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The map label for this gene is yciR [C]

Identifier: 118581541

GI number: 118581541

Start: 3442649

End: 3444913

Strand: Direct

Name: yciR [C]

Synonym: Ppro_3140

Alternate gene names: 118581541

Gene position: 3442649-3444913 (Clockwise)

Preceding gene: 118581540

Following gene: 118581542

Centisome position: 85.89

GC content: 59.25

Gene sequence:

>2265_bases
GTGAACAGCCTGAACACGACAACCAGGGCTGCCCTTGAGCGTCACGACAGGCCGCACAGCATCCTGATTGTGGATGACGA
GCCGCGCATGCGCACAAGCCTGCGCATCCTGCTGCAGGAGAGCGGGCGCGAAATACTGGAGAGCAAAAGCGGGGGCGAGG
CGATCGCCACGCTGAAAACGAAGCAGATCGACCTGGTCCTGCTTGACATCATCCTCCCCGACATCTCCGGCCTGGATGTC
CTGGAGTGGATCACCAGCAGGGGAGACGCACTCCCGGCCAGCGTCATCATAGTCAGCGTCGATGACAACATCGACTCAGC
CATCCACGCCCTACGCAACGGTGCCTCTGAATATATCCGCAAACCGTACGAACCGGAGGTCATCCAGCACAAAGTCAGAA
ACATCCTCTACCGGCGCCACCTGGAACGCGACCATGTGCTGATAACTTCCCGCCTGCAACACTCGGAGCAGCTGCATCGC
TTCCTGGTGGAGAGCTCTCCCGACCTGATCTTCACCCTGGACAACTCCGGCTGTTTTACGTTCATCAACAGTCGCATCGA
ATCGCTGCTCGGCTTCTCGCGCGAGGAGTTGATCGGCAGCTGCTACGACACCATCGTCCTTGCCGAGGACTTAAAAACAG
CCCAGCACCCCTTTACCGAACGCCGCCGGGGCAACCGAGCCACCACCAACCTTGAGATACGGCTGAAGTGCACCCCCAGC
CATTACCGTAACTTTGAGAATCACCATATCGTGGTGATGATGAGCTCAACCGGCATCTACGGCGAGCACGACAACGACTT
CCCGCTTGCCCGCTGCTTCAGCGGCACCTATGGCGTGGCCCGCGACATCACCGACCGGAAAATCGCCGAGGAGACCATCG
CCTTCCAGGCCTTCCACGACCACCTCACCCACCTGCCCAACCAGCGACTCTTCAAGGACCGCCTGGAAATGGCCATAACC
CACTCCAAGCGCCATGGGGGAATGGTCGGAGTCATGTTCATCGATTTGGATCGTTTCAAGATCGTCAACGACACCCATGG
TCACGCCGCCGGCGACGAACTACTGAAGAACGTCGCCCACCGCCTGCGCCACTGCATCCGCGCCGTGGACACCCTGGCGC
GCAAGGGGGGAGACGAGTTCACCGTGCTGCTGCCGGATCTGATGCGCGCCGAGGACGCGGCCCTGATCGCCGAAAAAATC
ATGCACGAACTGGGTATCCCCTTTTCCGTTGCCGGACAGAAGTTTCACGTTTCCGCCAGCATCGGCATAGCCATCGTGCC
ACGGGACGGGGAGAGTATCGATACCCTTTTGAAGAGCGCCGACATCGCCATGTACCGGGTCAAGGCCAGCGGCAAGAACG
GCTACCGCTTCTTTACCCCGGACATGAACATCTGTTACACCAAACGCATCAGCCTGGAAAACGAACTGCGCCAGGCGATC
CCCAACTCGGAATTCGAACTATTCTACCAGCCCCAGGTCAGCATCAACGGAGCCTCCATCATCGGCCTTGAAGCGCTGAT
TCGTTGGCGTCACCCGACCCACGGCCTGTTGAATCCGGGAGATTTCATCGAACTGGCCGAGGAAACCGGCATGATCGGCA
CCATCACCGACTGGGTACTGGCCGAGGCCTGCAGACAGTTAGCCCACTGGCGTTCCATGGGGTTCAGCGACCTGCGCATT
GCCGTGAACGTATCCCCCAAGGAGTTCGAACGGGACGACATGGTGGAGCAGCTCTCAAGATTCATGTCCACCTTCCAACT
TCCACCGGACTCCCTGGAGGTGGAGATAACGGAAAAGATCCTCCTGCGCGACACCCCCAGCGTCATCAACAAGATGAAGA
CCCTGCGCGAACGGGGCATACGCATCTCCATCGACGATTTCGGCACCTGCTATTCGTCACTCAACTATCTGCGGCAGTTC
CCCATCAGCACCATCAAGATCGACCAGTCCTTTGTACGCGACCTGTCGGAAGAACACCGCATCTCACCGATCATACAGGC
CATCATCGGCATAGCCAATGGCTTCGGCCTGCACCTGCTGGCAGAAGGCGTGGAGACGCACTGCCAGATGCAGACCCTGC
ATGCACTGGGCTGCAACGAGATGCAGGGCTATCTGTTCAGCAGGCCGGCACCAGCCGAACAGATCGAGCAGATGCTGTGC
CACACGATCTCACACACCACATTGCAATCGCCGGACTTCCTCACCCATCCGCAACTGCTCTCCCCTCTGCTCACTCAGGG
CCTCCAGGAACGCCCCCTGGCTTGA

Upstream 100 bases:

>100_bases
GACTGGTTGAACGCATGCATGGCCGCATCACCTGCCAGAGCAGGAGGGGACAGGGAACCACATTTTCTATCCTGCTGCCG
CACTCCGGGAGGGACGAGTC

Downstream 100 bases:

>100_bases
ACGATCACAGGTACGCCCGCAACGCATCACAAACAGCGTTATCAAAACAAATTTCTGGCTCGCCGCTTCTCCCCGAGCCT
CGTCTCTTCCCTCCAGAAGC

Product: response regulator receiver modulated PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 754; Mature: 754

Protein sequence:

>754_residues
MNSLNTTTRAALERHDRPHSILIVDDEPRMRTSLRILLQESGREILESKSGGEAIATLKTKQIDLVLLDIILPDISGLDV
LEWITSRGDALPASVIIVSVDDNIDSAIHALRNGASEYIRKPYEPEVIQHKVRNILYRRHLERDHVLITSRLQHSEQLHR
FLVESSPDLIFTLDNSGCFTFINSRIESLLGFSREELIGSCYDTIVLAEDLKTAQHPFTERRRGNRATTNLEIRLKCTPS
HYRNFENHHIVVMMSSTGIYGEHDNDFPLARCFSGTYGVARDITDRKIAEETIAFQAFHDHLTHLPNQRLFKDRLEMAIT
HSKRHGGMVGVMFIDLDRFKIVNDTHGHAAGDELLKNVAHRLRHCIRAVDTLARKGGDEFTVLLPDLMRAEDAALIAEKI
MHELGIPFSVAGQKFHVSASIGIAIVPRDGESIDTLLKSADIAMYRVKASGKNGYRFFTPDMNICYTKRISLENELRQAI
PNSEFELFYQPQVSINGASIIGLEALIRWRHPTHGLLNPGDFIELAEETGMIGTITDWVLAEACRQLAHWRSMGFSDLRI
AVNVSPKEFERDDMVEQLSRFMSTFQLPPDSLEVEITEKILLRDTPSVINKMKTLRERGIRISIDDFGTCYSSLNYLRQF
PISTIKIDQSFVRDLSEEHRISPIIQAIIGIANGFGLHLLAEGVETHCQMQTLHALGCNEMQGYLFSRPAPAEQIEQMLC
HTISHTTLQSPDFLTHPQLLSPLLTQGLQERPLA

Sequences:

>Translated_754_residues
MNSLNTTTRAALERHDRPHSILIVDDEPRMRTSLRILLQESGREILESKSGGEAIATLKTKQIDLVLLDIILPDISGLDV
LEWITSRGDALPASVIIVSVDDNIDSAIHALRNGASEYIRKPYEPEVIQHKVRNILYRRHLERDHVLITSRLQHSEQLHR
FLVESSPDLIFTLDNSGCFTFINSRIESLLGFSREELIGSCYDTIVLAEDLKTAQHPFTERRRGNRATTNLEIRLKCTPS
HYRNFENHHIVVMMSSTGIYGEHDNDFPLARCFSGTYGVARDITDRKIAEETIAFQAFHDHLTHLPNQRLFKDRLEMAIT
HSKRHGGMVGVMFIDLDRFKIVNDTHGHAAGDELLKNVAHRLRHCIRAVDTLARKGGDEFTVLLPDLMRAEDAALIAEKI
MHELGIPFSVAGQKFHVSASIGIAIVPRDGESIDTLLKSADIAMYRVKASGKNGYRFFTPDMNICYTKRISLENELRQAI
PNSEFELFYQPQVSINGASIIGLEALIRWRHPTHGLLNPGDFIELAEETGMIGTITDWVLAEACRQLAHWRSMGFSDLRI
AVNVSPKEFERDDMVEQLSRFMSTFQLPPDSLEVEITEKILLRDTPSVINKMKTLRERGIRISIDDFGTCYSSLNYLRQF
PISTIKIDQSFVRDLSEEHRISPIIQAIIGIANGFGLHLLAEGVETHCQMQTLHALGCNEMQGYLFSRPAPAEQIEQMLC
HTISHTTLQSPDFLTHPQLLSPLLTQGLQERPLA
>Mature_754_residues
MNSLNTTTRAALERHDRPHSILIVDDEPRMRTSLRILLQESGREILESKSGGEAIATLKTKQIDLVLLDIILPDISGLDV
LEWITSRGDALPASVIIVSVDDNIDSAIHALRNGASEYIRKPYEPEVIQHKVRNILYRRHLERDHVLITSRLQHSEQLHR
FLVESSPDLIFTLDNSGCFTFINSRIESLLGFSREELIGSCYDTIVLAEDLKTAQHPFTERRRGNRATTNLEIRLKCTPS
HYRNFENHHIVVMMSSTGIYGEHDNDFPLARCFSGTYGVARDITDRKIAEETIAFQAFHDHLTHLPNQRLFKDRLEMAIT
HSKRHGGMVGVMFIDLDRFKIVNDTHGHAAGDELLKNVAHRLRHCIRAVDTLARKGGDEFTVLLPDLMRAEDAALIAEKI
MHELGIPFSVAGQKFHVSASIGIAIVPRDGESIDTLLKSADIAMYRVKASGKNGYRFFTPDMNICYTKRISLENELRQAI
PNSEFELFYQPQVSINGASIIGLEALIRWRHPTHGLLNPGDFIELAEETGMIGTITDWVLAEACRQLAHWRSMGFSDLRI
AVNVSPKEFERDDMVEQLSRFMSTFQLPPDSLEVEITEKILLRDTPSVINKMKTLRERGIRISIDDFGTCYSSLNYLRQF
PISTIKIDQSFVRDLSEEHRISPIIQAIIGIANGFGLHLLAEGVETHCQMQTLHALGCNEMQGYLFSRPAPAEQIEQMLC
HTISHTTLQSPDFLTHPQLLSPLLTQGLQERPLA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=574, Percent_Identity=32.7526132404181, Blast_Score=306, Evalue=4e-84,
Organism=Escherichia coli, GI87081921, Length=430, Percent_Identity=35.8139534883721, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI226510982, Length=445, Percent_Identity=26.9662921348315, Blast_Score=185, Evalue=1e-47,
Organism=Escherichia coli, GI1790496, Length=250, Percent_Identity=31.6, Blast_Score=144, Evalue=3e-35,
Organism=Escherichia coli, GI87081980, Length=252, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI1788502, Length=259, Percent_Identity=30.8880308880309, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI1788381, Length=583, Percent_Identity=25.7289879931389, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI87081845, Length=245, Percent_Identity=33.0612244897959, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI1786507, Length=269, Percent_Identity=30.1115241635688, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1787055, Length=246, Percent_Identity=33.3333333333333, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI87081743, Length=243, Percent_Identity=32.0987654320988, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1788849, Length=243, Percent_Identity=28.8065843621399, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI87082096, Length=253, Percent_Identity=27.6679841897233, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI87081881, Length=176, Percent_Identity=38.0681818181818, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI87082007, Length=188, Percent_Identity=31.3829787234043, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI145693134, Length=172, Percent_Identity=34.3023255813954, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787262, Length=167, Percent_Identity=34.7305389221557, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87081977, Length=161, Percent_Identity=32.2981366459627, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786584, Length=194, Percent_Identity=28.8659793814433, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787802, Length=168, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788956, Length=153, Percent_Identity=32.0261437908497, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787816, Length=180, Percent_Identity=31.1111111111111, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788521, Length=118, Percent_Identity=35.5932203389831, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788085, Length=163, Percent_Identity=31.2883435582822, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787229, Length=126, Percent_Identity=31.7460317460317, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787410, Length=163, Percent_Identity=28.8343558282209, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786599, Length=197, Percent_Identity=23.8578680203046, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1790863, Length=121, Percent_Identity=34.7107438016529, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI87081974, Length=164, Percent_Identity=29.2682926829268, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 85319; Mature: 85319

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLNTTTRAALERHDRPHSILIVDDEPRMRTSLRILLQESGREILESKSGGEAIATLKT
CCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHCCCCCCEEEEEEE
KQIDLVLLDIILPDISGLDVLEWITSRGDALPASVIIVSVDDNIDSAIHALRNGASEYIR
CCCCEEEEEHHHCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHCCHHHHHC
KPYEPEVIQHKVRNILYRRHLERDHVLITSRLQHSEQLHRFLVESSPDLIFTLDNSGCFT
CCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHH
FINSRIESLLGFSREELIGSCYDTIVLAEDLKTAQHPFTERRRGNRATTNLEIRLKCTPS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEEECHH
HYRNFENHHIVVMMSSTGIYGEHDNDFPLARCFSGTYGVARDITDRKIAEETIAFQAFHD
HHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHH
HLTHLPNQRLFKDRLEMAITHSKRHGGMVGVMFIDLDRFKIVNDTHGHAAGDELLKNVAH
HHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCEEEECCCCCCCHHHHHHHHHHH
RLRHCIRAVDTLARKGGDEFTVLLPDLMRAEDAALIAEKIMHELGIPFSVAGQKFHVSAS
HHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEE
IGIAIVPRDGESIDTLLKSADIAMYRVKASGKNGYRFFTPDMNICYTKRISLENELRQAI
CCEEEEECCCCHHHHHHHHCCEEEEEEEECCCCCCEEECCCCCEEEEEECCHHHHHHHHC
PNSEFELFYQPQVSINGASIIGLEALIRWRHPTHGLLNPGDFIELAEETGMIGTITDWVL
CCCCCEEEECCCEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEEHHHHHHH
AEACRQLAHWRSMGFSDLRIAVNVSPKEFERDDMVEQLSRFMSTFQLPPDSLEVEITEKI
HHHHHHHHHHHHCCCCCEEEEEECCHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEEHHH
LLRDTPSVINKMKTLRERGIRISIDDFGTCYSSLNYLRQFPISTIKIDQSFVRDLSEEHR
HHCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHH
ISPIIQAIIGIANGFGLHLLAEGVETHCQMQTLHALGCNEMQGYLFSRPAPAEQIEQMLC
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEECCCCCHHHHHHHHH
HTISHTTLQSPDFLTHPQLLSPLLTQGLQERPLA
HHHHHCCCCCCCCCCCHHHHHHHHHCCHHHCCCC
>Mature Secondary Structure
MNSLNTTTRAALERHDRPHSILIVDDEPRMRTSLRILLQESGREILESKSGGEAIATLKT
CCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHCCCCCCEEEEEEE
KQIDLVLLDIILPDISGLDVLEWITSRGDALPASVIIVSVDDNIDSAIHALRNGASEYIR
CCCCEEEEEHHHCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHCCHHHHHC
KPYEPEVIQHKVRNILYRRHLERDHVLITSRLQHSEQLHRFLVESSPDLIFTLDNSGCFT
CCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHH
FINSRIESLLGFSREELIGSCYDTIVLAEDLKTAQHPFTERRRGNRATTNLEIRLKCTPS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEEECHH
HYRNFENHHIVVMMSSTGIYGEHDNDFPLARCFSGTYGVARDITDRKIAEETIAFQAFHD
HHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHH
HLTHLPNQRLFKDRLEMAITHSKRHGGMVGVMFIDLDRFKIVNDTHGHAAGDELLKNVAH
HHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCEEEECCCCCCCHHHHHHHHHHH
RLRHCIRAVDTLARKGGDEFTVLLPDLMRAEDAALIAEKIMHELGIPFSVAGQKFHVSAS
HHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEE
IGIAIVPRDGESIDTLLKSADIAMYRVKASGKNGYRFFTPDMNICYTKRISLENELRQAI
CCEEEEECCCCHHHHHHHHCCEEEEEEEECCCCCCEEECCCCCEEEEEECCHHHHHHHHC
PNSEFELFYQPQVSINGASIIGLEALIRWRHPTHGLLNPGDFIELAEETGMIGTITDWVL
CCCCCEEEECCCEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEEHHHHHHH
AEACRQLAHWRSMGFSDLRIAVNVSPKEFERDDMVEQLSRFMSTFQLPPDSLEVEITEKI
HHHHHHHHHHHHCCCCCEEEEEECCHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEEHHH
LLRDTPSVINKMKTLRERGIRISIDDFGTCYSSLNYLRQFPISTIKIDQSFVRDLSEEHR
HHCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHH
ISPIIQAIIGIANGFGLHLLAEGVETHCQMQTLHALGCNEMQGYLFSRPAPAEQIEQMLC
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEECCCCCHHHHHHHHH
HTISHTTLQSPDFLTHPQLLSPLLTQGLQERPLA
HHHHHCCCCCCCCCCCHHHHHHHHHCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]