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The map label for this gene is hetI [H]

Identifier: 118581520

GI number: 118581520

Start: 3421908

End: 3422636

Strand: Direct

Name: hetI [H]

Synonym: Ppro_3119

Alternate gene names: 118581520

Gene position: 3421908-3422636 (Clockwise)

Preceding gene: 118581519

Following gene: 118581521

Centisome position: 85.38

GC content: 66.53

Gene sequence:

>729_bases
ATGGCCACCTCCCCACGCCAGCACTCCCCGCTGTCTCTCCCTCCCCAAGGCGACATCCATCTCCTGCTCGTCCGCCTCTC
CAGCATAACCGGGGTGGACCAGGCCCCTACGATCCTCTCCCCCGACGAACTGGCCCGCGCCAACCGTCTGCTCTGCCACG
AGGCCAGGGAACGTTTCATCGCCGGCCGCCTCTTCCTGCGCCGCAGCCTGGGGCGCTGTCTGGGTCTGAACCCGGCCGGT
ATCCTGCTGGTAGTGAACGAATGGGGAAAACCGCGCCTGGGGGGAGAGCAGGCGGCCAGCGGGCTCTGCTTCAACCTCGC
CCATACGGATGACTGGGCCATCCTGGCCCTGAGCCAGGGGTGCGAAGTGGGGGTGGATATTGAGTTAGTTCGGGAGGAGT
TGGAGTTTGGGCCCATGGCGCGGCGCTTCTTCTCAGCCTGCGAACGGGAGCAGCTCTTCGGTCTGGCCCAGGAACAGCAG
CTATCGGCCTTCTATTGCTGCTGGACCCGCAAGGAGGCCTACCTGAAAGGGGTGGGCTGCGGCCTGTCCCTTCCCACGGA
CAGCTTCGACGTCTCCCTGCTTCCCGGCCATGCCCCGCGTCTCATGGAGCAACGCCGGGACCCGGCGGAGATTGACCGCT
GGAGTCTGGCCGACATCCCCCTCCCCCCCGGCCTGTGCGGGGCTCTGGCGGTGAAGGGGAGCATCGGAGCGGTCAGGTTC
ATTGACTGA

Upstream 100 bases:

>100_bases
GCTGCCCGCCGCGATCTGGGGTATCAGCCGGAAGTCACCCTGGAGGAGGGGTTCCGGCGCCTCCGGGAATGGCTCTCCCG
CAGCCGGATCTGACCTTCCC

Downstream 100 bases:

>100_bases
GGGAGGGTTCGATAGGTTGGCTGCAAATGCGAAGAGCGCTTGGCTCTGGACAAAGGTAAATTACAGGCTCTTCGCTGTTT
CAAGTGGGTTGAGGGTATAG

Product: 4'-phosphopantetheinyl transferase

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MATSPRQHSPLSLPPQGDIHLLLVRLSSITGVDQAPTILSPDELARANRLLCHEARERFIAGRLFLRRSLGRCLGLNPAG
ILLVVNEWGKPRLGGEQAASGLCFNLAHTDDWAILALSQGCEVGVDIELVREELEFGPMARRFFSACEREQLFGLAQEQQ
LSAFYCCWTRKEAYLKGVGCGLSLPTDSFDVSLLPGHAPRLMEQRRDPAEIDRWSLADIPLPPGLCGALAVKGSIGAVRF
ID

Sequences:

>Translated_242_residues
MATSPRQHSPLSLPPQGDIHLLLVRLSSITGVDQAPTILSPDELARANRLLCHEARERFIAGRLFLRRSLGRCLGLNPAG
ILLVVNEWGKPRLGGEQAASGLCFNLAHTDDWAILALSQGCEVGVDIELVREELEFGPMARRFFSACEREQLFGLAQEQQ
LSAFYCCWTRKEAYLKGVGCGLSLPTDSFDVSLLPGHAPRLMEQRRDPAEIDRWSLADIPLPPGLCGALAVKGSIGAVRF
ID
>Mature_241_residues
ATSPRQHSPLSLPPQGDIHLLLVRLSSITGVDQAPTILSPDELARANRLLCHEARERFIAGRLFLRRSLGRCLGLNPAGI
LLVVNEWGKPRLGGEQAASGLCFNLAHTDDWAILALSQGCEVGVDIELVREELEFGPMARRFFSACEREQLFGLAQEQQL
SAFYCCWTRKEAYLKGVGCGLSLPTDSFDVSLLPGHAPRLMEQRRDPAEIDRWSLADIPLPPGLCGALAVKGSIGAVRFI
D

Specific function: Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differenti

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Escherichia coli, GI1789886, Length=124, Percent_Identity=36.2903225806452, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 26512; Mature: 26381

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSPRQHSPLSLPPQGDIHLLLVRLSSITGVDQAPTILSPDELARANRLLCHEARERFI
CCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AGRLFLRRSLGRCLGLNPAGILLVVNEWGKPRLGGEQAASGLCFNLAHTDDWAILALSQG
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHCCEEEEECCCCCEEEEEECCC
CEVGVDIELVREELEFGPMARRFFSACEREQLFGLAQEQQLSAFYCCWTRKEAYLKGVGC
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHCCEEEEEECCCHHHHHCCCC
GLSLPTDSFDVSLLPGHAPRLMEQRRDPAEIDRWSLADIPLPPGLCGALAVKGSIGAVRF
CCCCCCCCCEEEECCCCCHHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHCCCCCCEEEE
ID
CC
>Mature Secondary Structure 
ATSPRQHSPLSLPPQGDIHLLLVRLSSITGVDQAPTILSPDELARANRLLCHEARERFI
CCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AGRLFLRRSLGRCLGLNPAGILLVVNEWGKPRLGGEQAASGLCFNLAHTDDWAILALSQG
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHCCEEEEECCCCCEEEEEECCC
CEVGVDIELVREELEFGPMARRFFSACEREQLFGLAQEQQLSAFYCCWTRKEAYLKGVGC
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHCCEEEEEECCCHHHHHCCCC
GLSLPTDSFDVSLLPGHAPRLMEQRRDPAEIDRWSLADIPLPPGLCGALAVKGSIGAVRF
CCCCCCCCCEEEECCCCCHHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHCCCCCCEEEE
ID
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840; 8939709 [H]