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The map label for this gene is gatA

Identifier: 118581491

GI number: 118581491

Start: 3376630

End: 3378087

Strand: Direct

Name: gatA

Synonym: Ppro_3088

Alternate gene names: 118581491

Gene position: 3376630-3378087 (Clockwise)

Preceding gene: 118581490

Following gene: 118581492

Centisome position: 84.25

GC content: 64.81

Gene sequence:

>1458_bases
ATGGATCTTTTCGACCTCACCCTACATGAACTGCACGCAAAACTGAAGAGCAAAGAGGTTTCCTCCCGCGAGGCGACTTC
GGCCATGCTGGACCGCATCGCGGAACTGGAACCCCGGATCAACGCGTTCATCACCGTCACGCCGGAACGCGCCCTGGCCG
AGGCCGAGGCGGCGGACCGGCGCATCGCGGCGGGTGAGGCGGACGTCCTGACCGGCATACCGCTGGCAGTCAAGGATATC
TTCCTCACCGAAGGGACGCTCACCACCTGCGGTTCCCGTATCCTCAACAATTTTATCCCCCCCTACAGCGCAACCTCCTT
CGAGAAGCTGAAGCAGCGGGGGATGGTCCTGCTGGGAAAACTGAACCAGGACGAGTTTGCCATGGGATCGTCCAACGAGT
CCAGCGCTTCCGGCCCGTGCCGCAACCCCTGGAACACGGACTGCATCCCGGGAGGCTCTTCGGGCGGTTCGGCCGCGGCA
ATCGCGGCCCGCCAGGCCACGGTCACCCTGGGCACGGATACCGGCGGTTCCATCCGCCAACCGGCCTCCCACTGCGGCTG
CGTGGGGCTCAAACCGACCTACGGCCGGGTCTCGCGCTACGGCGTGATCGCCTACGCCTCCTCCCTGGACCAGGTAGGGC
CGCTAACCCGGGATGTCACCGACTGCGCCATCATGCTCGGCGCCTTGGCCGGCCACGACCCCAAGGACTCAACCAGCGTC
GACAGGCCGGTTCCCGATTACCAGGCTGCCCTGACCAACGACATCAGGGGGCTCAGGATCGGCCTGCCCAGGGAATACTT
CATCGAGGGGCTCGACCCGGACGTCCAGGCATCCATGGACCAAGCCATCGAGACCTACCGCCGCCTGGGAGCCGAGTTCA
CTGAGATATCCCTCCCCCACACCGACTATGCCGTGGCCAGCTACTACCTGATAGCCACCGCCGAGGCAAGCGCCAACCTG
GCCCGCTACGACGGCGTCCGCTTCGGCCATCGCGCCGAGCAGGCCGAGGGGCTGCTGGAGATGTACTCCCGGAGCCGCAG
CCAGGGCTTCGGCAGCGAGGTCAAACGCCGCATCATGCTGGGAACCTACGCCCTCTCCTCCGGCTACTACGACGCTTACT
ACCTCAAGGCCCAAAAGGTGCGGACTCTGATCATGGCCGACTTCATCCAGGCCTTCGAGGGAGTCGACCTAATCCTGACC
CCTGTTGCCCCCACACCGGCCTTCAGGATCGGAGAAAAGGTCAACGATCCCCTGCAGATGTACCTCTCCGACATTTTCAC
CATTCCGGTCAACCTGGCAGGGACCTGCGCCATGTCACTGCCGGCCGGCATCAGCGGGCAGGGTTTGCCCATCGGCGTAC
AGTTGATCGGCAAGCCGTTCGGCGAGGAGACCATCCTGCGGGCGGCCCACGCCTTCGAGCAAGCCACCGAATGGCACAGC
CTGAGGGCGCCGCTGTAG

Upstream 100 bases:

>100_bases
ACCGCGAAGGCCCTGGCCAATGCGCCGGATCCGGTTCTGGGGTTCTTCCGCGTCCCTAAGGTTATCGAATAATAACATAC
TCGCACACTGGAGCCAGTGA

Downstream 100 bases:

>100_bases
GGGCGGCCCCTGTGACTGCCACCAAGGGTAACCACACGGAGTTACCCCAACACTGACTTCGGAGAACCGTTCACATGAAA
TACCAAGCCGTTATCGGACT

Product: aspartyl/glutamyl-tRNA amidotransferase subunit A

Products: NA

Alternate protein names: Glu-ADT subunit A

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MDLFDLTLHELHAKLKSKEVSSREATSAMLDRIAELEPRINAFITVTPERALAEAEAADRRIAAGEADVLTGIPLAVKDI
FLTEGTLTTCGSRILNNFIPPYSATSFEKLKQRGMVLLGKLNQDEFAMGSSNESSASGPCRNPWNTDCIPGGSSGGSAAA
IAARQATVTLGTDTGGSIRQPASHCGCVGLKPTYGRVSRYGVIAYASSLDQVGPLTRDVTDCAIMLGALAGHDPKDSTSV
DRPVPDYQAALTNDIRGLRIGLPREYFIEGLDPDVQASMDQAIETYRRLGAEFTEISLPHTDYAVASYYLIATAEASANL
ARYDGVRFGHRAEQAEGLLEMYSRSRSQGFGSEVKRRIMLGTYALSSGYYDAYYLKAQKVRTLIMADFIQAFEGVDLILT
PVAPTPAFRIGEKVNDPLQMYLSDIFTIPVNLAGTCAMSLPAGISGQGLPIGVQLIGKPFGEETILRAAHAFEQATEWHS
LRAPL

Sequences:

>Translated_485_residues
MDLFDLTLHELHAKLKSKEVSSREATSAMLDRIAELEPRINAFITVTPERALAEAEAADRRIAAGEADVLTGIPLAVKDI
FLTEGTLTTCGSRILNNFIPPYSATSFEKLKQRGMVLLGKLNQDEFAMGSSNESSASGPCRNPWNTDCIPGGSSGGSAAA
IAARQATVTLGTDTGGSIRQPASHCGCVGLKPTYGRVSRYGVIAYASSLDQVGPLTRDVTDCAIMLGALAGHDPKDSTSV
DRPVPDYQAALTNDIRGLRIGLPREYFIEGLDPDVQASMDQAIETYRRLGAEFTEISLPHTDYAVASYYLIATAEASANL
ARYDGVRFGHRAEQAEGLLEMYSRSRSQGFGSEVKRRIMLGTYALSSGYYDAYYLKAQKVRTLIMADFIQAFEGVDLILT
PVAPTPAFRIGEKVNDPLQMYLSDIFTIPVNLAGTCAMSLPAGISGQGLPIGVQLIGKPFGEETILRAAHAFEQATEWHS
LRAPL
>Mature_485_residues
MDLFDLTLHELHAKLKSKEVSSREATSAMLDRIAELEPRINAFITVTPERALAEAEAADRRIAAGEADVLTGIPLAVKDI
FLTEGTLTTCGSRILNNFIPPYSATSFEKLKQRGMVLLGKLNQDEFAMGSSNESSASGPCRNPWNTDCIPGGSSGGSAAA
IAARQATVTLGTDTGGSIRQPASHCGCVGLKPTYGRVSRYGVIAYASSLDQVGPLTRDVTDCAIMLGALAGHDPKDSTSV
DRPVPDYQAALTNDIRGLRIGLPREYFIEGLDPDVQASMDQAIETYRRLGAEFTEISLPHTDYAVASYYLIATAEASANL
ARYDGVRFGHRAEQAEGLLEMYSRSRSQGFGSEVKRRIMLGTYALSSGYYDAYYLKAQKVRTLIMADFIQAFEGVDLILT
PVAPTPAFRIGEKVNDPLQMYLSDIFTIPVNLAGTCAMSLPAGISGQGLPIGVQLIGKPFGEETILRAAHAFEQATEWHS
LRAPL

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family

Homologues:

Organism=Homo sapiens, GI222831590, Length=497, Percent_Identity=42.6559356136821, Blast_Score=364, Evalue=1e-101,
Organism=Homo sapiens, GI195972892, Length=493, Percent_Identity=24.7464503042596, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17543272, Length=440, Percent_Identity=39.7727272727273, Blast_Score=285, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI17537465, Length=493, Percent_Identity=23.7322515212982, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17556264, Length=311, Percent_Identity=26.3665594855305, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71990152, Length=321, Percent_Identity=26.791277258567, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17556276, Length=239, Percent_Identity=30.5439330543933, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17556278, Length=239, Percent_Identity=30.5439330543933, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538252, Length=517, Percent_Identity=22.6305609284333, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323950, Length=460, Percent_Identity=34.1304347826087, Blast_Score=243, Evalue=5e-65,
Organism=Saccharomyces cerevisiae, GI6319685, Length=463, Percent_Identity=27.2138228941685, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320448, Length=224, Percent_Identity=33.0357142857143, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648113, Length=492, Percent_Identity=38.4146341463415, Blast_Score=315, Evalue=4e-86,
Organism=Drosophila melanogaster, GI24652985, Length=498, Percent_Identity=25.7028112449799, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI19922090, Length=498, Percent_Identity=25.7028112449799, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24652981, Length=498, Percent_Identity=25.7028112449799, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24652983, Length=498, Percent_Identity=25.7028112449799, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24644968, Length=494, Percent_Identity=24.8987854251012, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI161078093, Length=504, Percent_Identity=26.5873015873016, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI45550774, Length=508, Percent_Identity=23.4251968503937, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24648435, Length=508, Percent_Identity=23.4251968503937, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24648437, Length=508, Percent_Identity=23.4251968503937, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21356731, Length=486, Percent_Identity=23.4567901234568, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24648441, Length=437, Percent_Identity=22.883295194508, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648439, Length=437, Percent_Identity=22.883295194508, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GATA_PELPD (A1ATL3)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902741.1
- ProteinModelPortal:   A1ATL3
- SMR:   A1ATL3
- STRING:   A1ATL3
- GeneID:   4573961
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_3088
- eggNOG:   COG0154
- HOGENOM:   HBG481888
- OMA:   RWGLIAF
- PhylomeDB:   A1ATL3
- ProtClustDB:   PRK00012
- GO:   GO:0006412
- HAMAP:   MF_00120
- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412
- Gene3D:   G3DSA:3.90.1300.10
- PANTHER:   PTHR11895
- TIGRFAMs:   TIGR00132

Pfam domain/function: PF01425 Amidase; SSF75304 Amidase_sig_enz

EC number: 6.3.5.-

Molecular weight: Translated: 52259; Mature: 52259

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00571 AMIDASES

Important sites: ACT_SITE 78-78 ACT_SITE 153-153 ACT_SITE 177-177

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFDLTLHELHAKLKSKEVSSREATSAMLDRIAELEPRINAFITVTPERALAEAEAADR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCC
RIAAGEADVLTGIPLAVKDIFLTEGTLTTCGSRILNNFIPPYSATSFEKLKQRGMVLLGK
CCCCCCCHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCEEEEEE
LNQDEFAMGSSNESSASGPCRNPWNTDCIPGGSSGGSAAAIAARQATVTLGTDTGGSIRQ
CCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEEEEEEECCCCCCCCC
PASHCGCVGLKPTYGRVSRYGVIAYASSLDQVGPLTRDVTDCAIMLGALAGHDPKDSTSV
CHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC
DRPVPDYQAALTNDIRGLRIGLPREYFIEGLDPDVQASMDQAIETYRRLGAEFTEISLPH
CCCCCHHHHHHHHCCCCEEECCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHEECCCC
TDYAVASYYLIATAEASANLARYDGVRFGHRAEQAEGLLEMYSRSRSQGFGSEVKRRIML
CCHHHHEEEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GTYALSSGYYDAYYLKAQKVRTLIMADFIQAFEGVDLILTPVAPTPAFRIGEKVNDPLQM
HHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCHHHHH
YLSDIFTIPVNLAGTCAMSLPAGISGQGLPIGVQLIGKPFGEETILRAAHAFEQATEWHS
HHHHHHHCCCCCCCHHHCCCCCCCCCCCCEEEHEEECCCCCHHHHHHHHHHHHHHHHHHH
LRAPL
HCCCC
>Mature Secondary Structure
MDLFDLTLHELHAKLKSKEVSSREATSAMLDRIAELEPRINAFITVTPERALAEAEAADR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCC
RIAAGEADVLTGIPLAVKDIFLTEGTLTTCGSRILNNFIPPYSATSFEKLKQRGMVLLGK
CCCCCCCHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCEEEEEE
LNQDEFAMGSSNESSASGPCRNPWNTDCIPGGSSGGSAAAIAARQATVTLGTDTGGSIRQ
CCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEEEEEEECCCCCCCCC
PASHCGCVGLKPTYGRVSRYGVIAYASSLDQVGPLTRDVTDCAIMLGALAGHDPKDSTSV
CHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC
DRPVPDYQAALTNDIRGLRIGLPREYFIEGLDPDVQASMDQAIETYRRLGAEFTEISLPH
CCCCCHHHHHHHHCCCCEEECCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHEECCCC
TDYAVASYYLIATAEASANLARYDGVRFGHRAEQAEGLLEMYSRSRSQGFGSEVKRRIML
CCHHHHEEEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GTYALSSGYYDAYYLKAQKVRTLIMADFIQAFEGVDLILTPVAPTPAFRIGEKVNDPLQM
HHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCHHHHH
YLSDIFTIPVNLAGTCAMSLPAGISGQGLPIGVQLIGKPFGEETILRAAHAFEQATEWHS
HHHHHHHCCCCCCCHHHCCCCCCCCCCCCEEEHEEECCCCCHHHHHHHHHHHHHHHHHHH
LRAPL
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA