCTATGTCCCCCAACTGGCGGCCGGGGTCTGGGTTGGCT ATGACCAGGAGCGCTCCCTGGGGGCGGGAGGGTCGGGCGGTCAGGCAGCCGCCCCCATCTGGGCGGAATTCATGCAGAAG GCGGTGTCCGAGTTGCCAGTGGAGGATTTTGAGGCTCCGGAGAATGTCACCTTCGTGCTGATAAACCCGCGCACCGGCAG GCTTGCCCGGGAGGGAACGCCGGGCGCCATCATGGAGTGCTTCGTCAAGGGCGCCGAACCGTCCAGCTATGACGGTGACT GA
Upstream 100 bases:
>100_bases TTCGTCCGCCGGTCTGCGCTATTTTTCCCGGGCAACGAGTGCCGGAAGGTTCCCATGCAGGCACTGAAACAGTGCCGCGG GAACACGAGAGGATATGAAC
Downstream 100 bases:
>100_bases GGCTCCGCGTCCCCTCTGTCTGGATCCGGAGTAAGAAAGCAAAACGGGCGCCCACGAAAGGGCGCCCGTTTCTGTTCGTG GCATACCGGTCGGTGCGCGG
Product: 1A family penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 773; Mature: 773
Protein sequence:
>773_residues MERRAPSSGGGKGLLKVVLLCVATLAVISALGAGGYLFYLLSRLPRVDRLADYKPPIVSQVFGDDGSLVGEFYLERRIVV PVDRMPRKLIQAFVAAEDASFYSHRGIDYFGILRAAFKNVLSMRKKEGASTITQQVTKSMLLTSEKKFSRKIKEAILAKR MEEKLTKDEILYIYLNQIYMGAGAYGVQAAAETYFGKDVDHLNLAEMAMLAGLPKSPNAYSPIKHLEKARERQAYVLDRM VKEAYITPAEAEHARNTPLSIHPMKKVNNEQSAYFLEYLRIQLEERYGEDQLYKGGLKIYTTMNAAMQRAAYESLRAGLK AVDKRQGFRGPQKYLQADEVDAFCANVEAGIDSAVLKTGETYQGVVVGVNPARGEARVRVGERTGILSRKNMAWAGRLAL VNGYDQPRKGRKSLCLGSVIDVAVVSPEIDKQGAQFSLDQTPDVQAALVAIDPRSGGIKAMVGGYDFRKSQFNRAMQSRR NAGSAFKPIIYAAALDKGFTPATVIEDVEVEYPDGSGGIWKPKNYDGTFRGPVTMREALTNSINIVSVKIMDQIGASYAA DYARKFGFTSPISANLALALGAASVSPLELTSAYAVFANKGVSLPRSVITKVTDNDGVVLQQQDSVPVATPILSPENAYV ITNLMQSVVSSGTGHRASIVGRPVAGKTGTTNDSKDAWFVGYVPQLAAGVWVGYDQERSLGAGGSGGQAAAPIWAEFMQK AVSELPVEDFEAPENVTFVLINPRTGRLAREGTPGAIMECFVKGAEPSSYDGD
Sequences:
>Translated_773_residues MERRAPSSGGGKGLLKVVLLCVATLAVISALGAGGYLFYLLSRLPRVDRLADYKPPIVSQVFGDDGSLVGEFYLERRIVV PVDRMPRKLIQAFVAAEDASFYSHRGIDYFGILRAAFKNVLSMRKKEGASTITQQVTKSMLLTSEKKFSRKIKEAILAKR MEEKLTKDEILYIYLNQIYMGAGAYGVQAAAETYFGKDVDHLNLAEMAMLAGLPKSPNAYSPIKHLEKARERQAYVLDRM VKEAYITPAEAEHARNTPLSIHPMKKVNNEQSAYFLEYLRIQLEERYGEDQLYKGGLKIYTTMNAAMQRAAYESLRAGLK AVDKRQGFRGPQKYLQADEVDAFCANVEAGIDSAVLKTGETYQGVVVGVNPARGEARVRVGERTGILSRKNMAWAGRLAL VNGYDQPRKGRKSLCLGSVIDVAVVSPEIDKQGAQFSLDQTPDVQAALVAIDPRSGGIKAMVGGYDFRKSQFNRAMQSRR NAGSAFKPIIYAAALDKGFTPATVIEDVEVEYPDGSGGIWKPKNYDGTFRGPVTMREALTNSINIVSVKIMDQIGASYAA DYARKFGFTSPISANLALALGAASVSPLELTSAYAVFANKGVSLPRSVITKVTDNDGVVLQQQDSVPVATPILSPENAYV ITNLMQSVVSSGTGHRASIVGRPVAGKTGTTNDSKDAWFVGYVPQLAAGVWVGYDQERSLGAGGSGGQAAAPIWAEFMQK AVSELPVEDFEAPENVTFVLINPRTGRLAREGTPGAIMECFVKGAEPSSYDGD >Mature_773_residues MERRAPSSGGGKGLLKVVLLCVATLAVISALGAGGYLFYLLSRLPRVDRLADYKPPIVSQVFGDDGSLVGEFYLERRIVV PVDRMPRKLIQAFVAAEDASFYSHRGIDYFGILRAAFKNVLSMRKKEGASTITQQVTKSMLLTSEKKFSRKIKEAILAKR MEEKLTKDEILYIYLNQIYMGAGAYGVQAAAETYFGKDVDHLNLAEMAMLAGLPKSPNAYSPIKHLEKARERQAYVLDRM VKEAYITPAEAEHARNTPLSIHPMKKVNNEQSAYFLEYLRIQLEERYGEDQLYKGGLKIYTTMNAAMQRAAYESLRAGLK AVDKRQGFRGPQKYLQADEVDAFCANVEAGIDSAVLKTGETYQGVVVGVNPARGEARVRVGERTGILSRKNMAWAGRLAL VNGYDQPRKGRKSLCLGSVIDVAVVSPEIDKQGAQFSLDQTPDVQAALVAIDPRSGGIKAMVGGYDFRKSQFNRAMQSRR NAGSAFKPIIYAAALDKGFTPATVIEDVEVEYPDGSGGIWKPKNYDGTFRGPVTMREALTNSINIVSVKIMDQIGASYAA DYARKFGFTSPISANLALALGAASVSPLELTSAYAVFANKGVSLPRSVITKVTDNDGVVLQQQDSVPVATPILSPENAYV ITNLMQSVVSSGTGHRASIVGRPVAGKTGTTNDSKDAWFVGYVPQLAAGVWVGYDQERSLGAGGSGGQAAAPIWAEFMQK AVSELPVEDFEAPENVTFVLINPRTGRLAREGTPGAIMECFVKGAEPSSYDGD
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=837, Percent_Identity=35.2449223416965, Blast_Score=453, Evalue=1e-128, Organism=Escherichia coli, GI1786343, Length=281, Percent_Identity=32.0284697508897, Blast_Score=141, Evalue=1e-34, Organism=Escherichia coli, GI1788867, Length=257, Percent_Identity=31.5175097276265, Blast_Score=112, Evalue=7e-26, Organism=Escherichia coli, GI1789601, Length=174, Percent_Identity=35.0574712643678, Blast_Score=91, Evalue=4e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 83920; Mature: 83920
Theoretical pI: Translated: 9.34; Mature: 9.34
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MERRAPSSGGGKGLLKVVLLCVATLAVISALGAGGYLFYLLSRLPRVDRLADYKPPIVSQ CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCCHHHH VFGDDGSLVGEFYLERRIVVPVDRMPRKLIQAFVAAEDASFYSHRGIDYFGILRAAFKNV HHCCCCCHHHHHHHCCEEEECHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHH LSMRKKEGASTITQQVTKSMLLTSEKKFSRKIKEAILAKRMEEKLTKDEILYIYLNQIYM HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHH GAGAYGVQAAAETYFGKDVDHLNLAEMAMLAGLPKSPNAYSPIKHLEKARERQAYVLDRM CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH VKEAYITPAEAEHARNTPLSIHPMKKVNNEQSAYFLEYLRIQLEERYGEDQLYKGGLKIY HHHHCCCCCHHHHCCCCCCEECCHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCEEEE TTMNAAMQRAAYESLRAGLKAVDKRQGFRGPQKYLQADEVDAFCANVEAGIDSAVLKTGE EHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC TYQGVVVGVNPARGEARVRVGERTGILSRKNMAWAGRLALVNGYDQPRKGRKSLCLGSVI CCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH DVAVVSPEIDKQGAQFSLDQTPDVQAALVAIDPRSGGIKAMVGGYDFRKSQFNRAMQSRR HHHEECCCCCCCCCCEECCCCCCCEEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHH NAGSAFKPIIYAAALDKGFTPATVIEDVEVEYPDGSGGIWKPKNYDGTFRGPVTMREALT CCCCHHHHHHHHHHHCCCCCCHHEEECCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHC NSINIVSVKIMDQIGASYAADYARKFGFTSPISANLALALGAASVSPLELTSAYAVFANK CCCEEEEEEEHHHHCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCC GVSLPRSVITKVTDNDGVVLQQQDSVPVATPILSPENAYVITNLMQSVVSSGTGHRASIV CCCCCHHHHHHCCCCCCEEEEECCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEE GRPVAGKTGTTNDSKDAWFVGYVPQLAAGVWVGYDQERSLGAGGSGGQAAAPIWAEFMQK CCCCCCCCCCCCCCCCCEEEECHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHH AVSELPVEDFEAPENVTFVLINPRTGRLAREGTPGAIMECFVKGAEPSSYDGD HHHHCCCHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC >Mature Secondary Structure MERRAPSSGGGKGLLKVVLLCVATLAVISALGAGGYLFYLLSRLPRVDRLADYKPPIVSQ CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCCHHHH VFGDDGSLVGEFYLERRIVVPVDRMPRKLIQAFVAAEDASFYSHRGIDYFGILRAAFKNV HHCCCCCHHHHHHHCCEEEECHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHH LSMRKKEGASTITQQVTKSMLLTSEKKFSRKIKEAILAKRMEEKLTKDEILYIYLNQIYM HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHH GAGAYGVQAAAETYFGKDVDHLNLAEMAMLAGLPKSPNAYSPIKHLEKARERQAYVLDRM CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH VKEAYITPAEAEHARNTPLSIHPMKKVNNEQSAYFLEYLRIQLEERYGEDQLYKGGLKIY HHHHCCCCCHHHHCCCCCCEECCHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCEEEE TTMNAAMQRAAYESLRAGLKAVDKRQGFRGPQKYLQADEVDAFCANVEAGIDSAVLKTGE EHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC TYQGVVVGVNPARGEARVRVGERTGILSRKNMAWAGRLALVNGYDQPRKGRKSLCLGSVI CCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH DVAVVSPEIDKQGAQFSLDQTPDVQAALVAIDPRSGGIKAMVGGYDFRKSQFNRAMQSRR HHHEECCCCCCCCCCEECCCCCCCEEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHH NAGSAFKPIIYAAALDKGFTPATVIEDVEVEYPDGSGGIWKPKNYDGTFRGPVTMREALT CCCCHHHHHHHHHHHCCCCCCHHEEECCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHC NSINIVSVKIMDQIGASYAADYARKFGFTSPISANLALALGAASVSPLELTSAYAVFANK CCCEEEEEEEHHHHCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCC GVSLPRSVITKVTDNDGVVLQQQDSVPVATPILSPENAYVITNLMQSVVSSGTGHRASIV CCCCCHHHHHHCCCCCCEEEEECCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEE GRPVAGKTGTTNDSKDAWFVGYVPQLAAGVWVGYDQERSLGAGGSGGQAAAPIWAEFMQK CCCCCCCCCCCCCCCCCEEEECHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHH AVSELPVEDFEAPENVTFVLINPRTGRLAREGTPGAIMECFVKGAEPSSYDGD HHHHCCCHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA