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The map label for this gene is nudG [H]

Identifier: 118581389

GI number: 118581389

Start: 3254360

End: 3254770

Strand: Direct

Name: nudG [H]

Synonym: Ppro_2984

Alternate gene names: 118581389

Gene position: 3254360-3254770 (Clockwise)

Preceding gene: 118581388

Following gene: 118581390

Centisome position: 81.2

GC content: 67.15

Gene sequence:

>411_bases
ATGCCCCCTGCGCCCCTCCAGCGGCATATCCACGTGGCCTGCGCCATCATCGAGCATGGCGGCCTGGTTCTGGCTGCCCG
GCGCGGCGAAGCCATGAGCATGCCGCTGGTCTGGGAGTTTCCCGGGGGCAAAATCGAGGCGGGCGAGACTCCCCGGCAGT
GCCTGAGGCGTGAGCTGATGGAGGAACTGGGAATCGCCATCTCCGTGGGAGCGGCACTGGAACCGGTTACCCACGACTAC
CCATCCTTTACCGTCACCCTCTACCCCTTCGTCTGCACCATGGAAAGGGGGGAGATAACCCTGCACGAGCATGCCGCCAT
CGCCTGGCTGGCGCCGGAAGCGCTCCCCTCCCTGGAGTGGGCCGCCGCCGACGGTCCGATCCTGGAGAACTACCTGGGGC
AGCGCCGCTGA

Upstream 100 bases:

>100_bases
ACAAAAAAAAGCAGGCTGCTGGTGGGGGACAACCGGATCAATCCGGTAACGGTCAGGGCTGCCATCGCGGAAGTTGAGCG
CAACTGACCGCCGCCCGCCG

Downstream 100 bases:

>100_bases
CACCCCCTGCCTCGTCACGGCTCCAGGTTGCTGCCCATCTCCCGGGAAACCCTGTTCCCATGAAACGAGGTTGCCATGAA
ACGTCCCCTTGCCCTGTTCC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MPPAPLQRHIHVACAIIEHGGLVLAARRGEAMSMPLVWEFPGGKIEAGETPRQCLRRELMEELGIAISVGAALEPVTHDY
PSFTVTLYPFVCTMERGEITLHEHAAIAWLAPEALPSLEWAAADGPILENYLGQRR

Sequences:

>Translated_136_residues
MPPAPLQRHIHVACAIIEHGGLVLAARRGEAMSMPLVWEFPGGKIEAGETPRQCLRRELMEELGIAISVGAALEPVTHDY
PSFTVTLYPFVCTMERGEITLHEHAAIAWLAPEALPSLEWAAADGPILENYLGQRR
>Mature_135_residues
PPAPLQRHIHVACAIIEHGGLVLAARRGEAMSMPLVWEFPGGKIEAGETPRQCLRRELMEELGIAISVGAALEPVTHDYP
SFTVTLYPFVCTMERGEITLHEHAAIAWLAPEALPSLEWAAADGPILENYLGQRR

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=128, Percent_Identity=36.71875, Blast_Score=79, Evalue=9e-17,
Organism=Escherichia coli, GI1786288, Length=122, Percent_Identity=30.327868852459, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 14932; Mature: 14801

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPAPLQRHIHVACAIIEHGGLVLAARRGEAMSMPLVWEFPGGKIEAGETPRQCLRRELM
CCCCCCHHHHEEEEEEEECCCEEEEECCCCEECCCEEEECCCCEEECCCCHHHHHHHHHH
EELGIAISVGAALEPVTHDYPSFTVTLYPFVCTMERGEITLHEHAAIAWLAPEALPSLEW
HHCCCEEEECCCCCCCCCCCCCEEEEEEEEEEEEECCCEEEECCEEEEEECCCCCCCCCC
AAADGPILENYLGQRR
CCCCCCHHHHHCCCCC
>Mature Secondary Structure 
PPAPLQRHIHVACAIIEHGGLVLAARRGEAMSMPLVWEFPGGKIEAGETPRQCLRRELM
CCCCCHHHHEEEEEEEECCCEEEEECCCCEECCCEEEECCCCEEECCCCHHHHHHHHHH
EELGIAISVGAALEPVTHDYPSFTVTLYPFVCTMERGEITLHEHAAIAWLAPEALPSLEW
HHCCCEEEECCCCCCCCCCCCCEEEEEEEEEEEEECCCEEEECCEEEEEECCCCCCCCCC
AAADGPILENYLGQRR
CCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]