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The map label for this gene is virA [H]

Identifier: 118581407

GI number: 118581407

Start: 3273843

End: 3276134

Strand: Direct

Name: virA [H]

Synonym: Ppro_3002

Alternate gene names: 118581407

Gene position: 3273843-3276134 (Clockwise)

Preceding gene: 118581406

Following gene: 118581411

Centisome position: 81.68

GC content: 63.79

Gene sequence:

>2292_bases
GTGGCTGCGCTCTGCGCAGGCTTACCTCCCCGGCCAGGAGAGAGACCGTTCCTGCTGCTTCTGCTGTCACCCCTGCTGCT
GGGACTCACCCTCTCCCCCCTTCAGGCCCACGAGATCTATCCCGCCCCCACCGCGACCAGCGTCGCCTTACCCATACGCA
TCGGCGCCCTGGCCAACCGGGGGAGGGAGGAGTGCATCAGGCGCTGGAAACCGACCGCCACGTACCTGGAACACCACCTG
GGGGGGAGCAGGTTCGAGATCGTCCCCCTCGACTTCGGTCAGGTTGCGCAAAAGGTCGCATCGGAAGAGGTACAGTTCAT
CATCACCAACCCGGTGCAGTACGCCCAGCTGGAATTCAGCGGCAAGGCGTACCGCATCGCCGGTTTCCAACTCCCCTCCC
TCAACGGCCCCCAGGGAGTGTACGGCGGCGTCATCTTCACCCGCGCCGACCGGAAAGACATCCGGACCCTGTCCGACCTG
AAGGGCAAGAAATTCTCAGCCGTGGACTCGGAATCACTGGGAGGGTGGCTTTGCGCCAGGCGGGAACTGCATGGCGCCCG
GCTGAAGCCGGAGCGGGATTTCGCGAACCTTCGATTTGCCGGCACCCATGACGCGGTAGTGCGGGACGTCGTCTCCGGAA
CCAGCGACGCCGGAACCATCCGCAGCAGCCAGCTGGAAACCATGGCTGCCCAGGGAAAGATGGACCTGCGCTCCATCCGG
GTCATCCCGCCCGCGCGTCCGGTCAGAGGTTACCCCTTTCTGCTCTCCACGCGCCTCTACCCGGAATGGCCCTTCGCCGT
TGTCAGCGGCACAAACGACGAACTGTCCCGGCGGGTCGCGATCGCCCTGATGACCATGCGGCCGGACGACCCGACGGCGC
TGGCCTCGGGAGGAAGCGGCTGGACCATTCCGGCGGATTACTCCGCTGTCCATGAGCTGTTGAGGGAGCTCCGCCTGGGG
CCCTACCGGGACATGGGCAGGATCACACTCGGTCAGGTTATCACCCACTACCGCACGCATCTGCTGGCCATCACCGTCGC
GGCTTCCCTGATCGCGCTGTTCGCGTTCAGGTCGCTGTTACTGAACCGCCGTCTCAGGGCGTCGCTTGCGGAACTGTCCC
AGCGGACCAGCGAACTGAACGAATCCCGAGAGAACCTGCGCAACGAGCGGGACAACCTGGTCGCCATCTTCGAGGCCATG
CAGGACGACATCTACATTTCTGACTCGAACCACACCATACTGTACGGCAACGACGCCCTTGCCCGGGACTTCGGCGACTG
GAGGGGGCGCATCTGTCATGACTATCTGGATGACCGCACGTCCCCCTGTCTCGACTGCCGTCTCCGGGAGGTGCAAGCAG
GCGCAACCGTGCGGCGTGAGCAGTTTTTTCCCAAGAGCGGCAAAACCTACGACATCATCGAGACCCCGCTGAGACAATCC
GGCCGAACCGTCAAGCTGACCATCTTCCGCGATGTCACGGAACTGAGAGCCATGGAGGCCGAGCGCCTGGCGATGGAGCG
ACGACTGCTGCACTCCCAGAAACTGGAGAGCCTGGGGATTCTGGCCGGCGGCATCGCCCACGACTTCAACAACCTCCTCA
CGGTCATCATCGGCAATCTGGACCTGGTCCGACGGCGGCTTCTCCCTGACTCACCCACCCGAGGCAACATCGAATCCGCC
CAGGCTGCATGCCAGCAGGCAGCCAAACTCATCGGACAGATTCTTGATTACACCGGCAAGATGCCGGTCATAGCGGACAG
CATCGACCTCAACGATCTCCTCCGGCACAACGAGGCGCTCCTGCGCGGCTCGCTGCCGGAAAACGTCACACTCACCATCA
GCATCTCGGACGGCATCCCCCGTATCAGGGGAGACCGGAGCCGGATCGAGCAGGTGGTCATGAACCTGCTGGCCAACGGG
GTGGAAGCGGTGGGGGATGCACCGGGGTCCATAGCCATCACAACCGGCGTACGGGAGTGCGATGACAGCTACCTGGCGCA
GAGCAGGATCGAAGACAAGCCGCCAGCAGGCAGGTTTGTCTATCTGGAGGTGGCGGACAGCGGCTGCGGCATGACTCGAG
AAACCGAGGTGCGGCTCTTCGAGCCGTTCTTCACGACCAAGTTCATGGGCCGCGGGCTGGGGTTGTCGGCGGTCCAGGGG
ATCGTGAAGATGCATGGGGGGGCGATCTTGCTGGAGAACAGGCAGGGACGAGGGAGTGTCTTCCGCGTCCTGTTTCCCGC
CAATGGCCCGGCCGACTCCCCTCACCCCTCTTCTCTCAGGAGCGGGCTGTAA

Upstream 100 bases:

>100_bases
TAGCAGGGCAGGCCGCATCCGCTGAAAGGAGAAAGAGGTGAGGAGAAGAGCTTCGCTTCCAACGCTCGCAGCGCTGCTCA
GCGCTGTTTCAGCCACCCTC

Downstream 100 bases:

>100_bases
AGCGGTACGGACCGATCCGTTCAGAGCTTGGGCAGGCAGACGAACAAGAGCATCGACAGAAGCGCCAGCACCCACATGCC
CGGCTTGACCTCGCCCCCCC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: WHR virA [H]

Number of amino acids: Translated: 763; Mature: 762

Protein sequence:

>763_residues
MAALCAGLPPRPGERPFLLLLLSPLLLGLTLSPLQAHEIYPAPTATSVALPIRIGALANRGREECIRRWKPTATYLEHHL
GGSRFEIVPLDFGQVAQKVASEEVQFIITNPVQYAQLEFSGKAYRIAGFQLPSLNGPQGVYGGVIFTRADRKDIRTLSDL
KGKKFSAVDSESLGGWLCARRELHGARLKPERDFANLRFAGTHDAVVRDVVSGTSDAGTIRSSQLETMAAQGKMDLRSIR
VIPPARPVRGYPFLLSTRLYPEWPFAVVSGTNDELSRRVAIALMTMRPDDPTALASGGSGWTIPADYSAVHELLRELRLG
PYRDMGRITLGQVITHYRTHLLAITVAASLIALFAFRSLLLNRRLRASLAELSQRTSELNESRENLRNERDNLVAIFEAM
QDDIYISDSNHTILYGNDALARDFGDWRGRICHDYLDDRTSPCLDCRLREVQAGATVRREQFFPKSGKTYDIIETPLRQS
GRTVKLTIFRDVTELRAMEAERLAMERRLLHSQKLESLGILAGGIAHDFNNLLTVIIGNLDLVRRRLLPDSPTRGNIESA
QAACQQAAKLIGQILDYTGKMPVIADSIDLNDLLRHNEALLRGSLPENVTLTISISDGIPRIRGDRSRIEQVVMNLLANG
VEAVGDAPGSIAITTGVRECDDSYLAQSRIEDKPPAGRFVYLEVADSGCGMTRETEVRLFEPFFTTKFMGRGLGLSAVQG
IVKMHGGAILLENRQGRGSVFRVLFPANGPADSPHPSSLRSGL

Sequences:

>Translated_763_residues
MAALCAGLPPRPGERPFLLLLLSPLLLGLTLSPLQAHEIYPAPTATSVALPIRIGALANRGREECIRRWKPTATYLEHHL
GGSRFEIVPLDFGQVAQKVASEEVQFIITNPVQYAQLEFSGKAYRIAGFQLPSLNGPQGVYGGVIFTRADRKDIRTLSDL
KGKKFSAVDSESLGGWLCARRELHGARLKPERDFANLRFAGTHDAVVRDVVSGTSDAGTIRSSQLETMAAQGKMDLRSIR
VIPPARPVRGYPFLLSTRLYPEWPFAVVSGTNDELSRRVAIALMTMRPDDPTALASGGSGWTIPADYSAVHELLRELRLG
PYRDMGRITLGQVITHYRTHLLAITVAASLIALFAFRSLLLNRRLRASLAELSQRTSELNESRENLRNERDNLVAIFEAM
QDDIYISDSNHTILYGNDALARDFGDWRGRICHDYLDDRTSPCLDCRLREVQAGATVRREQFFPKSGKTYDIIETPLRQS
GRTVKLTIFRDVTELRAMEAERLAMERRLLHSQKLESLGILAGGIAHDFNNLLTVIIGNLDLVRRRLLPDSPTRGNIESA
QAACQQAAKLIGQILDYTGKMPVIADSIDLNDLLRHNEALLRGSLPENVTLTISISDGIPRIRGDRSRIEQVVMNLLANG
VEAVGDAPGSIAITTGVRECDDSYLAQSRIEDKPPAGRFVYLEVADSGCGMTRETEVRLFEPFFTTKFMGRGLGLSAVQG
IVKMHGGAILLENRQGRGSVFRVLFPANGPADSPHPSSLRSGL
>Mature_762_residues
AALCAGLPPRPGERPFLLLLLSPLLLGLTLSPLQAHEIYPAPTATSVALPIRIGALANRGREECIRRWKPTATYLEHHLG
GSRFEIVPLDFGQVAQKVASEEVQFIITNPVQYAQLEFSGKAYRIAGFQLPSLNGPQGVYGGVIFTRADRKDIRTLSDLK
GKKFSAVDSESLGGWLCARRELHGARLKPERDFANLRFAGTHDAVVRDVVSGTSDAGTIRSSQLETMAAQGKMDLRSIRV
IPPARPVRGYPFLLSTRLYPEWPFAVVSGTNDELSRRVAIALMTMRPDDPTALASGGSGWTIPADYSAVHELLRELRLGP
YRDMGRITLGQVITHYRTHLLAITVAASLIALFAFRSLLLNRRLRASLAELSQRTSELNESRENLRNERDNLVAIFEAMQ
DDIYISDSNHTILYGNDALARDFGDWRGRICHDYLDDRTSPCLDCRLREVQAGATVRREQFFPKSGKTYDIIETPLRQSG
RTVKLTIFRDVTELRAMEAERLAMERRLLHSQKLESLGILAGGIAHDFNNLLTVIIGNLDLVRRRLLPDSPTRGNIESAQ
AACQQAAKLIGQILDYTGKMPVIADSIDLNDLLRHNEALLRGSLPENVTLTISISDGIPRIRGDRSRIEQVVMNLLANGV
EAVGDAPGSIAITTGVRECDDSYLAQSRIEDKPPAGRFVYLEVADSGCGMTRETEVRLFEPFFTTKFMGRGLGLSAVQGI
VKMHGGAILLENRQGRGSVFRVLFPANGPADSPHPSSLRSGL

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=259, Percent_Identity=29.3436293436293, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1788549, Length=390, Percent_Identity=26.9230769230769, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI145693157, Length=336, Percent_Identity=25, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788713, Length=287, Percent_Identity=25.0871080139373, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1790300, Length=254, Percent_Identity=25.9842519685039, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1786912, Length=304, Percent_Identity=25.9868421052632, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790567, Length=366, Percent_Identity=24.5901639344262, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84143; Mature: 84011

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALCAGLPPRPGERPFLLLLLSPLLLGLTLSPLQAHEIYPAPTATSVALPIRIGALANR
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCEEEEEEEHHHHCC
GREECIRRWKPTATYLEHHLGGSRFEIVPLDFGQVAQKVASEEVQFIITNPVQYAQLEFS
CHHHHHHHCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCEEEEEECCCEEEEEEEC
GKAYRIAGFQLPSLNGPQGVYGGVIFTRADRKDIRTLSDLKGKKFSAVDSESLGGWLCAR
CCEEEEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCEECCCCCCCCCHHHHHH
RELHGARLKPERDFANLRFAGTHDAVVRDVVSGTSDAGTIRSSQLETMAAQGKMDLRSIR
HHHCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHEEE
VIPPARPVRGYPFLLSTRLYPEWPFAVVSGTNDELSRRVAIALMTMRPDDPTALASGGSG
ECCCCCCCCCCCEEEECCCCCCCCEEEEECCCHHHHHEEEEEEEEECCCCCCCCCCCCCC
WTIPADYSAVHELLRELRLGPYRDMGRITLGQVITHYRTHLLAITVAASLIALFAFRSLL
CCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNRRLRASLAELSQRTSELNESRENLRNERDNLVAIFEAMQDDIYISDSNHTILYGNDAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCHH
ARDFGDWRGRICHDYLDDRTSPCLDCRLREVQAGATVRREQFFPKSGKTYDIIETPLRQS
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCEEHHHHCHHHHC
GRTVKLTIFRDVTELRAMEAERLAMERRLLHSQKLESLGILAGGIAHDFNNLLTVIIGNL
CCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
DLVRRRLLPDSPTRGNIESAQAACQQAAKLIGQILDYTGKMPVIADSIDLNDLLRHNEAL
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
LRGSLPENVTLTISISDGIPRIRGDRSRIEQVVMNLLANGVEAVGDAPGSIAITTGVREC
HCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCEEEECCCHHH
DDSYLAQSRIEDKPPAGRFVYLEVADSGCGMTRETEVRLFEPFFTTKFMGRGLGLSAVQG
CHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCEEEECHHHHHHHHCCCCCHHHHHH
IVKMHGGAILLENRQGRGSVFRVLFPANGPADSPHPSSLRSGL
HHHHCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHCCC
>Mature Secondary Structure 
AALCAGLPPRPGERPFLLLLLSPLLLGLTLSPLQAHEIYPAPTATSVALPIRIGALANR
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCEEEEEEEHHHHCC
GREECIRRWKPTATYLEHHLGGSRFEIVPLDFGQVAQKVASEEVQFIITNPVQYAQLEFS
CHHHHHHHCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCEEEEEECCCEEEEEEEC
GKAYRIAGFQLPSLNGPQGVYGGVIFTRADRKDIRTLSDLKGKKFSAVDSESLGGWLCAR
CCEEEEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCEECCCCCCCCCHHHHHH
RELHGARLKPERDFANLRFAGTHDAVVRDVVSGTSDAGTIRSSQLETMAAQGKMDLRSIR
HHHCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHEEE
VIPPARPVRGYPFLLSTRLYPEWPFAVVSGTNDELSRRVAIALMTMRPDDPTALASGGSG
ECCCCCCCCCCCEEEECCCCCCCCEEEEECCCHHHHHEEEEEEEEECCCCCCCCCCCCCC
WTIPADYSAVHELLRELRLGPYRDMGRITLGQVITHYRTHLLAITVAASLIALFAFRSLL
CCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNRRLRASLAELSQRTSELNESRENLRNERDNLVAIFEAMQDDIYISDSNHTILYGNDAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCHH
ARDFGDWRGRICHDYLDDRTSPCLDCRLREVQAGATVRREQFFPKSGKTYDIIETPLRQS
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCEEHHHHCHHHHC
GRTVKLTIFRDVTELRAMEAERLAMERRLLHSQKLESLGILAGGIAHDFNNLLTVIIGNL
CCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
DLVRRRLLPDSPTRGNIESAQAACQQAAKLIGQILDYTGKMPVIADSIDLNDLLRHNEAL
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
LRGSLPENVTLTISISDGIPRIRGDRSRIEQVVMNLLANGVEAVGDAPGSIAITTGVREC
HCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCEEEECCCHHH
DDSYLAQSRIEDKPPAGRFVYLEVADSGCGMTRETEVRLFEPFFTTKFMGRGLGLSAVQG
CHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCEEEECHHHHHHHHCCCCCHHHHHH
IVKMHGGAILLENRQGRGSVFRVLFPANGPADSPHPSSLRSGL
HHHHCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2796735; 2194232; 11743193; 11743194 [H]